Result of FASTA (ccds) for
pFN21AE6337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6337, 385 aa
1>>>pF1KE6337 385 - 385 aa - 385 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5753+/-0.000987; mu= 15.3147+/- 0.059
mean_var=65.3076+/-12.899, 0's: 0 Z-trim(103.6): 18 B-trim: 16 in 1/48
Lambda= 0.158706
statistics sampled from 7476 (7487) to 7476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.23), width: 16
Scan time: 2.140
The best scores are: opt bits E(32554)
CCDS13032.1 IDH3B gene_id:3420|Hs108|chr20 ( 385) 2494 580.1 1.2e-165
CCDS82594.1 IDH3B gene_id:3420|Hs108|chr20 ( 387) 2494 580.1 1.2e-165
CCDS13031.1 IDH3B gene_id:3420|Hs108|chr20 ( 383) 2403 559.2 2.2e-159
CCDS74696.1 IDH3B gene_id:3420|Hs108|chr20 ( 376) 2319 540.0 1.3e-153
CCDS14730.1 IDH3G gene_id:3421|Hs108|chrX ( 393) 1169 276.7 2.5e-74
CCDS44019.1 IDH3G gene_id:3421|Hs108|chrX ( 380) 1115 264.3 1.3e-70
CCDS10297.1 IDH3A gene_id:3419|Hs108|chr15 ( 366) 941 224.5 1.2e-58
>>CCDS13032.1 IDH3B gene_id:3420|Hs108|chr20 (385 aa)
initn: 2494 init1: 2494 opt: 2494 Z-score: 3087.6 bits: 580.1 E(32554): 1.2e-165
Smith-Waterman score: 2494; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
:::::::::::::::::::::::::
CCDS13 RDMGGYSTTTDFIKSVIGHLQTKGS
370 380
>>CCDS82594.1 IDH3B gene_id:3420|Hs108|chr20 (387 aa)
initn: 2494 init1: 2494 opt: 2494 Z-score: 3087.5 bits: 580.1 E(32554): 1.2e-165
Smith-Waterman score: 2494; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
:::::::::::::::::::::::::
CCDS82 RDMGGYSTTTDFIKSVIGHLQTKGSNL
370 380
>>CCDS13031.1 IDH3B gene_id:3420|Hs108|chr20 (383 aa)
initn: 2427 init1: 2403 opt: 2403 Z-score: 2975.0 bits: 559.2 E(32554): 2.2e-159
Smith-Waterman score: 2403; 97.6% identity (98.7% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
:::::.: :: ..::. :
CCDS13 SDMGGYATCHDFTEAVIAALPHP
370 380
>>CCDS74696.1 IDH3B gene_id:3420|Hs108|chr20 (376 aa)
initn: 2319 init1: 2319 opt: 2319 Z-score: 2871.2 bits: 540.0 E(32554): 1.3e-153
Smith-Waterman score: 2319; 99.7% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS74 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPS
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
CCDS74 AVPSFLLHPLPFSWAI
370
>>CCDS14730.1 IDH3G gene_id:3421|Hs108|chrX (393 aa)
initn: 1190 init1: 1010 opt: 1169 Z-score: 1447.8 bits: 276.7 E(32554): 2.5e-74
Smith-Waterman score: 1169; 54.6% identity (78.5% similar) in 335 aa overlap (47-381:53-384)
20 30 40 50 60 70
pF1KE6 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
: :::.::::.::::: :: ::. : :
CCDS14 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE6 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
CCDS14 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
90 100 110 120 130
140 150 160 170 180 190
pF1KE6 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
CCDS14 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE6 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
CCDS14 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE6 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
CCDS14 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE6 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .::.. :..:
CCDS14 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
320 330 340 350 360 370
380
pF1KE6 IGHLQTKGS
: :..
CCDS14 IRHIRVINGRAVEA
380 390
>>CCDS44019.1 IDH3G gene_id:3421|Hs108|chrX (380 aa)
initn: 993 init1: 965 opt: 1115 Z-score: 1381.3 bits: 264.3 E(32554): 1.3e-70
Smith-Waterman score: 1115; 55.9% identity (78.3% similar) in 313 aa overlap (47-359:53-362)
20 30 40 50 60 70
pF1KE6 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
: :::.::::.::::: :: ::. : :
CCDS44 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE6 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
CCDS44 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
90 100 110 120 130
140 150 160 170 180 190
pF1KE6 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
CCDS44 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE6 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
CCDS44 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE6 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
CCDS44 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE6 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
.::::::: ::.. :: ::.:. ... : :: . .::
CCDS44 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENVRFPSHPTLLPRPVSPCSL
320 330 340 350 360 370
380
pF1KE6 IGHLQTKGS
CCDS44 L
380
>>CCDS10297.1 IDH3A gene_id:3419|Hs108|chr15 (366 aa)
initn: 935 init1: 768 opt: 941 Z-score: 1166.2 bits: 224.5 E(32554): 1.2e-58
Smith-Waterman score: 941; 45.0% identity (75.4% similar) in 333 aa overlap (47-376:30-358)
20 30 40 50 60 70
pF1KE6 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
: ::..::::.:::. :: ..: :: .
CCDS10 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
10 20 30 40 50
80 90 100 110 120 130
pF1KE6 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
CCDS10 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE6 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
CCDS10 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
CCDS10 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE6 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
CCDS10 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE6 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFI
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: . .::
CCDS10 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
300 310 320 330 340 350
380
pF1KE6 KSVIGHLQTKGS
. .
CCDS10 EEICRRVKDLD
360
385 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:14:20 2016 done: Tue Nov 8 12:14:20 2016
Total Scan time: 2.140 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]