Result of FASTA (omim) for
pFN21AE6334
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6334, 316 aa
1>>>pF1KE6334 316 - 316 aa - 316 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8155+/-0.000351; mu= 18.7209+/- 0.022
mean_var=66.8067+/-13.445, 0's: 0 Z-trim(113.8): 31 B-trim: 0 in 0/55
Lambda= 0.156915
statistics sampled from 23279 (23308) to 23279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.273), width: 16
Scan time: 7.170
The best scores are: opt bits E(85289)
NP_009014 (OMIM: 606261) nucleoside diphosphate-li ( 316) 2164 498.7 6.5e-141
NP_932158 (OMIM: 606261) nucleoside diphosphate-li ( 147) 1000 234.9 7.6e-62
NP_694853 (OMIM: 300527) diphosphoinositol polypho ( 164) 162 45.2 0.00011
NP_001291892 (OMIM: 300527) diphosphoinositol poly ( 164) 162 45.2 0.00011
NP_950241 (OMIM: 609229) diphosphoinositol polypho ( 181) 161 45.1 0.00013
NP_061967 (OMIM: 609229) diphosphoinositol polypho ( 180) 152 43.0 0.00055
NP_060629 (OMIM: 300528) diphosphoinositol polypho ( 164) 151 42.8 0.0006
NP_006694 (OMIM: 609228) diphosphoinositol polypho ( 172) 143 41.0 0.0022
>>NP_009014 (OMIM: 606261) nucleoside diphosphate-linked (316 aa)
initn: 2164 init1: 2164 opt: 2164 Z-score: 2650.9 bits: 498.7 E(85289): 6.5e-141
Smith-Waterman score: 2164; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE6 MRQPLSWGRWRAMLARTYGPGPSAGYRWASGAQGYVRNPPVGACDLQGELDRFGGISVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MRQPLSWGRWRAMLARTYGPGPSAGYRWASGAQGYVRNPPVGACDLQGELDRFGGISVRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ARLDALDRLDAAAFQKGLQAAVQQWRSEGRTAVWLHIPILQSRFIAPAASLGFCFHHAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ARLDALDRLDAAAFQKGLQAAVQQWRSEGRTAVWLHIPILQSRFIAPAASLGFCFHHAES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DSSTLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DSSTLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 EEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 EECLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EECLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKL
250 260 270 280 290 300
310
pF1KE6 YHKELPENYKTMKGID
::::::::::::::::
NP_009 YHKELPENYKTMKGID
310
>>NP_932158 (OMIM: 606261) nucleoside diphosphate-linked (147 aa)
initn: 1000 init1: 1000 opt: 1000 Z-score: 1231.3 bits: 234.9 E(85289): 7.6e-62
Smith-Waterman score: 1000; 100.0% identity (100.0% similar) in 147 aa overlap (170-316:1-147)
140 150 160 170 180 190
pF1KE6 ASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEEDIGDTAVREVFEETGIK
::::::::::::::::::::::::::::::
NP_932 MWKFPGGLSEPEEDIGDTAVREVFEETGIK
10 20 30
200 210 220 230 240 250
pF1KE6 SEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEECLRCEWMDLNDLAKTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 SEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEECLRCEWMDLNDLAKTEN
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE6 TTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLYHKELPENYKTMKGID
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 TTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLYHKELPENYKTMKGID
100 110 120 130 140
>>NP_694853 (OMIM: 300527) diphosphoinositol polyphospha (164 aa)
initn: 142 init1: 142 opt: 162 Z-score: 205.4 bits: 45.2 E(85289): 0.00011
Smith-Waterman score: 162; 26.2% identity (61.9% similar) in 126 aa overlap (153-274:28-146)
130 140 150 160 170 180
pF1KE6 STLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEE
: ..:.:.. .. . : ::: ::::
NP_694 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSS-SRYPDRWIVPGGGMEPEE
10 20 30 40 50
190 200 210 220 230
pF1KE6 DIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICR---LKPYSFTINFC
. : .:::::.::.:.:... .:.. .:. .: .. .:.. :. . ....
NP_694 EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPK--HRTYVYVLTVTELLEDWEDSVSIG
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE6 QEECLRCEWMDLNDLAKT-ENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFY
... ::. ..: :. . :. .. . : :
NP_694 RKR----EWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
120 130 140 150 160
300 310
pF1KE6 KLYHKELPENYKTMKGID
>>NP_001291892 (OMIM: 300527) diphosphoinositol polyphos (164 aa)
initn: 142 init1: 142 opt: 162 Z-score: 205.4 bits: 45.2 E(85289): 0.00011
Smith-Waterman score: 162; 26.2% identity (61.9% similar) in 126 aa overlap (153-274:28-146)
130 140 150 160 170 180
pF1KE6 STLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEE
: ..:.:.. .. . : ::: ::::
NP_001 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSS-SRYPDRWIVPGGGMEPEE
10 20 30 40 50
190 200 210 220 230
pF1KE6 DIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICR---LKPYSFTINFC
. : .:::::.::.:.:... .:.. .:. .: .. .:.. :. . ....
NP_001 EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPK--HRTYVYVLTVTELLEDWEDSVSIG
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE6 QEECLRCEWMDLNDLAKT-ENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFY
... ::. ..: :. . :. .. . : :
NP_001 RKR----EWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
120 130 140 150 160
300 310
pF1KE6 KLYHKELPENYKTMKGID
>>NP_950241 (OMIM: 609229) diphosphoinositol polyphospha (181 aa)
initn: 133 init1: 133 opt: 161 Z-score: 203.6 bits: 45.1 E(85289): 0.00013
Smith-Waterman score: 161; 27.8% identity (61.9% similar) in 126 aa overlap (153-274:29-147)
130 140 150 160 170 180
pF1KE6 STLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEE
:. ..:.:.. .. ..: ::: ::::
NP_950 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSS-SRYPDQWIVPGGGMEPEE
10 20 30 40 50
190 200 210 220 230
pF1KE6 DIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICR---LKPYSFTINFC
. : .:::::.::.:.:... .:.: .: : .. .:.. :. . ..:.
NP_950 EPGGAAVREVYEEAGVKGKLGRLLGIFEQ--NQDRKHRTYVYVLTVTEILEDWEDSVNIG
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE6 QEECLRCEWMDLNDLAKT-ENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFY
... ::. ..: :. . :. .. . : :
NP_950 RKR----EWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAA
120 130 140 150 160 170
300 310
pF1KE6 KLYHKELPENYKTMKGID
NP_950 QTSGLPSSVR
180
>>NP_061967 (OMIM: 609229) diphosphoinositol polyphospha (180 aa)
initn: 125 init1: 125 opt: 152 Z-score: 192.6 bits: 43.0 E(85289): 0.00055
Smith-Waterman score: 152; 27.0% identity (61.1% similar) in 126 aa overlap (153-274:29-146)
130 140 150 160 170 180
pF1KE6 STLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEE
:. ..:.:.. .. ..: ::: ::::
NP_061 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSS-SRYPDQWIVPGGGMEPEE
10 20 30 40 50
190 200 210 220 230
pF1KE6 DIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICR---LKPYSFTINFC
. : .:::::.::.:.:... .:.: . : .. .:.. :. . ..:.
NP_061 EPGGAAVREVYEEAGVKGKLGRLLGIFE---NQDRKHRTYVYVLTVTEILEDWEDSVNIG
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE6 QEECLRCEWMDLNDLAKT-ENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFY
... ::. ..: :. . :. .. . : :
NP_061 RKR----EWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAA
120 130 140 150 160 170
300 310
pF1KE6 KLYHKELPENYKTMKGID
NP_061 QTSGLPSSVR
180
>>NP_060629 (OMIM: 300528) diphosphoinositol polyphospha (164 aa)
initn: 132 init1: 132 opt: 151 Z-score: 191.9 bits: 42.8 E(85289): 0.0006
Smith-Waterman score: 151; 37.1% identity (72.6% similar) in 62 aa overlap (153-214:28-88)
130 140 150 160 170 180
pF1KE6 STLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEE
: ..:.:.. .. . : ::: ::::
NP_060 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSS-SRYPDRWIVPGGGMEPEE
10 20 30 40 50
190 200 210 220 230 240
pF1KE6 DIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEE
. : .:::::.::.:.:... .:.. .:. .
NP_060 EPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRK
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE6 CLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLYH
NP_060 REWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
120 130 140 150 160
>>NP_006694 (OMIM: 609228) diphosphoinositol polyphospha (172 aa)
initn: 157 init1: 102 opt: 143 Z-score: 181.8 bits: 41.0 E(85289): 0.0022
Smith-Waterman score: 143; 25.8% identity (58.1% similar) in 124 aa overlap (153-275:29-147)
130 140 150 160 170 180
pF1KE6 STLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEE
:: ...:.:.. .. . : ::: ::::
NP_006 MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSS-SRHPDRWIVPGGGMEPEE
10 20 30 40 50
190 200 210 220 230 240
pF1KE6 DIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEE
. . .::::: ::.:.:. . ...: ... . . :. . ..:. ...
NP_006 EPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKR
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE6 CLRCEWMDLNDLAKT-ENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLY
::. ..: :. . :. . . : ::
NP_006 ----EWFKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMSGIR
120 130 140 150 160 170
310
pF1KE6 HKELPENYKTMKGID
316 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:12:36 2016 done: Tue Nov 8 12:12:37 2016
Total Scan time: 7.170 Total Display time: -0.040
Function used was FASTA [36.3.4 Apr, 2011]