Result of FASTA (omim) for
pFN21AE6323
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6323, 440 aa
1>>>pF1KE6323 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4711+/-0.000436; mu= 11.6791+/- 0.027
mean_var=104.2013+/-21.110, 0's: 0 Z-trim(112.8): 115 B-trim: 0 in 0/51
Lambda= 0.125643
statistics sampled from 21706 (21849) to 21706 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.256), width: 16
Scan time: 6.700
The best scores are: opt bits E(85289)
NP_116028 (OMIM: 608639) pleckstrin homology domai ( 440) 2888 534.6 1.9e-151
XP_005249954 (OMIM: 608639) PREDICTED: pleckstrin ( 459) 2848 527.4 3.1e-149
XP_011513896 (OMIM: 608639) PREDICTED: pleckstrin ( 455) 2847 527.2 3.4e-149
NP_001183956 (OMIM: 608639) pleckstrin homology do ( 459) 2847 527.2 3.5e-149
XP_011513894 (OMIM: 608639) PREDICTED: pleckstrin ( 475) 2847 527.2 3.6e-149
XP_016868233 (OMIM: 608639) PREDICTED: pleckstrin ( 491) 2847 527.2 3.7e-149
XP_011513893 (OMIM: 608639) PREDICTED: pleckstrin ( 491) 2847 527.2 3.7e-149
XP_016868234 (OMIM: 608639) PREDICTED: pleckstrin ( 441) 2846 527.0 3.8e-149
NP_001183955 (OMIM: 608639) pleckstrin homology do ( 519) 2847 527.2 3.8e-149
XP_011513897 (OMIM: 608639) PREDICTED: pleckstrin ( 439) 2841 526.1 7.1e-149
XP_016868237 (OMIM: 608639) PREDICTED: pleckstrin ( 290) 1709 320.8 3e-87
XP_011513898 (OMIM: 608639) PREDICTED: pleckstrin ( 350) 1708 320.6 3.9e-87
XP_016868238 (OMIM: 608639) PREDICTED: pleckstrin ( 260) 1520 286.5 5.6e-77
XP_016868235 (OMIM: 608639) PREDICTED: pleckstrin ( 320) 1519 286.4 7.5e-77
XP_016868236 (OMIM: 608639) PREDICTED: pleckstrin ( 320) 1519 286.4 7.5e-77
NP_061964 (OMIM: 607774) pleckstrin homology domai ( 300) 843 163.8 5.5e-40
XP_011509991 (OMIM: 607774) PREDICTED: pleckstrin ( 240) 499 101.4 2.7e-21
NP_683706 (OMIM: 606737) oxysterol-binding protein ( 723) 290 63.8 1.7e-09
NP_002547 (OMIM: 167040) oxysterol-binding protein ( 807) 273 60.8 1.6e-08
NP_078862 (OMIM: 606737) oxysterol-binding protein ( 736) 270 60.2 2.1e-08
NP_057517 (OMIM: 608949) glycolipid transfer prote ( 209) 255 57.1 5e-08
XP_016855707 (OMIM: 606737) PREDICTED: oxysterol-b ( 713) 254 57.3 1.5e-07
NP_112729 (OMIM: 604677,616351) collagen type IV a ( 598) 252 56.9 1.7e-07
XP_016864408 (OMIM: 604677,616351) PREDICTED: coll ( 598) 252 56.9 1.7e-07
XP_011541393 (OMIM: 604677,616351) PREDICTED: coll ( 605) 252 56.9 1.7e-07
NP_005704 (OMIM: 604677,616351) collagen type IV a ( 624) 252 56.9 1.8e-07
XP_006714576 (OMIM: 604677,616351) PREDICTED: coll ( 624) 252 56.9 1.8e-07
XP_011541392 (OMIM: 604677,616351) PREDICTED: coll ( 631) 252 56.9 1.8e-07
NP_001123577 (OMIM: 604677,616351) collagen type I ( 752) 252 56.9 2.1e-07
XP_006710381 (OMIM: 606737) PREDICTED: oxysterol-b ( 726) 245 55.6 4.8e-07
XP_016884198 (OMIM: 606729) PREDICTED: oxysterol-b ( 818) 243 55.3 6.8e-07
XP_011528361 (OMIM: 606729) PREDICTED: oxysterol-b ( 819) 243 55.3 6.8e-07
XP_006724266 (OMIM: 606729) PREDICTED: oxysterol-b ( 866) 243 55.3 7.2e-07
XP_016884197 (OMIM: 606729) PREDICTED: oxysterol-b ( 867) 243 55.3 7.2e-07
XP_005261522 (OMIM: 606729) PREDICTED: oxysterol-b ( 874) 243 55.3 7.2e-07
XP_011528360 (OMIM: 606729) PREDICTED: oxysterol-b ( 905) 243 55.3 7.4e-07
XP_011528359 (OMIM: 606729) PREDICTED: oxysterol-b ( 906) 243 55.3 7.4e-07
NP_001269668 (OMIM: 606729) oxysterol-binding prot ( 915) 243 55.3 7.5e-07
NP_110385 (OMIM: 606729) oxysterol-binding protein ( 916) 243 55.3 7.5e-07
XP_011538903 (OMIM: 606737) PREDICTED: oxysterol-b ( 736) 218 50.8 1.5e-05
NP_683707 (OMIM: 606737) oxysterol-binding protein ( 746) 218 50.8 1.5e-05
XP_011538902 (OMIM: 606737) PREDICTED: oxysterol-b ( 749) 218 50.8 1.5e-05
XP_011538901 (OMIM: 606737) PREDICTED: oxysterol-b ( 759) 218 50.8 1.5e-05
XP_011536736 (OMIM: 608949) PREDICTED: glycolipid ( 168) 167 41.1 0.0026
>>NP_116028 (OMIM: 608639) pleckstrin homology domain-co (440 aa)
initn: 2888 init1: 2888 opt: 2888 Z-score: 2839.8 bits: 534.6 E(85289): 1.9e-151
Smith-Waterman score: 2888; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::::::::::
NP_116 EVKNGEKDIQTALRNPTENT
430 440
>>XP_005249954 (OMIM: 608639) PREDICTED: pleckstrin homo (459 aa)
initn: 2848 init1: 2848 opt: 2848 Z-score: 2800.3 bits: 527.4 E(85289): 3.1e-149
Smith-Waterman score: 2848; 100.0% identity (100.0% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::::
XP_005 EVKNGEKDIQTALRTHKCLMVAQEGCHSESGGCRVACRT
430 440 450
>>XP_011513896 (OMIM: 608639) PREDICTED: pleckstrin homo (455 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2799.4 bits: 527.2 E(85289): 3.4e-149
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
XP_011 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAV
430 440 450
>>NP_001183956 (OMIM: 608639) pleckstrin homology domain (459 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2799.3 bits: 527.2 E(85289): 3.5e-149
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
NP_001 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAGHTNV
430 440 450
>>XP_011513894 (OMIM: 608639) PREDICTED: pleckstrin homo (475 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2799.1 bits: 527.2 E(85289): 3.6e-149
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
XP_011 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAEIQQKTLDTKTYPDEDPELQE
430 440 450 460 470
>>XP_016868233 (OMIM: 608639) PREDICTED: pleckstrin homo (491 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2798.9 bits: 527.2 E(85289): 3.7e-149
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
XP_016 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAVLDQMKLQTAHPYLQYTLNNHNGYHV
430 440 450 460 470 480
>>XP_011513893 (OMIM: 608639) PREDICTED: pleckstrin homo (491 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2798.9 bits: 527.2 E(85289): 3.7e-149
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
XP_011 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAVLDQMKLQTAHPYLQYTLNNHNGYHV
430 440 450 460 470 480
>>XP_016868234 (OMIM: 608639) PREDICTED: pleckstrin homo (441 aa)
initn: 2899 init1: 2846 opt: 2846 Z-score: 2798.6 bits: 527.0 E(85289): 3.8e-149
Smith-Waterman score: 2846; 98.9% identity (99.5% similar) in 439 aa overlap (1-439:1-439)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: . .:.
XP_016 EVKNGEKDIQTALSGRSESLT
430 440
>>NP_001183955 (OMIM: 608639) pleckstrin homology domain (519 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2798.6 bits: 527.2 E(85289): 3.8e-149
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
NP_001 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTVKEGDHQKE
430 440 450 460 470 480
>>XP_011513897 (OMIM: 608639) PREDICTED: pleckstrin homo (439 aa)
initn: 2841 init1: 2841 opt: 2841 Z-score: 2793.7 bits: 526.1 E(85289): 7.1e-149
Smith-Waterman score: 2841; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
:::::::::::::
XP_011 EVKNGEKDIQTALSVGMWV
430
440 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:06:03 2016 done: Tue Nov 8 12:06:04 2016
Total Scan time: 6.700 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]