Result of FASTA (omim) for
pFN21AE6312
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6312, 314 aa
1>>>pF1KE6312 314 - 314 aa - 314 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8403+/-0.000418; mu= 17.9020+/- 0.026
mean_var=65.1361+/-13.685, 0's: 0 Z-trim(111.1): 255 B-trim: 1191 in 1/50
Lambda= 0.158914
statistics sampled from 19240 (19563) to 19240 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.229), width: 16
Scan time: 4.810
The best scores are: opt bits E(85289)
NP_003553 (OMIM: 604165) mitochondrial 2-oxoglutar ( 314) 2034 475.4 6.6e-134
NP_001158889 (OMIM: 604165) mitochondrial 2-oxoglu ( 303) 1827 427.9 1.2e-119
NP_001158890 (OMIM: 604165) mitochondrial 2-oxoglu ( 263) 1520 357.5 1.7e-98
NP_036272 (OMIM: 606794) mitochondrial dicarboxyla ( 287) 663 161.0 2.6e-39
NP_001269127 (OMIM: 300242) brain mitochondrial ca ( 290) 641 156.0 8.5e-38
NP_001269125 (OMIM: 300242) brain mitochondrial ca ( 322) 641 156.0 9.3e-38
NP_001269124 (OMIM: 300242) brain mitochondrial ca ( 325) 641 156.0 9.3e-38
XP_011529704 (OMIM: 300242) PREDICTED: brain mitoc ( 334) 641 156.0 9.5e-38
XP_016885425 (OMIM: 300242) PREDICTED: brain mitoc ( 306) 616 150.3 4.7e-36
XP_016885428 (OMIM: 300242) PREDICTED: brain mitoc ( 338) 616 150.3 5.1e-36
XP_016885427 (OMIM: 300242) PREDICTED: brain mitoc ( 341) 616 150.3 5.1e-36
XP_016885426 (OMIM: 300242) PREDICTED: brain mitoc ( 350) 616 150.3 5.2e-36
NP_001257817 (OMIM: 606794) mitochondrial dicarbox ( 296) 608 148.4 1.6e-35
XP_016879709 (OMIM: 606794) PREDICTED: mitochondri ( 244) 595 145.4 1.1e-34
NP_068605 (OMIM: 113730,601665) mitochondrial brow ( 307) 586 143.4 5.6e-34
NP_001010875 (OMIM: 610793) kidney mitochondrial c ( 291) 577 141.3 2.2e-33
XP_016876013 (OMIM: 610793) PREDICTED: kidney mito ( 291) 577 141.3 2.2e-33
XP_005263263 (OMIM: 113730,601665) PREDICTED: mito ( 306) 575 140.9 3.2e-33
NP_003347 (OMIM: 601665,602044) mitochondrial unco ( 312) 571 140.0 6.1e-33
NP_997231 (OMIM: 610817) solute carrier family 25 ( 304) 537 132.2 1.3e-30
NP_003346 (OMIM: 601693,607447) mitochondrial unco ( 309) 537 132.2 1.3e-30
XP_011530530 (OMIM: 113730,601665) PREDICTED: mito ( 277) 531 130.8 3.2e-30
NP_073714 (OMIM: 601665,602044) mitochondrial unco ( 275) 493 122.0 1.3e-27
XP_005262546 (OMIM: 300242) PREDICTED: brain mitoc ( 224) 491 121.5 1.6e-27
NP_001273735 (OMIM: 610793) kidney mitochondrial c ( 240) 487 120.6 3.1e-27
XP_016885429 (OMIM: 300242) PREDICTED: brain mitoc ( 240) 466 115.8 8.8e-26
XP_005266378 (OMIM: 610793) PREDICTED: kidney mito ( 293) 464 115.4 1.4e-25
XP_006719857 (OMIM: 610793) PREDICTED: kidney mito ( 293) 464 115.4 1.4e-25
XP_016876012 (OMIM: 610793) PREDICTED: kidney mito ( 293) 464 115.4 1.4e-25
XP_006719856 (OMIM: 610793) PREDICTED: kidney mito ( 293) 464 115.4 1.4e-25
XP_005266379 (OMIM: 610793) PREDICTED: kidney mito ( 254) 458 114.0 3.3e-25
NP_001307799 (OMIM: 610818) solute carrier family ( 300) 448 111.8 1.8e-24
NP_004268 (OMIM: 613725) mitochondrial uncoupling ( 323) 447 111.6 2.3e-24
NP_001190980 (OMIM: 613725) mitochondrial uncoupli ( 300) 430 107.6 3.2e-23
XP_005249540 (OMIM: 613725) PREDICTED: mitochondri ( 310) 430 107.6 3.3e-23
NP_001273736 (OMIM: 610793) kidney mitochondrial c ( 216) 420 105.2 1.2e-22
XP_011533329 (OMIM: 610793) PREDICTED: kidney mito ( 216) 420 105.2 1.2e-22
XP_011522148 (OMIM: 610818) PREDICTED: solute carr ( 291) 412 103.5 5.5e-22
NP_001307801 (OMIM: 610818) solute carrier family ( 295) 412 103.5 5.5e-22
NP_958928 (OMIM: 610818) solute carrier family 25 ( 295) 412 103.5 5.5e-22
NP_001307800 (OMIM: 610818) solute carrier family ( 295) 412 103.5 5.5e-22
XP_016885430 (OMIM: 300242) PREDICTED: brain mitoc ( 197) 405 101.8 1.2e-21
XP_016885431 (OMIM: 300242) PREDICTED: brain mitoc ( 197) 405 101.8 1.2e-21
XP_011539595 (OMIM: 610817) PREDICTED: solute carr ( 251) 399 100.5 3.8e-21
XP_011539594 (OMIM: 610817) PREDICTED: solute carr ( 256) 399 100.5 3.9e-21
NP_001257882 (OMIM: 606794) mitochondrial dicarbox ( 406) 392 99.0 1.7e-20
XP_016885432 (OMIM: 300242) PREDICTED: brain mitoc ( 157) 387 97.6 1.8e-20
XP_016867001 (OMIM: 613725) PREDICTED: mitochondri ( 195) 364 92.4 8.2e-19
NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 352 89.7 7.7e-18
NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 352 89.7 7.7e-18
>>NP_003553 (OMIM: 604165) mitochondrial 2-oxoglutarate/ (314 aa)
initn: 2034 init1: 2034 opt: 2034 Z-score: 2525.0 bits: 475.4 E(85289): 6.6e-134
Smith-Waterman score: 2034; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
250 260 270 280 290 300
310
pF1KE6 EQMNKAYKRLFLSG
::::::::::::::
NP_003 EQMNKAYKRLFLSG
310
>>NP_001158889 (OMIM: 604165) mitochondrial 2-oxoglutara (303 aa)
initn: 1949 init1: 1827 opt: 1827 Z-score: 2268.8 bits: 427.9 E(85289): 1.2e-119
Smith-Waterman score: 1931; 96.5% identity (96.5% similar) in 314 aa overlap (1-314:1-303)
10 20 30 40 50 60
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTRE
::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 MAATASAGAGGIDGKPRTSPK-----------MGATVFVQPLDLVKNRMQLSGEGAKTRE
10 20 30 40
70 80 90 100 110 120
pF1KE6 YKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
230 240 250 260 270 280
310
pF1KE6 EQMNKAYKRLFLSG
::::::::::::::
NP_001 EQMNKAYKRLFLSG
290 300
>>NP_001158890 (OMIM: 604165) mitochondrial 2-oxoglutara (263 aa)
initn: 1520 init1: 1520 opt: 1520 Z-score: 1889.2 bits: 357.5 E(85289): 1.7e-98
Smith-Waterman score: 1601; 83.8% identity (83.8% similar) in 314 aa overlap (1-314:1-263)
10 20 30 40 50 60
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTRE
::::::::::::::::::::::::::::::::
NP_001 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAG----------------------------
10 20 30
70 80 90 100 110 120
pF1KE6 YKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
:::::::::::::::::::::::::::::::::::::
NP_001 -----------------------LSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
40 50 60
130 140 150 160 170 180
pF1KE6 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE6 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE6 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
190 200 210 220 230 240
310
pF1KE6 EQMNKAYKRLFLSG
::::::::::::::
NP_001 EQMNKAYKRLFLSG
250 260
>>NP_036272 (OMIM: 606794) mitochondrial dicarboxylate c (287 aa)
initn: 686 init1: 459 opt: 663 Z-score: 826.8 bits: 161.0 E(85289): 2.6e-39
Smith-Waterman score: 663; 39.4% identity (73.2% similar) in 284 aa overlap (24-307:9-281)
10 20 30 40 50 60
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTRE
.. :::::. ::. ..::::.: ..: . : .: :
NP_036 MAAEARVSRWYFGGLASCGAACCTHPLDLLKVHLQTQQE-VKLR-
10 20 30 40
70 80 90 100 110 120
pF1KE6 YKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFL
. :: .....:. ..:.::::.: :: ::. ::..:: .. .:.. .. : :
NP_036 --MTGMALR-VVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTL
:...: ..: .:.::::::... .:: : .:: :::.: .....: :..::::. :
NP_036 EKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 WRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPV
. : . .:...:...::. :.:.::..:..::.::::. :: ::.:.: .: .:.
NP_036 FSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 DIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFL
:. :::..: .: ::.. . .... : ....::..: :: :::::::.::
NP_036 DVLKTRLMN-----SKGEYQGVFHCAVETAKL-GPLAFYKGLVPAGIRLIPHTVLTFVFL
230 240 250 260 270
310
pF1KE6 EQMNKAYKRLFLSG
::. : .
NP_036 EQLRKNFGIKVPS
280
>>NP_001269127 (OMIM: 300242) brain mitochondrial carrie (290 aa)
initn: 575 init1: 237 opt: 641 Z-score: 799.5 bits: 156.0 E(85289): 8.5e-38
Smith-Waterman score: 641; 38.1% identity (71.3% similar) in 286 aa overlap (25-305:9-287)
10 20 30 40 50
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTR-
:..::::.. : . :.::.:.:.:..:.. .:
NP_001 MSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARF
10 20 30 40
60 70 80 90 100 110
pF1KE6 ---EYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTP
.:. :::: : : ::. ..:.:.. .:::::.: : ..::: : .::
NP_001 KEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSL-KRLFVERLED
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 PGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEG
.:.. . :...:. .. ...:..: ::: :.: : .: ......: : ..::
NP_001 ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL----FQG--SMIGSFIDIYQQEG
110 120 130 140 150
180 190 200 210 220 230
pF1KE6 VLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAA
. :::: .:: ::..: ...: :. .:. :. ::...:.:: :: .:. ::. . :
NP_001 TRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE6 SMPVDIAKTRIQNMRMIDGKPE-YKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVL
: :::...::..:.: : :. . ::. .: ..:. ..::::.:.::: : . :::: ...
NP_001 SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNII
220 230 240 250 260 270
300 310
pF1KE6 TFIFLEQMNKAYKRLFLSG
:: ::...
NP_001 FFITYEQLKRLQI
280 290
>>NP_001269125 (OMIM: 300242) brain mitochondrial carrie (322 aa)
initn: 575 init1: 237 opt: 641 Z-score: 798.9 bits: 156.0 E(85289): 9.3e-38
Smith-Waterman score: 645; 36.9% identity (69.6% similar) in 309 aa overlap (2-305:26-319)
10 20 30
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGAT
..:.: .:.. :: :..::::.. :
NP_001 MGIFPGIILIFLRVKFATAAVIHQKSTTVSHEMSGLNWKP--------FVYGGLASIVAE
10 20 30 40 50
40 50 60 70 80 90
pF1KE6 VFVQPLDLVKNRMQLSGEGAKTR----EYKTSFHALTSILKAEGLRGIYTGLSAGLLRQA
. :.::.:.:.:..:.. .: .:. :::: : : ::. ..:.:.. .:::::
NP_001 FGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQA
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE6 TYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGR
.: : ..::: : .:: .:.. . :...:. .. ...:..: ::: :.:
NP_001 SYGTIKIGIYQSL-KRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE6 LPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDS
: .: ......: : ..::. :::: .:: ::..: ...: :. .:. :. :
NP_001 L----FQG--SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILS
180 190 200 210 220
220 230 240 250 260 270
pF1KE6 GYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPE-YKNGLDVLFKVVR
:...:.:: :: .:. ::. . :: :::...::..:.: : :. . ::. .: ..:. .
NP_001 GMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWK
230 240 250 260 270 280
280 290 300 310
pF1KE6 YEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
.::::.:.::: : . :::: ... :: ::...
NP_001 HEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI
290 300 310 320
>>NP_001269124 (OMIM: 300242) brain mitochondrial carrie (325 aa)
initn: 575 init1: 237 opt: 641 Z-score: 798.8 bits: 156.0 E(85289): 9.3e-38
Smith-Waterman score: 645; 36.9% identity (69.6% similar) in 309 aa overlap (2-305:29-322)
10 20 30
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGM
..:.: .:.. :: :..::::..
NP_001 MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKP--------FVYGGLASI
10 20 30 40 50
40 50 60 70 80
pF1KE6 GATVFVQPLDLVKNRMQLSGEGAKTR----EYKTSFHALTSILKAEGLRGIYTGLSAGLL
: . :.::.:.:.:..:.. .: .:. :::: : : ::. ..:.:.. .::
NP_001 VAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALL
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE6 RQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTA
:::.: : ..::: : .:: .:.. . :...:. .. ...:..: ::: :
NP_001 RQASYGTIKIGIYQSL-KRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQA
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE6 DGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFL
.: : .: ......: : ..::. :::: .:: ::..: ...: :. .:. :
NP_001 QGSL----FQG--SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHL
180 190 200 210 220
210 220 230 240 250 260
pF1KE6 LDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPE-YKNGLDVLFK
. ::...:.:: :: .:. ::. . :: :::...::..:.: : :. . ::. .: ..:
NP_001 ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILK
230 240 250 260 270 280
270 280 290 300 310
pF1KE6 VVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
. ..::::.:.::: : . :::: ... :: ::...
NP_001 MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI
290 300 310 320
>>XP_011529704 (OMIM: 300242) PREDICTED: brain mitochond (334 aa)
initn: 575 init1: 237 opt: 641 Z-score: 798.7 bits: 156.0 E(85289): 9.5e-38
Smith-Waterman score: 645; 36.9% identity (69.6% similar) in 309 aa overlap (2-305:38-331)
10 20 30
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLA
..:.: .:.. :: :..::::
XP_011 ILIFLRVKFATAAVIVSGVSKHLHCISHQKSTTVSHEMSGLNWKP--------FVYGGLA
10 20 30 40 50
40 50 60 70 80
pF1KE6 GMGATVFVQPLDLVKNRMQLSGEGAKTR----EYKTSFHALTSILKAEGLRGIYTGLSAG
.. : . :.::.:.:.:..:.. .: .:. :::: : : ::. ..:.:.. .
XP_011 SIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPA
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE6 LLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRM
:::::.: : ..::: : .:: .:.. . :...:. .. ...:..: :::
XP_011 LLRQASYGTIKIGIYQSL-KRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRM
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE6 TADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQ
:.: : .: ......: : ..::. :::: .:: ::..: ...: :. .:.
XP_011 QAQGSL----FQG--SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE6 FLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPE-YKNGLDVL
:. ::...:.:: :: .:. ::. . :: :::...::..:.: : :. . ::. .: .
XP_011 HLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGI
240 250 260 270 280 290
270 280 290 300 310
pF1KE6 FKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
.:. ..::::.:.::: : . :::: ... :: ::...
XP_011 LKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI
300 310 320 330
>>XP_016885425 (OMIM: 300242) PREDICTED: brain mitochond (306 aa)
initn: 548 init1: 237 opt: 616 Z-score: 768.2 bits: 150.3 E(85289): 4.7e-36
Smith-Waterman score: 616; 37.7% identity (71.1% similar) in 284 aa overlap (25-303:9-283)
10 20 30 40 50
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTR-
:..::::.. : . :.::.:.:.:..:.. .:
XP_016 MSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARF
10 20 30 40
60 70 80 90 100 110
pF1KE6 ---EYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTP
.:. :::: : : ::. ..:.:.. .:::::.: : ..::: : .::
XP_016 KEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSL-KRLFVERLED
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 PGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEG
.:.. . :...:. .. ...:..: ::: :.: : .: ......: : ..::
XP_016 ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL----FQG--SMIGSFIDIYQQEG
110 120 130 140 150
180 190 200 210 220 230
pF1KE6 VLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAA
. :::: .:: ::..: ...: :. .:. :. ::...:.:: :: .:. ::. . :
XP_016 TRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE6 SMPVDIAKTRIQNMRMIDGKPE-YKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVL
: :::...::..:.: : :. . ::. .: ..:. ..::::.:.::: : . :::: ...
XP_016 SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNII
220 230 240 250 260 270
300 310
pF1KE6 TFIFLEQMNKAYKRLFLSG
. .:.:
XP_016 --VSFERMKASASSSQIILGYGKENLIIKAF
280 290 300
>>XP_016885428 (OMIM: 300242) PREDICTED: brain mitochond (338 aa)
initn: 548 init1: 237 opt: 616 Z-score: 767.6 bits: 150.3 E(85289): 5.1e-36
Smith-Waterman score: 620; 36.5% identity (69.4% similar) in 307 aa overlap (2-303:26-315)
10 20 30
pF1KE6 MAATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGAT
..:.: .:.. :: :..::::.. :
XP_016 MGIFPGIILIFLRVKFATAAVIHQKSTTVSHEMSGLNWKP--------FVYGGLASIVAE
10 20 30 40 50
40 50 60 70 80 90
pF1KE6 VFVQPLDLVKNRMQLSGEGAKTR----EYKTSFHALTSILKAEGLRGIYTGLSAGLLRQA
. :.::.:.:.:..:.. .: .:. :::: : : ::. ..:.:.. .:::::
XP_016 FGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQA
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE6 TYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGR
.: : ..::: : .:: .:.. . :...:. .. ...:..: ::: :.:
XP_016 SYGTIKIGIYQSL-KRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE6 LPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDS
: .: ......: : ..::. :::: .:: ::..: ...: :. .:. :. :
XP_016 L----FQG--SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILS
180 190 200 210 220
220 230 240 250 260 270
pF1KE6 GYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPE-YKNGLDVLFKVVR
:...:.:: :: .:. ::. . :: :::...::..:.: : :. . ::. .: ..:. .
XP_016 GMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWK
230 240 250 260 270 280
280 290 300 310
pF1KE6 YEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
.::::.:.::: : . :::: ... . .:.:
XP_016 HEGFFALYKGFWPNWLRLGPWNII--VSFERMKASASSSQIILGYGKENLIIKAF
290 300 310 320 330
314 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:59:42 2016 done: Tue Nov 8 11:59:43 2016
Total Scan time: 4.810 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]