Result of FASTA (ccds) for
pFN21AE6306
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6306, 322 aa
1>>>pF1KE6306 322 - 322 aa - 322 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1320+/-0.000888; mu= 16.5375+/- 0.053
mean_var=60.3805+/-12.192, 0's: 0 Z-trim(104.1): 20 B-trim: 0 in 0/52
Lambda= 0.165054
statistics sampled from 7747 (7755) to 7747 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.238), width: 16
Scan time: 2.090
The best scores are: opt bits E(32554)
CCDS7539.1 SFXN2 gene_id:118980|Hs108|chr10 ( 322) 2150 520.5 6.8e-148
CCDS4394.1 SFXN1 gene_id:94081|Hs108|chr5 ( 322) 1192 292.4 3.2e-79
CCDS7508.2 SFXN3 gene_id:81855|Hs108|chr10 ( 325) 1164 285.7 3.3e-77
CCDS1922.1 SFXN5 gene_id:94097|Hs108|chr2 ( 340) 761 189.8 2.6e-48
CCDS82469.1 SFXN5 gene_id:94097|Hs108|chr2 ( 253) 522 132.8 2.8e-31
CCDS7610.1 SFXN4 gene_id:119559|Hs108|chr10 ( 337) 283 76.0 4.8e-14
>>CCDS7539.1 SFXN2 gene_id:118980|Hs108|chr10 (322 aa)
initn: 2150 init1: 2150 opt: 2150 Z-score: 2768.6 bits: 520.5 E(32554): 6.8e-148
Smith-Waterman score: 2150; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322)
10 20 30 40 50 60
pF1KE6 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 WVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 WVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 FAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 ILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 ILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPK
250 260 270 280 290 300
310 320
pF1KE6 LQDTIKAKYGELEPYVYFNKGL
::::::::::::::::::::::
CCDS75 LQDTIKAKYGELEPYVYFNKGL
310 320
>>CCDS4394.1 SFXN1 gene_id:94081|Hs108|chr5 (322 aa)
initn: 1191 init1: 1158 opt: 1192 Z-score: 1535.8 bits: 292.4 E(32554): 3.2e-79
Smith-Waterman score: 1192; 56.1% identity (79.3% similar) in 314 aa overlap (9-322:10-322)
10 20 30 40 50
pF1KE6 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVP
:: ::::: ::.::..::...::::........:. :. .:. :.:.::
CCDS43 MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 PGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFW
:: ..: :: .::::::::::::: .::::: :.: .: ::: :. :::: :::.::
CCDS43 PGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFW
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 QWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWV
::.::::::.::::::.. .: .: ... .: .::: :::::.:.: :::.. ::.::.:
CCDS43 QWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 PFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPG
::::::::::.:::.:::.:: :: : :.: :..:.: :: .:::::.::: :.:::
CCDS43 PFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 MILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEP
: . : ::. ::: :... . ::.:: : : :.: .:. :.::::: . :. ::
CCDS43 MAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEA
250 260 270 280 290 300
300 310 320
pF1KE6 KLQDTIKAKYGELEPYVYFNKGL
.:: :. .. ::. :::::::
CCDS43 ELQAKIQESHPELR-RVYFNKGL
310 320
>>CCDS7508.2 SFXN3 gene_id:81855|Hs108|chr10 (325 aa)
initn: 1161 init1: 1132 opt: 1164 Z-score: 1499.7 bits: 285.7 E(32554): 3.3e-77
Smith-Waterman score: 1164; 56.1% identity (77.7% similar) in 314 aa overlap (9-322:13-325)
10 20 30 40 50
pF1KE6 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMG
::. ::::: :::::..::...::::....: .:. .. .:.. : :
CCDS75 MESKMGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAV
:: :: .:: :: .::::::::::::. .::::: :.: .: ::: :: ::: :.:
CCDS75 VVTPGITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 IFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVG
.:::::::::::.:::.::.. .: .:::.. .: .::: :::::.:.. :::. :::::
CCDS75 VFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLTKHLPPLVG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 RWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMS
:.:::::::::::.:::.:::.:: :: : :. ...:.: :: :: ::::::: :.
CCDS75 RFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 APGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSY
:.: . :.::. ::: :... : ::::: : : :.: .:. :.::::: . .:
CCDS75 IPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISN
250 260 270 280 290 300
300 310 320
pF1KE6 LEPKLQDTIKAKYGELEPYVYFNKGL
:::.:. :. . .: ::.::::
CCDS75 LEPELRAQIHEQNPSVE-VVYYNKGL
310 320
>>CCDS1922.1 SFXN5 gene_id:94097|Hs108|chr2 (340 aa)
initn: 756 init1: 474 opt: 761 Z-score: 980.8 bits: 189.8 E(32554): 2.6e-48
Smith-Waterman score: 761; 39.1% identity (67.6% similar) in 330 aa overlap (3-322:20-340)
10 20 30 40
pF1KE6 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSEREL
.: :.. ::..: .: :: .:::.: ::::.::.::.:
CCDS19 MADTATTASAAAASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 DWAKVMVEKSRMGVVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGM-II
: ..: . :.. ::. ::: :.:. .. .::::.::. . ::: .: : :.
CCDS19 REAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 TGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAV
.:..: .:. ...::::.::: :: :::.::::..:. . .. .:. :. .::. ::
CCDS19 VGLLLP-NQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAV
130 140 150 160 170
170 180 190 200 210
pF1KE6 GMNMLTKKA---PP----LVGRWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIG
:.:.:..:: : :. :.::: :::.:: :. .:: :: .:: : : . : .:
CCDS19 GLNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 HSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFL
:. :: .. .....:... : ..: :..: ::: ..: : :.: .. :.
CCDS19 SSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLV--CLA
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 IF--MVPVACGLFPQKCELPVSYLEPKLQDTIKAKYGELEPYVYFNKGL
: .:.: .:::: :. .: :::.. .. ... : .::::
CCDS19 AFGLALPLAISLFPQMSEIETSQLEPEIAQATSSRT------VVYNKGL
300 310 320 330 340
>>CCDS82469.1 SFXN5 gene_id:94097|Hs108|chr2 (253 aa)
initn: 509 init1: 474 opt: 522 Z-score: 675.1 bits: 132.8 E(32554): 2.8e-31
Smith-Waterman score: 522; 42.2% identity (70.9% similar) in 199 aa overlap (3-193:20-217)
10 20 30 40
pF1KE6 MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSEREL
.: :.. ::..: .: :: .:::.: ::::.::.::.:
CCDS82 MADTATTASAAAASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 DWAKVMVEKSRMGVVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGM-II
: ..: . :.. ::. ::: :.:. .. .::::.::. . ::: .: : :.
CCDS82 REAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 TGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAV
.:..: .:. ...::::.::: :: :::.::::..:. . .. .:. :. .::. ::
CCDS82 VGLLLP-NQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAV
130 140 150 160 170
170 180 190 200 210
pF1KE6 GMNMLTKKA---PP----LVGRWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIG
:.:.:..:: : :. :.::: ::. .: . :
CCDS82 GLNVLVQKANKFTPATRLLIQRFVPFPAVGRLSCRHAPGCSSLCKASCAWQPSAWPCRWP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 HSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFL
CCDS82 SASSRKCQRLKHPN
240 250
>>CCDS7610.1 SFXN4 gene_id:119559|Hs108|chr10 (337 aa)
initn: 220 init1: 144 opt: 283 Z-score: 365.7 bits: 76.0 E(32554): 4.8e-14
Smith-Waterman score: 283; 22.9% identity (56.7% similar) in 319 aa overlap (15-322:32-337)
10 20 30 40
pF1KE6 MEADLSGFNIDAPRW--DQRTFLGRVKHFLNITDPRTVFVSERE
: ....:. : .. .. :: .::.: .
CCDS76 SLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVES
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LDWAKVMVEKSRMGVVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMII
.. .. .. .. : :.. ... : : .. :::... . . : . :: :
CCDS76 IENSRQLLCTNE-DVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPF-MAP
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 TGFM-LQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATA
: :. . . . .::. : .. : : : : . . . . : . : ..: .:
CCDS76 TVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRS--YTCKPLERSLLMAGAVASSTF
120 130 140 150 160 170
170 180 190 200 210
pF1KE6 VG-MNMLTKKAPPLVGRWV----PFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGH
.: . .... :.: :. : .. :. .:. : :. : :::: : :.. : .::
CCDS76 LGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGH
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 SRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLI
:: :.. .. ... :::.. . . .. :. ... ....: . : .. .: ..
CCDS76 SRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNP---GSLWILKLSCTVL
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 ---FMVPVACGLFPQKCELPVSYLEPKLQDTIKAKYGELEPYVYFNKGL
.::: . ..::: .. :: :.:. . : .....:.
CCDS76 AMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTE------ETEIFYHRGV
300 310 320 330
322 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:56:40 2016 done: Tue Nov 8 11:56:40 2016
Total Scan time: 2.090 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]