Result of FASTA (omim) for
pFN21AE6304
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6304, 443 aa
1>>>pF1KE6304 443 - 443 aa - 443 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3854+/-0.000332; mu= 17.5608+/- 0.021
mean_var=76.0766+/-15.053, 0's: 0 Z-trim(116.1): 12 B-trim: 22 in 1/53
Lambda= 0.147045
statistics sampled from 27038 (27050) to 27038 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.317), width: 16
Scan time: 8.610
The best scores are: opt bits E(85289)
NP_001294 (OMIM: 220110,256000,602125) protoheme I ( 443) 3007 647.3 2.3e-185
XP_016863520 (OMIM: 146500,607426,609825) PREDICTE ( 303) 193 50.2 8.8e-06
XP_011530169 (OMIM: 146500,607426,609825) PREDICTE ( 371) 193 50.3 1e-05
XP_011530168 (OMIM: 146500,607426,609825) PREDICTE ( 395) 193 50.3 1.1e-05
NP_056512 (OMIM: 146500,607426,609825) 4-hydroxybe ( 421) 193 50.3 1.1e-05
XP_011530165 (OMIM: 146500,607426,609825) PREDICTE ( 422) 193 50.3 1.1e-05
XP_011530164 (OMIM: 146500,607426,609825) PREDICTE ( 450) 193 50.3 1.2e-05
XP_011530162 (OMIM: 146500,607426,609825) PREDICTE ( 455) 193 50.3 1.2e-05
XP_011530161 (OMIM: 146500,607426,609825) PREDICTE ( 464) 193 50.3 1.2e-05
XP_011530159 (OMIM: 146500,607426,609825) PREDICTE ( 471) 193 50.3 1.2e-05
XP_011530157 (OMIM: 146500,607426,609825) PREDICTE ( 489) 193 50.4 1.3e-05
>>NP_001294 (OMIM: 220110,256000,602125) protoheme IX fa (443 aa)
initn: 3007 init1: 3007 opt: 3007 Z-score: 3448.7 bits: 647.3 E(85289): 2.3e-185
Smith-Waterman score: 3007; 99.8% identity (100.0% similar) in 443 aa overlap (1-443:1-443)
10 20 30 40 50 60
pF1KE6 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALA
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_001 LEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 CLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLP
370 380 390 400 410 420
430 440
pF1KE6 LLLLLMLTCKRPSGGGDAGPPPS
:::::::::::::::::::::::
NP_001 LLLLLMLTCKRPSGGGDAGPPPS
430 440
>>XP_016863520 (OMIM: 146500,607426,609825) PREDICTED: 4 (303 aa)
initn: 148 init1: 109 opt: 193 Z-score: 224.8 bits: 50.2 E(85289): 8.8e-06
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:26-176)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_016 MMTFAIAVYGDVVKGLGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
10 20 30 40 50
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_016 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
60 70 80 90 100
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_016 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
110 120 130 140 150 160
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_016 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
170 180 190 200 210 220
>>XP_011530169 (OMIM: 146500,607426,609825) PREDICTED: 4 (371 aa)
initn: 148 init1: 109 opt: 193 Z-score: 223.6 bits: 50.3 E(85289): 1e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:26-176)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 MMTFAIAVYGDVVKGLGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
10 20 30 40 50
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
60 70 80 90 100
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
110 120 130 140 150 160
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
170 180 190 200 210 220
>>XP_011530168 (OMIM: 146500,607426,609825) PREDICTED: 4 (395 aa)
initn: 177 init1: 109 opt: 193 Z-score: 223.2 bits: 50.3 E(85289): 1.1e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
>>NP_056512 (OMIM: 146500,607426,609825) 4-hydroxybenzoa (421 aa)
initn: 177 init1: 109 opt: 193 Z-score: 222.8 bits: 50.3 E(85289): 1.1e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
NP_056 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
NP_056 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
NP_056 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
NP_056 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
>>XP_011530165 (OMIM: 146500,607426,609825) PREDICTED: 4 (422 aa)
initn: 177 init1: 109 opt: 193 Z-score: 222.8 bits: 50.3 E(85289): 1.1e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
>>XP_011530164 (OMIM: 146500,607426,609825) PREDICTED: 4 (450 aa)
initn: 177 init1: 109 opt: 193 Z-score: 222.4 bits: 50.3 E(85289): 1.2e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
>>XP_011530162 (OMIM: 146500,607426,609825) PREDICTED: 4 (455 aa)
initn: 177 init1: 109 opt: 193 Z-score: 222.3 bits: 50.3 E(85289): 1.2e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
>>XP_011530161 (OMIM: 146500,607426,609825) PREDICTED: 4 (464 aa)
initn: 177 init1: 109 opt: 193 Z-score: 222.2 bits: 50.3 E(85289): 1.2e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
>>XP_011530159 (OMIM: 146500,607426,609825) PREDICTED: 4 (471 aa)
initn: 177 init1: 109 opt: 193 Z-score: 222.1 bits: 50.3 E(85289): 1.2e-05
Smith-Waterman score: 193; 31.5% identity (56.8% similar) in 162 aa overlap (172-320:144-294)
150 160 170 180 190
pF1KE6 RWKEMKLQVYDLPGILAQLSKIKLTALVVSTTAAGFALAPGPF-DWPCFLLTSVGTG--L
: . :.: :: : :: ..:. ::: :
XP_011 VDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDW--YMLSLFGTGAIL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 ASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGV---
:. .::.... .:....:: :::.. :.:: .: . . : :.:::
XP_011 MRGAGCTINDMWDQDYDKKVTRTANRPIAAGDIS-----TFQSFVFLGGQLTLALGVLLC
180 190 200 210 220
260 270 280 290 300 310
pF1KE6 -NPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAI---PPVMGWTAATGSLDAGA
: . ::: ...: : .:::: : ..: ..::.: :: : ..
XP_011 LNYYSIALGAGSLLLVIT-YPLMKRISY---WPQLALGLTFNWGALLGWSAIKGSCDPSV
230 240 250 260 270 280
320 330 340 350 360
pF1KE6 FL---LGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLS
: ..:....
XP_011 CLPLYFSGVMWTLIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSL
290 300 310 320 330 340
443 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:55:16 2016 done: Tue Nov 8 11:55:17 2016
Total Scan time: 8.610 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]