Result of FASTA (omim) for
pFN21AE6302
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6302, 311 aa
1>>>pF1KE6302 311 - 311 aa - 311 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0061+/-0.000363; mu= 17.7208+/- 0.023
mean_var=70.9616+/-14.806, 0's: 0 Z-trim(114.9): 251 B-trim: 2075 in 2/48
Lambda= 0.152252
statistics sampled from 24693 (24978) to 24693 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.293), width: 16
Scan time: 5.520
The best scores are: opt bits E(85289)
NP_005975 (OMIM: 190315,615182) tricarboxylate tra ( 311) 2088 467.6 1.4e-131
NP_001243463 (OMIM: 190315,615182) tricarboxylate ( 318) 1911 428.7 7.4e-120
NP_001274316 (OMIM: 190315,615182) tricarboxylate ( 208) 1400 316.3 3.3e-86
NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 424 102.1 1.5e-21
NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 412 99.4 9.2e-21
XP_011535589 (OMIM: 607571) PREDICTED: mitochondri ( 303) 400 96.8 5.8e-20
NP_000378 (OMIM: 212138,613698) mitochondrial carn ( 301) 385 93.5 5.6e-19
XP_005263263 (OMIM: 113730,601665) PREDICTED: mito ( 306) 375 91.3 2.6e-18
NP_068605 (OMIM: 113730,601665) mitochondrial brow ( 307) 372 90.7 4.1e-18
NP_003346 (OMIM: 601693,607447) mitochondrial unco ( 309) 370 90.2 5.6e-18
NP_060345 (OMIM: 205950,610819) solute carrier fam ( 304) 367 89.6 8.8e-18
XP_011532171 (OMIM: 205950,610819) PREDICTED: solu ( 298) 365 89.1 1.2e-17
XP_006713277 (OMIM: 205950,610819) PREDICTED: solu ( 300) 365 89.1 1.2e-17
XP_011510372 (OMIM: 603667,612949) PREDICTED: calc ( 587) 365 89.4 2e-17
XP_011535590 (OMIM: 607571) PREDICTED: mitochondri ( 269) 361 88.2 2e-17
NP_003696 (OMIM: 603667,612949) calcium-binding mi ( 678) 365 89.4 2.2e-17
XP_011530530 (OMIM: 113730,601665) PREDICTED: mito ( 277) 357 87.3 3.8e-17
NP_003347 (OMIM: 601665,602044) mitochondrial unco ( 312) 320 79.3 1.1e-14
NP_036272 (OMIM: 606794) mitochondrial dicarboxyla ( 287) 311 77.2 4.2e-14
XP_011535591 (OMIM: 607571) PREDICTED: mitochondri ( 267) 303 75.5 1.4e-13
NP_848621 (OMIM: 610823) mitochondrial coenzyme A ( 318) 299 74.6 2.9e-13
XP_005259918 (OMIM: 610823) PREDICTED: mitochondri ( 318) 299 74.6 2.9e-13
XP_011526239 (OMIM: 610823) PREDICTED: mitochondri ( 318) 299 74.6 2.9e-13
NP_001308473 (OMIM: 610823) mitochondrial coenzyme ( 318) 299 74.6 2.9e-13
XP_016882159 (OMIM: 610823) PREDICTED: mitochondri ( 382) 299 74.7 3.3e-13
NP_997000 (OMIM: 609911) solute carrier family 25 ( 308) 292 73.1 8.1e-13
NP_005879 (OMIM: 600370,610773) phosphate carrier ( 362) 292 73.2 9.1e-13
NP_112489 (OMIM: 609767) mitoferrin-2 [Homo sapien ( 364) 285 71.6 2.7e-12
NP_073714 (OMIM: 601665,602044) mitochondrial unco ( 275) 280 70.4 4.6e-12
NP_002626 (OMIM: 600370,610773) phosphate carrier ( 361) 281 70.7 4.9e-12
NP_998776 (OMIM: 600370,610773) phosphate carrier ( 361) 281 70.7 4.9e-12
XP_016876476 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_016876469 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
NP_689546 (OMIM: 615064) mitochondrial basic amino ( 237) 278 69.9 5.6e-12
XP_011534748 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_016876470 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_016876472 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_016876471 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_016876474 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_011534750 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
NP_001278742 (OMIM: 615064) mitochondrial basic am ( 237) 278 69.9 5.6e-12
NP_001278743 (OMIM: 615064) mitochondrial basic am ( 237) 278 69.9 5.6e-12
XP_016876475 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_011534749 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_016876473 (OMIM: 615064) PREDICTED: mitochondri ( 237) 278 69.9 5.6e-12
XP_011534746 (OMIM: 615064) PREDICTED: mitochondri ( 297) 278 70.0 6.6e-12
NP_001034444 (OMIM: 615064) mitochondrial basic am ( 303) 278 70.0 6.7e-12
NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [H ( 338) 278 70.1 7.3e-12
XP_006720102 (OMIM: 615064) PREDICTED: mitochondri ( 342) 278 70.1 7.4e-12
XP_011534745 (OMIM: 615064) PREDICTED: mitochondri ( 348) 278 70.1 7.5e-12
>>NP_005975 (OMIM: 190315,615182) tricarboxylate transpo (311 aa)
initn: 2088 init1: 2088 opt: 2088 Z-score: 2483.1 bits: 467.6 E(85289): 1.4e-131
Smith-Waterman score: 2088; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPAPRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 STRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 YQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEV
250 260 270 280 290 300
310
pF1KE6 VKLLNKVWKTD
:::::::::::
NP_005 VKLLNKVWKTD
310
>>NP_001243463 (OMIM: 190315,615182) tricarboxylate tran (318 aa)
initn: 1893 init1: 1893 opt: 1911 Z-score: 2272.8 bits: 428.7 E(85289): 7.4e-120
Smith-Waterman score: 1911; 92.6% identity (95.5% similar) in 309 aa overlap (4-311:10-318)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLT-HPGKAILAGGLAGGIEICITFPTEYVKTQL
:: :.. .. .: . . . : . :::::::::::::::::::::::
NP_001 MFPAALARRPRRPKSGTGEGPERQRPGGSLRSGFPVPAGGLAGGIEICITFPTEYVKTQL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 QLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 DAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 EQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 SVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIV
250 260 270 280 290 300
300 310
pF1KE6 FVIYDEVVKLLNKVWKTD
::::::::::::::::::
NP_001 FVIYDEVVKLLNKVWKTD
310
>>NP_001274316 (OMIM: 190315,615182) tricarboxylate tran (208 aa)
initn: 1400 init1: 1400 opt: 1400 Z-score: 1668.8 bits: 316.3 E(85289): 3.3e-86
Smith-Waterman score: 1400; 100.0% identity (100.0% similar) in 208 aa overlap (104-311:1-208)
80 90 100 110 120 130
pF1KE6 TVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGV
::::::::::::::::::::::::::::::
NP_001 MFEFLSNHMRDAQGRLDSTRGLLCGLGAGV
10 20 30
140 150 160 170 180 190
pF1KE6 AEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 NQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE6 HKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD
160 170 180 190 200
>>NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarboxyl (299 aa)
initn: 231 init1: 104 opt: 424 Z-score: 508.0 bits: 102.1 E(85289): 1.5e-21
Smith-Waterman score: 424; 29.3% identity (62.0% similar) in 300 aa overlap (27-308:15-299)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDE-RS
. :.::: :: .:::. : . :::..:... .
NP_085 MSAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCAT
10 20 30 40
60 70 80 90 100 110
pF1KE6 HPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRL
: :... : :. . .:..:.:.:. . . :: ::.: :: ... : .
NP_085 DPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFE----QYKKLLGYV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 DSTRGL---LCGLGAGVAEAVVVVCPMETIKVKFIHDQTS--PNPKYRGFFHGVREIVRE
. . .: . :::.:..::.:: :.:..:: . .... .:. :. .:.:...
NP_085 SLSPALTFAIAGLGSGLTEAIVV-NPFEVVKVGLQANRNTFAEQPSTVGY---ARQIIKK
110 120 130 140 150 160
180 190 200 210 220
pF1KE6 QG--LKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNP-NKPMNPLIT-----GVF
.: :.: .:::::. ..: . . : . ...: : :: .:.. :.
NP_085 EGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI----PVNK--DPILEFWRKFGI-
170 180 190 200 210
230 240 250 260 270 280
pF1KE6 GAIAGAASVFGNTPLDVIKTRMQGLEAH----KYRNTWDCGLQILKKEGLKAFYKGTVPR
: ..:. . : :.:: :.:.:: . :::. . . ..::. :.::: .:.
NP_085 GLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPK
220 230 240 250 260 270
290 300 310
pF1KE6 LGRVCLDVAIVFVIYDEVVKLLNKVWKTD
. :. :.....:. . . :.. :
NP_085 IMRLGPGGAVMLLVYEYTYSWLQENW
280 290
>>NP_001164641 (OMIM: 607571) mitochondrial 2-oxodicarbo (298 aa)
initn: 231 init1: 104 opt: 412 Z-score: 493.8 bits: 99.4 E(85289): 9.2e-21
Smith-Waterman score: 412; 29.2% identity (62.1% similar) in 298 aa overlap (27-306:15-297)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDE-RS
. :.::: :: .:::. : . :::..:... .
NP_001 MSAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCAT
10 20 30 40
60 70 80 90 100 110
pF1KE6 HPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRL
: :... : :. . .:..:.:.:. . . :: ::.: :: ... : .
NP_001 DPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFE----QYKKLLGYV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 DSTRGL---LCGLGAGVAEAVVVVCPMETIKVKFIHDQTS--PNPKYRGFFHGVREIVRE
. . .: . :::.:..::.:: :.:..:: . .... .:. :. .:.:...
NP_001 SLSPALTFAIAGLGSGLTEAIVV-NPFEVVKVGLQANRNTFAEQPSTVGY---ARQIIKK
110 120 130 140 150 160
180 190 200 210 220
pF1KE6 QG--LKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNP-NKPMNPLIT-----GVF
.: :.: .:::::. ..: . . : . ...: : :: .:.. :.
NP_001 EGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI----PVNK--DPILEFWRKFGI-
170 180 190 200 210
230 240 250 260 270 280
pF1KE6 GAIAGAASVFGNTPLDVIKTRMQGLEAH----KYRNTWDCGLQILKKEGLKAFYKGTVPR
: ..:. . : :.:: :.:.:: . :::. . . ..::. :.::: .:.
NP_001 GLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPK
220 230 240 250 260 270
290 300 310
pF1KE6 LGRVCLDVAIVFVIYDEVVKLLNKVWKTD
. :. :.....:. . . :..
NP_001 IMRLGPGGAVMLLVYEYTYSWLQEN
280 290
>>XP_011535589 (OMIM: 607571) PREDICTED: mitochondrial 2 (303 aa)
initn: 207 init1: 80 opt: 400 Z-score: 479.4 bits: 96.8 E(85289): 5.8e-20
Smith-Waterman score: 400; 28.6% identity (61.6% similar) in 297 aa overlap (30-308:22-303)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDE-RS
: .:: . .:::. : . :::..:... .
XP_011 MCSGPSGPLFTPLQAALCARRLPSGLLSLVEICLMHPLDVVKTRFQIQRCAT
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 HPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRL
: :... : :. . .:..:.:.:. . . :: ::.: :: ... : .
XP_011 DPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFE----QYKKLLGYV
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 DSTRGL---LCGLGAGVAEAVVVVCPMETIKVKFIHDQTS--PNPKYRGFFHGVREIVRE
. . .: . :::.:..::.:: :.:..:: . .... .:. :. .:.:...
XP_011 SLSPALTFAIAGLGSGLTEAIVV-NPFEVVKVGLQANRNTFAEQPSTVGY---ARQIIKK
110 120 130 140 150 160
180 190 200 210 220
pF1KE6 QG--LKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNP-NKPMNPLIT-----GVF
.: :.: .:::::. ..: . . : . ...: : :: .:.. :.
XP_011 EGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI----PVNK--DPILEFWRKFGI-
170 180 190 200 210
230 240 250 260 270 280
pF1KE6 GAIAGAASVFGNTPLDVIKTRMQGLEAH----KYRNTWDCGLQILKKEGLKAFYKGTVPR
: ..:. . : :.:: :.:.:: . :::. . . ..::. :.::: .:.
XP_011 GLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPK
220 230 240 250 260 270
290 300 310
pF1KE6 LGRVCLDVAIVFVIYDEVVKLLNKVWKTD
. :. :.....:. . . :.. :
XP_011 IMRLGPGGAVMLLVYEYTYSWLQENW
280 290 300
>>NP_000378 (OMIM: 212138,613698) mitochondrial carnitin (301 aa)
initn: 286 init1: 134 opt: 385 Z-score: 461.7 bits: 93.5 E(85289): 5.6e-19
Smith-Waterman score: 385; 29.1% identity (57.6% similar) in 302 aa overlap (19-310:4-298)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHPGKAILAGGLAGGIEICITF---PTEYVKTQLQLDE
. : : : .::::..: .:..: : . ::..:: .
NP_000 MADQPKPISPLKNLLAGGFGG---VCLVFVGHPLDTVKVRLQTQP
10 20 30 40
60 70 80 90 100 110
pF1KE6 RS---HPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSN-HMR
: .:: : : :: :.:. .:. :::::... . : : :: : : . .. ...
NP_000 PSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 DAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVR
. :. . . :. .:: .. .. : : :: . . .: . :: : . .... .
NP_000 HPEDVLSYPQLFAAGMLSGVF-TTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQ
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 EQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWY--RGDNPNKPMNPLITGVFGAIAG
: :..: :.: . :.... ... :... :.: . .: .. : : : :.:::
NP_000 EFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRIL-VAGGIAG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 AASVFGNTPLDVIKTRMQGLEAHKYRNTW-DCGLQILKKEGLKAFYKGTVPRLGRVCLDV
. : ::.:.:.: :: : . : .... ::. ..::: . :.
NP_000 IFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPAN
230 240 250 260 270 280
300 310
pF1KE6 AIVFVIYDEVVKLLNKVWKTD
: :. .. ..:.:: : :
NP_000 AACFLGFEVAMKFLN--WATPNL
290 300
>>XP_005263263 (OMIM: 113730,601665) PREDICTED: mitochon (306 aa)
initn: 361 init1: 161 opt: 375 Z-score: 449.7 bits: 91.3 E(85289): 2.6e-18
Smith-Waterman score: 375; 26.4% identity (62.4% similar) in 303 aa overlap (20-310:6-301)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHP--GKAILAGGLAGGIEICITFPTEYVKTQLQLD--
:. .:: : ....:.:. . :::: . .:..::..
XP_005 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGE
10 20 30 40
60 70 80 90 100 110
pF1KE6 -ERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDA
: ::.:. . .:...: . :: :: . : .: .:..:.:... ... . .
XP_005 CPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFL--T
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 QGRLDSTRG--LLCGLGAGVAEAVVVVCPMETIKVKFIHDQT---SPNPKYRGFFHGVRE
:. . : .: :: .: . :: . : :..::. .. :. . .:.: : ... :
XP_005 AGKETPSLGSKILAGLTTG-GVAVFIGQPTEVVKVR-LQAQSHLHGIKPRYTGTYNAYRI
110 120 130 140 150 160
180 190 200 210 220
pF1KE6 IVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNP--LITGVFGA
:. .:: : ..: : ..... . .. .. ... . .: : :....
XP_005 IATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSAL---
170 180 190 200 210
230 240 250 260 270 280
pF1KE6 IAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCL
::: .. ..:.::.:::. . .:... .:..... .:: ::.:: :: . :.
XP_005 IAGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGS
220 230 240 250 260 270
290 300 310
pF1KE6 DVAIVFVIYDEVVKLLNKVWKTD
.:.:: .... . :.: .:
XP_005 WNVIMFVCFEQLKRELSKSRQTMDCAT
280 290 300
>>NP_068605 (OMIM: 113730,601665) mitochondrial brown fa (307 aa)
initn: 333 init1: 161 opt: 372 Z-score: 446.1 bits: 90.7 E(85289): 4.1e-18
Smith-Waterman score: 372; 26.2% identity (62.3% similar) in 302 aa overlap (20-310:6-302)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHP--GKAILAGGLAGGIEICITFPTEYVKTQLQLD--
:. .:: : ....:.:. . :::: . .:..::..
NP_068 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGE
10 20 30 40
60 70 80 90 100 110
pF1KE6 -ERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDA
: ::.:. . .:...: . :: :: . : .: .:..:.:... ... . .
NP_068 CPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 QGRLDSTRG-LLCGLGAGVAEAVVVVCPMETIKVKFIHDQT---SPNPKYRGFFHGVREI
. : . .: :: .: . :: . : :..::. .. :. . .:.: : ... : :
NP_068 KETAPSLGSKILAGLTTG-GVAVFIGQPTEVVKVR-LQAQSHLHGIKPRYTGTYNAYRII
110 120 130 140 150 160
180 190 200 210 220
pF1KE6 VREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNP--LITGVFGAI
. .:: : ..: : ..... . .. .. ... . .: : :.... :
NP_068 ATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSAL---I
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE6 AGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLD
:: .. ..:.::.:::. . .:... .:..... .:: ::.:: :: . :.
NP_068 AGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSW
230 240 250 260 270 280
290 300 310
pF1KE6 VAIVFVIYDEVVKLLNKVWKTD
.:.:: .... . :.: .:
NP_068 NVIMFVCFEQLKRELSKSRQTMDCAT
290 300
>>NP_003346 (OMIM: 601693,607447) mitochondrial uncoupli (309 aa)
initn: 337 init1: 163 opt: 370 Z-score: 443.7 bits: 90.2 E(85289): 5.6e-18
Smith-Waterman score: 370; 28.1% identity (61.9% similar) in 299 aa overlap (19-304:5-298)
10 20 30 40 50
pF1KE6 MPAPRAPRALAAAAPASGKAKLTHPGKAI--LAGGLAGGIEICITFPTEYVKTQLQLDER
:: . : .. :..: :. : :::: . .:..::.. .
NP_003 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGE
10 20 30 40
60 70 80 90 100 110
pF1KE6 SHPP-------RYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNH
:. : .:::. . ::..: .:: :: . : .. :.::.:... ...
NP_003 SQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF
50 60 70 80 90 100
120 130 140 150 160
pF1KE6 MRDAQGRLDSTRG--LLCGLGAGVAEAVVVVCPMETIKVKF-IHDQTSPNPKYRGFFHGV
. ..: .. : :: : .: : ::.:. : ...::.: . ... . .:.. ..
NP_003 Y--TKGSEHASIGSRLLAGSTTG-ALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAY
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE6 REIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPL-ITGVFG
. :.::.:..: ..: . .: ... . .. .. ... : : .:..::
NP_003 KTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFG
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE6 AIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVC
:: .. .:.::.:::... .: .. :.: .:.::: .::::: .: . :.
NP_003 --AGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLG
230 240 250 260 270 280
290 300 310
pF1KE6 LDVAIVFVIYDEVVKLLNKVWKTD
...:: :... . :
NP_003 SWNVVMFVTYEQLKRALMAACTSREAPF
290 300
311 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:54:05 2016 done: Tue Nov 8 11:54:06 2016
Total Scan time: 5.520 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]