FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6296, 183 aa
  1>>>pF1KE6296 183 - 183 aa - 183 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3170+/-0.000363; mu= 12.5331+/- 0.023
 mean_var=59.1467+/-11.764, 0's: 0 Z-trim(113.1): 27  B-trim: 1301 in 1/51
 Lambda= 0.166766
 statistics sampled from 22203 (22222) to 22203 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.261), width:  16
 Scan time:  3.970

The best scores are:                                      opt bits E(85289)
NP_114100 (OMIM: 300308) ferritin heavy polypeptid ( 183) 1228 303.6 1.2e-82
NP_002023 (OMIM: 134770,615517) ferritin heavy cha ( 183)  800 200.6 1.2e-51
NP_803431 (OMIM: 608847) ferritin, mitochondrial p ( 242)  752 189.1 4.5e-48
NP_000137 (OMIM: 134790,600886,606159,615604) ferr ( 175)  576 146.7 1.9e-35


>>NP_114100 (OMIM: 300308) ferritin heavy polypeptide-li  (183 aa)
 initn: 1228 init1: 1228 opt: 1228  Z-score: 1604.9  bits: 303.6 E(85289): 1.2e-82
Smith-Waterman score: 1228; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KE6 MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 DDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRV
              130       140       150       160       170       180

          
pF1KE6 KET
       :::
NP_114 KET
          

>>NP_002023 (OMIM: 134770,615517) ferritin heavy chain [  (183 aa)
 initn: 798 init1: 798 opt: 800  Z-score: 1048.4  bits: 200.6 E(85289): 1.2e-51
Smith-Waterman score: 800; 65.0% identity (88.5% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KE6 MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLS
       :.::. :::::.:  . .:::: .:.::::.::.::::..::.::::::.:: .:::. :
NP_002 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 DDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQ
        .. :::.:::.::: :::.: :.::.::.:. ::::: ::: :.:::::::::::.:..
NP_002 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRV
       ::..:.::.:: :.:.:::.::::.::::: .:.::::. .::.::::::::: :::   
NP_002 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD
              130       140       150       160       170       180

          
pF1KE6 KET
       .:.
NP_002 NES
          

>>NP_803431 (OMIM: 608847) ferritin, mitochondrial precu  (242 aa)
 initn: 765 init1: 749 opt: 752  Z-score: 984.0  bits: 189.1 E(85289): 4.5e-48
Smith-Waterman score: 752; 65.4% identity (85.5% similar) in 179 aa overlap (4-182:63-241)

                                          10        20        30   
pF1KE6                            MATAQPSQVRQKYDTNCDAAINSHITLELYTSY
                                     : ::.:::..  . .:::: .:.::::.::
NP_803 APGRPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASY
             40        50        60        70        80        90  

            40        50        60        70        80        90   
pF1KE6 LYLSMAFYFNRDDVALENFFRYFLRLSDDKMEHAQKLMRLQNLRGGHICLHDIRKPECQG
       .:::::.::.::::::.:: ::::. : .. :::.::::::: :::.: :.::.::: . 
NP_803 VYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDD
            100       110       120       130       140       150  

           100       110       120       130       140       150   
pF1KE6 WESGLVAMESAFHLEKNVNQSLLDLYQLAVEKGDPQLCHFLESHYLHEQVKTIKELGGYV
       ::::: ::: :. ::::::::::.:. :: .::::.:: :::..::.::::.::::: .:
NP_803 WESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHV
            160       170       180       190       200       210  

           160       170       180   
pF1KE6 SNLRKICSPEAGLAEYLFDKLTLGGRVKET
        :: :. .:.:::::::::  :::.. :. 
NP_803 HNLVKMGAPDAGLAEYLFDTHTLGNENKQN
            220       230       240  

>>NP_000137 (OMIM: 134790,600886,606159,615604) ferritin  (175 aa)
 initn: 576 init1: 576 opt: 576  Z-score: 757.4  bits: 146.7 E(85289): 1.9e-35
Smith-Waterman score: 576; 49.4% identity (81.8% similar) in 170 aa overlap (7-176:3-172)

               10        20        30        40        50        60
pF1KE6 MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLS
             ::.::.:.:. .::.:: ..: : .:: :::..:::.:::::::.  ..: .:.
NP_000     MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELA
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KE6 DDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQ
       ..: :  ..:...:: :::.  ..::.::  . : .   ::..:. :::..::.::::. 
NP_000 EEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHA
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KE6 LAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRV
       :.  . ::.:: :::.:.: :.:: ::..: ...::... .:::::.::::..:::    
NP_000 LGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD 
        120       130       140       150       160       170      

          
pF1KE6 KET




183 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 11:52:52 2016 done: Tue Nov  8 11:52:53 2016
 Total Scan time:  3.970 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]