Result of FASTA (ccds) for
pFN21AE6294
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6294, 216 aa
1>>>pF1KE6294 216 - 216 aa - 216 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2771+/-0.000797; mu= 13.3900+/- 0.048
mean_var=61.4275+/-12.576, 0's: 0 Z-trim(107.7): 23 B-trim: 3 in 1/47
Lambda= 0.163641
statistics sampled from 9724 (9744) to 9724 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.299), width: 16
Scan time: 1.830
The best scores are: opt bits E(32554)
CCDS83353.1 AQP7 gene_id:364|Hs108|chr9 ( 216) 1495 361.2 2.9e-100
CCDS6541.1 AQP7 gene_id:364|Hs108|chr9 ( 342) 1305 316.4 1.4e-86
CCDS83354.1 AQP7 gene_id:364|Hs108|chr9 ( 256) 1296 314.2 4.6e-86
CCDS83356.1 AQP7 gene_id:364|Hs108|chr9 ( 257) 1296 314.2 4.6e-86
CCDS6542.1 AQP3 gene_id:360|Hs108|chr9 ( 292) 733 181.3 5.3e-46
CCDS10165.1 AQP9 gene_id:366|Hs108|chr15 ( 295) 620 154.7 5.8e-38
CCDS1065.1 AQP10 gene_id:89872|Hs108|chr1 ( 301) 609 152.1 3.5e-37
CCDS81887.1 AQP9 gene_id:366|Hs108|chr15 ( 230) 577 144.5 5.3e-35
>>CCDS83353.1 AQP7 gene_id:364|Hs108|chr9 (216 aa)
initn: 1495 init1: 1495 opt: 1495 Z-score: 1913.6 bits: 361.2 E(32554): 2.9e-100
Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE6 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 GQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 LTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFT
130 140 150 160 170 180
190 200 210
pF1KE6 FIAGWGKQVFRWHHLPGLHWLHHPTGAPEIGGFCGV
::::::::::::::::::::::::::::::::::::
CCDS83 FIAGWGKQVFRWHHLPGLHWLHHPTGAPEIGGFCGV
190 200 210
>>CCDS6541.1 AQP7 gene_id:364|Hs108|chr9 (342 aa)
initn: 1276 init1: 1276 opt: 1305 Z-score: 1668.1 bits: 316.4 E(32554): 1.4e-86
Smith-Waterman score: 1305; 91.6% identity (94.0% similar) in 215 aa overlap (1-215:58-268)
10 20 30
pF1KE6 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGR
::::::::::::::::::::::::::::::
CCDS65 ILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE6 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE6 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE6 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPEI
:::::::::::::::::::::::::::::::::::::::: : .: :. :: .
CCDS65 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFS----NGENWWWVPVVAPLL
210 220 230 240 250 260
pF1KE6 GGFCGV
:.. :
CCDS65 GAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPAN
270 280 290 300 310 320
>>CCDS83354.1 AQP7 gene_id:364|Hs108|chr9 (256 aa)
initn: 1296 init1: 1296 opt: 1296 Z-score: 1658.6 bits: 314.2 E(32554): 4.6e-86
Smith-Waterman score: 1296; 98.0% identity (98.5% similar) in 197 aa overlap (1-197:57-253)
10 20 30
pF1KE6 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGR
::::::::::::::::::::::::::::::
CCDS83 ILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE6 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE6 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE6 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPEI
:::::::::::::::::::::::::::::::::::::::::. ::
CCDS83 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRYCPCPGPFL
210 220 230 240 250
pF1KE6 GGFCGV
>>CCDS83356.1 AQP7 gene_id:364|Hs108|chr9 (257 aa)
initn: 1296 init1: 1296 opt: 1296 Z-score: 1658.5 bits: 314.2 E(32554): 4.6e-86
Smith-Waterman score: 1296; 98.0% identity (98.5% similar) in 197 aa overlap (1-197:58-254)
10 20 30
pF1KE6 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGR
::::::::::::::::::::::::::::::
CCDS83 ILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE6 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE6 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE6 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPEI
:::::::::::::::::::::::::::::::::::::::::. ::
CCDS83 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRYCPCPGPFL
210 220 230 240 250
pF1KE6 GGFCGV
>>CCDS6542.1 AQP3 gene_id:360|Hs108|chr9 (292 aa)
initn: 737 init1: 694 opt: 733 Z-score: 939.3 bits: 181.3 E(32554): 5.3e-46
Smith-Waterman score: 733; 48.4% identity (77.9% similar) in 217 aa overlap (1-216:46-258)
10 20
pF1KE6 MVLNK-KYGSYLGVNLGFGFGVTMGVHVAG
.::.. .:..: .::.:::.::.:. .::
CCDS65 HIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAG
20 30 40 50 60 70
30 40 50 60 70 80
pF1KE6 RISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQL
..::::.: ::::: : :.: :: :.:.:.:.: ::.::.:. ...:.: :: ::. .::
CCDS65 QVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQL
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE6 MVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVI
.:.:: .:::::::: :. . ::... :. : .:..::.: :::. : ::...
CCDS65 FVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTV
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE6 GILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPE
:..:..::.:.:.:.:::.::.::. ::.:: .::::. :: : :: : .:
CCDS65 GLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFT----TGQHWWWVPIVSPL
200 210 220 230 240 250
210
pF1KE6 IGGFCGV
.:.. ::
CCDS65 LGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
260 270 280 290
>>CCDS10165.1 AQP9 gene_id:366|Hs108|chr15 (295 aa)
initn: 624 init1: 606 opt: 620 Z-score: 795.1 bits: 154.7 E(32554): 5.8e-38
Smith-Waterman score: 620; 41.9% identity (76.7% similar) in 215 aa overlap (2-215:48-258)
10 20 30
pF1KE6 MVLNK-KYGSYLGVNLGFGFGVTMGVHVAGR
.:.. ..:. . .:.::...:.:...:::
CCDS10 LKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 ISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLM
.::.:.: ::..: : .::. : :.: :: .::::.:..:::.....: ... :.::.:.
CCDS10 VSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 VTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIG
..: ::: ::::: ...: .: ... : .: . .::: :..: : : : ..::
CCDS10 IVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE6 ILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPEI
.:...:. :::.:.: :.::.::: ::.:: .:::: .::: . .. :. :. .: .
CCDS10 LLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGN--NFWWI--PVVGPLV
200 210 220 230 240 250
pF1KE6 GGFCGV
:. :
CCDS10 GAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM
260 270 280 290
>>CCDS1065.1 AQP10 gene_id:89872|Hs108|chr1 (301 aa)
initn: 605 init1: 577 opt: 609 Z-score: 780.9 bits: 152.1 E(32554): 3.5e-37
Smith-Waterman score: 609; 42.3% identity (73.6% similar) in 208 aa overlap (8-215:53-256)
10 20 30
pF1KE6 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMN
:... . :. ...::....:.: .::::.:
CCDS10 QCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLN
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE6 AAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVAT
: ..: : .::.:: :.:.:.: :.:..: :... : :.. :. ...::.: :::: :
CCDS10 PAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKET
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE6 AGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIG
:.::::: ...: :::... :::: . :.:: :..:. . : : .:.:.:.. .:
CCDS10 ASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE6 VSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPEIGGFCGV
.:.: : : .::.::: ::.::..:::: .:: : : :. :: .:. :
CCDS10 LSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFS----AGNGWWWVPVVAPLVGATVGTA
210 220 230 240 250
CCDS10 TYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECKL
260 270 280 290 300
>>CCDS81887.1 AQP9 gene_id:366|Hs108|chr15 (230 aa)
initn: 582 init1: 564 opt: 577 Z-score: 741.9 bits: 144.5 E(32554): 5.3e-35
Smith-Waterman score: 577; 43.6% identity (75.9% similar) in 195 aa overlap (21-215:3-193)
10 20 30 40 50 60
pF1KE6 MVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVL
:.:...::: .::.:.: ::..: : .::. : :.: ::
CCDS81 MAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVG
10 20 30 40
70 80 90 100 110 120
pF1KE6 GQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAW
.::::.:..:::.....: ... :.::.:...: ::: ::::: ...: .: ...
CCDS81 AQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 LTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFT
: .: . .::: :..: : : : ..::.:...:. :::.:.: :.::.::: ::.::
CCDS81 ATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFT
110 120 130 140 150 160
190 200 210
pF1KE6 FIAGWGKQVFRWHHLPGLHWLHHPTGAPEIGGFCGV
.:::: .::: . .. :. :. .: .:. :
CCDS81 ALAGWGFEVFRAGN--NFWWI--PVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSE
170 180 190 200 210
CCDS81 DKPEKYELSVIM
220 230
216 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:52:06 2016 done: Tue Nov 8 11:52:06 2016
Total Scan time: 1.830 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]