Result of FASTA (omim) for
pFN21AE6279
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6279, 242 aa
1>>>pF1KE6279 242 - 242 aa - 242 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5910+/-0.000269; mu= 14.7985+/- 0.017
mean_var=90.9601+/-18.583, 0's: 0 Z-trim(121.2): 22 B-trim: 2052 in 1/56
Lambda= 0.134477
statistics sampled from 37383 (37410) to 37383 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.439), width: 16
Scan time: 5.610
The best scores are: opt bits E(85289)
NP_001027460 (OMIM: 300896,314375) UDP-galactose t ( 242) 1592 317.9 1e-86
NP_001269577 (OMIM: 300896,314375) UDP-galactose t ( 218) 1403 281.2 1e-75
NP_001269576 (OMIM: 300896,314375) UDP-galactose t ( 224) 1227 247.1 2e-65
NP_001035963 (OMIM: 300896,314375) UDP-galactose t ( 393) 875 179.0 1.1e-44
NP_005651 (OMIM: 300896,314375) UDP-galactose tran ( 396) 875 179.0 1.1e-44
NP_001269579 (OMIM: 300896,314375) UDP-galactose t ( 406) 719 148.7 1.4e-35
NP_001269580 (OMIM: 300896,314375) UDP-galactose t ( 421) 686 142.3 1.2e-33
XP_016856360 (OMIM: 605632,615553) PREDICTED: UDP- ( 228) 367 80.2 3.4e-15
XP_016856358 (OMIM: 605632,615553) PREDICTED: UDP- ( 284) 367 80.3 4e-15
XP_011539437 (OMIM: 605632,615553) PREDICTED: UDP- ( 326) 367 80.3 4.4e-15
NP_001258613 (OMIM: 605632,615553) UDP-N-acetylglu ( 220) 364 79.6 4.9e-15
XP_011539440 (OMIM: 605632,615553) PREDICTED: UDP- ( 262) 364 79.7 5.6e-15
XP_016856359 (OMIM: 605632,615553) PREDICTED: UDP- ( 269) 364 79.7 5.7e-15
XP_011539439 (OMIM: 605632,615553) PREDICTED: UDP- ( 311) 364 79.7 6.3e-15
XP_011539438 (OMIM: 605632,615553) PREDICTED: UDP- ( 325) 364 79.8 6.6e-15
XP_005270748 (OMIM: 605632,615553) PREDICTED: UDP- ( 325) 364 79.8 6.6e-15
NP_036375 (OMIM: 605632,615553) UDP-N-acetylglucos ( 325) 364 79.8 6.6e-15
NP_001258614 (OMIM: 605632,615553) UDP-N-acetylglu ( 367) 364 79.8 7.2e-15
NP_001269578 (OMIM: 300896,314375) UDP-galactose t ( 332) 315 70.3 4.8e-12
NP_001161870 (OMIM: 603585,605634) CMP-sialic acid ( 278) 247 57.0 4e-08
NP_006407 (OMIM: 603585,605634) CMP-sialic acid tr ( 337) 247 57.1 4.6e-08
>>NP_001027460 (OMIM: 300896,314375) UDP-galactose trans (242 aa)
initn: 1592 init1: 1592 opt: 1592 Z-score: 1678.0 bits: 317.9 E(85289): 1e-86
Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 242 aa overlap (1-242:1-242)
10 20 30 40 50 60
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 WRPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLP
190 200 210 220 230 240
pF1KE6 GH
::
NP_001 GH
>>NP_001269577 (OMIM: 300896,314375) UDP-galactose trans (218 aa)
initn: 1403 init1: 1403 opt: 1403 Z-score: 1480.4 bits: 281.2 E(85289): 1e-75
Smith-Waterman score: 1403; 100.0% identity (100.0% similar) in 212 aa overlap (31-242:7-218)
10 20 30 40 50 60
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
::::::::::::::::::::::::::::::
NP_001 MKLCRDAHRRLKYISLAVLVVQNASLILSIRYARTL
10 20 30
70 80 90 100 110 120
pF1KE6 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 WRPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLP
160 170 180 190 200 210
pF1KE6 GH
::
NP_001 GH
>>NP_001269576 (OMIM: 300896,314375) UDP-galactose trans (224 aa)
initn: 1250 init1: 1226 opt: 1227 Z-score: 1295.7 bits: 247.1 E(85289): 2e-65
Smith-Waterman score: 1230; 86.3% identity (90.2% similar) in 234 aa overlap (1-231:1-222)
10 20 30 40 50 60
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 WRPHHGALSAKVSAGEVRAGSNGGTQGRG---TGVEGVGHLQDPSRHPPGPGSSGFGRWS
::::::::::::. ::.: .:.: .: : . : ::...
NP_001 WRPHHGALSAKVAH-----------QGEGFLAAGIEDIG-LASFSLLALGPAGTKL
190 200 210 220
240
pF1KE6 FLPGH
>>NP_001035963 (OMIM: 300896,314375) UDP-galactose trans (393 aa)
initn: 907 init1: 875 opt: 875 Z-score: 923.3 bits: 179.0 E(85289): 1.1e-44
Smith-Waterman score: 875; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
::::::::::::::::::::::
NP_001 IYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVA
130 140 150 160 170 180
>>NP_005651 (OMIM: 300896,314375) UDP-galactose transloc (396 aa)
initn: 907 init1: 875 opt: 875 Z-score: 923.3 bits: 179.0 E(85289): 1.1e-44
Smith-Waterman score: 875; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPP
::::::::::::::::::::::
NP_005 IYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVA
130 140 150 160 170 180
>>NP_001269579 (OMIM: 300896,314375) UDP-galactose trans (406 aa)
initn: 893 init1: 686 opt: 719 Z-score: 759.6 bits: 148.7 E(85289): 1.4e-35
Smith-Waterman score: 839; 91.6% identity (91.6% similar) in 155 aa overlap (1-142:1-155)
10 20 30 40
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASA-------------AHRRLKYISLAVLVVQN
:::::::::::::::::::::::::::::: :::::::::::::::::
NP_001 MAAVGAGGSTAAPGPGAVSAGALEPGTASAGETVCPSSRMGGGAHRRLKYISLAVLVVQN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 ASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 QYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQPSPRCSQSHSLCLCLRLRALRSPAA
:::::::::::::::::::::::::::::::::::
NP_001 QYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 SRAATTTAAVFPPWRPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPG
NP_001 QWASLLLLFTGVAIVQAQQAGGGGPRPLDQNPGAGLAAVVASCLSSGFAGVYFEKILKGS
190 200 210 220 230 240
>>NP_001269580 (OMIM: 300896,314375) UDP-galactose trans (421 aa)
initn: 893 init1: 686 opt: 686 Z-score: 724.8 bits: 142.3 E(85289): 1.2e-33
Smith-Waterman score: 809; 83.5% identity (83.5% similar) in 170 aa overlap (1-142:1-170)
10 20 30
pF1KE6 MAAVGAGGSTAAPGPGAVSAGALEPGTASA----------------------------AH
:::::::::::::::::::::::::::::: ::
NP_001 MAAVGAGGSTAAPGPGAVSAGALEPGTASAELLLTWEEAEARGQGLPQPLPDTSVRIPAH
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 RRLKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 NVKHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQPSPRCSQSHS
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVKHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTT
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 LCLCLRLRALRSPAASRAATTTAAVFPPWRPHHGALSAKVSAGEVRAGSNGGTQGRGTGV
NP_001 ALFSVLMLNRSLSRLQWASLLLLFTGVAIVQAQQAGGGGPRPLDQNPGAGLAAVVASCLS
190 200 210 220 230 240
>>XP_016856360 (OMIM: 605632,615553) PREDICTED: UDP-N-ac (228 aa)
initn: 342 init1: 247 opt: 367 Z-score: 393.9 bits: 80.2 E(85289): 3.4e-15
Smith-Waterman score: 367; 50.8% identity (80.3% similar) in 122 aa overlap (35-153:5-126)
10 20 30 40 50 60
pF1KE6 GAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTLP--G
:::.::..:: :..::.:..::.::: :
XP_016 MFANLKYVSLGILVFQTTSLVLTMRYSRTLKEEG
10 20 30
70 80 90 100 110 120
pF1KE6 DRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSLIY
:....::::.::.:: ..:.::.. ... ... : ::. .: . ..:::::.:: ::
XP_016 PRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVLHDEILNKPMETLKLAIPSGIY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 TLQNNLQYVAISNLPAATFQ-PSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPPW
:::::: :::.::: :::.: :: .:. :
XP_016 TLQNNLLYVALSNLDAATYQWPSDSQLDSKELSAGSQFVGLMAVLTACFSSGFAGVYFEK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 RPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLPG
XP_016 ILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQCLFP
160 170 180 190 200 210
>>XP_016856358 (OMIM: 605632,615553) PREDICTED: UDP-N-ac (284 aa)
initn: 342 init1: 247 opt: 367 Z-score: 392.6 bits: 80.3 E(85289): 4e-15
Smith-Waterman score: 367; 50.8% identity (80.3% similar) in 122 aa overlap (35-153:5-126)
10 20 30 40 50 60
pF1KE6 GAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTLP--G
:::.::..:: :..::.:..::.::: :
XP_016 MFANLKYVSLGILVFQTTSLVLTMRYSRTLKEEG
10 20 30
70 80 90 100 110 120
pF1KE6 DRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSLIY
:....::::.::.:: ..:.::.. ... ... : ::. .: . ..:::::.:: ::
XP_016 PRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVLHDEILNKPMETLKLAIPSGIY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 TLQNNLQYVAISNLPAATFQ-PSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPPW
:::::: :::.::: :::.: :: .:. :
XP_016 TLQNNLLYVALSNLDAATYQWPSDSQLDSKELSAGSQFVGLMAVLTACFSSGFAGVYFEK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 RPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLPG
XP_016 ILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGG
160 170 180 190 200 210
>>XP_011539437 (OMIM: 605632,615553) PREDICTED: UDP-N-ac (326 aa)
initn: 342 init1: 247 opt: 367 Z-score: 391.8 bits: 80.3 E(85289): 4.4e-15
Smith-Waterman score: 367; 50.8% identity (80.3% similar) in 122 aa overlap (35-153:47-168)
10 20 30 40 50 60
pF1KE6 GAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTLP--G
:::.::..:: :..::.:..::.::: :
XP_011 DQHLELKKPQELKEMERLPLANEDKTMFANLKYVSLGILVFQTTSLVLTMRYSRTLKEEG
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE6 DRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSLIY
:....::::.::.:: ..:.::.. ... ... : ::. .: . ..:::::.:: ::
XP_011 PRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVLHDEILNKPMETLKLAIPSGIY
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE6 TLQNNLQYVAISNLPAATFQ-PSPRCSQSHSLCLCLRLRALRSPAASRAATTTAAVFPPW
:::::: :::.::: :::.: :: .:. :
XP_011 TLQNNLLYVALSNLDAATYQWPSDSQLDSKELSAGSQFVGLMAVLTACFSSGFAGVYFEK
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE6 RPHHGALSAKVSAGEVRAGSNGGTQGRGTGVEGVGHLQDPSRHPPGPGSSGFGRWSFLPG
XP_011 ILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGG
200 210 220 230 240 250
242 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:44:08 2016 done: Tue Nov 8 11:44:09 2016
Total Scan time: 5.610 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]