Result of FASTA (omim) for
pFN21AE6278
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6278, 228 aa
1>>>pF1KE6278 228 - 228 aa - 228 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1198+/-0.000341; mu= 14.6030+/- 0.021
mean_var=59.8932+/-12.267, 0's: 0 Z-trim(114.5): 301 B-trim: 61 in 1/52
Lambda= 0.165724
statistics sampled from 24093 (24409) to 24093 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.286), width: 16
Scan time: 4.200
The best scores are: opt bits E(85289)
NP_659205 (OMIM: 608159) testisin isoform 2 prepro ( 312) 335 88.3 1.6e-17
NP_006790 (OMIM: 608159) testisin isoform 1 prepro ( 314) 335 88.3 1.6e-17
XP_005262879 (OMIM: 264900,612416) PREDICTED: coag ( 594) 336 88.7 2.3e-17
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 306 81.4 1.7e-15
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 306 81.4 1.7e-15
NP_037402 (OMIM: 607950) probable threonine protea ( 385) 297 79.3 1e-14
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 296 79.0 1e-14
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343) 296 79.0 1.1e-14
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 292 78.1 2.1e-14
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 292 78.1 2.1e-14
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 281 75.5 2e-13
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 276 74.3 4.3e-13
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 276 74.4 4.6e-13
NP_001305324 (OMIM: 608018) serine protease 27 iso ( 188) 263 71.0 1.5e-12
XP_011520991 (OMIM: 608018) PREDICTED: serine prot ( 188) 263 71.0 1.5e-12
NP_114154 (OMIM: 608018) serine protease 27 isofor ( 290) 263 71.1 2.2e-12
NP_690851 (OMIM: 613797) serine protease 33 precur ( 280) 262 70.9 2.6e-12
XP_011520754 (OMIM: 613797) PREDICTED: serine prot ( 280) 262 70.9 2.6e-12
XP_011520753 (OMIM: 613797) PREDICTED: serine prot ( 280) 262 70.9 2.6e-12
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 264 71.4 2.7e-12
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 264 71.4 2.7e-12
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 261 70.6 3.3e-12
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 261 70.6 3.3e-12
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 260 70.4 3.4e-12
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 264 71.5 3.7e-12
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 264 71.5 3.7e-12
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 264 71.5 3.7e-12
NP_036349 (OMIM: 609272) tryptase delta precursor ( 242) 258 69.9 4.4e-12
XP_016861949 (OMIM: 142408) PREDICTED: hepatocyte ( 718) 255 69.4 1.8e-11
XP_016864340 (OMIM: 605369) PREDICTED: transmembra ( 234) 248 67.5 2.2e-11
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 255 69.5 2.4e-11
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 255 69.5 2.5e-11
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 255 69.5 2.5e-11
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 255 69.5 2.5e-11
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 255 69.5 2.5e-11
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 255 69.5 2.5e-11
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 255 69.5 2.5e-11
XP_005265767 (OMIM: 605369) PREDICTED: transmembra ( 301) 248 67.5 2.8e-11
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 248 67.6 3.4e-11
XP_011528034 (OMIM: 602060) PREDICTED: transmembra ( 410) 248 67.6 3.6e-11
NP_004253 (OMIM: 605369) transmembrane protease se ( 418) 248 67.6 3.7e-11
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 248 67.6 3.9e-11
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 248 67.6 4.2e-11
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 248 67.6 4.2e-11
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 248 67.6 4.5e-11
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268) 244 66.5 4.9e-11
XP_011538852 (OMIM: 167800,601405) PREDICTED: chym ( 280) 244 66.5 5e-11
XP_016878460 (OMIM: 610560) PREDICTED: polyserase- ( 621) 248 67.7 5.1e-11
XP_016878459 (OMIM: 610560) PREDICTED: polyserase- ( 634) 248 67.7 5.2e-11
XP_016878458 (OMIM: 610560) PREDICTED: polyserase- ( 637) 248 67.7 5.2e-11
>>NP_659205 (OMIM: 608159) testisin isoform 2 preproprot (312 aa)
initn: 426 init1: 223 opt: 335 Z-score: 435.8 bits: 88.3 E(85289): 1.6e-17
Smith-Waterman score: 460; 34.5% identity (58.0% similar) in 264 aa overlap (5-227:53-310)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAH
:::. :::. . :::: .:.. :..::::
NP_659 SQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAH
30 40 50 60 70 80
40 50 60 70 80
pF1KE6 CIQ----GTKEYSVVLGTSKLQPMNFSRALWVP---VRDIIMHPKYWGRAFIMGDVALVH
:.. . . : .: .: .: . : .: . :.: : . :.:::.
NP_659 CFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY--DIALVK
90 100 110 120 130 140
90 100 110
pF1KE6 LQTPVTFS----------ST-------------------ANSMLTPE-LQEAEVFIMDNK
:..:::.. :: ... .:. :::..: :..:.
NP_659 LSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNS
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE6 RCDRHYKKSFFPPVVPLVLGDMICATNY--GENLCYGDSGGPLACEVEGRWILAGVLSWE
:.. . : : . .:::.:: : :.. :.:::::::::. .: : ::.::
NP_659 MCNHLFLKYSFRKDI---FGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWG
210 220 230 240 250
180 190 200 210 220
pF1KE6 KACVKAQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLF--LCWLLQPQMGS
.: . . ::::: :... .::.: :.....: : : ::: : : : : .:
NP_659 VGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLLFFPLLWAL-PLLGPV
260 270 280 290 300 310
>>NP_006790 (OMIM: 608159) testisin isoform 1 preproprot (314 aa)
initn: 428 init1: 223 opt: 335 Z-score: 435.7 bits: 88.3 E(85289): 1.6e-17
Smith-Waterman score: 463; 34.6% identity (57.9% similar) in 266 aa overlap (5-227:53-312)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAH
:::. :::. . :::: .:.. :..::::
NP_006 SQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAH
30 40 50 60 70 80
40 50 60 70 80
pF1KE6 CIQGTKEYS------VVLGTSKLQPMNFSRALWVP---VRDIIMHPKYWGRAFIMGDVAL
:.. .. : : .: .: .: . : .: . :.: : . :.::
NP_006 CFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY--DIAL
90 100 110 120 130 140
90 100 110
pF1KE6 VHLQTPVTFS----------ST-------------------ANSMLTPE-LQEAEVFIMD
:.:..:::.. :: ... .:. :::..: :..
NP_006 VKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIIN
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE6 NKRCDRHYKKSFFPPVVPLVLGDMICATNY--GENLCYGDSGGPLACEVEGRWILAGVLS
:. :.. . : : . .:::.:: : :.. :.:::::::::. .: : ::.:
NP_006 NSMCNHLFLKYSFRKDI---FGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVS
210 220 230 240 250
180 190 200 210 220
pF1KE6 WEKACVKAQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLF--LCWLLQPQMGS
: .: . . ::::: :... .::.: :.....: : : ::: : : : : .:
NP_006 WGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLLFFPLLWAL-PLLGPV
260 270 280 290 300 310
>>XP_005262879 (OMIM: 264900,612416) PREDICTED: coagulat (594 aa)
initn: 330 init1: 203 opt: 336 Z-score: 432.8 bits: 88.7 E(85289): 2.3e-17
Smith-Waterman score: 408; 32.8% identity (64.2% similar) in 204 aa overlap (5-197:400-587)
10 20 30
pF1KE6 MTRHWPWEVSLRMEN---EHVCGGALIDPSWVVT
:::.:.:. . .:.:::..: .:..:
XP_005 YTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILT
370 380 390 400 410 420
40 50 60 70 80
pF1KE6 AAHCIQGTKE------YSVVLGTSKLQPMNFSRALWVPVRDIIMHPKYWGRAFIMGDVAL
::::. :.. :: .:. :... . . :..::.: .: : :.::
XP_005 AAHCFYGVESPKILRVYSGILNQSEIKE----DTSFFGVQEIIIHDQY-KMAESGYDIAL
430 440 450 460 470 480
90 100 110 120 130 140
pF1KE6 VHLQTPVTFSSTANSMLTPELQEAEVFIMDNKRCDRHYKKSFFPPVVPLVLGDMICA--T
..:.: :.... .. : :.:.. .. :..:...:. . ::::
XP_005 LKLETTVNYTDKIQNTL----QKAKIPLVTNEECQKRYRGH-------KITHKMICAGYR
490 500 510 520 530
150 160 170 180 190 200
pF1KE6 NYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACVKAQNPGVYTRITKYTKWIKKQMSN
. :.. : :::::::.:. . : :.:. :: ..:.. . ::::: ...:. ::
XP_005 EGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQA
540 550 560 570 580 590
210 220
pF1KE6 GAFSGPCASACLLFLCWLLQPQMGS
XP_005 V
>>NP_003285 (OMIM: 191080) tryptase alpha/beta-1 precurs (275 aa)
initn: 517 init1: 269 opt: 306 Z-score: 399.1 bits: 81.4 E(85289): 1.7e-15
Smith-Waterman score: 493; 36.4% identity (61.8% similar) in 228 aa overlap (5-197:42-267)
10 20 30
pF1KE6 MTRHWPWEVSLRMENE---HVCGGALIDPSWVVT
:::.::::... : :::.:: :.::.:
NP_003 LASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLT
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 AAHCI-QGTKEYSVVLGTSKLQPMNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQT
::::. .:. ... . : . .. : .:: ::.::... : : .:.::..:.
NP_003 AAHCVGPDVKDLAALRVQLREQHLYYQDQL-LPVSRIIVHPQFY-TAQIGADIALLELEE
80 90 100 110 120
100 110 120
pF1KE6 PVTFSSTANSMLTPE------------------------------LQEAEVFIMDNKRCD
::. :: .... : :....: ::.:. ::
NP_003 PVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICD
130 140 150 160 170 180
130 140 150 160 170
pF1KE6 RHYK-KSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACV
.:. .. : .: ::.:: : .. : :::::::.:.:.: :. :::.:: ..:.
NP_003 AKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCA
190 200 210 220 230 240
180 190 200 210 220
pF1KE6 KAQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS
. . ::.:::.: : ::
NP_003 QPNRPGIYTRVTYYLDWIHHYVPKKP
250 260 270
>>NP_077078 (OMIM: 191081) tryptase beta-2 preproprotein (275 aa)
initn: 520 init1: 269 opt: 306 Z-score: 399.1 bits: 81.4 E(85289): 1.7e-15
Smith-Waterman score: 496; 36.4% identity (62.3% similar) in 228 aa overlap (5-197:42-267)
10 20 30
pF1KE6 MTRHWPWEVSLRMENE---HVCGGALIDPSWVVT
:::.::::.... : :::.:: :.::.:
NP_077 LASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLT
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 AAHCI-QGTKEYSVVLGTSKLQPMNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQT
::::. .:. ... . : . .. : .:: ::.::... : : .:.::..:.
NP_077 AAHCVGPDVKDLAALRVQLREQHLYYQDQL-LPVSRIIVHPQFY-TAQIGADIALLELEE
80 90 100 110 120
100 110 120
pF1KE6 PVTFSSTANSMLTPE------------------------------LQEAEVFIMDNKRCD
::. :: .... : :....: ::.:. ::
NP_077 PVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICD
130 140 150 160 170 180
130 140 150 160 170
pF1KE6 RHYK-KSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACV
.:. .. : .: ::.:: : .. : :::::::.:.:.: :. :::.:: ..:.
NP_077 AKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCA
190 200 210 220 230 240
180 190 200 210 220
pF1KE6 KAQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS
. . ::.:::.: : ::
NP_077 QPNRPGIYTRVTYYLDWIHHYVPKKP
250 260 270
>>NP_037402 (OMIM: 607950) probable threonine protease P (385 aa)
initn: 418 init1: 197 opt: 297 Z-score: 385.3 bits: 79.3 E(85289): 1e-14
Smith-Waterman score: 428; 30.4% identity (59.2% similar) in 250 aa overlap (6-217:125-373)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAHC
:: ::.: .. :.:.:..: .::.:.:::
NP_037 EGKVDPYRSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHC
100 110 120 130 140 150
40 50 60 70 80
pF1KE6 -IQGTKEYSVVLGTSKLQPMNFSRALWVPVRDIIMHPKY-----WGRAFIMGDVALVHLQ
: ::: .:. .. :. . : ::: ..::: .: :. . .:..:..:.
NP_037 LIWRDVIYSVRVGSPWIDQMT-QTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLK
160 170 180 190 200 210
90 100 110
pF1KE6 TPVTFSSTANSMLTP------------------------------ELQEAEVFIMDNKRC
. .:. . . : .:: ::.:..::.:
NP_037 QELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKEC
220 230 240 250 260 270
120 130 140 150 160 170
pF1KE6 DRHYKK-SFFPPVVPLVLGDMICATN-YGENLCYGDSGGPLACEVEGRWILAGVLSWEKA
: :.. . .: .: .. ..:.:: . . :..:: .: ::.: .:: : :.:..:: .
NP_037 DNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAG
280 290 300 310 320 330
180 190 200 210 220
pF1KE6 CVKAQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS
: :.. : .: ....: .:: ... :.. : : ::.
NP_037 CQKSEAPPIYLQVSSYQHWIWDCLNGQALALPAPSRTLLLALPLPLSLLAAL
340 350 360 370 380
>>NP_036599 (OMIM: 609341) tryptase gamma preproprotein (321 aa)
initn: 511 init1: 217 opt: 296 Z-score: 385.2 bits: 79.0 E(85289): 1e-14
Smith-Waterman score: 508; 37.3% identity (61.8% similar) in 241 aa overlap (5-208:49-278)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAH
:::..:::.. :::::.:..:.::.::::
NP_036 LRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAH
20 30 40 50 60 70
40 50 60 70 80
pF1KE6 CIQGT---KEYSVVLGTSK--LQPMNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQ
:..:. ..:.: :: . :.: .:: ::.::.: . :. ::.:::.:.
NP_036 CFSGSLNSSDYQVHLGELEITLSP-HFST-----VRQIILHSSPSGQPGTSGDIALVELS
80 90 100 110 120 130
90 100 110
pF1KE6 TPVTFSSTANSMLTPE------------------------------LQEAEVFIMDNKRC
.:::.:: . :: :.:..: ..:.. :
NP_036 VPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETC
140 150 160 170 180 190
120 130 140 150 160 170
pF1KE6 DRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACV
: : : .. ::.:: . :. : ::::::.:.:.: :. ::..:: ..:
NP_036 RRDYPG----PGGSILQPDMLCARGPGDA-CQDDSGGPLVCQVNGAWVQAGIVSWGEGCG
200 210 220 230 240
180 190 200 210 220
pF1KE6 KAQNPGVYTRITKYTKWIKKQM--SNGAFSGPCASACLLFLCWLLQPQMGS
. . ::::::. :..::.... :.:. ::
NP_036 RPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCL
250 260 270 280 290 300
NP_036 LHPSADGTPFPAPD
310 320
>>NP_002764 (OMIM: 600823) prostasin preproprotein [Homo (343 aa)
initn: 500 init1: 208 opt: 296 Z-score: 384.7 bits: 79.0 E(85289): 1.1e-14
Smith-Waterman score: 484; 37.4% identity (63.4% similar) in 235 aa overlap (4-202:55-286)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAA
.:::.::. .:. :::::.:.. .::..::
NP_002 RSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAA
30 40 50 60 70 80
40 50 60 70 80
pF1KE6 HCIQGT--KE-YSVVLGTSKLQPMNFSRALWVP-VRDIIMHPKYWGRAFIMGDVALVHLQ
::. . :: : : ::. .:. ..:. : ..::: ::.: .. .::.::..:.
NP_002 HCFPSEHHKEAYEVKLGAHQLD--SYSEDAKVSTLKDIIPHPSYLQEGS-QGDIALLQLS
90 100 110 120 130 140
90 100 110
pF1KE6 TPVTFSS--------TAN---------------------SMLTPE-LQEAEVFIMDNKRC
:.::: .:: :.:::. ::. :: ... . :
NP_002 RPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE6 DRHYKKSFFPPVVPLVLGDMICA--TNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKA
. :. . : .: ::.:: .. :.. : :::::::.: ::: : :.:..:: :
NP_002 NCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA
210 220 230 240 250 260
180 190 200 210 220
pF1KE6 CVKAQNPGVYTRITKYTKWIKKQMSNGAFSGPCASACLLFLCWLLQPQMGS
: . ::::: ..:..::.....
NP_002 CGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLL
270 280 290 300 310 320
>>XP_011520748 (OMIM: 609341) PREDICTED: tryptase gamma (346 aa)
initn: 507 init1: 213 opt: 292 Z-score: 379.5 bits: 78.1 E(85289): 2.1e-14
Smith-Waterman score: 504; 37.3% identity (61.8% similar) in 241 aa overlap (5-208:74-303)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAH
:::..:::.. :::::.:..:.::.::::
XP_011 PSSFDLGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAH
50 60 70 80 90 100
40 50 60 70 80
pF1KE6 CIQGT---KEYSVVLGTSK--LQPMNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQ
:..:. ..:.: :: . :.: .:: ::.::.: . :. ::.:::.:.
XP_011 CFSGSLNSSDYQVHLGELEITLSP-HFST-----VRQIILHSSPSGQPGTSGDIALVELS
110 120 130 140 150
90 100 110
pF1KE6 TPVTFSSTANSMLTPE------------------------------LQEAEVFIMDNKRC
.:::.:: . :: :.:..: ..:.. :
XP_011 VPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETC
160 170 180 190 200 210
120 130 140 150 160 170
pF1KE6 DRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACV
: : : .. ::.:: . :. : ::::::.:.:.: :. ::..:: ..:
XP_011 RRDYPG----PGGSILQPDMLCARGPGDA-CQDDSGGPLVCQVNGAWVQAGTVSWGEGCG
220 230 240 250 260 270
180 190 200 210 220
pF1KE6 KAQNPGVYTRITKYTKWIKKQM--SNGAFSGPCASACLLFLCWLLQPQMGS
. . ::::::. :..::.... :.:. ::
XP_011 RPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCL
280 290 300 310 320 330
XP_011 LHPSADGTPFPAPD
340
>>XP_011520749 (OMIM: 609341) PREDICTED: tryptase gamma (346 aa)
initn: 507 init1: 213 opt: 292 Z-score: 379.5 bits: 78.1 E(85289): 2.1e-14
Smith-Waterman score: 504; 37.3% identity (61.8% similar) in 241 aa overlap (5-208:74-303)
10 20 30
pF1KE6 MTRHWPWEVSLRMENEHVCGGALIDPSWVVTAAH
:::..:::.. :::::.:..:.::.::::
XP_011 PSSFDLGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAH
50 60 70 80 90 100
40 50 60 70 80
pF1KE6 CIQGT---KEYSVVLGTSK--LQPMNFSRALWVPVRDIIMHPKYWGRAFIMGDVALVHLQ
:..:. ..:.: :: . :.: .:: ::.::.: . :. ::.:::.:.
XP_011 CFSGSLNSSDYQVHLGELEITLSP-HFST-----VRQIILHSSPSGQPGTSGDIALVELS
110 120 130 140 150
90 100 110
pF1KE6 TPVTFSSTANSMLTPE------------------------------LQEAEVFIMDNKRC
.:::.:: . :: :.:..: ..:.. :
XP_011 VPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETC
160 170 180 190 200 210
120 130 140 150 160 170
pF1KE6 DRHYKKSFFPPVVPLVLGDMICATNYGENLCYGDSGGPLACEVEGRWILAGVLSWEKACV
: : : .. ::.:: . :. : ::::::.:.:.: :. ::..:: ..:
XP_011 RRDYPG----PGGSILQPDMLCARGPGDA-CQDDSGGPLVCQVNGAWVQAGTVSWGEGCG
220 230 240 250 260 270
180 190 200 210 220
pF1KE6 KAQNPGVYTRITKYTKWIKKQM--SNGAFSGPCASACLLFLCWLLQPQMGS
. . ::::::. :..::.... :.:. ::
XP_011 RPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCL
280 290 300 310 320 330
XP_011 LHPSADGTPFPAPD
340
228 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:43:34 2016 done: Tue Nov 8 11:43:34 2016
Total Scan time: 4.200 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]