Result of FASTA (omim) for
pFN21AE6274
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6274, 190 aa
1>>>pF1KE6274 190 - 190 aa - 190 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9425+/-0.000284; mu= 15.1097+/- 0.018
mean_var=59.1206+/-11.912, 0's: 0 Z-trim(117.7): 21 B-trim: 0 in 0/55
Lambda= 0.166803
statistics sampled from 29888 (29909) to 29888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.351), width: 16
Scan time: 4.380
The best scores are: opt bits E(85289)
NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 1253 309.1 2.7e-84
XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 1180 291.6 5.5e-79
XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 756 189.5 2.1e-48
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 253 68.4 6e-12
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 251 68.0 8.7e-12
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 251 68.0 8.7e-12
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 251 68.0 8.7e-12
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 251 68.0 8.7e-12
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 245 66.5 2.3e-11
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 243 66.0 3.2e-11
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 186 52.3 4.2e-07
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 186 52.3 4.2e-07
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 186 52.3 4.5e-07
NP_067080 (OMIM: 605304) neuroglobin [Homo sapiens ( 151) 151 43.9 0.00015
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 141 41.5 0.00076
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 141 41.5 0.00076
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 139 41.0 0.0011
>>NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] (190 aa)
initn: 1253 init1: 1253 opt: 1253 Z-score: 1634.4 bits: 309.1 E(85289): 2.7e-84
Smith-Waterman score: 1253; 99.5% identity (100.0% similar) in 190 aa overlap (1-190:1-190)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_599 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_599 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
130 140 150 160 170 180
190
pF1KE6 PPATLPSSGP
::::::::::
NP_599 PPATLPSSGP
190
>>XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin isof (202 aa)
initn: 1180 init1: 1180 opt: 1180 Z-score: 1539.1 bits: 291.6 E(85289): 5.5e-79
Smith-Waterman score: 1180; 99.4% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_005 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
130 140 150 160 170 180
190
pF1KE6 PPATLPSSGP
XP_005 HSSWRRSPEGSWGRQASCPSCC
190 200
>>XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin isof (137 aa)
initn: 756 init1: 756 opt: 756 Z-score: 990.1 bits: 189.5 E(85289): 2.1e-48
Smith-Waterman score: 756; 100.0% identity (100.0% similar) in 115 aa overlap (66-180:1-115)
40 50 60 70 80 90
pF1KE6 ASCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVEN
::::::::::::::::::::::::::::::
XP_016 MEDPLEMERSPQLRKHACRVMGALNTVVEN
10 20 30
100 110 120 130 140 150
pF1KE6 LHDPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEEFASDFPPETQRAWAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEEFASDFPPETQRAWAKLR
40 50 60 70 80 90
160 170 180 190
pF1KE6 GLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP
:::::::::::::::::::::::::
XP_016 GLIYSHVTAAYKEVGWVQQVPNATTHSSWRRSPEGSWGRQASCPSCC
100 110 120 130
>>NP_005321 (OMIM: 142100) hemoglobin subunit epsilon [H (147 aa)
initn: 116 init1: 102 opt: 253 Z-score: 335.5 bits: 68.4 E(85289): 6e-12
Smith-Waterman score: 253; 27.2% identity (71.3% similar) in 136 aa overlap (19-154:4-134)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
.. :. :: ..:... . :..: : :..: .: ....:
NP_005 MVHFTAEEKAAVTSLWSKM--NVEEAGGEALGRLLVVYPWTQRFF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..: .. .: . .:... :. .:. ... ...:. :... ..: ... : : .:.
NP_005 DSFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNM---DNLKPAFAKLSELHCDKLHVD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
: ::.:..:.. ..: .:...: ::.: :: ::
NP_005 PENFKLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALAHKYH
110 120 130 140
190
pF1KE6 PPATLPSSGP
>>NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] (154 aa)
initn: 238 init1: 126 opt: 251 Z-score: 332.6 bits: 68.0 E(85289): 8.7e-12
Smith-Waterman score: 251; 29.4% identity (63.4% similar) in 153 aa overlap (19-171:3-152)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
::..: . : .:... :. : .:.:.: . : . . :
NP_976 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..:::... ::. : .:.::. :. ::. .... . . :: ..:: :::.
NP_976 DKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLA---QSHATKHKIP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
:....: :..:. . .:: ..: : : :. . ... :::.:.
NP_976 VKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
110 120 130 140 150
190
pF1KE6 PPATLPSSGP
>>NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] (154 aa)
initn: 238 init1: 126 opt: 251 Z-score: 332.6 bits: 68.0 E(85289): 8.7e-12
Smith-Waterman score: 251; 29.4% identity (63.4% similar) in 153 aa overlap (19-171:3-152)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
::..: . : .:... :. : .:.:.: . : . . :
NP_005 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..:::... ::. : .:.::. :. ::. .... . . :: ..:: :::.
NP_005 DKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLA---QSHATKHKIP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
:....: :..:. . .:: ..: : : :. . ... :::.:.
NP_005 VKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
110 120 130 140 150
190
pF1KE6 PPATLPSSGP
>>NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] (154 aa)
initn: 238 init1: 126 opt: 251 Z-score: 332.6 bits: 68.0 E(85289): 8.7e-12
Smith-Waterman score: 251; 29.4% identity (63.4% similar) in 153 aa overlap (19-171:3-152)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
::..: . : .:... :. : .:.:.: . : . . :
NP_976 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..:::... ::. : .:.::. :. ::. .... . . :: ..:: :::.
NP_976 DKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLA---QSHATKHKIP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
:....: :..:. . .:: ..: : : :. . ... :::.:.
NP_976 VKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
110 120 130 140 150
190
pF1KE6 PPATLPSSGP
>>XP_005261662 (OMIM: 160000) PREDICTED: myoglobin isofo (154 aa)
initn: 238 init1: 126 opt: 251 Z-score: 332.6 bits: 68.0 E(85289): 8.7e-12
Smith-Waterman score: 251; 29.4% identity (63.4% similar) in 153 aa overlap (19-171:3-152)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
::..: . : .:... :. : .:.:.: . : . . :
XP_005 MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..:::... ::. : .:.::. :. ::. .... . . :: ..:: :::.
XP_005 DKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLA---QSHATKHKIP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
:....: :..:. . .:: ..: : : :. . ... :::.:.
XP_005 VKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
110 120 130 140 150
190
pF1KE6 PPATLPSSGP
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 111 init1: 97 opt: 245 Z-score: 325.1 bits: 66.5 E(85289): 2.3e-11
Smith-Waterman score: 245; 25.0% identity (69.6% similar) in 148 aa overlap (19-166:4-146)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
..: .. .. ..:... . ::.: : :..: .: ....:
NP_000 MGHFTEEDKATITSLWGKV--NVEDAGGETLGRLLVVYPWTQRFF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..: .. . . .:... :. .:. .:. ....: : .....: ... : : .:.
NP_000 DSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDD---LKGTFAQLSELHCDKLHVD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
: ::.:..:.. :.: .:...: ::.: .: :. . : ... :
NP_000 PENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH
110 120 130 140
190
pF1KE6 PPATLPSSGP
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 118 init1: 97 opt: 243 Z-score: 322.5 bits: 66.0 E(85289): 3.2e-11
Smith-Waterman score: 243; 25.0% identity (69.6% similar) in 148 aa overlap (19-166:4-146)
10 20 30 40 50 60
pF1KE6 MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYASCEDVGVAILVRFFVNFPSAKQYF
..: .. .. ..:... . ::.: : :..: .: ....:
NP_000 MGHFTEEDKATITSLWGKV--NVEDAGGETLGRLLVVYPWTQRFF
10 20 30 40
70 80 90 100 110 120
pF1KE6 SQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVE
..: .. . . .:... :. .:. .:. ....: : .....: ... : : .:.
NP_000 DSFGNLSSASAIMGNPKVKAHGKKVLTSLGDATKHLDD---LKGTFAQLSELHCDKLHVD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 PVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATT
: ::.:..:.. :.: .:...: ::.: .: :. . : ... :
NP_000 PENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH
110 120 130 140
190
pF1KE6 PPATLPSSGP
190 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:41:29 2016 done: Tue Nov 8 11:41:30 2016
Total Scan time: 4.380 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]