Result of FASTA (ccds) for
pFN21AE6273
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6273, 192 aa
1>>>pF1KE6273 192 - 192 aa - 192 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7066+/-0.000942; mu= 10.0395+/- 0.056
mean_var=54.5233+/-11.225, 0's: 0 Z-trim(103.3): 28 B-trim: 437 in 1/46
Lambda= 0.173693
statistics sampled from 7336 (7357) to 7336 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.226), width: 16
Scan time: 1.250
The best scores are: opt bits E(32554)
CCDS33407.1 TRPM8 gene_id:79054|Hs108|chr2 (1104) 1137 293.1 4.2e-79
CCDS13710.1 TRPM2 gene_id:7226|Hs108|chr21 (1503) 609 160.7 3.8e-39
CCDS82681.1 TRPM2 gene_id:7226|Hs108|chr21 (1553) 609 160.7 4e-39
CCDS43835.1 TRPM3 gene_id:80036|Hs108|chr9 (1707) 450 120.9 4.3e-27
CCDS73725.1 TRPM7 gene_id:54822|Hs108|chr15 (1864) 443 119.2 1.6e-26
CCDS42035.1 TRPM7 gene_id:54822|Hs108|chr15 (1865) 443 119.2 1.6e-26
CCDS56098.1 TRPM4 gene_id:54795|Hs108|chr19 (1069) 437 117.6 2.6e-26
CCDS33073.1 TRPM4 gene_id:54795|Hs108|chr19 (1214) 437 117.6 2.9e-26
CCDS10024.2 TRPM1 gene_id:4308|Hs108|chr15 (1603) 430 115.9 1.3e-25
CCDS58346.1 TRPM1 gene_id:4308|Hs108|chr15 (1625) 430 115.9 1.3e-25
CCDS58347.1 TRPM1 gene_id:4308|Hs108|chr15 (1642) 430 115.9 1.3e-25
CCDS55318.1 TRPM6 gene_id:140803|Hs108|chr9 (2017) 374 101.9 2.7e-21
CCDS55319.1 TRPM6 gene_id:140803|Hs108|chr9 (2017) 374 101.9 2.7e-21
CCDS6647.1 TRPM6 gene_id:140803|Hs108|chr9 (2022) 374 101.9 2.7e-21
CCDS6637.1 TRPM3 gene_id:80036|Hs108|chr9 ( 230) 340 93.3 1.2e-19
CCDS65064.1 TRPM3 gene_id:80036|Hs108|chr9 (1556) 340 93.3 7.8e-19
CCDS6634.1 TRPM3 gene_id:80036|Hs108|chr9 (1566) 340 93.3 7.8e-19
CCDS6636.1 TRPM3 gene_id:80036|Hs108|chr9 (1569) 340 93.3 7.8e-19
CCDS6635.1 TRPM3 gene_id:80036|Hs108|chr9 (1579) 340 93.3 7.9e-19
CCDS31340.1 TRPM5 gene_id:29850|Hs108|chr11 (1165) 330 90.8 3.3e-18
>>CCDS33407.1 TRPM8 gene_id:79054|Hs108|chr2 (1104 aa)
initn: 1137 init1: 1137 opt: 1137 Z-score: 1533.7 bits: 293.1 E(32554): 4.2e-79
Smith-Waterman score: 1137; 100.0% identity (100.0% similar) in 169 aa overlap (15-183:65-233)
10 20 30 40
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHMEGTQINQSEKWNYKKH
::::::::::::::::::::::::::::::
CCDS33 SYSESDLVNFIQANFKKRECVFFTKDSKATENVCKCGYAQSQHMEGTQINQSEKWNYKKH
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE6 TKEFPTDAFGDIQFETLGKKGKYIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TKEFPTDAFGDIQFETLGKKGKYIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKN
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE6 FALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGI
160 170 180 190 200 210
170 180 190
pF1KE6 AAWGMVSNRDTLIRNCDAEVPVGQEEVC
:::::::::::::::::::
CCDS33 AAWGMVSNRDTLIRNCDAEGYFLAQYLMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVE
220 230 240 250 260 270
>>CCDS13710.1 TRPM2 gene_id:7226|Hs108|chr21 (1503 aa)
initn: 435 init1: 236 opt: 609 Z-score: 816.2 bits: 160.7 E(32554): 3.8e-39
Smith-Waterman score: 609; 53.3% identity (80.8% similar) in 167 aa overlap (17-177:88-254)
10 20 30 40
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHME-GTQIN--QSEKWNYKK
::.:::.. ::.: .:. . :. .:. ::
CCDS13 SLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKK
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE6 HTKEFPTDAFGDIQFETLGKK-GKYIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGA
:..:.:::::::: : :..: ::.:.: :: . ..:.:.:::: : .:::.:::::::
CCDS13 HVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGA
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE6 KNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEEN-IV
::: .:::...:: : :. .::. ::::.:::.: :.:: .::.::: ..: : .:. ..
CCDS13 KNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELI
180 190 200 210 220 230
170 180 190
pF1KE6 AIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
.::.:.:: : :. ::
CCDS13 TIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGV
240 250 260 270 280 290
>>CCDS82681.1 TRPM2 gene_id:7226|Hs108|chr21 (1553 aa)
initn: 435 init1: 236 opt: 609 Z-score: 816.0 bits: 160.7 E(32554): 4e-39
Smith-Waterman score: 609; 53.3% identity (80.8% similar) in 167 aa overlap (17-177:88-254)
10 20 30 40
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHME-GTQIN--QSEKWNYKK
::.:::.. ::.: .:. . :. .:. ::
CCDS82 SLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKK
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE6 HTKEFPTDAFGDIQFETLGKK-GKYIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGA
:..:.:::::::: : :..: ::.:.: :: . ..:.:.:::: : .:::.:::::::
CCDS82 HVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGA
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE6 KNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEEN-IV
::: .:::...:: : :. .::. ::::.:::.: :.:: .::.::: ..: : .:. ..
CCDS82 KNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELI
180 190 200 210 220 230
170 180 190
pF1KE6 AIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
.::.:.:: : :. ::
CCDS82 TIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGV
240 250 260 270 280 290
>>CCDS43835.1 TRPM3 gene_id:80036|Hs108|chr9 (1707 aa)
initn: 417 init1: 157 opt: 450 Z-score: 599.9 bits: 120.9 E(32554): 4.3e-27
Smith-Waterman score: 450; 44.5% identity (80.1% similar) in 146 aa overlap (35-177:121-264)
10 20 30 40 50 60
pF1KE6 LPVHTIVLIRENVCKCGYAQSQHMEGTQINQSEKWNYKKHTKEFPTDAFGDIQFETLGKK
:::::. .:::. :::::: :.:. :..
CCDS43 RLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHS
100 110 120 130 140 150
70 80 90 100 110 120
pF1KE6 GK--YIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSR-LIYI
.: :.:.: :: ..: .:.:..:.:. :.:.::: :: .:: :.:.....:.. ::
CCDS43 NKAMYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKA
160 170 180 190 200 210
130 140 150 160 170 180
pF1KE6 AQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGIAAWGMVSNRDTLIRNCD
:.. ::::.:::.. :.....:....:. . .:. .: .:::: ::.: :.. ::
CCDS43 AMTTGAWIFTGGVNTGVIRHVGDALKDH--ASKSRGKICTIGIAPWGIVENQEDLIGRDV
220 230 240 250 260
190
pF1KE6 AEVPVGQEEVC
CCDS43 VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRIGQ
270 280 290 300 310 320
>>CCDS73725.1 TRPM7 gene_id:54822|Hs108|chr15 (1864 aa)
initn: 416 init1: 181 opt: 443 Z-score: 589.7 bits: 119.2 E(32554): 1.6e-26
Smith-Waterman score: 443; 39.3% identity (76.3% similar) in 173 aa overlap (12-177:47-217)
10 20 30
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHME---GTQINQS-E
:.....: . .. . : ..::. :
CCDS73 VYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIE
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 KWNYKKHTKEFPTDAFGDIQFE--TLGKKGKYIRLSCDTDAEILYELLTQHWHLKTPNLV
.:. .:::.. ::::.: :.:. . . ..::.::: :: :.. .:: ..:... :.::
CCDS73 EWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 ISVTGGAKNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRS
::: :: ..: :.::....... :: : . ::::::::.. :. :..:....... :::
CCDS73 ISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHA-SRS
140 150 160 170 180 190
160 170 180 190
pF1KE6 SEENIVAIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
:.. : .:::: ::.. ::. :.
CCDS73 SRK-ICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVG
200 210 220 230 240 250
>>CCDS42035.1 TRPM7 gene_id:54822|Hs108|chr15 (1865 aa)
initn: 416 init1: 181 opt: 443 Z-score: 589.7 bits: 119.2 E(32554): 1.6e-26
Smith-Waterman score: 443; 39.3% identity (76.3% similar) in 173 aa overlap (12-177:47-217)
10 20 30
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHME---GTQINQS-E
:.....: . .. . : ..::. :
CCDS42 VYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIE
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 KWNYKKHTKEFPTDAFGDIQFE--TLGKKGKYIRLSCDTDAEILYELLTQHWHLKTPNLV
.:. .:::.. ::::.: :.:. . . ..::.::: :: :.. .:: ..:... :.::
CCDS42 EWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 ISVTGGAKNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRS
::: :: ..: :.::....... :: : . ::::::::.. :. :..:....... :::
CCDS42 ISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHA-SRS
140 150 160 170 180 190
160 170 180 190
pF1KE6 SEENIVAIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
:.. : .:::: ::.. ::. :.
CCDS42 SRK-ICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVG
200 210 220 230 240 250
>>CCDS56098.1 TRPM4 gene_id:54795|Hs108|chr19 (1069 aa)
initn: 376 init1: 223 opt: 437 Z-score: 585.9 bits: 117.6 E(32554): 2.6e-26
Smith-Waterman score: 437; 40.0% identity (68.2% similar) in 170 aa overlap (17-177:34-201)
10 20 30
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQH----ME---GTQINQSEKW
.:.:: .. : :: :. . :
CCDS56 PEKEQSWIPKIFKKKTCTTFIVDSTDPGGTLCQCGRPRTAHPAVAMEDAFGAAVVTV--W
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 NYKKHTKEFPTDAFGDIQFETLGKK-GKYIRLSCDTDAEILYELLTQHWHLKTPNLVISV
. :: : ::::.:...: :.: ....::: :: .: :.:. : ...::::.::
CCDS56 DSDAHTTEKPTDAYGELDFTGAGRKHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 TGGAKNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEE
::. . .:. .. .. : :. ::: ::::.::: : :. ...: .:::. .. ..
CCDS56 LGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGT
130 140 150 160 170 180
160 170 180 190
pF1KE6 NIVAIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
..::.:.: ::.: ::::::
CCDS56 KVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHG
190 200 210 220 230 240
>>CCDS33073.1 TRPM4 gene_id:54795|Hs108|chr19 (1214 aa)
initn: 376 init1: 223 opt: 437 Z-score: 584.9 bits: 117.6 E(32554): 2.9e-26
Smith-Waterman score: 437; 40.0% identity (68.2% similar) in 170 aa overlap (17-177:34-201)
10 20 30
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQH----ME---GTQINQSEKW
.:.:: .. : :: :. . :
CCDS33 PEKEQSWIPKIFKKKTCTTFIVDSTDPGGTLCQCGRPRTAHPAVAMEDAFGAAVVTV--W
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 NYKKHTKEFPTDAFGDIQFETLGKK-GKYIRLSCDTDAEILYELLTQHWHLKTPNLVISV
. :: : ::::.:...: :.: ....::: :: .: :.:. : ...::::.::
CCDS33 DSDAHTTEKPTDAYGELDFTGAGRKHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 TGGAKNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEE
::. . .:. .. .. : :. ::: ::::.::: : :. ...: .:::. .. ..
CCDS33 LGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGT
130 140 150 160 170 180
160 170 180 190
pF1KE6 NIVAIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
..::.:.: ::.: ::::::
CCDS33 KVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHG
190 200 210 220 230 240
>>CCDS10024.2 TRPM1 gene_id:4308|Hs108|chr15 (1603 aa)
initn: 406 init1: 167 opt: 430 Z-score: 573.3 bits: 115.9 E(32554): 1.3e-25
Smith-Waterman score: 444; 38.0% identity (69.3% similar) in 179 aa overlap (16-177:5-181)
10 20 30 40
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHM-------------EGTQIN-QSEKWNYKKHTK
: : :: .::. :. :.. : :::. :::.
CCDS10 MKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQ
10 20 30 40
50 60 70 80 90 100
pF1KE6 EFPTDAFGDIQFETLGKKGK--YIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKN
.:::..: ..:. : ..: :::.: :: . : .:... :.:. :.:.::: :: .:
CCDS10 SYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQN
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE6 FALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIG
: ..:.....:.. :: :.. ::::.:::. :.....:....:. : .:. . :::
CCDS10 FEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDH--SSKSRGRVCAIG
110 120 130 140 150 160
170 180 190
pF1KE6 IAAWGMVSNRDTLIRNCDAEVPVGQEEVC
:: ::.: :.. :.
CCDS10 IAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLR
170 180 190 200 210 220
>>CCDS58346.1 TRPM1 gene_id:4308|Hs108|chr15 (1625 aa)
initn: 406 init1: 167 opt: 430 Z-score: 573.2 bits: 115.9 E(32554): 1.3e-25
Smith-Waterman score: 444; 38.0% identity (69.3% similar) in 179 aa overlap (16-177:27-203)
10 20 30
pF1KE6 MKSFLPVHTIVLIRENVCKCGYAQSQHM-------------EGTQIN-Q
: : :: .::. :. :.. :
CCDS58 MGQKSWIEKTFCKRECIFVIPSMKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 SEKWNYKKHTKEFPTDAFGDIQFETLGKKGK--YIRLSCDTDAEILYELLTQHWHLKTPN
:::. :::. .:::..: ..:. : ..: :::.: :: . : .:... :.:. :.
CCDS58 PEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LVISVTGGAKNFALKPRMRKIFSR-LIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTIS
:.::: :: .:: ..:.....:.. :: :.. ::::.:::. :.....:....:. :
CCDS58 LLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDH--S
130 140 150 160 170
160 170 180 190
pF1KE6 RSSEENIVAIGIAAWGMVSNRDTLIRNCDAEVPVGQEEVC
.:. . ::::: ::.: :.. :.
CCDS58 SKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGT
180 190 200 210 220 230
192 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:40:55 2016 done: Tue Nov 8 11:40:55 2016
Total Scan time: 1.250 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]