Result of FASTA (omim) for
pFN21AE6265
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6265, 264 aa
1>>>pF1KE6265 264 - 264 aa - 264 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9180+/-0.000376; mu= 17.4141+/- 0.023
mean_var=65.8754+/-13.602, 0's: 0 Z-trim(114.6): 315 B-trim: 2030 in 2/51
Lambda= 0.158020
statistics sampled from 24155 (24475) to 24155 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.287), width: 16
Scan time: 7.050
The best scores are: opt bits E(85289)
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 1795 417.7 1.1e-116
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 1047 247.2 2.3e-65
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269) 731 175.2 1.1e-43
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269) 692 166.3 5.4e-41
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 651 157.0 4.1e-38
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268) 649 156.5 4.8e-38
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 651 157.1 5.3e-38
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 649 156.6 7.2e-38
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 633 153.2 1.4e-36
NP_001316119 (OMIM: 118890) chymotrypsinogen B iso ( 233) 626 151.2 1.6e-36
NP_001962 (OMIM: 130120) chymotrypsin-like elastas ( 258) 617 149.2 7.3e-36
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 599 145.5 3.7e-34
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 599 145.5 3.7e-34
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 599 145.5 3.7e-34
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 599 145.5 3.7e-34
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 599 145.5 3.8e-34
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 599 145.5 3.8e-34
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 599 145.5 3.8e-34
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 593 143.8 4.5e-34
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417) 593 143.8 4.7e-34
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 593 143.8 4.7e-34
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417) 593 143.8 4.7e-34
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417) 593 143.8 4.7e-34
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 593 143.8 4.7e-34
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 593 143.9 4.9e-34
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 593 143.9 4.9e-34
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 593 144.0 6.6e-34
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 593 144.0 6.6e-34
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 593 144.0 6.6e-34
NP_031369 (OMIM: 613578) trypsin-3 isoform 1 prepr ( 304) 574 139.4 7.4e-33
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 575 139.7 7.6e-33
NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240) 572 138.9 8.5e-33
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 575 139.8 8.6e-33
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 575 139.8 9.2e-33
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 575 139.8 9.2e-33
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 575 139.8 9.7e-33
NP_892018 (OMIM: 610477) transmembrane protease se (1059) 577 140.5 1.2e-32
XP_011526280 (OMIM: 610477) PREDICTED: transmembra (1093) 577 140.5 1.2e-32
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 569 138.3 1.7e-32
NP_001265514 (OMIM: 605236,614595) atrial natriure ( 938) 573 139.5 2.1e-32
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 566 137.5 2.2e-32
NP_006578 (OMIM: 605236,614595) atrial natriuretic (1042) 573 139.6 2.3e-32
NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247) 564 137.1 3.1e-32
NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261) 564 137.1 3.2e-32
XP_011516267 (OMIM: 613578) PREDICTED: trypsin-3 i ( 333) 565 137.4 3.3e-32
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 566 137.7 3.7e-32
XP_011526282 (OMIM: 610477) PREDICTED: transmembra ( 690) 566 137.8 5e-32
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 560 136.3 7.5e-32
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 560 136.3 7.5e-32
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536) 561 136.6 9e-32
>>NP_001898 (OMIM: 118888) chymotrypsin-like protease CT (264 aa)
initn: 1795 init1: 1795 opt: 1795 Z-score: 2216.1 bits: 417.7 E(85289): 1.1e-116
Smith-Waterman score: 1795; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264)
10 20 30 40 50 60
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
190 200 210 220 230 240
250 260
pF1KE6 VRAPAVYTRVSKFSTWINQVIAYN
::::::::::::::::::::::::
NP_001 VRAPAVYTRVSKFSTWINQVIAYN
250 260
>>NP_001897 (OMIM: 118890) chymotrypsinogen B isoform 1 (263 aa)
initn: 1050 init1: 687 opt: 1047 Z-score: 1294.5 bits: 247.2 E(85289): 2.3e-65
Smith-Waterman score: 1047; 53.8% identity (82.2% similar) in 264 aa overlap (1-264:1-263)
10 20 30 40 50 60
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
: : : . :.:...:::.:::.:.:: .::::::.:: :::::::::::..:::::
NP_001 MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
::::::..::::::::.: . :: ::.:..:. : .:::...... .:... :.::
NP_001 GGSLISEDWVVTAAHCGVRTS-DVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNN
70 80 90 100 110
130 140 150 160 170 180
pF1KE6 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
:.::::::.::... .: ::: :... . : :.:::::. . .: :: .:::.:::
NP_001 DITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
:.. .:.. :: ::: :::::..:.:::.::::::::::: ..:.:.::::::. .:.
NP_001 LLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCS
180 190 200 210 220 230
250 260
pF1KE6 VRAPAVYTRVSKFSTWINQVIAYN
. .:.::.::.:. :.....: :
NP_001 TSSPGVYARVTKLIPWVQKILAAN
240 250 260
>>NP_254275 (OMIM: 609443) chymotrypsin-like elastase fa (269 aa)
initn: 486 init1: 176 opt: 731 Z-score: 905.0 bits: 175.2 E(85289): 1.1e-43
Smith-Waterman score: 731; 45.5% identity (69.8% similar) in 275 aa overlap (2-264:1-269)
10 20 30 40 50
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---F
.. .: :: .. :. .:: :. : .. :.:.::.: .::::::::: ::. .
NP_254 MIRTLLLSTLVAGA-LSCGDPTYPPYVT---RVVGGEEARPNSWPWQVSLQYSSNGKWY
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 HFCGGSLISQSWVVTAAHCNVSPGRHFVV-LGEYDRSSNAEPLQVLSVSRAITHPSWNST
: ::::::..:::.::::: .: .: . : ::... ..:::. ..: .:::.
NP_254 HTCGGSLIANSWVLTAAHC-ISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TMN--NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHL
.. ::..:::::.:.. : .:. .:: .. : .. : .::::::. : : : :
NP_254 QISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAV-PDVL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 QQVALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIG
:: : .: : . .::::. ::::::: :. :::.::::::: :: .. : . :
NP_254 QQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHG
180 190 200 210 220 230
240 250 260
pF1KE6 IVSWGTK-NCNV-RAPAVYTRVSKFSTWINQVIAYN
:::.:.. .:: . :.:.::::.. :::.::: :
NP_254 IVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN
240 250 260
>>NP_056933 (OMIM: 609444) chymotrypsin-like elastase fa (269 aa)
initn: 512 init1: 189 opt: 692 Z-score: 857.0 bits: 166.3 E(85289): 5.4e-41
Smith-Waterman score: 692; 42.0% identity (67.5% similar) in 274 aa overlap (2-264:1-269)
10 20 30 40 50
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---F
.. .: :: .. :. .::. . : .: :...::.: .::::::::: ::. .
NP_056 MIRTLLLSTLVAGA-LSCGVSTYAPDMS---RMLGGEEARPNSWPWQVSLQYSSNGQWY
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 HFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTT
: ::::::..:::.::::: : : . :.::... ..:::. ..: .:::
NP_056 HTCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 MN--NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQ
.. ::..:::::.:.. : .:. .:: .. : .. : .::::::. : . : :.
NP_056 VSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAL-PDDLK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 QVALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGI
: : .: : . .:::.. .:::::: :. .:.::::::: :: .. : . ::
NP_056 QGRLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGI
180 190 200 210 220 230
240 250 260
pF1KE6 VSWGTK-NCNVR-APAVYTRVSKFSTWINQVIAYN
: . .:: :...::::... :::.::: :
NP_056 GSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN
240 250 260
>>NP_115780 (OMIM: 605511) transmembrane protease serine (327 aa)
initn: 566 init1: 221 opt: 651 Z-score: 805.3 bits: 157.0 E(85289): 4.1e-38
Smith-Waterman score: 651; 40.8% identity (71.8% similar) in 238 aa overlap (30-259:86-319)
10 20 30 40 50
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHF
.:.:::.:. ..:..::::.::: .:.:.
NP_115 ALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQ-FQGYHL
60 70 80 90 100 110
60 70 80 90 100 110
pF1KE6 CGGSLISQSWVVTAAHCNVS---PGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNST
::::.:. :..::::: . : . .: . .: : .. : . . : ...
NP_115 CGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHL--VEKIVYHSKYKPK
120 130 140 150 160 170
120 130 140 150 160 170
pF1KE6 TMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRL-SGVGNVTPAHLQ
..::..:.:::.: .. :.:::: .:.: . .: .: :.::: .:.:...:. :.
NP_115 RLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPV-LN
180 190 200 210 220 230
180 190 200 210 220 230
pF1KE6 QVALPLVTVNQC--RQYWGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGI
..:.::.. . : :. .:. :. ::.::: .:..:::::::::::::. : :.:
NP_115 HAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGA
240 250 260 270 280 290
240 250 260
pF1KE6 VSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
.:.: .: :.:::::..: ::..
NP_115 TSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT
300 310 320
>>NP_009203 (OMIM: 167800,601405) chymotrypsin-C preprop (268 aa)
initn: 515 init1: 150 opt: 649 Z-score: 804.0 bits: 156.5 E(85289): 4.8e-38
Smith-Waterman score: 649; 39.9% identity (67.2% similar) in 268 aa overlap (3-259:1-264)
10 20 30 40 50
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGF
.:..:. .::. . .::.:.. : : : :.:.::.: :::::.::: ...
NP_009 MLGITVLAALLACASSCGVPSFPPNL--SARVVGGEDARPHSWPWQISLQYLKNDTWR
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 HFCGGSLISQSWVVTAAHCNVSPGRHF-VVLGEYD-RSSNAEPLQVLSVSRAITHPSWNS
: :::.::....:.::::: .: : . :..:. . . . : ..:. .: ::.
NP_009 HTCGGTLIASNFVLTAAHC-ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQ
. ::..:.::: .. . :. .:: .. : . : .:::::: : .. .::
NP_009 LLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIAD-KLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 QVALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGI
: :.: : . .:: . .:.:::: :. :.:.::::::: :: : .: ..::
NP_009 QGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGI
180 190 200 210 220 230
240 250 260
pF1KE6 VSWGTK-NCNVRA-PAVYTRVSKFSTWINQVIAYN
::.:.. .::.: :.:::::: . :::.
NP_009 VSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
240 250 260
>>NP_076927 (OMIM: 605511) transmembrane protease serine (454 aa)
initn: 566 init1: 221 opt: 651 Z-score: 803.3 bits: 157.1 E(85289): 5.3e-38
Smith-Waterman score: 651; 40.8% identity (71.8% similar) in 238 aa overlap (30-259:213-446)
10 20 30 40 50
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHF
.:.:::.:. ..:..::::.::: .:.:.
NP_076 ALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQ-FQGYHL
190 200 210 220 230 240
60 70 80 90 100 110
pF1KE6 CGGSLISQSWVVTAAHCNVS---PGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNST
::::.:. :..::::: . : . .: . .: : .. : . . : ...
NP_076 CGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHL--VEKIVYHSKYKPK
250 260 270 280 290
120 130 140 150 160 170
pF1KE6 TMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRL-SGVGNVTPAHLQ
..::..:.:::.: .. :.:::: .:.: . .: .: :.::: .:.:...:. :.
NP_076 RLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPV-LN
300 310 320 330 340 350
180 190 200 210 220 230
pF1KE6 QVALPLVTVNQC--RQYWGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGI
..:.::.. . : :. .:. :. ::.::: .:..:::::::::::::. : :.:
NP_076 HAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGA
360 370 380 390 400 410
240 250 260
pF1KE6 VSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
.:.: .: :.:::::..: ::..
NP_076 TSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT
420 430 440 450
>>NP_001243246 (OMIM: 605511) transmembrane protease ser (453 aa)
initn: 453 init1: 216 opt: 649 Z-score: 800.8 bits: 156.6 E(85289): 7.2e-38
Smith-Waterman score: 649; 40.5% identity (70.9% similar) in 237 aa overlap (30-259:213-445)
10 20 30 40 50
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHF
.:.:::.:. ..:..::::.::: .:.:.
NP_001 ALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQ-FQGYHL
190 200 210 220 230 240
60 70 80 90 100 110
pF1KE6 CGGSLISQSWVVTAAHCNVS---PGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNST
::::.:. :..::::: . : . .: . .: : .. : . . : ...
NP_001 CGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHL--VEKIVYHSKYKPK
250 260 270 280 290
120 130 140 150 160 170
pF1KE6 TMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ
..::..:.:::.: .. :.:::: .:.: . .: .: :.::: :...:. :..
NP_001 RLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGGDASPV-LNH
300 310 320 330 340 350
180 190 200 210 220 230
pF1KE6 VALPLVTVNQC--RQYWGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGIV
.:.::.. . : :. .:. :. ::.::: .:..:::::::::::::. : :.: .
NP_001 AAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGAT
360 370 380 390 400 410
240 250 260
pF1KE6 SWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
:.: .: :.:::::..: ::..
NP_001 SFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT
420 430 440 450
>>NP_000292 (OMIM: 173350,217090) plasminogen isoform 1 (810 aa)
initn: 533 init1: 209 opt: 633 Z-score: 777.6 bits: 153.2 E(85289): 1.4e-36
Smith-Waterman score: 633; 40.1% identity (65.4% similar) in 257 aa overlap (16-264:564-810)
10 20 30 40
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSW
:. :: : ..: . :.:.: : ::
NP_000 PDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPK-KCPGRVVGGCVAHPHSW
540 550 560 570 580 590
50 60 70 80 90 100
pF1KE6 PWQVSLQDSSGFHFCGGSLISQSWVVTAAHC---NVSPGRHFVVLGEYDRSSNAEP-LQV
::::::. :.:::::.::: ::.::::: . :. . :.:: ... : :: .:
NP_000 PWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEV-NLEPHVQE
600 610 620 630 640 650
110 120 130 140 150 160
pF1KE6 LSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWG
. ::: . .:. .:..::::.::: : .. :.:: : : .... : ::::
NP_000 IEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWG
660 670 680 690 700
170 180 190 200 210
pF1KE6 RLSGVGNVTPAHLQQVALPLVTVNQCRQY--WGSSITDSMICAG--GAGASSCQGDSGGP
. .:. . :... ::.. . : .: .. . .. .::: ..:..:::::::::
NP_000 ETQGT--FGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGP
710 720 730 740 750 760
220 230 240 250 260
pF1KE6 LVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
::: . . ..: :..::: :.::.:::.: :::. :. :
NP_000 LVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
770 780 790 800 810
>>NP_001316119 (OMIM: 118890) chymotrypsinogen B isoform (233 aa)
initn: 608 init1: 357 opt: 626 Z-score: 776.5 bits: 151.2 E(85289): 1.6e-36
Smith-Waterman score: 626; 53.3% identity (80.2% similar) in 167 aa overlap (1-167:1-166)
10 20 30 40 50 60
pF1KE6 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
: : : . :.:...:::.:::.:.:: .::::::.:: :::::::::::..:::::
NP_001 MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
::::::..::::::::.: . :: ::.:..:. : .:::...... .:... :.::
NP_001 GGSLISEDWVVTAAHCGVRTS-DVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNN
70 80 90 100 110
130 140 150 160 170 180
pF1KE6 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
:.::::::.::... .: ::: :... . : :.:::::. . :
NP_001 DITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNGRLWRPPGLPKGWS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
NP_001 LDPGGHCVLGQRHLLHLQPWRVRPCHQAHTLGAEDPGCQLSPRLPPTLLPTEPQ
180 190 200 210 220 230
264 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:36:48 2016 done: Tue Nov 8 11:36:50 2016
Total Scan time: 7.050 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]