Result of FASTA (ccds) for
pFN21AE6257
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6257, 247 aa
1>>>pF1KE6257 247 - 247 aa - 247 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5338+/-0.000919; mu= 12.6656+/- 0.055
mean_var=63.4571+/-13.358, 0's: 0 Z-trim(104.4): 19 B-trim: 0 in 0/52
Lambda= 0.161003
statistics sampled from 7853 (7859) to 7853 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.241), width: 16
Scan time: 1.400
The best scores are: opt bits E(32554)
CCDS41391.1 APH1A gene_id:51107|Hs108|chr1 ( 247) 1609 382.5 1.4e-106
CCDS41390.1 APH1A gene_id:51107|Hs108|chr1 ( 265) 1598 379.9 9e-106
CCDS10184.1 APH1B gene_id:83464|Hs108|chr15 ( 257) 1005 242.2 2.5e-64
CCDS58025.1 APH1A gene_id:51107|Hs108|chr1 ( 195) 837 203.1 1.1e-52
CCDS45276.1 APH1B gene_id:83464|Hs108|chr15 ( 216) 486 121.6 4.2e-28
>>CCDS41391.1 APH1A gene_id:51107|Hs108|chr1 (247 aa)
initn: 1609 init1: 1609 opt: 1609 Z-score: 2026.7 bits: 382.5 E(32554): 1.4e-106
Smith-Waterman score: 1609; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)
10 20 30 40 50 60
pF1KE6 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
190 200 210 220 230 240
pF1KE6 RSLLCKD
:::::::
CCDS41 RSLLCKD
>>CCDS41390.1 APH1A gene_id:51107|Hs108|chr1 (265 aa)
initn: 1598 init1: 1598 opt: 1598 Z-score: 2012.4 bits: 379.9 E(32554): 9e-106
Smith-Waterman score: 1598; 99.6% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KE6 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
190 200 210 220 230 240
pF1KE6 RSLLCKD
:::::.
CCDS41 RSLLCRRQEDSRVMVYSALRIPPED
250 260
>>CCDS10184.1 APH1B gene_id:83464|Hs108|chr15 (257 aa)
initn: 978 init1: 536 opt: 1005 Z-score: 1268.2 bits: 242.2 E(32554): 2.5e-64
Smith-Waterman score: 1005; 59.1% identity (83.0% similar) in 247 aa overlap (1-247:1-246)
10 20 30 40 50 60
pF1KE6 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
: :::::::.:.:::::.::...:.: .:::.:.:.:::::::::::..:.:::. .
CCDS10 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
: .:. : :::::: ::: .::.::::::::::::.::: :.. :.. :.: .:::
CCDS10 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINP-GETAPSMRLLAYV
70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
:::.:::.::::: .: :.:.::::.:::::::: .:: :::.: .:::::.:::.::::
CCDS10 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
.::.... : .:. .:::.:. ::.. .: .: . . : :: :::..:::: ::..
CCDS10 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK
180 190 200 210 220 230
pF1KE6 RSLLCKD
:::.:
CCDS10 LCLLCQDKNFLLYNQRSR
240 250
>>CCDS58025.1 APH1A gene_id:51107|Hs108|chr1 (195 aa)
initn: 1071 init1: 837 opt: 837 Z-score: 1059.3 bits: 203.1 E(32554): 1.1e-52
Smith-Waterman score: 933; 67.9% identity (69.5% similar) in 246 aa overlap (1-246:1-176)
10 20 30 40 50 60
pF1KE6 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
::::::::::::::::::::::::::::::::::::::
CCDS58 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAG----------------------
10 20 30
70 80 90 100 110 120
pF1KE6 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
: .: : . : .
CCDS58 -RCSA-----------------------------------LPTTS------------CLI
40 50
130 140 150 160 170 180
pF1KE6 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE6 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
120 130 140 150 160 170
pF1KE6 RSLLCKD
:::::.
CCDS58 RSLLCRRQEDSRVMVYSALRIPPED
180 190
>>CCDS45276.1 APH1B gene_id:83464|Hs108|chr15 (216 aa)
initn: 771 init1: 456 opt: 486 Z-score: 617.9 bits: 121.6 E(32554): 4.2e-28
Smith-Waterman score: 703; 47.0% identity (68.0% similar) in 247 aa overlap (1-247:1-205)
10 20 30 40 50 60
pF1KE6 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
: :::::::.:.:::::.::...:.: .:::.:.:.:::::::::::..:.:::. .
CCDS45 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
: .:. : :::::: ::: .::.::::::::::::.::: :.. :.. :.: .::
CCDS45 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINP-GETAPSMRLLAY-
70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
::.: .:::::.:::.::::
CCDS45 ----------------------------------------AFMTLVIILLHVFWGIVFFD
120 130
190 200 210 220 230 240
pF1KE6 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
.::.... : .:. .:::.:. ::.. .: .: . . : :: :::..:::: ::..
CCDS45 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK
140 150 160 170 180 190
pF1KE6 RSLLCKD
:::.:
CCDS45 LCLLCQDKNFLLYNQRSR
200 210
247 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:32:33 2016 done: Tue Nov 8 11:32:33 2016
Total Scan time: 1.400 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]