FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6255, 226 aa
  1>>>pF1KE6255 226 - 226 aa - 226 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2791+/-0.000494; mu= 5.0831+/- 0.031
 mean_var=123.0668+/-24.787, 0's: 0 Z-trim(111.7): 6  B-trim: 745 in 1/53
 Lambda= 0.115612
 statistics sampled from 20357 (20361) to 20357 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.239), width:  16
 Scan time:  4.510

The best scores are:                                      opt bits E(85289)
NP_001687 (OMIM: 108746) V-type proton ATPase subu ( 226) 1080 191.2 1.2e-48
NP_001034455 (OMIM: 108746) V-type proton ATPase s ( 204)  898 160.9 1.5e-39
NP_001034456 (OMIM: 108746) V-type proton ATPase s ( 196)  523 98.3 9.6e-21


>>NP_001687 (OMIM: 108746) V-type proton ATPase subunit   (226 aa)
 initn: 1097 init1: 1080 opt: 1080  Z-score: 994.6  bits: 191.2 E(85289): 1.2e-48
Smith-Waterman score: 1080; 76.4% identity (89.3% similar) in 225 aa overlap (1-225:1-225)

               10        20        30        40        50        60
pF1KE6 MALRDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK
       ::: :.::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 EKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLV
       :::::::::: ::.. :::::::::::.:::.:::.::: :::..:.:   :: ::: ::
NP_001 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGG
       :::: .:::: :::::: ::. ::.:::::::: :   ... :.::::.:.::  . :::
NP_001 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG
              130       140       150       160       170       180

              190       200       210       220      
pF1KE6 VEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI
       ::.:.:...::::::::::::: :.: :::.: ::::::.::::. 
NP_001 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
              190       200       210       220      

>>NP_001034455 (OMIM: 108746) V-type proton ATPase subun  (204 aa)
 initn: 955 init1: 891 opt: 898  Z-score: 831.2  bits: 160.9 E(85289): 1.5e-39
Smith-Waterman score: 898; 72.1% identity (87.8% similar) in 197 aa overlap (29-225:7-203)

               10        20        30        40        50        60
pF1KE6 MALRDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK
                                   ... .:::::::::::::::::::::::::::
NP_001                       MALSDADVQKQAEEEFNIEKGRLVQTQRLKIMEYYEKK
                                     10        20        30        

               70        80        90       100       110       120
pF1KE6 EKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLV
       :::::::::: ::.. :::::::::::.:::.:::.::: :::..:.:   :: ::: ::
NP_001 EKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLV
       40        50        60        70        80        90        

              130       140       150       160       170       180
pF1KE6 LQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGG
       :::: .:::: :::::: ::. ::.:::::::: :   ... :.::::.:.::  . :::
NP_001 LQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG
      100       110       120       130       140       150        

              190       200       210       220      
pF1KE6 VEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI
       ::.:.:...::::::::::::: :.: :::.: ::::::.::::. 
NP_001 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
      160       170       180       190       200    

>>NP_001034456 (OMIM: 108746) V-type proton ATPase subun  (196 aa)
 initn: 954 init1: 522 opt: 523  Z-score: 493.4  bits: 98.3 E(85289): 9.6e-21
Smith-Waterman score: 894; 67.6% identity (78.7% similar) in 225 aa overlap (1-225:1-195)

               10        20        30        40        50        60
pF1KE6 MALRDVDVKKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK
       ::: :.::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 EKQIEQQKKILMSTMRNQARLKVLRARNDLISDLLSEAKLRLSRIVEDPEVYQGLLDKLV
       :::::::::: ::.. :::::::::::.:::.                            
NP_001 EKQIEQQKKIQMSNLMNQARLKVLRARDDLIT----------------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KE6 LQGLLRLLEPVMIVRCRPQDLLLVEAAVQKAIPEYMTISQKHVEVQIDKEAYLAVNAAGG
         :: .:::: :::::: ::. ::.:::::::: :   ... :.::::.:.::  . :::
NP_001 --GLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGG
              100       110       120       130       140       150

              190       200       210       220      
pF1KE6 VEVYSGNQRIKVSNTLESRLDLSAKQKMPEIRMALFGANTNRKFFI
       ::.:.:...::::::::::::: :.: :::.: ::::::.::::. 
NP_001 VEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
              160       170       180       190      




226 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 11:30:57 2016 done: Tue Nov  8 11:30:58 2016
 Total Scan time:  4.510 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]