Result of FASTA (omim) for
pFN21AE6244
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6244, 278 aa
1>>>pF1KE6244 278 - 278 aa - 278 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7898+/-0.00038; mu= 17.2876+/- 0.023
mean_var=58.0017+/-12.086, 0's: 0 Z-trim(111.0): 52 B-trim: 1325 in 1/57
Lambda= 0.168405
statistics sampled from 19495 (19544) to 19495 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.229), width: 16
Scan time: 5.280
The best scores are: opt bits E(85289)
NP_006403 (OMIM: 603100,608594) 1-acyl-sn-glycerol ( 278) 1822 451.1 1e-126
NP_001012745 (OMIM: 603100,608594) 1-acyl-sn-glyce ( 246) 1092 273.7 2.3e-73
XP_011512536 (OMIM: 603099) PREDICTED: 1-acyl-sn-g ( 283) 832 210.6 2.7e-54
NP_006402 (OMIM: 603099) 1-acyl-sn-glycerol-3-phos ( 283) 832 210.6 2.7e-54
XP_005248863 (OMIM: 603099) PREDICTED: 1-acyl-sn-g ( 283) 832 210.6 2.7e-54
NP_116130 (OMIM: 603099) 1-acyl-sn-glycerol-3-phos ( 283) 832 210.6 2.7e-54
XP_005248862 (OMIM: 603099) PREDICTED: 1-acyl-sn-g ( 287) 832 210.6 2.7e-54
XP_006720517 (OMIM: 612039) PREDICTED: lysophospho ( 409) 168 49.4 1.3e-05
NP_705841 (OMIM: 612039) lysophospholipid acyltran ( 524) 168 49.4 1.6e-05
>>NP_006403 (OMIM: 603100,608594) 1-acyl-sn-glycerol-3-p (278 aa)
initn: 1822 init1: 1822 opt: 1822 Z-score: 2395.8 bits: 451.1 E(85289): 1e-126
Smith-Waterman score: 1822; 99.6% identity (99.6% similar) in 278 aa overlap (1-278:1-278)
10 20 30 40 50 60
pF1KE6 MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_006 LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
190 200 210 220 230 240
250 260 270
pF1KE6 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
::::::::::::::::::::::::::::::::::::::
NP_006 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
250 260 270
>>NP_001012745 (OMIM: 603100,608594) 1-acyl-sn-glycerol- (246 aa)
initn: 1106 init1: 1087 opt: 1092 Z-score: 1438.0 bits: 273.7 E(85289): 2.3e-73
Smith-Waterman score: 1527; 88.1% identity (88.1% similar) in 278 aa overlap (1-278:1-246)
10 20 30 40 50 60
pF1KE6 MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
::::::::::::::::::::::::::::::::::::::::::::
NP_001 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVREN----------------
130 140 150 160
190 200 210 220 230 240
pF1KE6 LLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
::: ::::::::::::::::::::::::::::::::::::::::
NP_001 ----------------VPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
170 180 190 200
250 260 270
pF1KE6 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
::::::::::::::::::::::::::::::::::::::
NP_001 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
210 220 230 240
>>XP_011512536 (OMIM: 603099) PREDICTED: 1-acyl-sn-glyce (283 aa)
initn: 851 init1: 758 opt: 832 Z-score: 1095.7 bits: 210.6 E(85289): 2.7e-54
Smith-Waterman score: 832; 47.3% identity (76.0% similar) in 275 aa overlap (1-267:1-273)
10 20 30 40 50
pF1KE6 MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH
:.::: ::::.::. . : .:... :.:.: . . ....: :: .:
XP_011 MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR-
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP
::.::::.:. .. .::.::.: ::: ... ..: :.:::::: ::..:.:::::
XP_011 -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPE
::: :::::::. : .:: .:.::.::.:.:.. :..::..... .. ....::..::
XP_011 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 GTRNDNGDLLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP
:::: ::..::::.:::.::::::::: :.:.::...:: :.. :::: :.:: .:
XP_011 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP
180 190 200 210 220 230
240 250 260 270
pF1KE6 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
: ::: :::::.: ...: :.: .:: . .:
XP_011 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
240 250 260 270 280
>>NP_006402 (OMIM: 603099) 1-acyl-sn-glycerol-3-phosphat (283 aa)
initn: 851 init1: 758 opt: 832 Z-score: 1095.7 bits: 210.6 E(85289): 2.7e-54
Smith-Waterman score: 832; 47.3% identity (76.0% similar) in 275 aa overlap (1-267:1-273)
10 20 30 40 50
pF1KE6 MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH
:.::: ::::.::. . : .:... :.:.: . . ....: :: .:
NP_006 MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR-
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP
::.::::.:. .. .::.::.: ::: ... ..: :.:::::: ::..:.:::::
NP_006 -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPE
::: :::::::. : .:: .:.::.::.:.:.. :..::..... .. ....::..::
NP_006 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 GTRNDNGDLLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP
:::: ::..::::.:::.::::::::: :.:.::...:: :.. :::: :.:: .:
NP_006 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP
180 190 200 210 220 230
240 250 260 270
pF1KE6 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
: ::: :::::.: ...: :.: .:: . .:
NP_006 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
240 250 260 270 280
>>XP_005248863 (OMIM: 603099) PREDICTED: 1-acyl-sn-glyce (283 aa)
initn: 851 init1: 758 opt: 832 Z-score: 1095.7 bits: 210.6 E(85289): 2.7e-54
Smith-Waterman score: 832; 47.3% identity (76.0% similar) in 275 aa overlap (1-267:1-273)
10 20 30 40 50
pF1KE6 MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH
:.::: ::::.::. . : .:... :.:.: . . ....: :: .:
XP_005 MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR-
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP
::.::::.:. .. .::.::.: ::: ... ..: :.:::::: ::..:.:::::
XP_005 -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPE
::: :::::::. : .:: .:.::.::.:.:.. :..::..... .. ....::..::
XP_005 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 GTRNDNGDLLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP
:::: ::..::::.:::.::::::::: :.:.::...:: :.. :::: :.:: .:
XP_005 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP
180 190 200 210 220 230
240 250 260 270
pF1KE6 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
: ::: :::::.: ...: :.: .:: . .:
XP_005 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
240 250 260 270 280
>>NP_116130 (OMIM: 603099) 1-acyl-sn-glycerol-3-phosphat (283 aa)
initn: 851 init1: 758 opt: 832 Z-score: 1095.7 bits: 210.6 E(85289): 2.7e-54
Smith-Waterman score: 832; 47.3% identity (76.0% similar) in 275 aa overlap (1-267:1-273)
10 20 30 40 50
pF1KE6 MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH
:.::: ::::.::. . : .:... :.:.: . . ....: :: .:
NP_116 MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR-
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP
::.::::.:. .. .::.::.: ::: ... ..: :.:::::: ::..:.:::::
NP_116 -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPE
::: :::::::. : .:: .:.::.::.:.:.. :..::..... .. ....::..::
NP_116 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 GTRNDNGDLLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP
:::: ::..::::.:::.::::::::: :.:.::...:: :.. :::: :.:: .:
NP_116 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP
180 190 200 210 220 230
240 250 260 270
pF1KE6 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
: ::: :::::.: ...: :.: .:: . .:
NP_116 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
240 250 260 270 280
>>XP_005248862 (OMIM: 603099) PREDICTED: 1-acyl-sn-glyce (287 aa)
initn: 851 init1: 758 opt: 832 Z-score: 1095.6 bits: 210.6 E(85289): 2.7e-54
Smith-Waterman score: 832; 47.3% identity (76.0% similar) in 275 aa overlap (1-267:5-277)
10 20 30 40
pF1KE6 MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVC
:.::: ::::.::. . : .:... :.:.: . . ....: ::
XP_005 MVARMDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLM
.: ::.::::.:. .. .::.::.: ::: ... ..: :.:::::: ::..:.:
XP_005 AVR--GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMM
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 EVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVW
:::: ::: :::::::. : .:: .:.::.::.:.:.. :..::..... .. ....::
XP_005 EVLPGRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVW
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 IYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIFPVVYSSFSSFYNTKKKFFTSGTVTVQVL
..:::::: ::..::::.:::.::::::::: :.:.::...:: :.. :::: :.::
XP_005 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVL
180 190 200 210 220 230
230 240 250 260 270
pF1KE6 EAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
.:: ::: :::::.: ...: :.: .:: . .:
XP_005 PPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
240 250 260 270 280
>>XP_006720517 (OMIM: 612039) PREDICTED: lysophospholipi (409 aa)
initn: 75 init1: 75 opt: 168 Z-score: 221.6 bits: 49.4 E(85289): 1.3e-05
Smith-Waterman score: 168; 25.0% identity (58.9% similar) in 180 aa overlap (55-230:86-257)
30 40 50 60 70 80
pF1KE6 EFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYG-LRFEVRDP
.:: . ...: . : . .. : ::..::
XP_006 IVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLG-LSRLLFFLLGFLRIRVRGQ
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE6 RRLQEARPCVIVSNHQSILDMMGLMEV-LPERCVQIAKRELLFLGPVGLIMYLGGVFFIN
: . : .... :....: . :. ::. ... : : . .: .. .. .....
XP_006 RASRLQAPVLVAAPHSTFFDPIVLLPCDLPKV---VSRAENLSVPVIGALLRFNQAILVS
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE6 RQRSSTAMTVMADLGERMVRENL--KVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIF
:. .. :. .. .: . . .: ..:::: ... :: :: ::: : ::.
XP_006 RHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFI----AGVPVQ
180 190 200 210 220
210 220 230 240 250 260
pF1KE6 PVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHIS
::. .:. .:. . :.. : : :
XP_006 PVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYAN
230 240 250 260 270 280
>>NP_705841 (OMIM: 612039) lysophospholipid acyltransfer (524 aa)
initn: 75 init1: 75 opt: 168 Z-score: 220.0 bits: 49.4 E(85289): 1.6e-05
Smith-Waterman score: 168; 25.0% identity (58.9% similar) in 180 aa overlap (55-230:86-257)
30 40 50 60 70 80
pF1KE6 EFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYG-LRFEVRDP
.:: . ...: . : . .. : ::..::
NP_705 IVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLG-LSRLLFFLLGFLRIRVRGQ
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE6 RRLQEARPCVIVSNHQSILDMMGLMEV-LPERCVQIAKRELLFLGPVGLIMYLGGVFFIN
: . : .... :....: . :. ::. ... : : . .: .. .. .....
NP_705 RASRLQAPVLVAAPHSTFFDPIVLLPCDLPKV---VSRAENLSVPVIGALLRFNQAILVS
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE6 RQRSSTAMTVMADLGERMVRENL--KVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIF
:. .. :. .. .: . . .: ..:::: ... :: :: ::: : ::.
NP_705 RHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFI----AGVPVQ
180 190 200 210 220
210 220 230 240 250 260
pF1KE6 PVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHIS
::. .:. .:. . :.. : : :
NP_705 PVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYAN
230 240 250 260 270 280
278 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:24:35 2016 done: Tue Nov 8 11:24:36 2016
Total Scan time: 5.280 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]