Result of FASTA (ccds) for
pFN21AE6233
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6233, 291 aa
1>>>pF1KE6233 291 - 291 aa - 291 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1411+/-0.000814; mu= 16.3706+/- 0.049
mean_var=62.4086+/-12.783, 0's: 0 Z-trim(107.5): 17 B-trim: 242 in 1/51
Lambda= 0.162350
statistics sampled from 9593 (9600) to 9593 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.295), width: 16
Scan time: 1.550
The best scores are: opt bits E(32554)
CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 ( 291) 2032 484.2 4.7e-137
CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 ( 290) 785 192.2 3.9e-49
CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX ( 357) 679 167.4 1.4e-41
CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX ( 353) 618 153.1 2.7e-37
CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 ( 279) 457 115.3 5.1e-26
CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 ( 303) 389 99.4 3.4e-21
>>CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 (291 aa)
initn: 2032 init1: 2032 opt: 2032 Z-score: 2574.1 bits: 484.2 E(32554): 4.7e-137
Smith-Waterman score: 2032; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KE6 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 IKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPH
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 YSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 YSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
250 260 270 280 290
>>CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 (290 aa)
initn: 704 init1: 314 opt: 785 Z-score: 995.6 bits: 192.2 E(32554): 3.9e-49
Smith-Waterman score: 785; 39.2% identity (73.0% similar) in 296 aa overlap (1-291:1-289)
10 20 30 40 50 60
pF1KE6 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
:. .:::.::: .::.... ::: : :..::: . :..: :.:..:: .:..:.: ..
CCDS32 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
:..:::. .:: :::.: .::. .:: . ..:... ::::...: . .: :. :: :
CCDS32 VMLQTVSDHTPKYQDRLATPGLMIRPKT---ENLDVIVNVSDTESWDQHVQKLNKFLEPY
70 80 90 100 110
130 140 150 160 170
pF1KE6 SPA--AQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADP-NFGFEEGKP
. . ::.... : .:. : . . :. : .:.:. .: ::::..: ..:. :.:
CCDS32 NDSIQAQKNDV-CRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 CFIIKMNRIVKFLPSNGSAPRVDCAFL-DQPRE-LGQPLQVKYYPPNGTFSLHYFPYYGK
: .:::::...: . ... : :: :. : ::. .. .: ::...: :::::::
CCDS32 CVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVM---FPANGNIDLMYFPYYGK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 KAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
: . .:..::::.:.::. :.:: . :.. : ... .. .: . :.: :::.:.:
CCDS32 KFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
240 250 260 270 280 290
>>CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX (357 aa)
initn: 602 init1: 210 opt: 679 Z-score: 860.1 bits: 167.4 E(32554): 1.4e-41
Smith-Waterman score: 679; 35.4% identity (70.4% similar) in 280 aa overlap (12-290:84-356)
10 20 30 40
pF1KE6 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWIS
:... ...: :.:. ..:.:: . : :
CCDS48 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLIL
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE6 LYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVS
: : ::. ......::.:.:. :..:: : . .... ::: .:: .. .:.. .:::
CCDS48 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAH---SLNFNFNVS
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE6 DNRTWADLTQTLHAFLAGYSPAAQED-SINCTSEQYFFQESFRAPNHTKFSCKFTADMLQ
. :: . .:..:: ::. . ::. ...: :::.:.. .. : .:.: ..:.
CCDS48 EPDTWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQDG--NEDEDKKACQFKRSFLK
180 190 200 210 220
170 180 190 200 210 220
pF1KE6 NCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYP
::::: ::.::. :.::...:::::: : : :. .:.: : . .. ...:::
CCDS48 NCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKV--QRGDENDIRSISYYP
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 PNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYE
...:.:.:.::::: .. .:..:::: .. .. .: : . :.. .. : . .: .
CCDS48 ESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFV
290 300 310 320 330 340
290
pF1KE6 GKVEFKLKIEK
:.: : :.::
CCDS48 GRVIFTLNIET
350
>>CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX (353 aa)
initn: 537 init1: 195 opt: 618 Z-score: 782.9 bits: 153.1 E(32554): 2.7e-37
Smith-Waterman score: 649; 35.0% identity (69.6% similar) in 280 aa overlap (12-290:84-352)
10 20 30 40
pF1KE6 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWIS
:... ...: :.:. ..:.:: :
CCDS14 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTG----LIL
60 70 80 90 100
50 60 70 80 90 100
pF1KE6 LYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVS
: : ::. ......::.:.:. :..:: : . .... ::: .:: .. .:.. .:::
CCDS14 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAH---SLNFNFNVS
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE6 DNRTWADLTQTLHAFLAGYSPAAQED-SINCTSEQYFFQESFRAPNHTKFSCKFTADMLQ
. :: . .:..:: ::. . ::. ...: :::.:.. .. : .:.: ..:.
CCDS14 EPDTWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQDG--NEDEDKKACQFKRSFLK
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE6 NCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYP
::::: ::.::. :.::...:::::: : : :. .:.: : . .. ...:::
CCDS14 NCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKV--QRGDENDIRSISYYP
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 PNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYE
...:.:.:.::::: .. .:..:::: .. .. .: : . :.. .. : . .: .
CCDS14 ESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFV
290 300 310 320 330 340
290
pF1KE6 GKVEFKLKIEK
:.: : :.::
CCDS14 GRVIFTLNIET
350
>>CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 (279 aa)
initn: 580 init1: 237 opt: 457 Z-score: 580.6 bits: 115.3 E(32554): 5.1e-26
Smith-Waterman score: 632; 35.4% identity (66.0% similar) in 285 aa overlap (6-287:5-275)
10 20 30 40 50 60
pF1KE6 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
:::. .: . :.. . .:: ::..:::: . : : :.:..:: ...::.. ..
CCDS31 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMW
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
:..::.. .: :.::. :::. . : .:: ... :: ..: . :. :: :
CCDS31 VMLQTLNDEVPKYRDQIPSPGLMVFPKPV--TALEYTFSRSDPTSYAGYIEDLKKFLKPY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFI
. :.. : . : : ..: .. .:.: ..:: :::. ::.::. .:.::..
CCDS31 TLEEQKNLTVCPDGALFEQ---KGPVYV--ACQFPISLLQACSGMNDPDFGYSQGNPCIL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 IKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPH
.:::::. . : . .::.::. .. : .: :: :: ..:.:::::::: .
CCDS31 VKMNRIIGLKPEG--VPRIDCV----SKNEDIP-NVAVYPHNGMIDLKYFPYYGKKLHVG
180 190 200 210 220
250 260 270 280 290
pF1KE6 YSNPLVAAKLLNIPRNA--EVAIVCKV-MAEHVTFNNPHDPYEGKVEFKLKIEK
: .::::... : :. ::.. ::. . .. .. .: . :.: ::.
CCDS31 YLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
230 240 250 260 270
>>CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 (303 aa)
initn: 477 init1: 194 opt: 389 Z-score: 494.0 bits: 99.4 E(32554): 3.4e-21
Smith-Waterman score: 522; 30.1% identity (61.8% similar) in 306 aa overlap (11-290:4-302)
10 20 30 40 50
pF1KE6 MAALQEKKTCGQRMEE--FQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALC
:. :: .... :: . ..:::: . : : :.:: :: ..:.:
CCDS12 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGT
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLA
. :.. :.. . : :::.. ::.: :.. . :: . .: ... . .. ::
CCDS12 IQVMLLTISEFKPTYQDRVAPPGLTQIPQI---QKTEISFRPNDPKSYEAYVLNIVRFLE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 GYSPAAQEDSI---NCTSEQYFFQE--SFRAPNHTKFSCKFTADMLQNCSGLADPNFGFE
:. .::.:.. .: . .: .: . :.: . : ::::: : ..:..
CCDS12 KYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYK
120 130 140 150 160 170
180 190 200 210
pF1KE6 EGKPCFIIKMNRIVKFLPS---------------NGSAPRVDCAFL-DQPRE-LGQPLQV
:::::.:::.::.. : :. : .. :.:. :. .. .:. :
CCDS12 EGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGN---V
180 190 200 210 220
220 230 240 250 260 270
pF1KE6 KYYPPNGT--FSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNN
.:. ... : :.:.::::: ::.: .::.:... :. ..:. : ::...:.. ...
CCDS12 EYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSE
230 240 250 260 270 280
280 290
pF1KE6 PHDPYEGKVEFKLKIEK
.: ..:. . :....
CCDS12 -KDRFQGRFDVKIEVKS
290 300
291 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:19:08 2016 done: Tue Nov 8 11:19:09 2016
Total Scan time: 1.550 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]