Result of FASTA (ccds) for
pFN21AE6231
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6231, 248 aa
1>>>pF1KE6231 248 - 248 aa - 248 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8548+/-0.000896; mu= 16.7765+/- 0.054
mean_var=60.1070+/-12.277, 0's: 0 Z-trim(104.5): 33 B-trim: 0 in 0/52
Lambda= 0.165429
statistics sampled from 7887 (7919) to 7887 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.243), width: 16
Scan time: 2.250
The best scores are: opt bits E(32554)
CCDS7981.1 MS4A6A gene_id:64231|Hs108|chr11 ( 248) 1581 385.7 1.5e-107
CCDS81568.1 MS4A6A gene_id:64231|Hs108|chr11 ( 276) 1581 385.7 1.7e-107
CCDS44615.1 MS4A6A gene_id:64231|Hs108|chr11 ( 225) 1376 336.8 7.7e-93
CCDS58134.1 MS4A6A gene_id:64231|Hs108|chr11 ( 253) 1376 336.8 8.4e-93
CCDS44616.1 MS4A6A gene_id:64231|Hs108|chr11 ( 178) 912 226.0 1.4e-59
CCDS7985.1 MS4A7 gene_id:58475|Hs108|chr11 ( 240) 446 114.8 5.3e-26
CCDS7984.1 MS4A6E gene_id:245802|Hs108|chr11 ( 147) 293 78.2 3.5e-15
CCDS7986.1 MS4A7 gene_id:58475|Hs108|chr11 ( 195) 250 68.0 5.4e-12
CCDS7987.1 MS4A5 gene_id:64232|Hs108|chr11 ( 200) 235 64.4 6.6e-11
>>CCDS7981.1 MS4A6A gene_id:64231|Hs108|chr11 (248 aa)
initn: 1581 init1: 1581 opt: 1581 Z-score: 2044.1 bits: 385.7 E(32554): 1.5e-107
Smith-Waterman score: 1581; 99.6% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLAGSLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDC
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDC
190 200 210 220 230 240
pF1KE6 GYEELLTS
::::::::
CCDS79 GYEELLTS
>>CCDS81568.1 MS4A6A gene_id:64231|Hs108|chr11 (276 aa)
initn: 1581 init1: 1581 opt: 1581 Z-score: 2043.4 bits: 385.7 E(32554): 1.7e-107
Smith-Waterman score: 1581; 99.6% identity (100.0% similar) in 248 aa overlap (1-248:29-276)
10 20 30
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQ
::::::::::::::::::::::::::::::::
CCDS81 MVLLKLLEVYRKGSAGTFHKSTIFGNTIMTSQPVPNETIIVLPSNVINFSQAEKPEPTNQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 GQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 KNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGSLSLMLICTLLEFCLAVLTAVLRWKQAY
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
CCDS81 KNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAY
190 200 210 220 230 240
220 230 240
pF1KE6 SDFPGSVLFLPHSYIGNSGMSSKMTHDCGYEELLTS
::::::::::::::::::::::::::::::::::::
CCDS81 SDFPGSVLFLPHSYIGNSGMSSKMTHDCGYEELLTS
250 260 270
>>CCDS44615.1 MS4A6A gene_id:64231|Hs108|chr11 (225 aa)
initn: 1373 init1: 1373 opt: 1376 Z-score: 1780.3 bits: 336.8 E(32554): 7.7e-93
Smith-Waterman score: 1376; 99.1% identity (99.5% similar) in 221 aa overlap (1-220:1-221)
10 20 30 40 50 60
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 SLAGSLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG-SVLFLPHSYIGNSGMSSKMTHD
::::.:::::::::::::::::::::::::::::::: :::
CCDS44 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGVSVLAGFT
190 200 210 220
240
pF1KE6 CGYEELLTS
>>CCDS58134.1 MS4A6A gene_id:64231|Hs108|chr11 (253 aa)
initn: 1373 init1: 1373 opt: 1376 Z-score: 1779.6 bits: 336.8 E(32554): 8.4e-93
Smith-Waterman score: 1376; 99.1% identity (99.5% similar) in 221 aa overlap (1-220:29-249)
10 20 30
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQ
::::::::::::::::::::::::::::::::
CCDS58 MVLLKLLEVYRKGSAGTFHKSTIFGNTIMTSQPVPNETIIVLPSNVINFSQAEKPEPTNQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 GQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 KNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGSLSLMLICTLLEFCLAVLTAVLRWKQAY
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
CCDS58 KNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAY
190 200 210 220 230 240
220 230 240
pF1KE6 SDFPG-SVLFLPHSYIGNSGMSSKMTHDCGYEELLTS
::::: :::
CCDS58 SDFPGVSVLAGFT
250
>>CCDS44616.1 MS4A6A gene_id:64231|Hs108|chr11 (178 aa)
initn: 912 init1: 912 opt: 912 Z-score: 1183.3 bits: 226.0 E(32554): 1.4e-59
Smith-Waterman score: 912; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148)
10 20 30 40 50 60
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
::::::::::::::::::::::::::::
CCDS44 SILSALSALVGFIILSVKQATLNPASLQWNSLSDADLHSAGILPSCAHCCAAVETGLL
130 140 150 160 170
>>CCDS7985.1 MS4A7 gene_id:58475|Hs108|chr11 (240 aa)
initn: 448 init1: 293 opt: 446 Z-score: 580.3 bits: 114.8 E(32554): 5.3e-26
Smith-Waterman score: 446; 39.8% identity (69.2% similar) in 201 aa overlap (19-218:19-217)
10 20 30 40 50 60
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
:.. : ::: :..: :.. : .: :.::.:::: ...
CCDS79 MLLQSQTMGVSHSFTPKGITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
::: ::. : . .:. . :: : :.:::.: . : :.::::: . :. :: . :::..
CCDS79 SLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTS
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTT-DCYTAK
. .:...: .:...:. ....: :: .: . . . . : :.: .: :: ..
CCDS79 NAVSSVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTS
130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ASLAGSLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHD
.::.: : .::: :.::. ::. ..:. ::: ::. :::
CCDS79 VSLTGVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRS
180 190 200 210 220 230
240
pF1KE6 CGYEELLTS
CCDS79 WI
240
>>CCDS7984.1 MS4A6E gene_id:245802|Hs108|chr11 (147 aa)
initn: 512 init1: 277 opt: 293 Z-score: 386.1 bits: 78.2 E(32554): 3.5e-15
Smith-Waterman score: 594; 55.2% identity (64.8% similar) in 210 aa overlap (1-210:1-145)
10 20 30 40 50 60
pF1KE6 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
:::::. :::::.::::::::::::::::::::::::::.:.:..::::
CCDS79 MTSQPISNETIIMLPSNVINFSQAEKPEPTNQGQDSLKKRLQAKVKVIG-----------
10 20 30 40
70 80 90 100 110 120
pF1KE6 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
:::::.:
CCDS79 -----------------------------------------------------VHSSLAG
50
130 140 150 160 170 180
pF1KE6 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
:::::::::::::.:::. :.::::::::.::...:::: .:: :: : :: ::. :::
CCDS79 SILSALSALVGFILLSVNPAALNPASLQCKLDEKDIPTRLLLSYDYH-SPYTMDCHRAKA
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE6 SLAGSLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDC
::::.:::::. :.::::::::::::.:::
CCDS79 SLAGTLSLMLVSTVLEFCLAVLTAVLQWKQTV
120 130 140
>>CCDS7986.1 MS4A7 gene_id:58475|Hs108|chr11 (195 aa)
initn: 243 init1: 145 opt: 250 Z-score: 328.8 bits: 68.0 E(32554): 5.4e-12
Smith-Waterman score: 250; 38.4% identity (69.6% similar) in 125 aa overlap (95-218:50-172)
70 80 90 100 110 120
pF1KE6 ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS
: :.::::: . :. :: . :::... .:
CCDS79 TIPQREKPGHMYQNEDYLQNGLPTETTVLGFGITGSLSIISGKQSTKPFDLSSLTSNAVS
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE6 ALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTT-DCYTAKASLA
...: .:...:. ....: :: .: . . . . : :.: .: :: ...::.
CCDS79 SVTAGAGLFLLADSMVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLT
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE6 GSLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDCGYE
: : .::: :.::. ::. ..:. ::: ::. :::
CCDS79 GVLVVMLIFTVLELLLAAYSSVFWWKQLYSNNPGSSFSSTQSQDHIQQVKKSSSRSWI
140 150 160 170 180 190
pF1KE6 ELLTS
>>CCDS7987.1 MS4A5 gene_id:64232|Hs108|chr11 (200 aa)
initn: 194 init1: 133 opt: 235 Z-score: 309.3 bits: 64.4 E(32554): 6.6e-11
Smith-Waterman score: 239; 26.4% identity (62.5% similar) in 208 aa overlap (1-206:1-187)
10 20 30 40 50
pF1KE6 MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM
: :. . . ...:.: .. .. ..: : . :. :.: . ..:..:::::: :.:
CCDS79 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL
..:.:.:. . ..: . . .: :.::: : .:: ::.. ::.... :. :. :
CCDS79 TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTA
. ..::::.:..:.:.:. . ::.: :. . :.. ..: ..
CCDS79 IMNFLSALGAIAGIILLT----------FGFILDQN------YICGYSHQN---SQCKAV
120 130 140 150
180 190 200 210 220 230
pF1KE6 KASLAGSLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTH
. . : : .. ...:. ... ..:
CCDS79 TVLFLGILITLMTFSIIELFISLPFSILGCHSEDCDCEQCC
160 170 180 190 200
248 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:18:11 2016 done: Tue Nov 8 11:18:11 2016
Total Scan time: 2.250 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]