Result of FASTA (omim) for
pFN21AE6225
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6225, 222 aa
1>>>pF1KE6225 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1023+/-0.00031; mu= 15.1885+/- 0.019
mean_var=62.8036+/-12.622, 0's: 0 Z-trim(115.8): 38 B-trim: 48 in 1/53
Lambda= 0.161839
statistics sampled from 26436 (26474) to 26436 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.31), width: 16
Scan time: 4.810
The best scores are: opt bits E(85289)
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 1432 342.5 3.4e-94
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 1292 309.8 2.3e-84
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 1263 303.0 2.5e-82
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 1263 303.0 2.5e-82
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 1217 292.3 4.4e-79
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 1093 263.3 1.8e-70
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 1093 263.3 1.8e-70
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 1048 252.8 3.3e-67
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 835 203.1 3.1e-52
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 835 203.1 3.1e-52
XP_011512835 (OMIM: 605449) PREDICTED: glutathione ( 129) 825 200.6 9.9e-52
NP_001305988 (OMIM: 138359) glutathione S-transfer ( 129) 747 182.4 3e-46
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 628 154.7 9.4e-38
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 628 154.7 9.4e-38
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 295 77.0 2.6e-14
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 244 65.1 9.7e-11
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 211 57.4 2.2e-08
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 210 57.2 2.6e-08
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 203 55.5 8e-08
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 203 55.5 8e-08
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 195 53.7 2.9e-07
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 188 52.0 8.1e-07
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 181 50.4 2.6e-06
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 181 50.4 3.2e-06
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 173 48.5 1e-05
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 173 48.5 1e-05
NP_001299589 (OMIM: 603758) maleylacetoacetate iso ( 161) 169 47.5 1.5e-05
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 166 46.8 2.8e-05
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 158 45.0 0.0001
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 157 44.7 0.00012
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 143 41.5 0.0013
>>NP_000838 (OMIM: 605449) glutathione S-transferase A3 (222 aa)
initn: 1432 init1: 1432 opt: 1432 Z-score: 1812.1 bits: 342.5 E(85289): 3.4e-94
Smith-Waterman score: 1432; 99.5% identity (100.0% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
::::::::::::::::::::::::::::::::::::::::::
NP_000 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
190 200 210 220
>>NP_665683 (OMIM: 138359) glutathione S-transferase A1 (222 aa)
initn: 1292 init1: 1292 opt: 1292 Z-score: 1635.5 bits: 309.8 E(85289): 2.3e-84
Smith-Waterman score: 1292; 90.1% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
:: ::::::::.::::: :::::::::::::::: ::::: :::::: :::::::::::
NP_665 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.:::::::::::::::::::::::::::::::: ::.:::.:::::::.: :::::::
NP_665 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
.:::::: :.::::::::::.::::::::::::::::: :::::::::::::::::.:::
NP_665 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
::::::::::::::::::::::::::: : :.::::::::::
NP_665 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
190 200 210 220
>>NP_000837 (OMIM: 138360) glutathione S-transferase A2 (222 aa)
initn: 1263 init1: 1263 opt: 1263 Z-score: 1598.9 bits: 303.0 E(85289): 2.5e-82
Smith-Waterman score: 1263; 88.3% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
:: :::::: : ::::: ::::::::::::::::: ::::: :::::: :::::::::::
NP_000 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.:::::::::::::::::::::::::.:::::: ::.:::.:::::::. .:::.:::
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
.:::.::::.::::::::::.::::::::::::::::: :::::::::::::::::.:::
NP_000 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
::::::::::::::::::::::::::: : :.:::.::::::
NP_000 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>XP_011512834 (OMIM: 138360) PREDICTED: glutathione S-t (222 aa)
initn: 1263 init1: 1263 opt: 1263 Z-score: 1598.9 bits: 303.0 E(85289): 2.5e-82
Smith-Waterman score: 1263; 88.3% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
:: :::::: : ::::: ::::::::::::::::: ::::: :::::: :::::::::::
XP_011 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.:::::::::::::::::::::::::.:::::: ::.:::.:::::::. .:::.:::
XP_011 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
.:::.::::.::::::::::.::::::::::::::::: :::::::::::::::::.:::
XP_011 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
::::::::::::::::::::::::::: : :.:::.::::::
XP_011 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>NP_714543 (OMIM: 607605) glutathione S-transferase A5 (222 aa)
initn: 1217 init1: 1217 opt: 1217 Z-score: 1540.8 bits: 292.3 E(85289): 4.4e-79
Smith-Waterman score: 1217; 85.1% identity (93.2% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
:: :::::: :.:: :: :::::::::::.::::. ::::: ::::::::.:::::::::
NP_714 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.::::::::::::::::::::::.::::::::::::..::.:::::: .:.:::.:::
NP_714 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
::.::: :.::::::::::.:: :::::::::: ::: ::::.::::::::::::.:::
NP_714 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
:::::::::::::::::::::: :::: : :.::::::::::
NP_714 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
190 200 210 220
>>XP_016866283 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 1093 init1: 1093 opt: 1093 Z-score: 1386.0 bits: 263.3 E(85289): 1.8e-70
Smith-Waterman score: 1093; 99.4% identity (100.0% similar) in 172 aa overlap (51-222:1-172)
30 40 50 60 70 80
pF1KE6 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGIKLVQTRAILNYIASKYN
::::::::::::.:::::::::::::::::
XP_016 MFQQVPMVEIDGMKLVQTRAILNYIASKYN
10 20 30
90 100 110 120 130 140
pF1KE6 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE6 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
100 110 120 130 140 150
210 220
pF1KE6 GSPRKPPADAKALEEARKIFRF
::::::::::::::::::::::
XP_016 GSPRKPPADAKALEEARKIFRF
160 170
>>XP_006715135 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 1093 init1: 1093 opt: 1093 Z-score: 1386.0 bits: 263.3 E(85289): 1.8e-70
Smith-Waterman score: 1093; 99.4% identity (100.0% similar) in 172 aa overlap (51-222:1-172)
30 40 50 60 70 80
pF1KE6 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGIKLVQTRAILNYIASKYN
::::::::::::.:::::::::::::::::
XP_006 MFQQVPMVEIDGMKLVQTRAILNYIASKYN
10 20 30
90 100 110 120 130 140
pF1KE6 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE6 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
100 110 120 130 140 150
210 220
pF1KE6 GSPRKPPADAKALEEARKIFRF
::::::::::::::::::::::
XP_006 GSPRKPPADAKALEEARKIFRF
160 170
>>XP_005249091 (OMIM: 138359) PREDICTED: glutathione S-t (225 aa)
initn: 1066 init1: 1048 opt: 1048 Z-score: 1327.5 bits: 252.8 E(85289): 3.3e-67
Smith-Waterman score: 1051; 81.6% identity (88.8% similar) in 206 aa overlap (1-206:1-196)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
:: ::::::::.::::: :::::::::::::::: ::::: :::::: :::::::::::
XP_005 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.:::::::::::::::::::::::::::::::: ::.:::.:::::::.: :::::::
XP_005 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
.:::::: :.::::::::::.::::::::::::::::: :::::::::::::::::.:::
XP_005 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
:: .... . : ::: .:
XP_005 LK-----VTHFTA-----QRGSPTSPILGSCIWALRLTKFCPSLLQAFSAPRSPK
190 200 210 220
>>XP_005249092 (OMIM: 605450) PREDICTED: glutathione S-t (222 aa)
initn: 835 init1: 835 opt: 835 Z-score: 1058.8 bits: 203.1 E(85289): 3.1e-52
Smith-Waterman score: 835; 52.9% identity (83.7% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
::..::::: ::::::: .::.::::::::.:.:. . :.: ::.. . :.:::::::::
XP_005 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.::::::.::.:::.:.::.::..:::.:::::.:: :: :.... :. .:.... .
XP_005 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
.. . .:. ::::.:::.:..:::..::::.:: ::. :.. . .:: ...: ::.
XP_005 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
:. ...::.::.:.::.::: .::: : .. . .:::
XP_005 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
>>NP_001503 (OMIM: 605450) glutathione S-transferase A4 (222 aa)
initn: 835 init1: 835 opt: 835 Z-score: 1058.8 bits: 203.1 E(85289): 3.1e-52
Smith-Waterman score: 835; 52.9% identity (83.7% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE6 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
::..::::: ::::::: .::.::::::::.:.:. . :.: ::.. . :.:::::::::
NP_001 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGIKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
::.::::::.::.:::.:.::.::..:::.:::::.:: :: :.... :. .:.... .
NP_001 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
.. . .:. ::::.:::.:..:::..::::.:: ::. :.. . .:: ...: ::.
NP_001 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
130 140 150 160 170 180
190 200 210 220
pF1KE6 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
:. ...::.::.:.::.::: .::: : .. . .:::
NP_001 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
222 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:14:50 2016 done: Tue Nov 8 11:14:50 2016
Total Scan time: 4.810 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]