Result of FASTA (omim) for
pFN21AE6223
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6223, 240 aa
1>>>pF1KE6223 240 - 240 aa - 240 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2568+/-0.000354; mu= 20.1264+/- 0.022
mean_var=58.5400+/-11.871, 0's: 0 Z-trim(114.3): 29 B-trim: 782 in 1/56
Lambda= 0.167628
statistics sampled from 24037 (24063) to 24037 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.282), width: 16
Scan time: 5.090
The best scores are: opt bits E(85289)
NP_000844 (OMIM: 600436) glutathione S-transferase ( 240) 1595 393.7 1.5e-109
NP_000845 (OMIM: 600437) glutathione S-transferase ( 244) 824 207.2 2.1e-53
NP_001280736 (OMIM: 600436) glutathione S-transfer ( 226) 814 204.8 1e-52
NP_001280739 (OMIM: 600436) glutathione S-transfer ( 122) 808 203.1 1.8e-52
NP_001280738 (OMIM: 600436) glutathione S-transfer ( 122) 808 203.1 1.8e-52
NP_001280740 (OMIM: 600436) glutathione S-transfer ( 122) 808 203.1 1.8e-52
NP_001280737 (OMIM: 600436) glutathione S-transfer ( 122) 808 203.1 1.8e-52
NP_001280741 (OMIM: 600436) glutathione S-transfer ( 122) 808 203.1 1.8e-52
NP_001289599 (OMIM: 600437) glutathione S-transfer ( 230) 593 151.4 1.3e-36
NP_001280742 (OMIM: 600436) glutathione S-transfer ( 105) 438 113.5 1.4e-25
NP_001280743 (OMIM: 600436) glutathione S-transfer ( 72) 243 66.2 1.7e-11
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 141 42.0 0.00099
>>NP_000844 (OMIM: 600436) glutathione S-transferase the (240 aa)
initn: 1595 init1: 1595 opt: 1595 Z-score: 2087.7 bits: 393.7 E(85289): 1.5e-109
Smith-Waterman score: 1595; 99.6% identity (99.6% similar) in 240 aa overlap (1-240:1-240)
10 20 30 40 50 60
pF1KE6 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDACAQVNPLKKVPALKDG
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_000 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
190 200 210 220 230 240
>>NP_000845 (OMIM: 600437) glutathione S-transferase the (244 aa)
initn: 809 init1: 522 opt: 824 Z-score: 1079.9 bits: 207.2 E(85289): 2.1e-53
Smith-Waterman score: 824; 53.8% identity (74.4% similar) in 238 aa overlap (1-232:1-237)
10 20 30 40 50 60
pF1KE6 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDACAQVNPLKKVPALKDG
:::::.:::.::: :::::::::: ::.::: :::.:::: : :.: : :.:.::::
NP_000 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF
:: :::: :::.::. ::..::.:::.:::::::: :::.:. .: . :: .:.
NP_000 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA
:. .: : . . . . .: .:: :::::: .. ::.: ...::::.:. :::.::.
NP_000 PL-IGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVAL
130 140 150 160 170
190 200 210 220 230
pF1KE6 GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKA------KDFPPADPTIKQKLMPW
: ..:::::.::.:: :::: .: .: :::: .::. : .: .: : ..
NP_000 GYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLR
180 190 200 210 220 230
240
pF1KE6 VLAMIR
NP_000 IARIP
240
>>NP_001280736 (OMIM: 600436) glutathione S-transferase (226 aa)
initn: 1042 init1: 814 opt: 814 Z-score: 1067.3 bits: 204.8 E(85289): 1e-52
Smith-Waterman score: 996; 70.9% identity (78.3% similar) in 244 aa overlap (1-240:1-226)
10 20 30 40 50 60
pF1KE6 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDACAQVNPLKKVPALKDG
::::::::::::::::::::::::::::::::::::: :. . : :. .
NP_001 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIK-----DGVSLCRP--GWSAVAGS
10 20 30 40 50
70 80 90 100 110
pF1KE6 DFTLTES----VAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWH
..: : . : ::.: . . : . .. ..:. :. :
NP_001 QLTATSAARNLVLCLLFLLGRSALKRCLCPGEPPQEG----------ASLEGRGLH-LDG
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 KVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMH
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMH
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 PVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVL
170 180 190 200 210 220
240
pF1KE6 AMIR
::::
NP_001 AMIR
>>NP_001280739 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 808 init1: 808 opt: 808 Z-score: 1062.9 bits: 203.1 E(85289): 1.8e-52
Smith-Waterman score: 808; 100.0% identity (100.0% similar) in 122 aa overlap (119-240:1-122)
90 100 110 120 130 140
pF1KE6 LQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLE
::::::::::::::::::::::::::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLE
10 20 30
150 160 170 180 190 200
pF1KE6 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
40 50 60 70 80 90
210 220 230 240
pF1KE6 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
::::::::::::::::::::::::::::::::
NP_001 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280738 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 808 init1: 808 opt: 808 Z-score: 1062.9 bits: 203.1 E(85289): 1.8e-52
Smith-Waterman score: 808; 100.0% identity (100.0% similar) in 122 aa overlap (119-240:1-122)
90 100 110 120 130 140
pF1KE6 LQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLE
::::::::::::::::::::::::::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLE
10 20 30
150 160 170 180 190 200
pF1KE6 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
40 50 60 70 80 90
210 220 230 240
pF1KE6 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
::::::::::::::::::::::::::::::::
NP_001 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280740 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 808 init1: 808 opt: 808 Z-score: 1062.9 bits: 203.1 E(85289): 1.8e-52
Smith-Waterman score: 808; 100.0% identity (100.0% similar) in 122 aa overlap (119-240:1-122)
90 100 110 120 130 140
pF1KE6 LQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLE
::::::::::::::::::::::::::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLE
10 20 30
150 160 170 180 190 200
pF1KE6 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
40 50 60 70 80 90
210 220 230 240
pF1KE6 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
::::::::::::::::::::::::::::::::
NP_001 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280737 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 808 init1: 808 opt: 808 Z-score: 1062.9 bits: 203.1 E(85289): 1.8e-52
Smith-Waterman score: 808; 100.0% identity (100.0% similar) in 122 aa overlap (119-240:1-122)
90 100 110 120 130 140
pF1KE6 LQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLE
::::::::::::::::::::::::::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLE
10 20 30
150 160 170 180 190 200
pF1KE6 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
40 50 60 70 80 90
210 220 230 240
pF1KE6 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
::::::::::::::::::::::::::::::::
NP_001 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001280741 (OMIM: 600436) glutathione S-transferase (122 aa)
initn: 808 init1: 808 opt: 808 Z-score: 1062.9 bits: 203.1 E(85289): 1.8e-52
Smith-Waterman score: 808; 100.0% identity (100.0% similar) in 122 aa overlap (119-240:1-122)
90 100 110 120 130 140
pF1KE6 LQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLE
::::::::::::::::::::::::::::::
NP_001 MFPVFLGEPVSPQTLAATLAELDVTLQLLE
10 20 30
150 160 170 180 190 200
pF1KE6 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQ
40 50 60 70 80 90
210 220 230 240
pF1KE6 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
::::::::::::::::::::::::::::::::
NP_001 EAHEVILKAKDFPPADPTIKQKLMPWVLAMIR
100 110 120
>>NP_001289599 (OMIM: 600437) glutathione S-transferase (230 aa)
initn: 733 init1: 522 opt: 593 Z-score: 778.4 bits: 151.4 E(85289): 1.3e-36
Smith-Waterman score: 732; 50.4% identity (69.3% similar) in 238 aa overlap (1-232:1-223)
10 20 30 40 50 60
pF1KE6 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDACAQVNPLKKVPALKDG
:::::.:::.::: :::::::::: ::.::: :::.:::: : :.: : :.:.::::
NP_001 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF
:: :::: :::.::. ::..::.:::.:::::::: :::.:. .: . :: .:.
NP_001 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA
:. .: : . . . . .: .:: :::::: .. ::.: ..::.
NP_001 PL-IGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAG--------------QQPVAL
130 140 150 160
190 200 210 220 230
pF1KE6 GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKA------KDFPPADPTIKQKLMPW
: ..:::::.::.:: :::: .: .: :::: .::. : .: .: : ..
NP_001 GYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLR
170 180 190 200 210 220
240
pF1KE6 VLAMIR
NP_001 IARIP
230
>>NP_001280742 (OMIM: 600436) glutathione S-transferase (105 aa)
initn: 463 init1: 428 opt: 438 Z-score: 580.1 bits: 113.5 E(85289): 1.4e-25
Smith-Waterman score: 438; 69.4% identity (78.7% similar) in 108 aa overlap (1-108:1-100)
10 20 30 40 50 60
pF1KE6 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDACAQVNPLKKVPALKDG
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF
::::::: .: ... :. : :. .: . : .:. ::
NP_001 DFTLTESPWVLA--AKSSKADPSW-PHGGSAWRQ-----QWGRTSSRRPMRSF
70 80 90 100
130 140 150 160 170 180
pF1KE6 PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA
240 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:13:46 2016 done: Tue Nov 8 11:13:47 2016
Total Scan time: 5.090 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]