FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6219, 182 aa
  1>>>pF1KE6219 182 - 182 aa - 182 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9802+/-0.000342; mu= 6.0185+/- 0.021
 mean_var=129.0210+/-26.266, 0's: 0 Z-trim(119.1): 22  B-trim: 1065 in 1/52
 Lambda= 0.112913
 statistics sampled from 32772 (32808) to 32772 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.385), width:  16
 Scan time:  5.200

The best scores are:                                      opt bits E(85289)
NP_003273 (OMIM: 191043,601680) troponin I, fast s ( 182) 1191 204.3 8.7e-53
NP_001139301 (OMIM: 191043,601680) troponin I, fas ( 182) 1191 204.3 8.7e-53
NP_001139313 (OMIM: 191043,601680) troponin I, fas ( 182) 1161 199.5 2.6e-51
NP_003272 (OMIM: 191042) troponin I, slow skeletal ( 187)  694 123.4 2.1e-28
NP_000354 (OMIM: 115210,191044,611880,613286,61369 ( 210)  677 120.7 1.6e-27


>>NP_003273 (OMIM: 191043,601680) troponin I, fast skele  (182 aa)
 initn: 1191 init1: 1191 opt: 1191  Z-score: 1068.7  bits: 204.3 E(85289): 8.7e-53
Smith-Waterman score: 1191; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)

               10        20        30        40        50        60
pF1KE6 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
              130       140       150       160       170       180

         
pF1KE6 ES
       ::
NP_003 ES
         

>>NP_001139301 (OMIM: 191043,601680) troponin I, fast sk  (182 aa)
 initn: 1191 init1: 1191 opt: 1191  Z-score: 1068.7  bits: 204.3 E(85289): 8.7e-53
Smith-Waterman score: 1191; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)

               10        20        30        40        50        60
pF1KE6 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
              130       140       150       160       170       180

         
pF1KE6 ES
       ::
NP_001 ES
         

>>NP_001139313 (OMIM: 191043,601680) troponin I, fast sk  (182 aa)
 initn: 1161 init1: 1161 opt: 1161  Z-score: 1042.3  bits: 199.5 E(85289): 2.6e-51
Smith-Waterman score: 1161; 97.8% identity (99.5% similar) in 182 aa overlap (1-182:1-182)

               10        20        30        40        50        60
pF1KE6 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
       :.. .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQCKKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
              130       140       150       160       170       180

         
pF1KE6 ES
       ::
NP_001 ES
         

>>NP_003272 (OMIM: 191042) troponin I, slow skeletal mus  (187 aa)
 initn: 580 init1: 458 opt: 694  Z-score: 631.0  bits: 123.4 E(85289): 2.1e-28
Smith-Waterman score: 694; 58.6% identity (83.4% similar) in 181 aa overlap (1-180:1-180)

               10        20        30        40        50          
pF1KE6 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS
       : . :.. .  ..:.  :::.::  :    :.:. .:::::  ::::. : :.  : :.:
NP_003 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE6 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA
        .:.::..::::.....::.::.:..  ....:..:.. :..:::::::::::::::.::
NP_003 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSA
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE6 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE
       ::::.::::::::: ::::::::.:::::::::: . .:::::::.:  ::::::::::.
NP_003 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD
              130       140       150        160       170         

     180       
pF1KE6 SES     
       .       
NP_003 AAKSPTSQ
     180       

>>NP_000354 (OMIM: 115210,191044,611880,613286,613690) t  (210 aa)
 initn: 532 init1: 430 opt: 677  Z-score: 615.3  bits: 120.7 E(85289): 1.6e-27
Smith-Waterman score: 677; 57.1% identity (83.6% similar) in 177 aa overlap (5-180:36-210)

                                         10        20        30    
pF1KE6                           MGDEEKRNRAITARRQHLKSVMLQIAATELEKEE
                                     .:...  ..:. .::...::::  :::.: 
NP_000 SDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREA
          10        20        30        40        50        60     

           40        50         60        70        80        90   
pF1KE6 SRREAEKQNYLAEHCPPLHIPG-SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKEL
        .:..::   :. .: ::.. : ...:.:.::.::::..: ..::.::.:..: :.  :.
NP_000 EERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEI
          70        80        90       100       110       120     

           100       110       120       130       140       150   
pF1KE6 EDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKER
        :..::.:::::::::: :::::.:::::..::::.. :  .::::.:::::::::::: 
NP_000 ADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKEN
         130       140       150       160       170       180     

           160       170       180  
pF1KE6 DLRDVGDWRKNIEEKSGMEGRKKMFESES
         :.::::::::.  :::::::: :::  
NP_000 --REVGDWRKNIDALSGMEGRKKKFES  
           190       200       210  




182 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 11:11:44 2016 done: Tue Nov  8 11:11:45 2016
 Total Scan time:  5.200 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]