Result of FASTA (omim) for
pFN21AE6215
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6215, 265 aa
1>>>pF1KE6215 265 - 265 aa - 265 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2985+/-0.000343; mu= 15.0832+/- 0.021
mean_var=66.6564+/-13.011, 0's: 0 Z-trim(114.6): 65 B-trim: 35 in 1/54
Lambda= 0.157092
statistics sampled from 24485 (24550) to 24485 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.288), width: 16
Scan time: 6.400
The best scores are: opt bits E(85289)
NP_000366 (OMIM: 263700,606938) uroporphyrinogen-I ( 265) 1743 403.6 1.9e-112
NP_001310965 (OMIM: 263700,606938) uroporphyrinoge ( 292) 1454 338.2 1.1e-92
XP_016872099 (OMIM: 263700,606938) PREDICTED: urop ( 301) 1444 335.9 5.2e-92
XP_016872100 (OMIM: 263700,606938) PREDICTED: urop ( 301) 1444 335.9 5.2e-92
XP_016872101 (OMIM: 263700,606938) PREDICTED: urop ( 262) 1438 334.5 1.2e-91
XP_005270197 (OMIM: 263700,606938) PREDICTED: urop ( 223) 1437 334.2 1.2e-91
XP_011538429 (OMIM: 263700,606938) PREDICTED: urop ( 234) 1437 334.3 1.3e-91
NP_001310966 (OMIM: 263700,606938) uroporphyrinoge ( 265) 1137 266.3 4.1e-71
NP_001310968 (OMIM: 263700,606938) uroporphyrinoge ( 139) 862 203.8 1.4e-52
NP_001310967 (OMIM: 263700,606938) uroporphyrinoge ( 238) 864 204.4 1.6e-52
>>NP_000366 (OMIM: 263700,606938) uroporphyrinogen-III s (265 aa)
initn: 1743 init1: 1743 opt: 1743 Z-score: 2139.9 bits: 403.6 E(85289): 1.9e-112
Smith-Waterman score: 1743; 100.0% identity (100.0% similar) in 265 aa overlap (1-265:1-265)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
190 200 210 220 230 240
250 260
pF1KE6 CTAESPTPQALATGIRKALQPHGCC
:::::::::::::::::::::::::
NP_000 CTAESPTPQALATGIRKALQPHGCC
250 260
>>NP_001310965 (OMIM: 263700,606938) uroporphyrinogen-II (292 aa)
initn: 1482 init1: 1451 opt: 1454 Z-score: 1785.3 bits: 338.2 E(85289): 1.1e-92
Smith-Waterman score: 1679; 90.8% identity (90.8% similar) in 292 aa overlap (1-265:1-292)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIK--------------------
::::::::::::::::::::::::::::::::::::::::
NP_001 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKTQGPQHPKKNCLQLEPLRKD
190 200 210 220 230 240
230 240 250 260
pF1KE6 -------FAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTDTAVMFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC
250 260 270 280 290
>>XP_016872099 (OMIM: 263700,606938) PREDICTED: uroporph (301 aa)
initn: 1441 init1: 1441 opt: 1444 Z-score: 1772.9 bits: 335.9 E(85289): 5.2e-92
Smith-Waterman score: 1444; 92.6% identity (93.9% similar) in 244 aa overlap (1-242:1-242)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPV-
:::::::::::::::::::::::::::::::::::::::: :: . : :.
XP_016 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKTQ--GPQHPKKNCLQLEPLR
190 200 210 220 230
240 250 260
pF1KE6 -SCTAESPTPQALATGIRKALQPHGCC
.::
XP_016 KDCTDTAVMVSTSLGPSSPCPSPEPGDSRSGWQTDESVDAEVFCTLRSWARIGQCCHFYK
240 250 260 270 280 290
>>XP_016872100 (OMIM: 263700,606938) PREDICTED: uroporph (301 aa)
initn: 1441 init1: 1441 opt: 1444 Z-score: 1772.9 bits: 335.9 E(85289): 5.2e-92
Smith-Waterman score: 1444; 92.6% identity (93.9% similar) in 244 aa overlap (1-242:1-242)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPV-
:::::::::::::::::::::::::::::::::::::::: :: . : :.
XP_016 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKTQ--GPQHPKKNCLQLEPLR
190 200 210 220 230
240 250 260
pF1KE6 -SCTAESPTPQALATGIRKALQPHGCC
.::
XP_016 KDCTDTAVMVSTSLGPSSPCPSPEPGDSRSGWQTDESVDAEVFCTLRSWARIGQCCHFYK
240 250 260 270 280 290
>>XP_016872101 (OMIM: 263700,606938) PREDICTED: uroporph (262 aa)
initn: 1438 init1: 1438 opt: 1438 Z-score: 1766.4 bits: 334.5 E(85289): 1.2e-91
Smith-Waterman score: 1438; 99.5% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
::::::::::::::::::::::::::::::::::::::::.
XP_016 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKLLDGGELLKKFMQGRNKGSH
190 200 210 220 230 240
250 260
pF1KE6 CTAESPTPQALATGIRKALQPHGCC
XP_016 RNLRAKVKCNWPPRPRGASSEN
250 260
>>XP_005270197 (OMIM: 263700,606938) PREDICTED: uroporph (223 aa)
initn: 1437 init1: 1437 opt: 1437 Z-score: 1766.2 bits: 334.2 E(85289): 1.2e-91
Smith-Waterman score: 1437; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
::::::::::::::::::::::::::::::::::::::::
XP_005 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKKHP
190 200 210 220
250 260
pF1KE6 CTAESPTPQALATGIRKALQPHGCC
>>XP_011538429 (OMIM: 263700,606938) PREDICTED: uroporph (234 aa)
initn: 1437 init1: 1437 opt: 1437 Z-score: 1765.9 bits: 334.3 E(85289): 1.3e-91
Smith-Waterman score: 1437; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
::::::::::::::::::::::::::::::::::::::::
XP_011 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKIEELELQWASWALR
190 200 210 220 230
250 260
pF1KE6 CTAESPTPQALATGIRKALQPHGCC
>>NP_001310966 (OMIM: 263700,606938) uroporphyrinogen-II (265 aa)
initn: 1061 init1: 1061 opt: 1137 Z-score: 1397.7 bits: 266.3 E(85289): 4.1e-71
Smith-Waterman score: 1435; 81.5% identity (81.5% similar) in 292 aa overlap (1-265:1-265)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
:::::::::::: :::::::::::::::::::::
NP_001 NAEKLAEYICSR---------------------------IAMESITVYQTVAHPGIQGNL
130 140 150
190 200 210 220
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIK--------------------
::::::::::::::::::::::::::::::::::::::::
NP_001 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKTQGPQHPKKNCLQLEPLRKD
160 170 180 190 200 210
230 240 250 260
pF1KE6 -------FAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTDTAVMFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC
220 230 240 250 260
>>NP_001310968 (OMIM: 263700,606938) uroporphyrinogen-II (139 aa)
initn: 876 init1: 862 opt: 862 Z-score: 1065.0 bits: 203.8 E(85289): 1.4e-52
Smith-Waterman score: 862; 99.2% identity (99.2% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
::::::::::: :
NP_001 NAEKLAEYICSSEEVKGIF
130
>>NP_001310967 (OMIM: 263700,606938) uroporphyrinogen-II (238 aa)
initn: 1549 init1: 864 opt: 864 Z-score: 1064.0 bits: 204.4 E(85289): 1.6e-52
Smith-Waterman score: 1499; 89.8% identity (89.8% similar) in 265 aa overlap (1-265:1-238)
10 20 30 40 50 60
pF1KE6 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
:::::::::::: :::::::::::::::::::::
NP_001 NAEKLAEYICSR---------------------------IAMESITVYQTVAHPGIQGNL
130 140 150
190 200 210 220 230 240
pF1KE6 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
160 170 180 190 200 210
250 260
pF1KE6 CTAESPTPQALATGIRKALQPHGCC
:::::::::::::::::::::::::
NP_001 CTAESPTPQALATGIRKALQPHGCC
220 230
265 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:09:30 2016 done: Tue Nov 8 11:09:30 2016
Total Scan time: 6.400 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]