Result of FASTA (omim) for
pFN21AE6206
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6206, 198 aa
1>>>pF1KE6206 198 - 198 aa - 198 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5931+/-0.000376; mu= 16.8355+/- 0.023
mean_var=58.1507+/-11.913, 0's: 0 Z-trim(113.2): 35 B-trim: 568 in 1/50
Lambda= 0.168189
statistics sampled from 22471 (22506) to 22471 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.264), width: 16
Scan time: 5.210
The best scores are: opt bits E(85289)
NP_065712 (OMIM: 605257,605258) single-stranded DN ( 198) 1397 347.0 1.2e-95
NP_001317272 (OMIM: 605257,605258) single-stranded ( 188) 1020 255.5 3.8e-68
XP_011519075 (OMIM: 605257,605258) PREDICTED: sing ( 145) 1007 252.3 2.8e-67
NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme ( 373) 489 126.9 4e-29
XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 442) 489 127.0 4.5e-29
NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme ( 190) 485 125.7 4.6e-29
NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme ( 386) 449 117.2 3.4e-26
XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 455) 449 117.3 3.9e-26
XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 317) 402 105.7 7.9e-23
NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme ( 384) 402 105.8 9.2e-23
XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 457) 402 105.9 1.1e-22
XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 524) 402 105.9 1.2e-22
XP_005261394 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 202) 384 101.2 1.2e-21
NP_001257335 (OMIM: 607109) DNA dC->dU-editing enz ( 181) 378 99.7 2.9e-21
NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme ( 199) 378 99.8 3.1e-21
XP_011528294 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 200) 378 99.8 3.2e-21
NP_001159475 (OMIM: 610976) DNA dC->dU-editing enz ( 200) 378 99.8 3.2e-21
XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 227) 378 99.8 3.5e-21
NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme ( 382) 379 100.2 4.4e-21
NP_001159474 (OMIM: 610976) DNA dC->dU-editing enz ( 182) 369 97.5 1.3e-20
NP_861438 (OMIM: 610976) DNA dC->dU-editing enzyme ( 183) 369 97.5 1.3e-20
XP_011528292 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 369 97.6 1.4e-20
XP_011528293 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 369 97.6 1.4e-20
NP_006780 (OMIM: 604797) C->U-editing enzyme APOBE ( 224) 358 94.9 9.9e-20
NP_001257340 (OMIM: 607110) DNA dC->dU-editing enz ( 357) 355 94.4 2.4e-19
NP_001159476 (OMIM: 610976) DNA dC->dU-editing enz ( 154) 299 80.5 1.5e-15
NP_001635 (OMIM: 600130) C->U-editing enzyme APOBE ( 236) 288 78.0 1.3e-14
NP_001291495 (OMIM: 600130) C->U-editing enzyme AP ( 236) 288 78.0 1.3e-14
NP_005880 (OMIM: 600130) C->U-editing enzyme APOBE ( 191) 287 77.7 1.3e-14
>>NP_065712 (OMIM: 605257,605258) single-stranded DNA cy (198 aa)
initn: 1397 init1: 1397 opt: 1397 Z-score: 1838.4 bits: 347.0 E(85289): 1.2e-95
Smith-Waterman score: 1397; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198)
10 20 30 40 50 60
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL
130 140 150 160 170 180
190
pF1KE6 LPLYEVDDLRDAFRTLGL
::::::::::::::::::
NP_065 LPLYEVDDLRDAFRTLGL
190
>>NP_001317272 (OMIM: 605257,605258) single-stranded DNA (188 aa)
initn: 1009 init1: 1009 opt: 1020 Z-score: 1344.4 bits: 255.5 E(85289): 3.8e-68
Smith-Waterman score: 1282; 94.9% identity (94.9% similar) in 198 aa overlap (1-198:1-188)
10 20 30 40 50 60
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL
:::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 AEPEGLRRLHRAGVQIAIMTFK----------ENHERTFKAWEGLHENSVRLSRQLRRIL
130 140 150 160 170
190
pF1KE6 LPLYEVDDLRDAFRTLGL
::::::::::::::::::
NP_001 LPLYEVDDLRDAFRTLGL
180
>>XP_011519075 (OMIM: 605257,605258) PREDICTED: single-s (145 aa)
initn: 1007 init1: 1007 opt: 1007 Z-score: 1328.9 bits: 252.3 E(85289): 2.8e-67
Smith-Waterman score: 1007; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL
::::::::::::::::::::::
XP_011 AEPEGLRRLHRAGVQIAIMTFKAPV
130 140
>>NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme APO (373 aa)
initn: 606 init1: 232 opt: 489 Z-score: 643.9 bits: 126.9 E(85289): 4e-29
Smith-Waterman score: 489; 43.1% identity (69.0% similar) in 174 aa overlap (11-180:200-372)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSAT
: ..:::.: : :: :..::.... .
NP_660 WYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHS
170 180 190 200 210 220
50 60 70 80 90
pF1KE6 SFSLDFGYLRNK----NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAD
: : .::. . ::.: :: .. : :.:. :.:::.:::::: .:: .::.
NP_660 PVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAE
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE6 FLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
:: . :..: :::::::. : . :::: : . :... :: .::. :::..:: : .
NP_660 FLARHSNVNLTIFTARLYYFWDTDYQ-EGLRSLSQEGASVEIMGYKDFKYCWENFVYNDD
290 300 310 320 330 340
160 170 180 190
pF1KE6 RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
. :: :.::. : . :. .:..::
NP_660 EPFKPWKGLKYNFLFLDSKLQEILE
350 360 370
>--
initn: 347 init1: 194 opt: 378 Z-score: 498.3 bits: 100.0 E(85289): 5.1e-21
Smith-Waterman score: 378; 36.7% identity (64.4% similar) in 180 aa overlap (6-180:12-188)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRET-YLCYVVKRRDSATSFSLD---F-GYL
: : : :.: : : .::.: .::: :: . . :: : : .
NP_660 MKPHFRNTVERMYRDTFSYNFYN-RPILSRRNTVWLCYEVKTKGPSRP-RLDAKIFRGQV
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 RNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIF
.. :.:. :: .. .: .:...:::.::.:: ::. ..:.:: .::..: :
NP_660 YSQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTIS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 TARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENS
.::::. .: . ..: :: .::... :: ... :::..:: .. . : : . .:
NP_660 AARLYYYWERDYR-RALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNY
120 130 140 150 160 170
170 180 190
pF1KE6 VRLSRQLRRILLPLYEVDDLRDAFRTLGL
. : : :..::
NP_660 AFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGV
180 190 200 210 220 230
>>XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU-edit (442 aa)
initn: 606 init1: 232 opt: 489 Z-score: 642.9 bits: 127.0 E(85289): 4.5e-29
Smith-Waterman score: 489; 43.1% identity (69.0% similar) in 174 aa overlap (11-180:269-441)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSAT
: ..:::.: : :: :..::.... .
XP_011 WYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHS
240 250 260 270 280 290
50 60 70 80 90
pF1KE6 SFSLDFGYLRNK----NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAD
: : .::. . ::.: :: .. : :.:. :.:::.:::::: .:: .::.
XP_011 PVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAE
300 310 320 330 340 350
100 110 120 130 140 150
pF1KE6 FLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
:: . :..: :::::::. : . :::: : . :... :: .::. :::..:: : .
XP_011 FLARHSNVNLTIFTARLYYFWDTDYQ-EGLRSLSQEGASVEIMGYKDFKYCWENFVYNDD
360 370 380 390 400 410
160 170 180 190
pF1KE6 RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
. :: :.::. : . :. .:..::
XP_011 EPFKPWKGLKYNFLFLDSKLQEILE
420 430 440
>--
initn: 338 init1: 194 opt: 287 Z-score: 378.0 bits: 77.9 E(85289): 2.6e-14
Smith-Waterman score: 287; 38.1% identity (64.7% similar) in 139 aa overlap (6-139:12-147)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRET-YLCYVVKRRDSATSFSLD---F-GYL
: : : :.: : : .::.: .::: :: . . :: : : .
XP_011 MKPHFRNTVERMYRDTFSYNFYN-RPILSRRNTVWLCYEVKTKGPSRP-RLDAKIFRGQV
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 RNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIF
.. :.:. :: .. .: .:...:::.::.:: ::. ..:.:: .::..: :
XP_011 YSQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTIS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 TARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENS
.::::. .: . ..: :: .::... ::
XP_011 AARLYYYWERDYR-RALCRLSQAGARVKIMDDEGERWRGQGSVSGRNSMKDGWICNAMAG
120 130 140 150 160 170
>>NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme APO (190 aa)
initn: 495 init1: 238 opt: 485 Z-score: 642.7 bits: 125.7 E(85289): 4.6e-29
Smith-Waterman score: 485; 44.9% identity (69.3% similar) in 176 aa overlap (11-180:17-189)
10 20 30 40 50
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVK--RRDSATSFSLDFGYLRNK
: .::::. :. : ::.::..:. .: :..:.. : .::.
NP_055 MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKRRSVVSWKT--GVFRNQ
10 20 30 40 50
60 70 80 90 100
pF1KE6 ----NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRI
. ::.: :: .. : :.:. :.:::.:::::: ::: .::.:: . :..: :
NP_055 VDSETHCHAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 FTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHEN
::::::. . :::: : . :: . :: ..:. :::..:: : .. :: :.::. :
NP_055 FTARLYYFQ-YPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEPFKPWKGLKTN
120 130 140 150 160 170
170 180 190
pF1KE6 SVRLSRQLRRILLPLYEVDDLRDAFRTLGL
:.:.::. :
NP_055 FRLLKRRLRESLQ
180 190
>>NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme APO (386 aa)
initn: 494 init1: 221 opt: 449 Z-score: 591.2 bits: 117.2 E(85289): 3.4e-26
Smith-Waterman score: 449; 40.8% identity (66.7% similar) in 174 aa overlap (11-180:213-385)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSAT
: ..:::. : :: :..::.... .
NP_689 WYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHS
190 200 210 220 230 240
50 60 70 80 90
pF1KE6 SFSLDFGYLRNK----NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAD
. : .::. . ::.: :: .. : :.:. :.:::.:::::: .:: .::.
NP_689 AVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAE
250 260 270 280 290 300
100 110 120 130 140 150
pF1KE6 FLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
:: . :..: :::::: . : . ::: : . :... :: .::. ::..:: . .
NP_689 FLARHSNVNLTIFTARLCYFWDTDYQ-EGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDD
310 320 330 340 350 360
160 170 180 190
pF1KE6 RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
. :: :.::. : :.:.::.::
NP_689 EPFKPWKGLQTNFRLLKRRLREILQ
370 380
>--
initn: 407 init1: 198 opt: 381 Z-score: 502.1 bits: 100.7 E(85289): 3.2e-21
Smith-Waterman score: 381; 35.2% identity (59.1% similar) in 193 aa overlap (6-180:12-201)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFG-------
: : : .:.: :: :.::: :: . . ... : :
NP_689 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL
10 20 30 40 50 60
50 60 70 80 90
pF1KE6 -----------YLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAD
:.: .: :.:. :: .. : .: ...:::.::.:: :. .:.
NP_689 PKRQSNHRQEVYFRFEN--HAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTK
70 80 90 100 110
100 110 120 130 140 150
pF1KE6 FLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
:: .::..: : .::::. .:: . : :::.::... :: ..:. :::..:: :.
NP_689 FLAEHPNVTLTISAARLYYYRDRDWR-WVLLRLHKAGARVKIMDYEDFAYCWENFVCNEG
120 130 140 150 160 170
160 170 180 190
pF1KE6 RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
. : : . .: . : : :..::
NP_689 QPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEV
180 190 200 210 220 230
>>XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU-edit (455 aa)
initn: 494 init1: 221 opt: 449 Z-score: 590.2 bits: 117.3 E(85289): 3.9e-26
Smith-Waterman score: 449; 40.8% identity (66.7% similar) in 174 aa overlap (11-180:282-454)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSAT
: ..:::. : :: :..::.... .
XP_016 WYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHS
260 270 280 290 300 310
50 60 70 80 90
pF1KE6 SFSLDFGYLRNK----NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAD
. : .::. . ::.: :: .. : :.:. :.:::.:::::: .:: .::.
XP_016 AVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAE
320 330 340 350 360 370
100 110 120 130 140 150
pF1KE6 FLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
:: . :..: :::::: . : . ::: : . :... :: .::. ::..:: . .
XP_016 FLARHSNVNLTIFTARLCYFWDTDYQ-EGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDD
380 390 400 410 420 430
160 170 180 190
pF1KE6 RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
. :: :.::. : :.:.::.::
XP_016 EPFKPWKGLQTNFRLLKRRLREILQ
440 450
>--
initn: 348 init1: 198 opt: 272 Z-score: 358.1 bits: 74.3 E(85289): 3.3e-13
Smith-Waterman score: 272; 34.2% identity (57.4% similar) in 155 aa overlap (6-142:12-163)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFG-------
: : : .:.: :: :.::: :: . . ... : :
XP_016 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL
10 20 30 40 50 60
50 60 70 80 90
pF1KE6 -----------YLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVAD
:.: .: :.:. :: .. : .: ...:::.::.:: :. .:.
XP_016 PKRQSNHRQEVYFRFEN--HAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTK
70 80 90 100 110
100 110 120 130 140 150
pF1KE6 FLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
:: .::..: : .::::. .:: . : :::.::... :: ..
XP_016 FLAEHPNVTLTISAARLYYYRDRDWRWV-LLRLHKAGARVKIMDYEGERCRGQGSMTGRN
120 130 140 150 160 170
160 170 180 190
pF1KE6 RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
XP_016 SLRDGWICNAMAGGVPGQPAGVGLALIATDSQETRPGRAGPGSGESLSASHLFISDFAYC
180 190 200 210 220 230
>>XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (317 aa)
initn: 384 init1: 207 opt: 402 Z-score: 530.8 bits: 105.7 E(85289): 7.9e-23
Smith-Waterman score: 491; 44.3% identity (68.6% similar) in 185 aa overlap (6-180:130-312)
10 20 30
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKR
:. : ..:.: :..::.:::::: :.:
XP_006 SQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVER
100 110 120 130 140 150
40 50 60 70 80
pF1KE6 --RDSATSFSLDFGYLRNK--------NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWS
:. . .. :.: :. .: :.:: :: : : :: . :::: :::::
XP_006 MHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWS
160 170 180 190 200 210
90 100 110 120 130 140
pF1KE6 PCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYF
::..::...: :. : ..:: :::::.: .:. :::: : .::..:.:::....
XP_006 PCFSCAQEMAKFISKNKHVSLCIFTARIY--DDQGRCQEGLRTLAEAGAKISIMTYSEFK
220 230 240 250 260 270
150 160 170 180 190
pF1KE6 YCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
.::.:::... :. :.:: :.: :: .:: ::
XP_006 HCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
280 290 300 310
>--
initn: 274 init1: 166 opt: 278 Z-score: 368.2 bits: 75.6 E(85289): 9.1e-14
Smith-Waterman score: 278; 36.8% identity (66.4% similar) in 125 aa overlap (61-180:3-126)
40 50 60 70 80
pF1KE6 YVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDW-DLDPGRCYRVTWFTSWSPCYD
:....: : : . :.:::. :::::
XP_006 MRFFHWFSKWRKLHRDQEYEVTWYISWSPCTK
10 20 30
90 100 110 120 130 140
pF1KE6 CARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRL--HRAG--VQIAIMTFKDYF
:.: .: :: .:...: ::.::::. : . :.:: : .: : . . ::.. ..
XP_006 CTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQ-EALRSLCQKRDGPRATMKIMNYDEFQ
40 50 60 70 80 90
150 160 170 180 190
pF1KE6 YCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
.::. :: .... :. :..: . . : .: .::
XP_006 HCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHET
100 110 120 130 140 150
XP_006 YLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYR
160 170 180 190 200 210
>>NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme APO (384 aa)
initn: 459 init1: 207 opt: 402 Z-score: 529.6 bits: 105.8 E(85289): 9.2e-23
Smith-Waterman score: 491; 44.3% identity (68.6% similar) in 185 aa overlap (6-180:197-379)
10 20 30
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKR
:. : ..:.: :..::.:::::: :.:
NP_068 SQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVER
170 180 190 200 210 220
40 50 60 70 80
pF1KE6 --RDSATSFSLDFGYLRNK--------NGCHVELLFLRYISDWDLDPGRCYRVTWFTSWS
:. . .. :.: :. .: :.:: :: : : :: . :::: :::::
NP_068 MHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWS
230 240 250 260 270 280
90 100 110 120 130 140
pF1KE6 PCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYF
::..::...: :. : ..:: :::::.: .:. :::: : .::..:.:::....
NP_068 PCFSCAQEMAKFISKNKHVSLCIFTARIY--DDQGRCQEGLRTLAEAGAKISIMTYSEFK
290 300 310 320 330 340
150 160 170 180 190
pF1KE6 YCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
.::.:::... :. :.:: :.: :: .:: ::
NP_068 HCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
350 360 370 380
>--
initn: 296 init1: 166 opt: 335 Z-score: 441.8 bits: 89.5 E(85289): 7.2e-18
Smith-Waterman score: 335; 36.2% identity (61.6% similar) in 185 aa overlap (6-180:12-193)
10 20 30 40
pF1KE6 MDSLLMNRRKFLYQFKNVRWAKGRRET-YLCYVVKRRDSATSFSLD---F-GYL
: : : :.: : : .::.: .::: :: . . :: : : .
NP_068 MKPHFRNTVERMYRDTFSYNFYN-RPILSRRNTVWLCYEVKTKGPSRP-PLDAKIFRGQV
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 RNKNGCHVELLFLRYISDW-DLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRI
.. : :. :....: : : . :.:::. ::::: :.: .: :: .:...: :
NP_068 YSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 FTARLYFCEDRKAEPEGLRRL--HRAG--VQIAIMTFKDYFYCWNTFVENHERTFKAWEG
:.::::. : . :.:: : .: : . . ::.. .. .::. :: .... :. :..
NP_068 FVARLYYFWDPDYQ-EALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNN
120 130 140 150 160 170
170 180 190
pF1KE6 LHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
: . . : .: .::
NP_068 LPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQ
180 190 200 210 220 230
198 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:04:47 2016 done: Tue Nov 8 11:04:48 2016
Total Scan time: 5.210 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]