Result of FASTA (omim) for
pFN21AE6167
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6167, 134 aa
1>>>pF1KE6167 134 - 134 aa - 134 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8240+/-0.000335; mu= 13.1299+/- 0.021
mean_var=55.0074+/-11.453, 0's: 0 Z-trim(113.4): 32 B-trim: 1308 in 1/50
Lambda= 0.172927
statistics sampled from 22663 (22695) to 22663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.266), width: 16
Scan time: 2.850
The best scores are: opt bits E(85289)
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 927 239.0 1.8e-63
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 562 148.0 6.3e-36
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 556 146.4 1.3e-35
NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 485 128.7 2.8e-30
XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 416 111.5 4e-25
NP_001316383 (OMIM: 611866) retinol-binding protei ( 86) 335 91.2 3.5e-19
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 319 87.3 8e-18
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 314 86.0 2e-17
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 314 86.0 2e-17
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 314 86.0 2e-17
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 312 85.6 3e-17
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 309 84.8 5.2e-17
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 307 84.3 6.4e-17
NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 307 84.3 6.4e-17
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 306 84.1 7.8e-17
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 303 83.3 1.5e-16
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 301 82.8 1.8e-16
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 297 81.8 3.5e-16
NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 250 70.1 1.3e-12
NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 245 68.8 2.2e-12
NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 241 67.8 5.6e-12
NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 205 58.9 3e-09
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 160 47.6 7e-06
NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 121 37.9 0.0057
>>NP_443192 (OMIM: 608604) retinoid-binding protein 7 [H (134 aa)
initn: 927 init1: 927 opt: 927 Z-score: 1260.6 bits: 239.0 E(85289): 1.8e-63
Smith-Waterman score: 927; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134)
10 20 30 40 50 60
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
70 80 90 100 110 120
130
pF1KE6 FCEGQVCKQTFQRA
::::::::::::::
NP_443 FCEGQVCKQTFQRA
130
>>NP_002890 (OMIM: 180260) retinol-binding protein 1 iso (197 aa)
initn: 589 init1: 562 opt: 562 Z-score: 766.0 bits: 148.0 E(85289): 6.3e-36
Smith-Waterman score: 562; 57.1% identity (82.7% similar) in 133 aa overlap (1-133:63-195)
10 20 30
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFAT
::.:..: : .: ..::: :. :: .. :
NP_002 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE6 RKIAKLLKPQKVIEQNGDSFTIHTNSSLRNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWD
::::.::::.: : :.:: . :.: :..:::.. :.::.::.:: :.:.::: . : ::
NP_002 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
100 110 120 130 140 150
100 110 120 130
pF1KE6 NDRLTCIQKGEKKNRGWTHWIEGDKLHLEMFCEGQVCKQTFQRA
.:.: :.:::::..::::.:::::.::::: :: ::::.:..
NP_002 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
160 170 180 190
>>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa)
initn: 558 init1: 545 opt: 556 Z-score: 760.4 bits: 146.4 E(85289): 1.3e-35
Smith-Waterman score: 556; 59.4% identity (80.5% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
: : .::: . :..:::::: :: ::::::::: : :::.:.::.: .:.:..::
NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
: : : :: :::: ...::::. :.:: :..: :.:.:::::.:::: .:::::::.::.
NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
70 80 90 100 110 120
130
pF1KE6 FCEGQVCKQTFQRA
: :::.:.:..
NP_004 TCGDQVCRQVFKKK
130
>>NP_113679 (OMIM: 611866) retinol-binding protein 5 iso (135 aa)
initn: 498 init1: 485 opt: 485 Z-score: 664.6 bits: 128.7 E(85289): 2.8e-30
Smith-Waterman score: 485; 49.6% identity (82.7% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
:: .:.: . ..:. :.: :. ::.:..:.:::: ::::.: ::..:. .:..: :..::
NP_113 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
: :.: :: ::.:: :..:.:::...: :....:.:.:::: :::: ::.::. :.::.
NP_113 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
70 80 90 100 110 120
130
pF1KE6 FCEGQVCKQTFQRA
. ::.:.:..
NP_113 TARDAVCEQVFRKVR
130
>>XP_016875491 (OMIM: 611866) PREDICTED: retinol-binding (126 aa)
initn: 418 init1: 405 opt: 416 Z-score: 572.1 bits: 111.5 E(85289): 4e-25
Smith-Waterman score: 416; 51.9% identity (84.3% similar) in 108 aa overlap (26-133:17-124)
10 20 30 40 50 60
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
:..:.:::: ::::.: ::..:. .:..: :..::
XP_016 MMNQAQWILKPGTMADISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
: :.: :: ::.:: :..:.:::...: :....:.:.:::: :::: ::.::. :.::.
XP_016 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
60 70 80 90 100 110
130
pF1KE6 FCEGQVCKQTFQRA
. ::.:.:..
XP_016 TARDAVCEQVFRKVR
120
>>NP_001316383 (OMIM: 611866) retinol-binding protein 5 (86 aa)
initn: 330 init1: 317 opt: 335 Z-score: 465.3 bits: 91.2 E(85289): 3.5e-19
Smith-Waterman score: 335; 50.6% identity (83.1% similar) in 83 aa overlap (51-133:2-84)
30 40 50 60 70 80
pF1KE6 MLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRNYFVKFKVGEEFDEDNRGLDN
:..: :..::: :.: :: ::.:: :..:.
NP_001 MTVRTLSTFRNYTVQFDVGVEFEEDLRSVDG
10 20 30
90 100 110 120 130
pF1KE6 RKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEMFCEGQVCKQTFQRA
:::...: :....:.:.:::: :::: ::.::. :.::. . ::.:.:..
NP_001 RKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
40 50 60 70 80
>>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa)
initn: 338 init1: 250 opt: 319 Z-score: 440.9 bits: 87.3 E(85289): 8e-18
Smith-Waterman score: 319; 39.4% identity (70.1% similar) in 127 aa overlap (7-133:7-131)
10 20 30 40 50 60
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
::: :..: ::. :: .::. ::::..:.. :: .::.::: .:..:.:...:
NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
..::.: :::: . :.:: ::.: :. .:. .:: . .. .. . :: : .
NP_004 TEISFKLGVEFDETT--ADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTL
70 80 90 100 110
130
pF1KE6 FCEGQVCKQTFQRA
:: .:...
NP_004 THGTAVCTRTYEKEA
120 130
>>NP_001186652 (OMIM: 180231) cellular retinoic acid-bin (138 aa)
initn: 296 init1: 147 opt: 314 Z-score: 433.9 bits: 86.0 E(85289): 2e-17
Smith-Waterman score: 314; 39.3% identity (69.3% similar) in 140 aa overlap (1-133:1-137)
10 20 30 40 50
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIA--KLLKPQKVIEQNGDSFTIHTNSSL
:: ..::.: .. :.::: . .::.. :::: :: :.:.::.: :.:....
NP_001 MP-NFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 RNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWDND-RLTCIQK---GEKKNRGWTHWIEGD
:. ..:::::::.:.. .:.: ::::: :... ...: :: :: . .::. . .:
NP_001 RTTEINFKVGEEFEEQT--VDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KE6 -KLHLEMFCEGQVCKQTFQRA
.: : : . :: ... :
NP_001 GELILTMTADDVVCTRVYVRE
120 130
>>XP_016855832 (OMIM: 180231) PREDICTED: cellular retino (138 aa)
initn: 296 init1: 147 opt: 314 Z-score: 433.9 bits: 86.0 E(85289): 2e-17
Smith-Waterman score: 314; 39.3% identity (69.3% similar) in 140 aa overlap (1-133:1-137)
10 20 30 40 50
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIA--KLLKPQKVIEQNGDSFTIHTNSSL
:: ..::.: .. :.::: . .::.. :::: :: :.:.::.: :.:....
XP_016 MP-NFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 RNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWDND-RLTCIQK---GEKKNRGWTHWIEGD
:. ..:::::::.:.. .:.: ::::: :... ...: :: :: . .::. . .:
XP_016 RTTEINFKVGEEFEEQT--VDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KE6 -KLHLEMFCEGQVCKQTFQRA
.: : : . :: ... :
XP_016 GELILTMTADDVVCTRVYVRE
120 130
>>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa)
initn: 296 init1: 147 opt: 314 Z-score: 433.9 bits: 86.0 E(85289): 2e-17
Smith-Waterman score: 314; 39.3% identity (69.3% similar) in 140 aa overlap (1-133:1-137)
10 20 30 40 50
pF1KE6 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIA--KLLKPQKVIEQNGDSFTIHTNSSL
:: ..::.: .. :.::: . .::.. :::: :: :.:.::.: :.:....
NP_001 MP-NFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 RNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWDND-RLTCIQK---GEKKNRGWTHWIEGD
:. ..:::::::.:.. .:.: ::::: :... ...: :: :: . .::. . .:
NP_001 RTTEINFKVGEEFEEQT--VDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KE6 -KLHLEMFCEGQVCKQTFQRA
.: : : . :: ... :
NP_001 GELILTMTADDVVCTRVYVRE
120 130
134 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:01:13 2016 done: Tue Nov 8 10:01:13 2016
Total Scan time: 2.850 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]