Result of FASTA (omim) for
pFN21AE6162
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6162, 172 aa
1>>>pF1KE6162 172 - 172 aa - 172 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4897+/-0.000247; mu= 13.8147+/- 0.016
mean_var=90.0283+/-17.713, 0's: 0 Z-trim(123.3): 12 B-trim: 0 in 0/55
Lambda= 0.135171
statistics sampled from 42979 (42991) to 42979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.504), width: 16
Scan time: 4.390
The best scores are: opt bits E(85289)
NP_848932 (OMIM: 607398,609196) melanocortin-2 rec ( 172) 1194 241.3 5.8e-64
XP_006724091 (OMIM: 607398,609196) PREDICTED: mela ( 172) 1194 241.3 5.8e-64
NP_001272323 (OMIM: 607398,609196) melanocortin-2 ( 113) 815 167.2 7.5e-42
NP_996781 (OMIM: 607398,609196) melanocortin-2 rec ( 102) 448 95.6 2.4e-20
XP_016883896 (OMIM: 607398,609196) PREDICTED: mela ( 102) 448 95.6 2.4e-20
XP_016865709 (OMIM: 615410,615457) PREDICTED: mela ( 205) 189 45.4 6.5e-05
NP_612418 (OMIM: 615410,615457) melanocortin-2 rec ( 205) 189 45.4 6.5e-05
NP_001333471 (OMIM: 615410,615457) melanocortin-2 ( 205) 189 45.4 6.5e-05
NP_001333473 (OMIM: 615410,615457) melanocortin-2 ( 205) 189 45.4 6.5e-05
XP_016865710 (OMIM: 615410,615457) PREDICTED: mela ( 154) 185 44.5 9e-05
>>NP_848932 (OMIM: 607398,609196) melanocortin-2 recepto (172 aa)
initn: 1194 init1: 1194 opt: 1194 Z-score: 1269.4 bits: 241.3 E(85289): 5.8e-64
Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSRTGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSRTGPD
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QPLRQESSSTLPLGGFQTHPTLLWELTLNGGPLVRSKPSEPPPGDRTSQLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 QPLRQESSSTLPLGGFQTHPTLLWELTLNGGPLVRSKPSEPPPGDRTSQLQS
130 140 150 160 170
>>XP_006724091 (OMIM: 607398,609196) PREDICTED: melanoco (172 aa)
initn: 1194 init1: 1194 opt: 1194 Z-score: 1269.4 bits: 241.3 E(85289): 5.8e-64
Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSRTGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSRTGPD
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QPLRQESSSTLPLGGFQTHPTLLWELTLNGGPLVRSKPSEPPPGDRTSQLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPLRQESSSTLPLGGFQTHPTLLWELTLNGGPLVRSKPSEPPPGDRTSQLQS
130 140 150 160 170
>>NP_001272323 (OMIM: 607398,609196) melanocortin-2 rece (113 aa)
initn: 815 init1: 815 opt: 815 Z-score: 872.4 bits: 167.2 E(85289): 7.5e-42
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 113 aa overlap (60-172:1-113)
30 40 50 60 70 80
pF1KE6 KLKAHKHSIVIAFWVSLAAFVVLLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLC
::::::::::::::::::::::::::::::
NP_001 MSWSASPQMRNSPKHHQTCPWSHGLNLHLC
10 20 30
90 100 110 120 130 140
pF1KE6 IQKCLPCHREPLATSQAQASSVEPGSRTGPDQPLRQESSSTLPLGGFQTHPTLLWELTLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQKCLPCHREPLATSQAQASSVEPGSRTGPDQPLRQESSSTLPLGGFQTHPTLLWELTLN
40 50 60 70 80 90
150 160 170
pF1KE6 GGPLVRSKPSEPPPGDRTSQLQS
:::::::::::::::::::::::
NP_001 GGPLVRSKPSEPPPGDRTSQLQS
100 110
>>NP_996781 (OMIM: 607398,609196) melanocortin-2 recepto (102 aa)
initn: 445 init1: 445 opt: 448 Z-score: 486.2 bits: 95.6 E(85289): 2.4e-20
Smith-Waterman score: 448; 79.8% identity (89.9% similar) in 89 aa overlap (1-85:1-89)
10 20 30 40 50 60
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 SWSASPQMR-NSPK---HHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSR
:::::::: :. . : .. : .....
NP_996 SWSASPQMSFNTDESLLHSEVLPQTRAISCDELQAPREEGAA
70 80 90 100
>>XP_016883896 (OMIM: 607398,609196) PREDICTED: melanoco (102 aa)
initn: 445 init1: 445 opt: 448 Z-score: 486.2 bits: 95.6 E(85289): 2.4e-20
Smith-Waterman score: 448; 79.8% identity (89.9% similar) in 89 aa overlap (1-85:1-89)
10 20 30 40 50 60
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYM
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 SWSASPQMR-NSPK---HHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSR
:::::::: :. . : .. : .....
XP_016 SWSASPQMSFNTDESLLHSEVLPQTRAISCDELQAPREEGAA
70 80 90 100
>>XP_016865709 (OMIM: 615410,615457) PREDICTED: melanoco (205 aa)
initn: 216 init1: 182 opt: 189 Z-score: 209.2 bits: 45.4 E(85289): 6.5e-05
Smith-Waterman score: 189; 42.4% identity (80.3% similar) in 66 aa overlap (6-71:15-78)
10 20 30 40 50
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVV
.:: :..:: .: .. ::. . :::::.::::.:::.::.::.
XP_016 MSAQRLISNRTSQQSASNSDYTWEY--EYYEIGPVSFEGLKAHKYSIVIGFWVGLAVFVI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSV
..:..: .. ...:.. :.
XP_016 FMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGRPLEPDKVFSRQGNEESRSLFHC
60 70 80 90 100 110
>>NP_612418 (OMIM: 615410,615457) melanocortin-2 recepto (205 aa)
initn: 216 init1: 182 opt: 189 Z-score: 209.2 bits: 45.4 E(85289): 6.5e-05
Smith-Waterman score: 189; 42.4% identity (80.3% similar) in 66 aa overlap (6-71:15-78)
10 20 30 40 50
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVV
.:: :..:: .: .. ::. . :::::.::::.:::.::.::.
NP_612 MSAQRLISNRTSQQSASNSDYTWEY--EYYEIGPVSFEGLKAHKYSIVIGFWVGLAVFVI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSV
..:..: .. ...:.. :.
NP_612 FMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGRPLEPDKVFSRQGNEESRSLFHC
60 70 80 90 100 110
>>NP_001333471 (OMIM: 615410,615457) melanocortin-2 rece (205 aa)
initn: 216 init1: 182 opt: 189 Z-score: 209.2 bits: 45.4 E(85289): 6.5e-05
Smith-Waterman score: 189; 42.4% identity (80.3% similar) in 66 aa overlap (6-71:15-78)
10 20 30 40 50
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVV
.:: :..:: .: .. ::. . :::::.::::.:::.::.::.
NP_001 MSAQRLISNRTSQQSASNSDYTWEY--EYYEIGPVSFEGLKAHKYSIVIGFWVGLAVFVI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSV
..:..: .. ...:.. :.
NP_001 FMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGRPLEPDKVFSRQGNEESRSLFHC
60 70 80 90 100 110
>>NP_001333473 (OMIM: 615410,615457) melanocortin-2 rece (205 aa)
initn: 216 init1: 182 opt: 189 Z-score: 209.2 bits: 45.4 E(85289): 6.5e-05
Smith-Waterman score: 189; 42.4% identity (80.3% similar) in 66 aa overlap (6-71:15-78)
10 20 30 40 50
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVV
.:: :..:: .: .. ::. . :::::.::::.:::.::.::.
NP_001 MSAQRLISNRTSQQSASNSDYTWEY--EYYEIGPVSFEGLKAHKYSIVIGFWVGLAVFVI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSV
..:..: .. ...:.. :.
NP_001 FMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGRPLEPDKVFSRQGNEESRSLFHC
60 70 80 90 100 110
>>XP_016865710 (OMIM: 615410,615457) PREDICTED: melanoco (154 aa)
initn: 194 init1: 176 opt: 185 Z-score: 206.6 bits: 44.5 E(85289): 9e-05
Smith-Waterman score: 185; 37.0% identity (74.1% similar) in 81 aa overlap (6-86:15-91)
10 20 30 40 50
pF1KE6 MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVV
.:: :..:: .: .. ::. . :::::.::::.:::.::.::.
XP_016 MSAQRLISNRTSQQSASNSDYTWEY--EYYEIGPVSFEGLKAHKYSIVIGFWVGLAVFVI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSV
..:..: .. ...:.. . ... : : . :.
XP_016 FMFFVLTLLTKTGAPHQDGLSQQELT--WVEKKNFSFLTVFGNADGTFWDTPSTLEPADE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 EPGSRTGPDQPLRQESSSTLPLGGFQTHPTLLWELTLNGGPLVRSKPSEPPPGDRTSQLQ
XP_016 ILAKLAEAGKRKIHGKHSDKYRLLITSRSYHLARNASY
120 130 140 150
172 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:58:46 2016 done: Tue Nov 8 09:58:47 2016
Total Scan time: 4.390 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]