Result of FASTA (omim) for
pFN21AE6156
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6156, 132 aa
1>>>pF1KE6156 132 - 132 aa - 132 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3377+/-0.000332; mu= 10.1498+/- 0.021
mean_var=57.6328+/-11.391, 0's: 0 Z-trim(114.9): 31 B-trim: 248 in 1/56
Lambda= 0.168943
statistics sampled from 24908 (24939) to 24908 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.292), width: 16
Scan time: 4.750
The best scores are: opt bits E(85289)
NP_006489 (OMIM: 150571,608446) galectin-2 [Homo s ( 132) 892 225.3 2.3e-59
NP_002296 (OMIM: 150570) galectin-1 [Homo sapiens] ( 135) 391 103.2 1.3e-22
NP_002297 (OMIM: 153619) galectin-3 isoform 1 [Hom ( 250) 236 65.5 5.5e-11
XP_011535061 (OMIM: 153619) PREDICTED: galectin-3 ( 264) 236 65.5 5.7e-11
NP_001035972 (OMIM: 617139) galectin-7 [Homo sapie ( 136) 210 59.1 2.6e-09
NP_002298 (OMIM: 600615) galectin-7 [Homo sapiens] ( 136) 210 59.1 2.6e-09
XP_016856764 (OMIM: 606099) PREDICTED: galectin-8 ( 226) 210 59.1 4e-09
NP_963838 (OMIM: 606099) galectin-8 isoform b [Hom ( 317) 192 54.8 1.1e-07
NP_963837 (OMIM: 606099) galectin-8 isoform b [Hom ( 317) 192 54.8 1.1e-07
XP_011525276 (OMIM: 602518) PREDICTED: galectin-4 ( 192) 189 54.0 1.2e-07
NP_963839 (OMIM: 606099) galectin-8 isoform a [Hom ( 359) 192 54.8 1.3e-07
NP_006490 (OMIM: 606099) galectin-8 isoform a [Hom ( 359) 192 54.8 1.3e-07
XP_011525275 (OMIM: 602518) PREDICTED: galectin-4 ( 310) 189 54.1 1.9e-07
NP_006140 (OMIM: 602518) galectin-4 [Homo sapiens] ( 323) 189 54.1 1.9e-07
XP_006721958 (OMIM: 601879) PREDICTED: galectin-9 ( 234) 187 53.5 2e-07
XP_011523098 (OMIM: 601879) PREDICTED: galectin-9 ( 221) 186 53.3 2.3e-07
NP_001317092 (OMIM: 601879) galectin-9 isoform 3 [ ( 246) 186 53.3 2.5e-07
XP_006721955 (OMIM: 601879) PREDICTED: galectin-9 ( 311) 187 53.6 2.6e-07
XP_006721956 (OMIM: 601879) PREDICTED: galectin-9 ( 278) 186 53.3 2.8e-07
NP_002299 (OMIM: 601879) galectin-9 isoform short ( 323) 186 53.3 3.2e-07
XP_016880112 (OMIM: 601879) PREDICTED: galectin-9 ( 343) 186 53.3 3.4e-07
NP_033665 (OMIM: 601879) galectin-9 isoform long [ ( 355) 186 53.3 3.5e-07
XP_016873947 (OMIM: 606096) PREDICTED: galectin-12 ( 252) 182 52.3 5e-07
NP_001136008 (OMIM: 606096) galectin-12 isoform 3 ( 327) 182 52.4 6.4e-07
NP_149092 (OMIM: 606096) galectin-12 isoform 2 [Ho ( 336) 182 52.4 6.5e-07
NP_001136007 (OMIM: 606096) galectin-12 isoform 1 ( 337) 182 52.4 6.6e-07
NP_001136010 (OMIM: 606096) galectin-12 isoform 5 ( 266) 180 51.8 7.4e-07
NP_001136009 (OMIM: 606096) galectin-12 isoform 4 ( 275) 180 51.8 7.7e-07
XP_016856763 (OMIM: 606099) PREDICTED: galectin-8 ( 287) 153 45.3 7.6e-05
XP_011542490 (OMIM: 606099) PREDICTED: galectin-8 ( 329) 153 45.3 8.6e-05
>>NP_006489 (OMIM: 150571,608446) galectin-2 [Homo sapie (132 aa)
initn: 892 init1: 892 opt: 892 Z-score: 1186.9 bits: 225.3 E(85289): 2.3e-59
Smith-Waterman score: 892; 100.0% identity (100.0% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVR
70 80 90 100 110 120
130
pF1KE6 GGFNMSSFKLKE
::::::::::::
NP_006 GGFNMSSFKLKE
130
>>NP_002296 (OMIM: 150570) galectin-1 [Homo sapiens] (135 aa)
initn: 236 init1: 236 opt: 391 Z-score: 526.8 bits: 103.2 E(85289): 1.3e-22
Smith-Waterman score: 391; 44.2% identity (73.6% similar) in 129 aa overlap (1-125:1-129)
10 20 30 40 50
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSE----STIV
:. : ..:...::: :.. : .: . .::.:::. ...: :::::::. .:::
NP_002 MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 CNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSY
::: ::. :: :::: . :.::: .. .::.. .. ::::::.:. :::::. ..:
NP_002 CNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINY
70 80 90 100 110 120
120 130
pF1KE6 LSVRGGFNMSSFKLKE
... : :..
NP_002 MAADGDFKIKCVAFD
130
>>NP_002297 (OMIM: 153619) galectin-3 isoform 1 [Homo sa (250 aa)
initn: 192 init1: 146 opt: 236 Z-score: 318.3 bits: 65.5 E(85289): 5.5e-11
Smith-Waterman score: 236; 32.2% identity (68.6% similar) in 118 aa overlap (14-127:128-244)
10 20 30 40
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLN
: . : :.. ... ..... .:.: .
NP_002 TGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGND-VA
100 110 120 130 140 150
50 60 70 80 90 100
pF1KE6 LHFNPRFSEST---IVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDG
.::::::.:.. ::::. .:::.:.:.. . : :. :. : : :.::: . :.
NP_002 FHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDA
160 170 180 190 200 210
110 120 130
pF1KE6 HELTFPNRLGH-SHLSYLSVRGGFNMSSFKLKE
: : . .:. . ...: :.. : ....:
NP_002 HLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
220 230 240 250
>>XP_011535061 (OMIM: 153619) PREDICTED: galectin-3 isof (264 aa)
initn: 192 init1: 146 opt: 236 Z-score: 317.9 bits: 65.5 E(85289): 5.7e-11
Smith-Waterman score: 236; 32.2% identity (68.6% similar) in 118 aa overlap (14-127:142-258)
10 20 30 40
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLN
: . : :.. ... ..... .:.: .
XP_011 TGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGND-VA
120 130 140 150 160 170
50 60 70 80 90 100
pF1KE6 LHFNPRFSEST---IVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDG
.::::::.:.. ::::. .:::.:.:.. . : :. :. : : :.::: . :.
XP_011 FHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDA
180 190 200 210 220 230
110 120 130
pF1KE6 HELTFPNRLGH-SHLSYLSVRGGFNMSSFKLKE
: : . .:. . ...: :.. : ....:
XP_011 HLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
240 250 260
>>NP_001035972 (OMIM: 617139) galectin-7 [Homo sapiens] (136 aa)
initn: 194 init1: 143 opt: 210 Z-score: 288.3 bits: 59.1 E(85289): 2.6e-09
Smith-Waterman score: 210; 30.9% identity (62.6% similar) in 123 aa overlap (12-130:14-135)
10 20 30 40 50
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINL--G--QGTDKLNLHFNPRFSEST
..::..:.: : . ... : .:: : ::.: ::::::.. :
NP_001 MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDA-ALHFNPRLDTSE
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHL
.: :: . ..::.:.: . :. :. . . .: ::. . :.. : .:: ...
NP_001 VVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARV
60 70 80 90 100 110
120 130
pF1KE6 SYLSVRGGFNMSSFKLKE
. : : ...: ..
NP_001 RLVEVGGDVQLDSVRIF
120 130
>>NP_002298 (OMIM: 600615) galectin-7 [Homo sapiens] (136 aa)
initn: 194 init1: 143 opt: 210 Z-score: 288.3 bits: 59.1 E(85289): 2.6e-09
Smith-Waterman score: 210; 30.9% identity (62.6% similar) in 123 aa overlap (12-130:14-135)
10 20 30 40 50
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINL--G--QGTDKLNLHFNPRFSEST
..::..:.: : . ... : .:: : ::.: ::::::.. :
NP_002 MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDA-ALHFNPRLDTSE
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHL
.: :: . ..::.:.: . :. :. . . .: ::. . :.. : .:: ...
NP_002 VVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARV
60 70 80 90 100 110
120 130
pF1KE6 SYLSVRGGFNMSSFKLKE
. : : ...: ..
NP_002 RLVEVGGDVQLDSVRIF
120 130
>>XP_016856764 (OMIM: 606099) PREDICTED: galectin-8 isof (226 aa)
initn: 129 init1: 79 opt: 210 Z-score: 284.7 bits: 59.1 E(85289): 4e-09
Smith-Waterman score: 210; 28.7% identity (60.7% similar) in 122 aa overlap (12-127:27-148)
10 20 30 40
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTD-----
. ::. . : : . . .: : ..: .:..
XP_016 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA
10 20 30 40 50 60
50 60 70 80 90
pF1KE6 KLNLHFNPRFSES-TIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPD
. .::::::... ::::.: . .::.:. :. . .... .:::.: .
XP_016 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG
70 80 90 100 110 120
100 110 120 130
pF1KE6 GHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE
: : . .:.: ... :.. : :. :
XP_016 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT
130 140 150 160 170 180
>>NP_963838 (OMIM: 606099) galectin-8 isoform b [Homo sa (317 aa)
initn: 153 init1: 86 opt: 192 Z-score: 258.6 bits: 54.8 E(85289): 1.1e-07
Smith-Waterman score: 210; 28.7% identity (60.7% similar) in 122 aa overlap (12-127:27-148)
10 20 30 40
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTD-----
. ::. . : : . . .: : ..: .:..
NP_963 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA
10 20 30 40 50 60
50 60 70 80 90
pF1KE6 KLNLHFNPRFSES-TIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPD
. .::::::... ::::.: . .::.:. :. . .... .:::.: .
NP_963 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG
70 80 90 100 110 120
100 110 120 130
pF1KE6 GHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE
: : . .:.: ... :.. : :. :
NP_963 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT
130 140 150 160 170 180
>--
initn: 153 init1: 86 opt: 192 Z-score: 258.6 bits: 54.8 E(85289): 1.1e-07
Smith-Waterman score: 192; 29.2% identity (60.8% similar) in 120 aa overlap (9-125:192-311)
10 20 30
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQG
: : :: :. . : . .. .: ..: :
NP_963 ASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAG
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE6 TDK-LNLHFNPRFSESTIVCNSLDGSNWGQEQRE-DHLCFSPGSEVKFTVTFESDKFKVK
.: . ::.:::.. ...: ::. .::.:.:. . :::: .. . . .:::
NP_963 KSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVA
230 240 250 260 270 280
100 110 120 130
pF1KE6 LPDGHELTFPNRLGH-SHLSYLSVRGGFNMSSFKLKE
. : : . .:. . : .. : . : ...
NP_963 VNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
290 300 310
>>NP_963837 (OMIM: 606099) galectin-8 isoform b [Homo sa (317 aa)
initn: 153 init1: 86 opt: 192 Z-score: 258.6 bits: 54.8 E(85289): 1.1e-07
Smith-Waterman score: 210; 28.7% identity (60.7% similar) in 122 aa overlap (12-127:27-148)
10 20 30 40
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTD-----
. ::. . : : . . .: : ..: .:..
NP_963 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA
10 20 30 40 50 60
50 60 70 80 90
pF1KE6 KLNLHFNPRFSES-TIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPD
. .::::::... ::::.: . .::.:. :. . .... .:::.: .
NP_963 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG
70 80 90 100 110 120
100 110 120 130
pF1KE6 GHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE
: : . .:.: ... :.. : :. :
NP_963 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT
130 140 150 160 170 180
>--
initn: 153 init1: 86 opt: 192 Z-score: 258.6 bits: 54.8 E(85289): 1.1e-07
Smith-Waterman score: 192; 29.2% identity (60.8% similar) in 120 aa overlap (9-125:192-311)
10 20 30
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQG
: : :: :. . : . .. .: ..: :
NP_963 ASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAG
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE6 TDK-LNLHFNPRFSESTIVCNSLDGSNWGQEQRE-DHLCFSPGSEVKFTVTFESDKFKVK
.: . ::.:::.. ...: ::. .::.:.:. . :::: .. . . .:::
NP_963 KSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVA
230 240 250 260 270 280
100 110 120 130
pF1KE6 LPDGHELTFPNRLGH-SHLSYLSVRGGFNMSSFKLKE
. : : . .:. . : .. : . : ...
NP_963 VNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
290 300 310
>>XP_011525276 (OMIM: 602518) PREDICTED: galectin-4 isof (192 aa)
initn: 98 init1: 98 opt: 189 Z-score: 258.2 bits: 54.0 E(85289): 1.2e-07
Smith-Waterman score: 189; 29.9% identity (64.1% similar) in 117 aa overlap (17-130:76-192)
10 20 30 40
pF1KE6 MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTD-KLNLH
:. : : . .:.::. :.. . ::
XP_011 NSLPTMEGPPTFNPPVPYFGRLQGGLTARRTIIIKGYVPPTGKSFAINFKVGSSGDIALH
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE6 FNPRFSESTIVCNSLDGSNWGQEQRE-DHLCFSPGSEVKFTVTFESDKFKVKLPDGHELT
.:::....:.: ::: ...::.:... : :.::. ... :.::: : .
XP_011 INPRMGNGTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFD
110 120 130 140 150 160
110 120 130
pF1KE6 FPNRLG-HSHLSYLSVRGGFNMSSFKLKE
: .::. .... : ..: ..: ..
XP_011 FAHRLSAFQRVDTLEIQGDVTLSYVQI
170 180 190
132 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:56:23 2016 done: Tue Nov 8 09:56:24 2016
Total Scan time: 4.750 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]