Result of FASTA (omim) for
pFN21AE6140
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6140, 170 aa
1>>>pF1KE6140 170 - 170 aa - 170 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5303+/-0.000263; mu= 7.7042+/- 0.017
mean_var=94.2319+/-18.500, 0's: 0 Z-trim(121.6): 16 B-trim: 0 in 0/60
Lambda= 0.132122
statistics sampled from 38500 (38516) to 38500 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.452), width: 16
Scan time: 6.210
The best scores are: opt bits E(85289)
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170) 1108 220.1 1.3e-57
XP_011539552 (OMIM: 610692) PREDICTED: heat shock ( 262) 1090 216.8 2.1e-56
XP_011539551 (OMIM: 610692) PREDICTED: heat shock ( 263) 1088 216.4 2.7e-56
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182) 187 44.6 9.9e-05
NP_055180 (OMIM: 158590,608014,608673) heat shock ( 196) 180 43.3 0.00027
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175) 178 42.9 0.00032
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175) 178 42.9 0.00032
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175) 178 42.9 0.00032
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175) 178 42.9 0.00032
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160) 175 42.3 0.00043
NP_001531 (OMIM: 602195,606595,608634) heat shock ( 205) 168 41.0 0.0014
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108) 163 39.9 0.0015
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136) 154 38.2 0.006
>>NP_055239 (OMIM: 610692) heat shock protein beta-7 [Ho (170 aa)
initn: 1108 init1: 1108 opt: 1108 Z-score: 1155.1 bits: 220.1 E(85289): 1.3e-57
Smith-Waterman score: 1108; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KE6 MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMN
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 TFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
130 140 150 160 170
>>XP_011539552 (OMIM: 610692) PREDICTED: heat shock prot (262 aa)
initn: 718 init1: 718 opt: 1090 Z-score: 1133.7 bits: 216.8 E(85289): 2.1e-56
Smith-Waterman score: 1090; 97.7% identity (97.7% similar) in 174 aa overlap (1-170:89-262)
10 20 30
pF1KE6 MSHRTSSTFRAERSFHSSSSSSSSSTSSSA
::::::::::::::::::::::::::::::
XP_011 GAWHARPEACAHTLSCPALARLGRARRRPWMSHRTSSTFRAERSFHSSSSSSSSSTSSSA
60 70 80 90 100 110
40 50 60 70 80
pF1KE6 SRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPA----RPGGAGNIKTLGDAYEFAV
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 SRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPAHPTARPGGAGNIKTLGDAYEFAV
120 130 140 150 160 170
90 100 110 120 130 140
pF1KE6 DVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGS
180 190 200 210 220 230
150 160 170
pF1KE6 LTIRARRHPHTEHVQQTFRTEIKI
::::::::::::::::::::::::
XP_011 LTIRARRHPHTEHVQQTFRTEIKI
240 250 260
>>XP_011539551 (OMIM: 610692) PREDICTED: heat shock prot (263 aa)
initn: 679 init1: 679 opt: 1088 Z-score: 1131.6 bits: 216.4 E(85289): 2.7e-56
Smith-Waterman score: 1088; 97.1% identity (97.1% similar) in 175 aa overlap (1-170:89-263)
10 20 30
pF1KE6 MSHRTSSTFRAERSFHSSSSSSSSSTSSSA
::::::::::::::::::::::::::::::
XP_011 GAWHARPEACAHTLSCPALARLGRARRRPWMSHRTSSTFRAERSFHSSSSSSSSSTSSSA
60 70 80 90 100 110
40 50 60 70 80
pF1KE6 SRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPA-----RPGGAGNIKTLGDAYEFA
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 SRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPAAHPTARPGGAGNIKTLGDAYEFA
120 130 140 150 160 170
90 100 110 120 130 140
pF1KE6 VDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDG
180 190 200 210 220 230
150 160 170
pF1KE6 SLTIRARRHPHTEHVQQTFRTEIKI
:::::::::::::::::::::::::
XP_011 SLTIRARRHPHTEHVQQTFRTEIKI
240 250 260
>>NP_001532 (OMIM: 602179) heat shock protein beta-2 [Ho (182 aa)
initn: 166 init1: 84 opt: 187 Z-score: 205.9 bits: 44.6 E(85289): 9.9e-05
Smith-Waterman score: 187; 33.9% identity (58.9% similar) in 112 aa overlap (53-158:46-156)
30 40 50 60 70 80
pF1KE6 SSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARPGGAGNIKTLGDAY
: ..::.. : . .: .::.... .
NP_001 YEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSR-AGASELRLSEGKF
20 30 40 50 60 70
90 100 110 120 130
pF1KE6 EFAVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKCQLPEDVDPTSVTS
. .:: :.:... : : .: .:: : ..: : : : . :: :::: : .
NP_001 QAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRA
80 90 100 110 120 130
140 150 160 170
pF1KE6 ALREDGSLTI---RARRHPHTEHVQQTFRTEIKI
:: .:: :.. :. :: ::
NP_001 ALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP
140 150 160 170 180
>>NP_055180 (OMIM: 158590,608014,608673) heat shock prot (196 aa)
initn: 189 init1: 106 opt: 180 Z-score: 198.2 bits: 43.3 E(85289): 0.00027
Smith-Waterman score: 180; 33.0% identity (70.2% similar) in 94 aa overlap (79-168:93-186)
50 60 70 80 90 100
pF1KE6 SDDFGSFMRPHSEPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVR
:. .. :.:..:.::...: :.....::
NP_055 TLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 A---EKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARR-HPHTEHVQQTF
. :: : : ..:..: ::: .:::..: ..: .: : :.: . :.. ...:
NP_055 GKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSF
130 140 150 160 170 180
170
pF1KE6 RTEIKI
.:.
NP_055 NNELPQDSQEVTCT
190
>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 155 init1: 81 opt: 178 Z-score: 196.9 bits: 42.9 E(85289): 0.00032
Smith-Waterman score: 178; 32.5% identity (55.6% similar) in 117 aa overlap (40-153:39-149)
10 20 30 40 50 60
pF1KE6 RAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARP
: .:: : ::.: : : .
NP_001 WIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLR---APSWFDT--
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKC
: .... : . .::. ::::.. : . .. :::.. :. : . : .:
NP_001 -GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKY
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
..: :::: ..::.: :: ::. . :
NP_001 RIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 155 init1: 81 opt: 178 Z-score: 196.9 bits: 42.9 E(85289): 0.00032
Smith-Waterman score: 178; 32.5% identity (55.6% similar) in 117 aa overlap (40-153:39-149)
10 20 30 40 50 60
pF1KE6 RAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARP
: .:: : ::.: : : .
XP_011 WIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLR---APSWFDT--
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKC
: .... : . .::. ::::.. : . .. :::.. :. : . : .:
XP_011 -GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKY
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
..: :::: ..::.: :: ::. . :
XP_011 RIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 155 init1: 81 opt: 178 Z-score: 196.9 bits: 42.9 E(85289): 0.00032
Smith-Waterman score: 178; 32.5% identity (55.6% similar) in 117 aa overlap (40-153:39-149)
10 20 30 40 50 60
pF1KE6 RAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARP
: .:: : ::.: : : .
NP_001 WIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLR---APSWFDT--
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKC
: .... : . .::. ::::.. : . .. :::.. :. : . : .:
NP_001 -GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKY
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
..: :::: ..::.: :: ::. . :
NP_001 RIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a (175 aa)
initn: 155 init1: 81 opt: 178 Z-score: 196.9 bits: 42.9 E(85289): 0.00032
Smith-Waterman score: 178; 32.5% identity (55.6% similar) in 117 aa overlap (40-153:39-149)
10 20 30 40 50 60
pF1KE6 RAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARP
: .:: : ::.: : : .
NP_001 WIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLR---APSWFDT--
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKC
: .... : . .::. ::::.. : . .. :::.. :. : . : .:
NP_001 -GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKY
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI
..: :::: ..::.: :: ::. . :
NP_001 RIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
130 140 150 160 170
>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho (160 aa)
initn: 169 init1: 86 opt: 175 Z-score: 194.4 bits: 42.3 E(85289): 0.00043
Smith-Waterman score: 175; 36.0% identity (59.0% similar) in 100 aa overlap (55-151:54-146)
30 40 50 60 70 80
pF1KE6 STSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARPGGAGNIKTLGDAYEF
..: : : : :....:
NP_653 APGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPSVALPVAQVPTDPGHFSVL------
30 40 50 60 70
90 100 110 120 130 140
pF1KE6 AVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKCQLPEDVDPTSVTSAL
.::. ::::.: : . ..:.::.: :. : : : .. .:: :::..:::::
NP_653 -LDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSAL
80 90 100 110 120 130
150 160 170
pF1KE6 REDGSLTIRARRHPHTEHVQQTFRTEIKI
.: :.:.:
NP_653 SPEGVLSIQAAPASAQAPPPAAAK
140 150 160
170 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:48:30 2016 done: Tue Nov 8 09:48:31 2016
Total Scan time: 6.210 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]