FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6134, 143 aa
  1>>>pF1KE6134 143 - 143 aa - 143 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6112+/-0.000388; mu= 14.8093+/- 0.024
 mean_var=51.8852+/-10.546, 0's: 0 Z-trim(111.9): 12  B-trim: 650 in 1/52
 Lambda= 0.178054
 statistics sampled from 20568 (20575) to 20568 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.241), width:  16
 Scan time:  3.550

The best scores are:                                      opt bits E(85289)
NP_001851 (OMIM: 603088) probable low affinity cop ( 143)  931 246.7 9.7e-66
XP_011516518 (OMIM: 603088) PREDICTED: probable lo ( 141)  919 243.6 8.1e-65
XP_016869756 (OMIM: 603088) PREDICTED: probable lo ( 199)  920 243.9   9e-65
NP_001850 (OMIM: 603085) high affinity copper upta ( 190)  223 64.9 6.8e-11


>>NP_001851 (OMIM: 603088) probable low affinity copper   (143 aa)
 initn: 931 init1: 931 opt: 931  Z-score: 1301.2  bits: 246.7 E(85289): 9.7e-66
Smith-Waterman score: 931; 100.0% identity (100.0% similar) in 143 aa overlap (1-143:1-143)

               10        20        30        40        50        60
pF1KE6 MAMHFIFSDTAVLLFDFWSVHSPAGMALSVLVLLLLAVLYEGIKVGKAKLLNQVLVNLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAMHFIFSDTAVLLFDFWSVHSPAGMALSVLVLLLLAVLYEGIKVGKAKLLNQVLVNLPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 SISQQTIAETDGDSAGSDSFPVGRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISQQTIAETDGDSAGSDSFPVGRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTW
               70        80        90       100       110       120

              130       140   
pF1KE6 IFLGVVLGSAVGYYLAYPLLSTA
       :::::::::::::::::::::::
NP_001 IFLGVVLGSAVGYYLAYPLLSTA
              130       140   

>>XP_011516518 (OMIM: 603088) PREDICTED: probable low af  (141 aa)
 initn: 919 init1: 919 opt: 919  Z-score: 1284.7  bits: 243.6 E(85289): 8.1e-65
Smith-Waterman score: 919; 100.0% identity (100.0% similar) in 141 aa overlap (3-143:1-141)

               10        20        30        40        50        60
pF1KE6 MAMHFIFSDTAVLLFDFWSVHSPAGMALSVLVLLLLAVLYEGIKVGKAKLLNQVLVNLPT
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011   MHFIFSDTAVLLFDFWSVHSPAGMALSVLVLLLLAVLYEGIKVGKAKLLNQVLVNLPT
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KE6 SISQQTIAETDGDSAGSDSFPVGRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SISQQTIAETDGDSAGSDSFPVGRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTW
       60        70        80        90       100       110        

              130       140   
pF1KE6 IFLGVVLGSAVGYYLAYPLLSTA
       :::::::::::::::::::::::
XP_011 IFLGVVLGSAVGYYLAYPLLSTA
      120       130       140 

>>XP_016869756 (OMIM: 603088) PREDICTED: probable low af  (199 aa)
 initn: 920 init1: 920 opt: 920  Z-score: 1283.9  bits: 243.9 E(85289): 9e-65
Smith-Waterman score: 920; 99.3% identity (100.0% similar) in 142 aa overlap (2-143:58-199)

                                            10        20        30 
pF1KE6                              MAMHFIFSDTAVLLFDFWSVHSPAGMALSVL
                                     .:::::::::::::::::::::::::::::
XP_016 MAQLPDKMAANQICLPFHPHTDVCLHRNSFSMHFIFSDTAVLLFDFWSVHSPAGMALSVL
        30        40        50        60        70        80       

              40        50        60        70        80        90 
pF1KE6 VLLLLAVLYEGIKVGKAKLLNQVLVNLPTSISQQTIAETDGDSAGSDSFPVGRTHHRWYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLLLAVLYEGIKVGKAKLLNQVLVNLPTSISQQTIAETDGDSAGSDSFPVGRTHHRWYL
        90       100       110       120       130       140       

             100       110       120       130       140   
pF1KE6 CHFGQSLIHVIQVVIGYFIMLAVMSYNTWIFLGVVLGSAVGYYLAYPLLSTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHFGQSLIHVIQVVIGYFIMLAVMSYNTWIFLGVVLGSAVGYYLAYPLLSTA
       150       160       170       180       190         

>>NP_001850 (OMIM: 603085) high affinity copper uptake p  (190 aa)
 initn: 210 init1: 118 opt: 223  Z-score: 316.5  bits: 64.9 E(85289): 6.8e-11
Smith-Waterman score: 228; 33.6% identity (65.0% similar) in 143 aa overlap (1-135:43-174)

                                             10         20         
pF1KE6                               MAMHFIFSDTAV-LLFDFWSVHSPAGMALS
                                     : : : :.   : :::.   ... . :: .
NP_001 DSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMAGA
             20        30        40        50        60        70  

      30        40        50             60        70          80  
pF1KE6 VLVLLLLAVLYEGIKVGKAKLL--NQVLV---NLPTSISQQTIAETDGDSAGSD--SFPV
        ....:::..:::.:... .::  .:: .   ..:.   . ::      ..:..  ::: 
NP_001 FVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFP-
             80        90       100       110       120       130  

             90       100       110       120       130       140  
pF1KE6 GRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTWIFLGVVLGSAVGYYLAYPLLST
                 :. :...:.:::::.::.::  :.:: .. ..:. :...::.:       
NP_001 ----------HLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAV
                       140       150       160       170       180 

                
pF1KE6 A        
                
NP_001 VVDITEHCH
             190




143 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 09:45:33 2016 done: Tue Nov  8 09:45:34 2016
 Total Scan time:  3.550 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]