Result of FASTA (omim) for
pFN21AE6126
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6126, 105 aa
1>>>pF1KE6126 105 - 105 aa - 105 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1469+/-0.000273; mu= 10.8524+/- 0.017
mean_var=69.4089+/-13.527, 0's: 0 Z-trim(120.4): 38 B-trim: 63 in 1/51
Lambda= 0.153945
statistics sampled from 35502 (35546) to 35502 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.417), width: 16
Scan time: 3.240
The best scores are: opt bits E(85289)
NP_115790 (OMIM: 606233) prokineticin-1 precursor ( 105) 772 179.3 1e-45
NP_068754 (OMIM: 607002,610628) prokineticin-2 iso ( 108) 407 98.2 2.7e-21
NP_001119600 (OMIM: 607002,610628) prokineticin-2 ( 129) 269 67.6 5.2e-12
XP_016862463 (OMIM: 607002,610628) PREDICTED: prok ( 109) 233 59.6 1.2e-09
NP_055235 (OMIM: 605417) dickkopf-related protein ( 224) 160 43.6 0.00016
XP_011542790 (OMIM: 605417) PREDICTED: dickkopf-re ( 224) 160 43.6 0.00016
XP_016868805 (OMIM: 605417) PREDICTED: dickkopf-re ( 224) 160 43.6 0.00016
NP_055236 (OMIM: 605415) dickkopf-related protein ( 259) 148 40.9 0.0011
XP_016873044 (OMIM: 605416) PREDICTED: dickkopf-re ( 364) 148 41.0 0.0014
NP_001317149 (OMIM: 605416) dickkopf-related prote ( 364) 148 41.0 0.0014
XP_016873043 (OMIM: 605416) PREDICTED: dickkopf-re ( 364) 148 41.0 0.0014
NP_056965 (OMIM: 605416) dickkopf-related protein ( 350) 144 40.1 0.0026
NP_037385 (OMIM: 605416) dickkopf-related protein ( 350) 144 40.1 0.0026
XP_006718241 (OMIM: 605416) PREDICTED: dickkopf-re ( 350) 144 40.1 0.0026
NP_001018067 (OMIM: 605416) dickkopf-related prote ( 350) 144 40.1 0.0026
NP_036374 (OMIM: 605189) dickkopf-related protein ( 266) 140 39.2 0.0039
>>NP_115790 (OMIM: 606233) prokineticin-1 precursor [Hom (105 aa)
initn: 772 init1: 772 opt: 772 Z-score: 941.7 bits: 179.3 E(85289): 1e-45
Smith-Waterman score: 772; 99.0% identity (100.0% similar) in 105 aa overlap (1-105:1-105)
10 20 30 40 50 60
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEEC
10 20 30 40 50 60
70 80 90 100
pF1KE6 HPGSHKIPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
::::::.::::::::::::::::::::::::::::::::::::::
NP_115 HPGSHKVPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
70 80 90 100
>>NP_068754 (OMIM: 607002,610628) prokineticin-2 isoform (108 aa)
initn: 418 init1: 392 opt: 407 Z-score: 503.4 bits: 98.2 E(85289): 2.7e-21
Smith-Waterman score: 407; 54.0% identity (80.5% similar) in 87 aa overlap (10-96:18-104)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTP
.:: ..: :::::::..: :::.: :::.:.:....:.:::
NP_068 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
10 20 30 40 50 60
60 70 80 90 100
pF1KE6 LGREGEECHPGSHKIPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
.:. :. ::: ..:.::: .: ::::::::.: : : .:. :
NP_068 MGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK
70 80 90 100
>>NP_001119600 (OMIM: 607002,610628) prokineticin-2 isof (129 aa)
initn: 382 init1: 269 opt: 269 Z-score: 336.7 bits: 67.6 E(85289): 5.2e-12
Smith-Waterman score: 355; 43.5% identity (64.8% similar) in 108 aa overlap (10-96:18-125)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTP
.:: ..: :::::::..: :::.: :::.:.:....:.:::
NP_001 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
10 20 30 40 50 60
60 70 80 90
pF1KE6 LGREGEECHPGSHK---------------------IPFFRKRKHHTCPCLPNLLCSRFPD
.:. :. ::: ..: .::: .: ::::::::.: : :
NP_001 MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF
70 80 90 100 110 120
100
pF1KE6 GRYRCSMDLKNINF
.:. :
NP_001 NRFICLAQK
>>XP_016862463 (OMIM: 607002,610628) PREDICTED: prokinet (109 aa)
initn: 342 init1: 229 opt: 233 Z-score: 294.5 bits: 59.6 E(85289): 1.2e-09
Smith-Waterman score: 319; 39.0% identity (61.9% similar) in 105 aa overlap (13-96:1-105)
10 20 30 40 50 60
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEEC
. . : . : .::..: :::.: :::.:.:....:.:::.:. :. :
XP_016 MFKLRDDVFIFSACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSC
10 20 30 40
70 80 90
pF1KE6 HPGSHK---------------------IPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMD
:: ..: .::: .: ::::::::.: : : .:. :
XP_016 HPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQ
50 60 70 80 90 100
100
pF1KE6 LKNINF
XP_016 K
>>NP_055235 (OMIM: 605417) dickkopf-related protein 4 pr (224 aa)
initn: 130 init1: 74 opt: 160 Z-score: 202.4 bits: 43.6 E(85289): 0.00016
Smith-Waterman score: 160; 34.3% identity (55.7% similar) in 70 aa overlap (25-93:144-210)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLG
.: : .:: : ::: .: . .: :.
NP_055 GTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTK---ICKPVL
120 130 140 150 160 170
60 70 80 90 100
pF1KE6 REGEECHPGSHKIPFFRKRKHHTCPCLPNLLC-SRFPDGRYRCSMDLKNINF
::. : .:: . . : : :.::: :.. ..:
NP_055 LEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
180 190 200 210 220
>>XP_011542790 (OMIM: 605417) PREDICTED: dickkopf-relate (224 aa)
initn: 130 init1: 74 opt: 160 Z-score: 202.4 bits: 43.6 E(85289): 0.00016
Smith-Waterman score: 160; 34.3% identity (55.7% similar) in 70 aa overlap (25-93:144-210)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLG
.: : .:: : ::: .: . .: :.
XP_011 GTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTK---ICKPVL
120 130 140 150 160 170
60 70 80 90 100
pF1KE6 REGEECHPGSHKIPFFRKRKHHTCPCLPNLLC-SRFPDGRYRCSMDLKNINF
::. : .:: . . : : :.::: :.. ..:
XP_011 LEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
180 190 200 210 220
>>XP_016868805 (OMIM: 605417) PREDICTED: dickkopf-relate (224 aa)
initn: 130 init1: 74 opt: 160 Z-score: 202.4 bits: 43.6 E(85289): 0.00016
Smith-Waterman score: 160; 34.3% identity (55.7% similar) in 70 aa overlap (25-93:144-210)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLG
.: : .:: : ::: .: . .: :.
XP_016 GTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTK---ICKPVL
120 130 140 150 160 170
60 70 80 90 100
pF1KE6 REGEECHPGSHKIPFFRKRKHHTCPCLPNLLC-SRFPDGRYRCSMDLKNINF
::. : .:: . . : : :.::: :.. ..:
XP_016 LEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
180 190 200 210 220
>>NP_055236 (OMIM: 605415) dickkopf-related protein 2 pr (259 aa)
initn: 62 init1: 37 opt: 148 Z-score: 187.1 bits: 40.9 E(85289): 0.0011
Smith-Waterman score: 148; 31.5% identity (54.8% similar) in 73 aa overlap (26-94:183-247)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGR
: :. .: : ::: .: ..: :. .
NP_055 GHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFW---TKICKPVLH
160 170 180 190 200
60 70 80 90 100
pF1KE6 EGEEC----HPGSHKIPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
.:: : . ::: . .:.. : : .: :. . :. :
NP_055 QGEVCTKQRKKGSHGLEIFQR-----CDCAKGLSCKVWKDATYSSKARLHVCQKI
210 220 230 240 250
>>XP_016873044 (OMIM: 605416) PREDICTED: dickkopf-relate (364 aa)
initn: 157 init1: 70 opt: 148 Z-score: 185.0 bits: 41.0 E(85289): 0.0014
Smith-Waterman score: 148; 37.3% identity (58.7% similar) in 75 aa overlap (26-90:208-279)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLR--MCTPL
:. . .: : :::.. ::: .::::
XP_016 CTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQ---RGLLFPVCTPL
180 190 200 210 220 230
60 70 80 90 100
pF1KE6 GREGEECH-PGSHKIPFFRKRKH-----HTCPCLPNLLCS--RFPDGRYRCSMDLKNINF
::: :: :.:. . .. . . ::: .:::. :.:
XP_016 PVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHRLPRLEPGFVPSLPSHSL
240 250 260 270 280 290
XP_016 VYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMALREPAAA
300 310 320 330 340 350
>>NP_001317149 (OMIM: 605416) dickkopf-related protein 3 (364 aa)
initn: 157 init1: 70 opt: 148 Z-score: 185.0 bits: 41.0 E(85289): 0.0014
Smith-Waterman score: 148; 37.3% identity (58.7% similar) in 75 aa overlap (26-90:208-279)
10 20 30 40 50
pF1KE6 MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLR--MCTPL
:. . .: : :::.. ::: .::::
NP_001 CTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQ---RGLLFPVCTPL
180 190 200 210 220 230
60 70 80 90 100
pF1KE6 GREGEECH-PGSHKIPFFRKRKH-----HTCPCLPNLLCS--RFPDGRYRCSMDLKNINF
::: :: :.:. . .. . . ::: .:::. :.:
NP_001 PVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHRLPRLEPGFVPSLPSHSL
240 250 260 270 280 290
NP_001 VYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMALREPAAA
300 310 320 330 340 350
105 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:40:41 2016 done: Tue Nov 8 09:40:42 2016
Total Scan time: 3.240 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]