Result of FASTA (omim) for
pFN21AE6125
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6125, 176 aa
1>>>pF1KE6125 176 - 176 aa - 176 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0496+/-0.000322; mu= 13.3702+/- 0.020
mean_var=58.9660+/-12.359, 0's: 0 Z-trim(115.8): 9 B-trim: 0 in 0/52
Lambda= 0.167022
statistics sampled from 26527 (26536) to 26527 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.311), width: 16
Scan time: 4.240
The best scores are: opt bits E(85289)
NP_002428 (OMIM: 137960,256810) protein Mpv17 [Hom ( 176) 1222 302.4 2.5e-82
XP_005264383 (OMIM: 137960,256810) PREDICTED: prot ( 176) 1222 302.4 2.5e-82
XP_016859639 (OMIM: 137960,256810) PREDICTED: prot ( 170) 1075 266.9 1.1e-71
XP_006712084 (OMIM: 137960,256810) PREDICTED: prot ( 160) 1055 262.1 3e-70
XP_016859640 (OMIM: 137960,256810) PREDICTED: prot ( 160) 1055 262.1 3e-70
XP_016859641 (OMIM: 137960,256810) PREDICTED: prot ( 123) 870 217.5 6.3e-57
NP_116072 (OMIM: 616133) mpv17-like protein 2 prec ( 206) 265 71.8 7.5e-13
>>NP_002428 (OMIM: 137960,256810) protein Mpv17 [Homo sa (176 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1599.1 bits: 302.4 E(85289): 2.5e-82
Smith-Waterman score: 1222; 100.0% identity (100.0% similar) in 176 aa overlap (1-176:1-176)
10 20 30 40 50 60
pF1KE6 MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
130 140 150 160 170
>>XP_005264383 (OMIM: 137960,256810) PREDICTED: protein (176 aa)
initn: 1222 init1: 1222 opt: 1222 Z-score: 1599.1 bits: 302.4 E(85289): 2.5e-82
Smith-Waterman score: 1222; 100.0% identity (100.0% similar) in 176 aa overlap (1-176:1-176)
10 20 30 40 50 60
pF1KE6 MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
130 140 150 160 170
>>XP_016859639 (OMIM: 137960,256810) PREDICTED: protein (170 aa)
initn: 1082 init1: 1063 opt: 1075 Z-score: 1407.9 bits: 266.9 E(85289): 1.1e-71
Smith-Waterman score: 1075; 92.9% identity (94.1% similar) in 170 aa overlap (11-176:1-170)
10 20 30 40 50
pF1KE6 MALWRAYQRALAAHPWKVQ----VLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVS
.:::: . : :::::::::::::::::::::::::::::::::
XP_016 MAAHPRRCPDNTCVPCIGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LGCGFVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCGFVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QDNWAKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDNWAKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
120 130 140 150 160 170
>>XP_006712084 (OMIM: 137960,256810) PREDICTED: protein (160 aa)
initn: 1055 init1: 1055 opt: 1055 Z-score: 1382.2 bits: 262.1 E(85289): 3e-70
Smith-Waterman score: 1055; 100.0% identity (100.0% similar) in 152 aa overlap (25-176:9-160)
10 20 30 40 50 60
pF1KE6 MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
::::::::::::::::::::::::::::::::::::
XP_006 MKLKSHKRSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
10 20 30 40
70 80 90 100 110 120
pF1KE6 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
50 60 70 80 90 100
130 140 150 160 170
pF1KE6 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
110 120 130 140 150 160
>>XP_016859640 (OMIM: 137960,256810) PREDICTED: protein (160 aa)
initn: 1055 init1: 1055 opt: 1055 Z-score: 1382.2 bits: 262.1 E(85289): 3e-70
Smith-Waterman score: 1055; 100.0% identity (100.0% similar) in 152 aa overlap (25-176:9-160)
10 20 30 40 50 60
pF1KE6 MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
::::::::::::::::::::::::::::::::::::
XP_016 MKLKSHKRSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
10 20 30 40
70 80 90 100 110 120
pF1KE6 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
50 60 70 80 90 100
130 140 150 160 170
pF1KE6 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
110 120 130 140 150 160
>>XP_016859641 (OMIM: 137960,256810) PREDICTED: protein (123 aa)
initn: 870 init1: 870 opt: 870 Z-score: 1143.0 bits: 217.5 E(85289): 6.3e-57
Smith-Waterman score: 870; 100.0% identity (100.0% similar) in 123 aa overlap (54-176:1-123)
30 40 50 60 70 80
pF1KE6 GSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCGFVGPVVGGWYKVLDRFIPGTTKV
::::::::::::::::::::::::::::::
XP_016 MVSLGCGFVGPVVGGWYKVLDRFIPGTTKV
10 20 30
90 100 110 120 130 140
pF1KE6 DALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAKLQRDYPDALITNYYLWPAVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAKLQRDYPDALITNYYLWPAVQL
40 50 60 70 80 90
150 160 170
pF1KE6 ANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
:::::::::::::::::::::::::::::::::
XP_016 ANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
100 110 120
>>NP_116072 (OMIM: 616133) mpv17-like protein 2 precurso (206 aa)
initn: 234 init1: 160 opt: 265 Z-score: 351.8 bits: 71.8 E(85289): 7.5e-13
Smith-Waterman score: 273; 29.7% identity (62.2% similar) in 185 aa overlap (4-175:6-188)
10 20 30 40
pF1KE6 MALWRAYQRALAAHPWKVQ--------VLTAGSLMGLGDIISQQL-VERRGLQEHQRG
:: .: :.: : .: :.::. :: . :. .. : : .
NP_116 MARGGWRRLRRLLSAGQLLFQGRALLVTNTLGCGALMAAGDGVRQSWEIRARPGQVFDPR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 RTLTMVSLGCGFVGPVVGGWYKVLDRFIPGTTKV---DALKKMLLDQGGFAPCFLGCFLP
:. .: ..::. .:: . :: :::..:.. ..:::.:.:: .: .:: .
NP_116 RSASMFAVGCS-MGPFLHYWYLSLDRLFPASGLRGFPNVLKKVLVDQLVASP-LLGVWYF
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 L-VGALNGLSAQDNWAKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIW
: .: :.: .. .. .:.. . . ... .:::.:..:: .:: ..:.. .. ... :
NP_116 LGLGCLEGQTVGESCQELREKFWEFYKADWCVWPAAQFVNFLFVPPQFRVTYINGLTLGW
120 130 140 150 160 170
170
pF1KE6 NSYLSWKAHRL
..:::. .:
NP_116 DTYLSYLKYRSPVPLTPPGCVALDTRAD
180 190 200
176 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:40:08 2016 done: Tue Nov 8 09:40:09 2016
Total Scan time: 4.240 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]