Result of FASTA (omim) for
pFN21AE6121
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6121, 135 aa
1>>>pF1KE6121 135 - 135 aa - 135 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8352+/-0.000362; mu= 13.1941+/- 0.022
mean_var=53.5908+/-10.854, 0's: 0 Z-trim(113.5): 28 B-trim: 473 in 1/49
Lambda= 0.175198
statistics sampled from 22852 (22880) to 22852 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.268), width: 16
Scan time: 3.410
The best scores are: opt bits E(85289)
NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 915 238.8 2e-63
XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 746 196.1 1.4e-50
NP_001316383 (OMIM: 611866) retinol-binding protei ( 86) 592 157.1 5.1e-39
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 548 146.1 2.3e-35
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 485 130.1 1e-30
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 460 123.8 8.2e-29
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 346 95.0 4.3e-20
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 345 94.8 5.3e-20
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 320 88.4 3.8e-18
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 320 88.4 3.8e-18
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 320 88.4 3.8e-18
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 297 82.6 2.1e-16
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 270 75.8 2.3e-14
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 265 74.5 5.6e-14
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 249 70.5 8.8e-13
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 238 67.7 6.3e-12
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 229 65.5 3.7e-11
NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 220 63.2 1.5e-10
NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 219 62.9 1.8e-10
NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 209 60.4 1.1e-09
NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 198 57.6 6.8e-09
NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 190 55.5 2.2e-08
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 132 40.9 0.00073
>>NP_113679 (OMIM: 611866) retinol-binding protein 5 iso (135 aa)
initn: 915 init1: 915 opt: 915 Z-score: 1259.7 bits: 238.8 E(85289): 2e-63
Smith-Waterman score: 915; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:1-135)
10 20 30 40 50 60
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
70 80 90 100 110 120
130
pF1KE6 TARDAVCEQVFRKVR
:::::::::::::::
NP_113 TARDAVCEQVFRKVR
130
>>XP_016875491 (OMIM: 611866) PREDICTED: retinol-binding (126 aa)
initn: 746 init1: 746 opt: 746 Z-score: 1029.3 bits: 196.1 E(85289): 1.4e-50
Smith-Waterman score: 746; 99.1% identity (100.0% similar) in 111 aa overlap (25-135:16-126)
10 20 30 40 50 60
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
.:::::::::::::::::::::::::::::::::::
XP_016 MMNQAQWILKPGTMADISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
60 70 80 90 100 110
130
pF1KE6 TARDAVCEQVFRKVR
:::::::::::::::
XP_016 TARDAVCEQVFRKVR
120
>>NP_001316383 (OMIM: 611866) retinol-binding protein 5 (86 aa)
initn: 592 init1: 592 opt: 592 Z-score: 821.5 bits: 157.1 E(85289): 5.1e-39
Smith-Waterman score: 592; 100.0% identity (100.0% similar) in 86 aa overlap (50-135:1-86)
20 30 40 50 60 70
pF1KE6 YLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRNYTVQFDVGVEFEEDLRSVD
::::::::::::::::::::::::::::::
NP_001 MTVRTLSTFRNYTVQFDVGVEFEEDLRSVD
10 20 30
80 90 100 110 120 130
pF1KE6 GRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
40 50 60 70 80
>>NP_002890 (OMIM: 180260) retinol-binding protein 1 iso (197 aa)
initn: 587 init1: 548 opt: 548 Z-score: 755.9 bits: 146.1 E(85289): 2.3e-35
Smith-Waterman score: 548; 55.6% identity (86.7% similar) in 135 aa overlap (1-135:63-197)
10 20 30
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAV
:: ..:::.... ..:.:.::.::....:.
NP_002 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE6 RKIALLLKPDKEIEHQGNHMTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWE
:::: :::::::: ..:.:: .::::::::: ..:.:: :::::: ..: :::.: :.:.
NP_002 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
100 110 120 130 140 150
100 110 120 130
pF1KE6 EEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
..: :::::: .::: .:.::. :.::. .. .::.:::.::.
NP_002 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
160 170 180 190
>>NP_443192 (OMIM: 608604) retinoid-binding protein 7 [H (134 aa)
initn: 498 init1: 485 opt: 485 Z-score: 672.4 bits: 130.1 E(85289): 1e-30
Smith-Waterman score: 485; 49.6% identity (82.7% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
:: .:.: . ..:. :.: :. ::.:..:.:::: ::::.: ::..:. .:..: :..::
NP_443 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
: :.: :: ::.:: :..:.:::...: :....:.:.:::: :::: ::.::. :.::.
NP_443 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
70 80 90 100 110 120
130
pF1KE6 TARDAVCEQVFRKVR
. ::.:.:..
NP_443 FCEGQVCKQTFQRA
130
>>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa)
initn: 437 init1: 421 opt: 460 Z-score: 638.3 bits: 123.8 E(85289): 8.2e-29
Smith-Waterman score: 460; 51.1% identity (80.5% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
: . .: ... :..:.: :..::.:..:.::::. : : :...:... ..: :::::
NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
: :.: :::::.: .:.:.:. ...:::: . :::::::: ::::..:.::. :::::
NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
70 80 90 100 110 120
130
pF1KE6 TARDAVCEQVFRKVR
: : ::.:::.:
NP_004 TCGDQVCRQVFKKK
130
>>NP_001124465 (OMIM: 180260) retinol-binding protein 1 (153 aa)
initn: 371 init1: 346 opt: 346 Z-score: 481.7 bits: 95.0 E(85289): 4.3e-20
Smith-Waterman score: 346; 57.6% identity (89.4% similar) in 85 aa overlap (1-85:63-147)
10 20 30
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAV
:: ..:::.... ..:.:.::.::....:.
NP_001 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE6 RKIALLLKPDKEIEHQGNHMTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWE
:::: :::::::: ..:.:: .::::::::: ..:.:: :::::: ..: :::..
NP_001 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMSETGFS
100 110 120 130 140 150
100 110 120 130
pF1KE6 EEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
NP_001 S
>>NP_001124464 (OMIM: 180260) retinol-binding protein 1 (157 aa)
initn: 370 init1: 345 opt: 345 Z-score: 480.1 bits: 94.8 E(85289): 5.3e-20
Smith-Waterman score: 345; 57.5% identity (88.5% similar) in 87 aa overlap (1-87:63-149)
10 20 30
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAV
:: ..:::.... ..:.:.::.::....:.
NP_001 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE6 RKIALLLKPDKEIEHQGNHMTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWE
:::: :::::::: ..:.:: .::::::::: ..:.:: :::::: ..: :::.. :
NP_001 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMAGVQSR
100 110 120 130 140 150
100 110 120 130
pF1KE6 EEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
NP_001 DLSSL
>>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa)
initn: 306 init1: 165 opt: 320 Z-score: 446.8 bits: 88.4 E(85289): 3.8e-18
Smith-Waterman score: 320; 38.7% identity (72.3% similar) in 137 aa overlap (3-131:2-135)
10 20 30 40 50
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLL--KPDKEIEHQGNHMTVRTLSTF
::..: .... ..:.:. :..:.... .::::. :: ::...:. . ..: .:
NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 RNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEH-LVCVQK---GEVPNRGWRHWL--E
:. ..: :: :::: ..:::: :...: :: :. .:: :: :: :. .: . : .
NP_001 RTTEINFKVGEEFEE--QTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KE6 GEMLYLELTARDAVCEQVFRKVR
::.. : .:: :.:: .:.
NP_001 GELI-LTMTADDVVCTRVYVRE
120 130
>>XP_016855832 (OMIM: 180231) PREDICTED: cellular retino (138 aa)
initn: 306 init1: 165 opt: 320 Z-score: 446.8 bits: 88.4 E(85289): 3.8e-18
Smith-Waterman score: 320; 38.7% identity (72.3% similar) in 137 aa overlap (3-131:2-135)
10 20 30 40 50
pF1KE6 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLL--KPDKEIEHQGNHMTVRTLSTF
::..: .... ..:.:. :..:.... .::::. :: ::...:. . ..: .:
XP_016 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 RNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEH-LVCVQK---GEVPNRGWRHWL--E
:. ..: :: :::: ..:::: :...: :: :. .:: :: :: :. .: . : .
XP_016 RTTEINFKVGEEFEE--QTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KE6 GEMLYLELTARDAVCEQVFRKVR
::.. : .:: :.:: .:.
XP_016 GELI-LTMTADDVVCTRVYVRE
120 130
135 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:38:03 2016 done: Tue Nov 8 09:38:04 2016
Total Scan time: 3.410 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]