Result of FASTA (omim) for
pFN21AE6113
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6113, 134 aa
1>>>pF1KE6113 134 - 134 aa - 134 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6417+/-0.000301; mu= 15.1823+/- 0.019
mean_var=60.2933+/-12.407, 0's: 0 Z-trim(117.5): 34 B-trim: 1034 in 1/52
Lambda= 0.165173
statistics sampled from 29496 (29530) to 29496 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.346), width: 16
Scan time: 4.540
The best scores are: opt bits E(85289)
NP_683725 (OMIM: 250790,613218) cytochrome b5 isof ( 134) 897 221.2 3.9e-58
NP_001905 (OMIM: 250790,613218) cytochrome b5 isof ( 98) 656 163.7 6e-41
XP_011524137 (OMIM: 250790,613218) PREDICTED: cyto ( 98) 656 163.7 6e-41
NP_001177736 (OMIM: 250790,613218) cytochrome b5 i ( 124) 575 144.5 4.6e-35
NP_085056 (OMIM: 611964) cytochrome b5 type B [Hom ( 150) 457 116.4 1.6e-26
NP_004256 (OMIM: 606149) fatty acid desaturase 2 i ( 444) 210 57.9 1.9e-08
NP_037534 (OMIM: 606148) fatty acid desaturase 1 [ ( 501) 183 51.5 1.8e-06
XP_011521619 (OMIM: 611026,612319) PREDICTED: fatt ( 369) 180 50.7 2.3e-06
NP_077282 (OMIM: 611026,612319) fatty acid 2-hydro ( 372) 180 50.7 2.3e-06
NP_057314 (OMIM: 608343) cytochrome b5 reductase 4 ( 521) 181 51.0 2.6e-06
NP_068373 (OMIM: 606150) fatty acid desaturase 3 [ ( 445) 178 50.3 3.7e-06
XP_011543325 (OMIM: 606150) PREDICTED: fatty acid ( 454) 178 50.3 3.8e-06
NP_001027558 (OMIM: 272300,606887) sulfite oxidase ( 545) 175 49.6 7.1e-06
NP_000447 (OMIM: 272300,606887) sulfite oxidase, m ( 545) 175 49.6 7.1e-06
XP_016875396 (OMIM: 272300,606887) PREDICTED: sulf ( 545) 175 49.6 7.1e-06
NP_001027559 (OMIM: 272300,606887) sulfite oxidase ( 545) 175 49.6 7.1e-06
XP_016875397 (OMIM: 272300,606887) PREDICTED: sulf ( 545) 175 49.6 7.1e-06
XP_016875394 (OMIM: 272300,606887) PREDICTED: sulf ( 552) 175 49.6 7.2e-06
XP_016875395 (OMIM: 272300,606887) PREDICTED: sulf ( 552) 175 49.6 7.2e-06
XP_005269169 (OMIM: 272300,606887) PREDICTED: sulf ( 552) 175 49.6 7.2e-06
XP_011520435 (OMIM: 176270,227220,605837,615516) P (3749) 143 42.7 0.0062
XP_011520433 (OMIM: 176270,227220,605837,615516) P (4673) 143 42.7 0.0073
XP_006720790 (OMIM: 176270,227220,605837,615516) P (4748) 143 42.7 0.0074
XP_016878185 (OMIM: 176270,227220,605837,615516) P (4796) 143 42.7 0.0075
XP_016878184 (OMIM: 176270,227220,605837,615516) P (4796) 143 42.7 0.0075
XP_005268333 (OMIM: 176270,227220,605837,615516) P (4796) 143 42.7 0.0075
XP_006720789 (OMIM: 176270,227220,605837,615516) P (4829) 143 42.7 0.0075
NP_004658 (OMIM: 176270,227220,605837,615516) E3 u (4834) 143 42.7 0.0075
>>NP_683725 (OMIM: 250790,613218) cytochrome b5 isoform (134 aa)
initn: 897 init1: 897 opt: 897 Z-score: 1164.6 bits: 221.2 E(85289): 3.9e-58
Smith-Waterman score: 897; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134)
10 20 30 40 50 60
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISA
70 80 90 100 110 120
130
pF1KE6 VAVALMYRLYMAED
::::::::::::::
NP_683 VAVALMYRLYMAED
130
>>NP_001905 (OMIM: 250790,613218) cytochrome b5 isoform (98 aa)
initn: 656 init1: 656 opt: 656 Z-score: 856.1 bits: 163.7 E(85289): 6e-41
Smith-Waterman score: 656; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)
10 20 30 40 50 60
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISA
:::::::::::::::::::::::::::::::::::::
NP_001 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP
70 80 90
130
pF1KE6 VAVALMYRLYMAED
>>XP_011524137 (OMIM: 250790,613218) PREDICTED: cytochro (98 aa)
initn: 656 init1: 656 opt: 656 Z-score: 856.1 bits: 163.7 E(85289): 6e-41
Smith-Waterman score: 656; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)
10 20 30 40 50 60
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISA
:::::::::::::::::::::::::::::::::::::
XP_011 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP
70 80 90
130
pF1KE6 VAVALMYRLYMAED
>>NP_001177736 (OMIM: 250790,613218) cytochrome b5 isofo (124 aa)
initn: 575 init1: 575 opt: 575 Z-score: 750.4 bits: 144.5 E(85289): 4.6e-35
Smith-Waterman score: 790; 92.5% identity (92.5% similar) in 134 aa overlap (1-134:1-124)
10 20 30 40 50 60
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISA
:::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 ENFEDVGHSTDAREMSKTFIIGELHP----------ETLITTIDSSSSWWTNWVIPAISA
70 80 90 100 110
130
pF1KE6 VAVALMYRLYMAED
::::::::::::::
NP_001 VAVALMYRLYMAED
120
>>NP_085056 (OMIM: 611964) cytochrome b5 type B [Homo sa (150 aa)
initn: 395 init1: 368 opt: 457 Z-score: 597.3 bits: 116.4 E(85289): 1.6e-26
Smith-Waterman score: 457; 50.4% identity (75.9% similar) in 133 aa overlap (3-133:18-146)
10 20 30 40
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHP
.. . .: :: :::. :.: : ::..: .:::.:.::.:::
NP_085 MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 GGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDD-RPKL-NKPPETLITTI
:::::: :::: ::.:.:::::::.::::: : . ::..::.: .:. .: : .
NP_085 GGEEVLLEQAGVDASESFEDVGHSSDAREMLKQYYIGDIHPSDLKPESGSKDP----SKN
70 80 90 100 110
110 120 130
pF1KE6 DSSSSWWTNWVIPAISAVAVALMYRLYMAED
:. .: :. :..: :.:: ....:: : .:
NP_085 DTCKSCWAYWILPIIGAVLLGFLYRYYTSESKSS
120 130 140 150
>>NP_004256 (OMIM: 606149) fatty acid desaturase 2 isofo (444 aa)
initn: 224 init1: 185 opt: 210 Z-score: 272.7 bits: 57.9 E(85289): 1.9e-08
Smith-Waterman score: 210; 35.6% identity (68.3% similar) in 101 aa overlap (2-101:11-110)
10 20 30 40 50
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVL
: . . .: .. ::::::: . ::.. .:::..::. .::::..:.
NP_004 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 REQAGGDATENFEDVGHSTD-AREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWW
. :: :::. :. . . . .. : ..:::: :.. :. .. .. ::
NP_004 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEE-PSQDHGKNSKITEDFRALRKT
70 80 90 100 110
120 130
pF1KE6 TNWVIPAISAVAVALMYRLYMAED
NP_004 AEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQ
120 130 140 150 160 170
>>NP_037534 (OMIM: 606148) fatty acid desaturase 1 [Homo (501 aa)
initn: 178 init1: 135 opt: 183 Z-score: 237.2 bits: 51.5 E(85289): 1.8e-06
Smith-Waterman score: 183; 31.5% identity (68.5% similar) in 89 aa overlap (10-94:75-163)
10 20 30
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTK
.:.: .:. ... . ::.. .:::....
NP_037 APAGPARGVARPAMAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISE
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE6 FLEEHPGGEEVLREQAGGDATENFEDVGHSTD-AREMSKTFIIGELHPDD---RPKLNKP
: ..:::: .:. . :: :::. : . .... ....:::: :.. .: ::
NP_037 FTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKE
110 120 130 140 150 160
100 110 120 130
pF1KE6 PETLITTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED
NP_037 LTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLL
170 180 190 200 210 220
>>XP_011521619 (OMIM: 611026,612319) PREDICTED: fatty ac (369 aa)
initn: 191 init1: 113 opt: 180 Z-score: 235.2 bits: 50.7 E(85289): 2.3e-06
Smith-Waterman score: 180; 28.9% identity (70.0% similar) in 90 aa overlap (12-99:11-100)
10 20 30 40 50 60
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
.. :.:.. . . :. ..:::..:...:::::..:: .:: : .
XP_011 MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDIS
10 20 30 40 50
70 80 90 100 110
pF1KE6 ENFEDVGH--STDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAI
... : :..::. . . .:::. ... .... : .:
XP_011 ADLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDW
60 70 80 90 100 110
120 130
pF1KE6 SAVAVALMYRLYMAED
XP_011 DKDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPL
120 130 140 150 160 170
>>NP_077282 (OMIM: 611026,612319) fatty acid 2-hydroxyla (372 aa)
initn: 163 init1: 113 opt: 180 Z-score: 235.1 bits: 50.7 E(85289): 2.3e-06
Smith-Waterman score: 180; 28.9% identity (70.0% similar) in 90 aa overlap (12-99:11-100)
10 20 30 40 50 60
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT
.. :.:.. . . :. ..:::..:...:::::..:: .:: : .
NP_077 MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDIS
10 20 30 40 50
70 80 90 100 110
pF1KE6 ENFEDVGH--STDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAI
... : :..::. . . .:::. ... .... : .:
NP_077 ADLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDW
60 70 80 90 100 110
120 130
pF1KE6 SAVAVALMYRLYMAED
NP_077 DKDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPL
120 130 140 150 160 170
>>NP_057314 (OMIM: 608343) cytochrome b5 reductase 4 [Ho (521 aa)
initn: 162 init1: 162 opt: 181 Z-score: 234.4 bits: 51.0 E(85289): 2.6e-06
Smith-Waterman score: 181; 36.1% identity (73.6% similar) in 72 aa overlap (13-84:58-129)
10 20 30 40
pF1KE6 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLE
: ::..:::.. . :. .. ::... ..:
NP_057 LKQGRSLMDWIRLTKSGKDLTGLKGRLIEVTEEELKKHNKKDDCWICIRGFVYNVSPYME
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE6 EHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITT
:::::. : . ::.:.:: :..: . .. . : : ..:..
NP_057 YHPGGEDELMRAAGSDGTELFDQVHRWVNYESMLKECLVGRMAIKPAVLKDYREEEKKVL
90 100 110 120 130 140
110 120 130
pF1KE6 IDSSSSWWTNWVIPAISAVAVALMYRLYMAED
NP_057 NGMLPKSQVTDTLAKEGPSYPSYDWFQTDSLVTIAIYTKQKDINLDSIIVDHQNDSFRAE
150 160 170 180 190 200
134 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:33:45 2016 done: Tue Nov 8 09:33:46 2016
Total Scan time: 4.540 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]