Result of FASTA (omim) for
pFN21AE6112
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6112, 135 aa
1>>>pF1KE6112 135 - 135 aa - 135 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9140+/-0.000369; mu= 12.7482+/- 0.023
mean_var=55.4814+/-11.361, 0's: 0 Z-trim(112.1): 34 B-trim: 1021 in 2/50
Lambda= 0.172187
statistics sampled from 20810 (20844) to 20810 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.244), width: 16
Scan time: 2.600
The best scores are: opt bits E(85289)
NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 896 230.4 6.6e-61
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 499 131.8 3.2e-31
NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 468 124.1 6.6e-29
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 438 116.7 1.2e-26
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 398 106.7 1.1e-23
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 397 106.5 1.3e-23
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 371 100.1 1.4e-21
NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 339 92.1 3.1e-19
NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 321 87.6 6.3e-18
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 280 77.4 7.8e-15
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 280 77.4 7.8e-15
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 280 77.4 7.8e-15
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 277 76.7 1.3e-14
NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 262 72.9 1.3e-13
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 234 66.1 2.9e-11
NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 220 62.5 2.4e-10
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 205 58.8 3.1e-09
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 193 55.8 2.7e-08
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 186 54.1 9.3e-08
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 184 53.6 1.1e-07
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 184 53.6 1.2e-07
XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 167 49.3 2e-06
>>NP_001435 (OMIM: 605168) fatty acid-binding protein, e (135 aa)
initn: 896 init1: 896 opt: 896 Z-score: 1214.4 bits: 230.4 E(85289): 6.6e-61
Smith-Waterman score: 896; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:1-135)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
70 80 90 100 110 120
130
pF1KE6 VMNNVTCTRIYEKVE
:::::::::::::::
NP_001 VMNNVTCTRIYEKVE
130
>>NP_002668 (OMIM: 170715) myelin P2 protein [Homo sapie (132 aa)
initn: 499 init1: 499 opt: 499 Z-score: 681.6 bits: 131.8 E(85289): 3.2e-31
Smith-Waterman score: 499; 58.7% identity (84.1% similar) in 126 aa overlap (9-134:7-132)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
: :.::.:..::.::: ::::.: ::.: .::: ::. : .::.::::.
NP_002 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: ::..:::::::.:::... .. :.: : :.:::::.:: ::: .::.:.::
NP_002 KNTEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAEC
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
:..:.::::::::
NP_002 KMKGVVCTRIYEKV
120 130
>>NP_001433 (OMIM: 600434) fatty acid-binding protein, a (132 aa)
initn: 467 init1: 443 opt: 468 Z-score: 640.0 bits: 124.1 E(85289): 6.6e-29
Smith-Waterman score: 468; 55.2% identity (85.6% similar) in 125 aa overlap (9-133:7-131)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
: :.::.:..::.::::.:::.: ::...::::. ::. .: .:::.:::.
NP_001 MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: ::..:.:.::: ::.... .. :.::. :.:::: .:: :: .: ::::::
NP_001 KNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVEC
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
::..:: ::.::.
NP_001 VMKGVTSTRVYERA
120 130
>>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa)
initn: 438 init1: 438 opt: 438 Z-score: 599.6 bits: 116.7 E(85289): 1.2e-26
Smith-Waterman score: 438; 50.0% identity (80.8% similar) in 130 aa overlap (4-133:2-131)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
:. . : :.:::::.::.::: ::::.: :....:.:: :: .: ::.::.::.
NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: :: .:.::::: ::.... .. : ::. :.:::.:.:..:.: ::::..
NP_004 KNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTL
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
. ....::: :::
NP_004 THGTAVCTRTYEKEA
120 130
>>XP_011539309 (OMIM: 134651) PREDICTED: fatty acid-bind (126 aa)
initn: 403 init1: 371 opt: 398 Z-score: 546.3 bits: 106.7 E(85289): 1.1e-23
Smith-Waterman score: 398; 51.3% identity (81.7% similar) in 115 aa overlap (4-118:2-116)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
:. . : :.:::::.::.::: ::::.: :....:.:: :: .: ::.::.::.
XP_011 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: :: .:.::::: ::.... .. : ::. :.:::.:.:..:.: ::::..
XP_011 KNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILME
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
XP_011 KLQLRNVK
120
>>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa)
initn: 397 init1: 397 opt: 397 Z-score: 544.6 bits: 106.5 E(85289): 1.3e-23
Smith-Waterman score: 397; 45.4% identity (80.8% similar) in 130 aa overlap (4-133:2-131)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
:. . . :.:..:..:::::: ::::.: :..: ..:: ::. .: ...:.: ::.
NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: :::.:.::::: :. ..: .. ::. :.:::::....:..::::.:.
NP_001 KNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTL
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
....:. .: :::
NP_001 TFGDVVAVRHYEKA
120 130
>>NP_001305968 (OMIM: 602965) fatty acid-binding protein (166 aa)
initn: 368 init1: 336 opt: 371 Z-score: 508.2 bits: 100.1 E(85289): 1.4e-21
Smith-Waterman score: 371; 47.0% identity (81.7% similar) in 115 aa overlap (4-118:2-116)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
:. . . :.:..:..:::::: ::::.: :..: ..:: ::. .: ...:.: ::.
NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: :::.:.::::: :. ..: .. ::. :.:::::....:..::::.:.
NP_001 KNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMVS
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
NP_001 NDNSPFFLVFFSSPHTSHLLPSSSLLLPFFLLPSFFNNTSLARFFNYM
120 130 140 150 160
>>NP_001307925 (OMIM: 134651) fatty acid-binding protein (144 aa)
initn: 424 init1: 339 opt: 339 Z-score: 466.2 bits: 92.1 E(85289): 3.1e-19
Smith-Waterman score: 406; 46.1% identity (74.5% similar) in 141 aa overlap (4-133:2-142)
10 20 30 40
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKEL-----------GVGIALRKMGAMAKPDCIITCDG
:. . : :.:::::.::.::: : :::.: :....:.:: :: .:
NP_001 MVDAFLGTWKLVDSKNFDDYMKSLAHILITFPLPSGVGFATRQVASMTKPTTIIEKNG
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 KNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITR
::.::.::.:.:..: :: .:.::::: ::.... .. : ::. :.:::.:.:..:
NP_001 DILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVR
60 70 80 90 100 110
110 120 130
pF1KE6 KLKDGKLVVECVMNNVTCTRIYEKVE
.: ::::.. . ....::: :::
NP_001 ELIDGKLILTLTHGTAVCTRTYEKEA
120 130 140
>>NP_001305971 (OMIM: 602965) fatty acid-binding protein (128 aa)
initn: 316 init1: 316 opt: 321 Z-score: 442.8 bits: 87.6 E(85289): 6.3e-18
Smith-Waterman score: 321; 40.8% identity (73.1% similar) in 130 aa overlap (4-133:1-127)
10 20 30 40 50 60
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
.: : :: : . .. :::.: :..: ..:: ::. .: ...:.: ::.
NP_001 MQLKEKDWR---SALIKTANQQKGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
:.:..: :::.:.::::: :. ..: .. ::. :.:::::....:..::::.:.
NP_001 KNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTL
60 70 80 90 100 110
130
pF1KE6 VMNNVTCTRIYEKVE
....:. .: :::
NP_001 TFGDVVAVRHYEKA
120
>>NP_001186652 (OMIM: 180231) cellular retinoic acid-bin (138 aa)
initn: 206 init1: 120 opt: 280 Z-score: 387.3 bits: 77.4 E(85289): 7.8e-15
Smith-Waterman score: 280; 35.4% identity (73.1% similar) in 130 aa overlap (9-131:6-135)
10 20 30 40 50
pF1KE6 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMG--AMAKPDCIITCDGKNLTIKTES
: :... :..:.: .: :::.. :::.. : .:: : .: .. ::: .
NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTST
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 TLKTTQFSCTLGEKFEETTADGRKTQTVCNF-TDGALVQHQEW---DGKESTITRKL-KD
:..::... .::.::: :.::: ... .. ... .: .:. .: ... ::.: .:
NP_001 TVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KE6 GKLVVECVMNNVTCTRIYEKVE
:.:.. . ..:.:::.:
NP_001 GELILTMTADDVVCTRVYVRE
120 130
135 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:32:56 2016 done: Tue Nov 8 09:32:57 2016
Total Scan time: 2.600 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]