Result of FASTA (omim) for
pFN21AE5825
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5825, 1216 aa
1>>>pF1KE5825 1216 - 1216 aa - 1216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6022+/-0.000573; mu= 15.3301+/- 0.035
mean_var=125.0791+/-23.972, 0's: 0 Z-trim(110.1): 418 B-trim: 81 in 2/52
Lambda= 0.114678
statistics sampled from 17860 (18337) to 17860 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.215), width: 16
Scan time: 13.250
The best scores are: opt bits E(85289)
NP_109592 (OMIM: 600579,614196) receptor-type tyro (1216) 8121 1356.8 0
XP_016875214 (OMIM: 600579,614196) PREDICTED: rece ( 974) 5782 969.8 0
NP_002839 (OMIM: 600579,614196) receptor-type tyro (1188) 5782 969.9 0
NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405) 2752 468.2 4.9e-131
NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405) 2752 468.2 4.9e-131
NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377) 2155 369.4 2.5e-101
NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377) 2155 369.4 2.5e-101
XP_016875213 (OMIM: 176882) PREDICTED: receptor-ty (1446) 1003 179.3 1.6e-43
NP_001193901 (OMIM: 176882) receptor-type tyrosine (1907) 1003 179.4 2e-43
NP_001193900 (OMIM: 176882) receptor-type tyrosine (1907) 1003 179.4 2e-43
NP_002828 (OMIM: 176882) receptor-type tyrosine-pr (1997) 1003 179.4 2.1e-43
XP_006719592 (OMIM: 176882) PREDICTED: receptor-ty (2012) 1003 179.4 2.1e-43
NP_001317133 (OMIM: 176882) receptor-type tyrosine (2127) 1003 179.4 2.2e-43
XP_011536916 (OMIM: 176882) PREDICTED: receptor-ty (2142) 1003 179.4 2.2e-43
NP_001103224 (OMIM: 176882) receptor-type tyrosine (2215) 1003 179.4 2.3e-43
XP_006719591 (OMIM: 176882) PREDICTED: receptor-ty (2230) 1003 179.4 2.3e-43
XP_016874762 (OMIM: 603317,613391) PREDICTED: phos (2536) 976 175.0 5.6e-42
NP_001138498 (OMIM: 603317,613391) phosphatidylino (2299) 965 173.1 1.8e-41
XP_016873574 (OMIM: 600925) PREDICTED: receptor-ty (1321) 946 169.8 1.1e-40
NP_002834 (OMIM: 600925) receptor-type tyrosine-pr (1337) 946 169.8 1.1e-40
XP_016873573 (OMIM: 600925) PREDICTED: receptor-ty (1344) 946 169.8 1.1e-40
XP_016873572 (OMIM: 600925) PREDICTED: receptor-ty (1363) 946 169.8 1.1e-40
XP_016882552 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 916 164.7 2.5e-39
XP_011525490 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 916 164.7 2.5e-39
XP_016882551 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 916 164.7 2.5e-39
NP_001154912 (OMIM: 602510) receptor-type tyrosine ( 937) 916 164.7 2.5e-39
XP_016882550 (OMIM: 602510) PREDICTED: receptor-ty ( 959) 916 164.7 2.6e-39
NP_002833 (OMIM: 602510) receptor-type tyrosine-pr (1115) 916 164.8 2.9e-39
XP_011525485 (OMIM: 602510) PREDICTED: receptor-ty (1122) 916 164.8 2.9e-39
XP_016882547 (OMIM: 602510) PREDICTED: receptor-ty (1130) 916 164.8 2.9e-39
XP_016882546 (OMIM: 602510) PREDICTED: receptor-ty (1133) 916 164.8 2.9e-39
XP_016882545 (OMIM: 602510) PREDICTED: receptor-ty (1137) 916 164.8 2.9e-39
XP_016882549 (OMIM: 602510) PREDICTED: receptor-ty (1121) 914 164.4 3.7e-39
XP_016882548 (OMIM: 602510) PREDICTED: receptor-ty (1121) 841 152.4 1.6e-35
NP_001316069 (OMIM: 179590,616001) receptor-type t (1603) 770 140.7 7.1e-32
XP_016857436 (OMIM: 179590,616001) PREDICTED: rece (1618) 770 140.7 7.2e-32
NP_001316068 (OMIM: 179590,616001) receptor-type t (1623) 770 140.7 7.2e-32
XP_016857438 (OMIM: 179590,616001) PREDICTED: rece (1623) 770 140.7 7.2e-32
XP_016857435 (OMIM: 179590,616001) PREDICTED: rece (1627) 770 140.7 7.2e-32
NP_001316066 (OMIM: 179590,616001) receptor-type t (1629) 770 140.7 7.2e-32
NP_001316067 (OMIM: 179590,616001) receptor-type t (1637) 770 140.7 7.3e-32
XP_006710864 (OMIM: 179590,616001) PREDICTED: rece (1729) 770 140.8 7.6e-32
XP_005271139 (OMIM: 179590,616001) PREDICTED: rece (1796) 770 140.8 7.8e-32
XP_016857433 (OMIM: 179590,616001) PREDICTED: rece (1800) 770 140.8 7.8e-32
XP_016857434 (OMIM: 179590,616001) PREDICTED: rece (1807) 770 140.8 7.8e-32
XP_006710863 (OMIM: 179590,616001) PREDICTED: rece (1811) 770 140.8 7.8e-32
XP_016857432 (OMIM: 179590,616001) PREDICTED: rece (1816) 770 140.8 7.8e-32
XP_006710862 (OMIM: 179590,616001) PREDICTED: rece (1820) 770 140.8 7.9e-32
NP_569707 (OMIM: 179590,616001) receptor-type tyro (1898) 770 140.8 8.1e-32
XP_006710861 (OMIM: 179590,616001) PREDICTED: rece (1902) 770 140.8 8.1e-32
>>NP_109592 (OMIM: 600579,614196) receptor-type tyrosine (1216 aa)
initn: 8121 init1: 8121 opt: 8121 Z-score: 7267.7 bits: 1356.8 E(85289): 0
Smith-Waterman score: 8121; 100.0% identity (100.0% similar) in 1216 aa overlap (1-1216:1-1216)
10 20 30 40 50 60
pF1KE5 MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 INPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 INPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE5 LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE5 FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE5 FRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 FRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE5 GRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 GRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK
1150 1160 1170 1180 1190 1200
1210
pF1KE5 QQFCISDVIYENVSKS
::::::::::::::::
NP_109 QQFCISDVIYENVSKS
1210
>>XP_016875214 (OMIM: 600579,614196) PREDICTED: receptor (974 aa)
initn: 5826 init1: 5782 opt: 5782 Z-score: 5177.6 bits: 969.8 E(85289): 0
Smith-Waterman score: 5969; 97.0% identity (97.0% similar) in 943 aa overlap (1-943:1-915)
10 20 30 40 50 60
pF1KE5 MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFY
::::::::::::::::::::::::::::::::::::
XP_016 LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNW------------------------
850 860 870
910 920 930 940 950 960
pF1KE5 INPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
:::::::::::::::::::::::::::::::::::::::
XP_016 ----SKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEPRTALVCKKHQWSWCGD
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE5 LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
XP_016 TNGEFEDEKNLIHYQIQRPLTTTCVLKNSTQSLLTYPLYPGA
940 950 960 970
>>NP_002839 (OMIM: 600579,614196) receptor-type tyrosine (1188 aa)
initn: 5826 init1: 5782 opt: 5782 Z-score: 5176.4 bits: 969.9 E(85289): 0
Smith-Waterman score: 7853; 97.7% identity (97.7% similar) in 1216 aa overlap (1-1216:1-1188)
10 20 30 40 50 60
pF1KE5 MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFY
::::::::::::::::::::::::::::::::::::
NP_002 LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNW------------------------
850 860 870
910 920 930 940 950 960
pF1KE5 INPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ----SKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE5 LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE5 FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE5 FRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGV
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE5 GRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK
1120 1130 1140 1150 1160 1170
1210
pF1KE5 QQFCISDVIYENVSKS
::::::::::::::::
NP_002 QQFCISDVIYENVSKS
1180
>>NP_109594 (OMIM: 600579,614196) receptor-type tyrosine (405 aa)
initn: 2752 init1: 2752 opt: 2752 Z-score: 2473.5 bits: 468.2 E(85289): 4.9e-131
Smith-Waterman score: 2752; 100.0% identity (100.0% similar) in 405 aa overlap (812-1216:1-405)
790 800 810 820 830 840
pF1KE5 SLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTL
::::::::::::::::::::::::::::::
NP_109 MVTEMNPNVVVISVLAILSTLLIGLLLVTL
10 20 30
850 860 870 880 890 900
pF1KE5 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYI
40 50 60 70 80 90
910 920 930 940 950 960
pF1KE5 NPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
100 110 120 130 140 150
970 980 990 1000 1010 1020
pF1KE5 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
160 170 180 190 200 210
1030 1040 1050 1060 1070 1080
pF1KE5 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
220 230 240 250 260 270
1090 1100 1110 1120 1130 1140
pF1KE5 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
280 290 300 310 320 330
1150 1160 1170 1180 1190 1200
pF1KE5 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
340 350 360 370 380 390
1210
pF1KE5 QFCISDVIYENVSKS
:::::::::::::::
NP_109 QFCISDVIYENVSKS
400
>>NP_109596 (OMIM: 600579,614196) receptor-type tyrosine (405 aa)
initn: 2752 init1: 2752 opt: 2752 Z-score: 2473.5 bits: 468.2 E(85289): 4.9e-131
Smith-Waterman score: 2752; 100.0% identity (100.0% similar) in 405 aa overlap (812-1216:1-405)
790 800 810 820 830 840
pF1KE5 SLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTL
::::::::::::::::::::::::::::::
NP_109 MVTEMNPNVVVISVLAILSTLLIGLLLVTL
10 20 30
850 860 870 880 890 900
pF1KE5 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYI
40 50 60 70 80 90
910 920 930 940 950 960
pF1KE5 NPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
100 110 120 130 140 150
970 980 990 1000 1010 1020
pF1KE5 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
160 170 180 190 200 210
1030 1040 1050 1060 1070 1080
pF1KE5 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
220 230 240 250 260 270
1090 1100 1110 1120 1130 1140
pF1KE5 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
280 290 300 310 320 330
1150 1160 1170 1180 1190 1200
pF1KE5 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
340 350 360 370 380 390
1210
pF1KE5 QFCISDVIYENVSKS
:::::::::::::::
NP_109 QFCISDVIYENVSKS
400
>>NP_109595 (OMIM: 600579,614196) receptor-type tyrosine (377 aa)
initn: 2155 init1: 2155 opt: 2155 Z-score: 1940.1 bits: 369.4 E(85289): 2.5e-101
Smith-Waterman score: 2484; 93.1% identity (93.1% similar) in 405 aa overlap (812-1216:1-377)
790 800 810 820 830 840
pF1KE5 SLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTL
::::::::::::::::::::::::::::::
NP_109 MVTEMNPNVVVISVLAILSTLLIGLLLVTL
10 20 30
850 860 870 880 890 900
pF1KE5 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYI
:::::::::::::::::::::::::::::::::::
NP_109 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNW-------------------------
40 50 60
910 920 930 940 950 960
pF1KE5 NPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 ---SKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
70 80 90 100 110 120
970 980 990 1000 1010 1020
pF1KE5 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
130 140 150 160 170 180
1030 1040 1050 1060 1070 1080
pF1KE5 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
190 200 210 220 230 240
1090 1100 1110 1120 1130 1140
pF1KE5 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
250 260 270 280 290 300
1150 1160 1170 1180 1190 1200
pF1KE5 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
310 320 330 340 350 360
1210
pF1KE5 QFCISDVIYENVSKS
:::::::::::::::
NP_109 QFCISDVIYENVSKS
370
>>NP_109593 (OMIM: 600579,614196) receptor-type tyrosine (377 aa)
initn: 2155 init1: 2155 opt: 2155 Z-score: 1940.1 bits: 369.4 E(85289): 2.5e-101
Smith-Waterman score: 2484; 93.1% identity (93.1% similar) in 405 aa overlap (812-1216:1-377)
790 800 810 820 830 840
pF1KE5 SLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTL
::::::::::::::::::::::::::::::
NP_109 MVTEMNPNVVVISVLAILSTLLIGLLLVTL
10 20 30
850 860 870 880 890 900
pF1KE5 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYI
:::::::::::::::::::::::::::::::::::
NP_109 IILRKKHLQMARECGAGTFVNFASLERDGKLPYNW-------------------------
40 50 60
910 920 930 940 950 960
pF1KE5 NPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 ---SKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPL
70 80 90 100 110 120
970 980 990 1000 1010 1020
pF1KE5 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF
130 140 150 160 170 180
1030 1040 1050 1060 1070 1080
pF1KE5 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHF
190 200 210 220 230 240
1090 1100 1110 1120 1130 1140
pF1KE5 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVG
250 260 270 280 290 300
1150 1160 1170 1180 1190 1200
pF1KE5 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 RTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQ
310 320 330 340 350 360
1210
pF1KE5 QFCISDVIYENVSKS
:::::::::::::::
NP_109 QFCISDVIYENVSKS
370
>>XP_016875213 (OMIM: 176882) PREDICTED: receptor-type t (1446 aa)
initn: 947 init1: 571 opt: 1003 Z-score: 902.1 bits: 179.3 E(85289): 1.6e-43
Smith-Waterman score: 1034; 29.8% identity (57.1% similar) in 885 aa overlap (349-1214:625-1419)
320 330 340 350 360 370
pF1KE5 MEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTA-FDGFHIHIEREENFTEYLMV
:. .: .. :: ... . .. .
XP_016 LSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWK
600 610 620 630 640 650
380 390 400 410 420 430
pF1KE5 DEEAHEFVAELKEPG-KYKLSVTTFSSSGSCE-TRKSQSAKSLSFYISPSGEWIEELTEK
:.. :. . :: :: : :.: :.. : . : .:..: : :
XP_016 DKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPS------P-----------
660 670 680 690
440 450 460 470 480 490
pF1KE5 PQHVSVHVLSSTTALMSWTSSQE--NYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSK
:. .: ...:. ..: . . .::. .. . ... . . : .. . ..
XP_016 PSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLP------RDALTVFNPYNNRKSEGR
700 710 720 730 740 750
500 510 520 530 540 550
pF1KE5 PIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIV---PTGIKDLMLYPLGPTAVVLSW
:. .: :: .:: . .: : :. :. : : :..: : . ::.. ::
XP_016 -IVYGLRPGRSYQFNVKTVSGDSWKTYSKPI-FGSVRTKPDKIQNLHCRPQNSTAIACSW
760 770 780 790 800
560 570 580 590 600 610
pF1KE5 TRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTM
: . : : .: .. :. :.. : .. . : :.: : . .
XP_016 IPPD-SDFDGYSIECRKMD--TQEVEFSRKLEKEKSL-----LNIMMLVPHKRYLVSIKV
810 820 830 840 850 860
620 630 640 650 660 670
pF1KE5 VTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMV
. : ..:::..: : : .. .. . :: . . :.. : :.
XP_016 QSAGMTS-EVVEDSTITMIDRP-PPPPPHIRVNEKDVLISKSSINFTVNCS------WFS
870 880 890 900 910
680 690 700 710 720 730
pF1KE5 VAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLF
..: : :.:.. . : : . . : . : :.:. :. . . :
XP_016 DTNGAVKYFTVVVREA-DGSDELKPEQQHPLP--SYLEYRHNASI-RVYQTNYFASKCAE
920 930 940 950 960
740 750 760 770 780
pF1KE5 AVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAV-SSHVVTISSLLPATAY
:... : . .. :. .: . . .:. . :. ... ..: .. . .
XP_016 NPNSNSKSFN---IKLGAE--MESLGGKCDPTQQKFCDGPLKPHTAYRISIRAF--TQLF
970 980 990 1000 1010 1020
790 800 810 820 830 840
pF1KE5 NCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLL--VTLIILRKK
. .. :.. : ::... ..:: .: .: .. . .:::.:. :.:.: :.:
XP_016 DEDLKEFTKPLYS-DTFFSLP-ITTESEPLFGAIEGVSA-GLFLIGMLVAVVALLICRQK
1030 1040 1050 1060 1070
850 860 870 880 890 900
pF1KE5 HLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKN
.. .:: .. . :..:: : . . :.: ...
XP_016 -VSHGRERPSARL----SIRRD--------RPLSVHLNL------------------GQK
1080 1090 1100
910 920 930 940 950 960
pF1KE5 GLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNR
: .:: . :.....:.... . ::.: .: ..:::: .: . : :: :: :::
XP_016 G--NRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNR
1110 1120 1130 1140 1150 1160
970 980 990 1000 1010 1020
pF1KE5 YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
:.:::::: .::.: ..... .:::::.:::: : .:::.:::::: :..:::::: .
XP_016 YNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWE
1170 1180 1190 1200 1210 1220
1030 1040 1050 1060 1070 1080
pF1KE5 QKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI---N
:. . :::.::: :: ::::::::: .. . :::. ..:.:: .:. :.:.: .
XP_016 QNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEE
1230 1240 1250 1260 1270 1280
1090 1100 1110 1120 1130 1140
pF1KE5 YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKG--PMIIHCSAGVGR
: . . ::.::.::::::: ....:..:::. ::. ..: : : ..::::::::
XP_016 QLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGR
1290 1300 1310 1320 1330 1340
1150 1160 1170 1180 1190 1200
pF1KE5 TGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK--
:::::::::.::.. ... ::: : : ..: .:. ::::: ::...::::. . .:
XP_016 TGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
1350 1360 1370 1380 1390 1400
1210
pF1KE5 -QQFCISDVIYENVSKS
.: :::::.
XP_016 SEQENPLFPIYENVNPEYHRGGHLLHLLPQVSSSRYGQSGQA
1410 1420 1430 1440
>>NP_001193901 (OMIM: 176882) receptor-type tyrosine-pro (1907 aa)
initn: 959 init1: 571 opt: 1003 Z-score: 900.5 bits: 179.4 E(85289): 2e-43
Smith-Waterman score: 1034; 29.8% identity (57.1% similar) in 885 aa overlap (349-1214:1101-1895)
320 330 340 350 360 370
pF1KE5 MEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTA-FDGFHIHIEREENFTEYLMV
:. .: .. :: ... . .. .
NP_001 LSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWK
1080 1090 1100 1110 1120 1130
380 390 400 410 420 430
pF1KE5 DEEAHEFVAELKEPG-KYKLSVTTFSSSGSCE-TRKSQSAKSLSFYISPSGEWIEELTEK
:.. :. . :: :: : :.: :.. : . : .:..: : :
NP_001 DKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPS------P-----------
1140 1150 1160 1170
440 450 460 470 480 490
pF1KE5 PQHVSVHVLSSTTALMSWTSSQE--NYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSK
:. .: ...:. ..: . . .::. .. . ... . . : .. . ..
NP_001 PSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLP------RDALTVFNPYNNRKSEGR
1180 1190 1200 1210 1220
500 510 520 530 540 550
pF1KE5 PIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIV---PTGIKDLMLYPLGPTAVVLSW
:. .: :: .:: . .: : :. :. : : :..: : . ::.. ::
NP_001 -IVYGLRPGRSYQFNVKTVSGDSWKTYSKPI-FGSVRTKPDKIQNLHCRPQNSTAIACSW
1230 1240 1250 1260 1270 1280
560 570 580 590 600 610
pF1KE5 TRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTM
: . : : .: .. :. :.. : .. . : :.: : . .
NP_001 IPPD-SDFDGYSIECRKMD--TQEVEFSRKLEKEKSL-----LNIMMLVPHKRYLVSIKV
1290 1300 1310 1320 1330
620 630 640 650 660 670
pF1KE5 VTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMV
. : ..:::..: : : .. .. . :: . . :.. : :.
NP_001 QSAGMTS-EVVEDSTITMIDRP-PPPPPHIRVNEKDVLISKSSINFTVNCS------WFS
1340 1350 1360 1370 1380
680 690 700 710 720 730
pF1KE5 VAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLF
..: : :.:.. . : : . . : . : :.:. :. . . :
NP_001 DTNGAVKYFTVVVREA-DGSDELKPEQQHPLP--SYLEYRHNASI-RVYQTNYFASKCAE
1390 1400 1410 1420 1430 1440
740 750 760 770 780
pF1KE5 AVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAV-SSHVVTISSLLPATAY
:... : . .. :. .: . . .:. . :. ... ..: .. . .
NP_001 NPNSNSKSFN---IKLGAE--MESLGGKCDPTQQKFCDGPLKPHTAYRISIRAF--TQLF
1450 1460 1470 1480 1490
790 800 810 820 830 840
pF1KE5 NCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLL--VTLIILRKK
. .. :.. : ::... ..:: .: .: .. . .:::.:. :.:.: :.:
NP_001 DEDLKEFTKPLYS-DTFFSLP-ITTESEPLFGAIEGVSA-GLFLIGMLVAVVALLICRQK
1500 1510 1520 1530 1540 1550
850 860 870 880 890 900
pF1KE5 HLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKN
.. .:: .. . :..:: : . . :.: ...
NP_001 -VSHGRERPSARL----SIRRD--------RPLSVHLNL------------------GQK
1560 1570 1580
910 920 930 940 950 960
pF1KE5 GLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNR
: .:: . :.....:.... . ::.: .: ..:::: .: . : :: :: :::
NP_001 G--NRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNR
1590 1600 1610 1620 1630 1640
970 980 990 1000 1010 1020
pF1KE5 YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
:.:::::: .::.: ..... .:::::.:::: : .:::.:::::: :..:::::: .
NP_001 YNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWE
1650 1660 1670 1680 1690 1700
1030 1040 1050 1060 1070 1080
pF1KE5 QKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI---N
:. . :::.::: :: ::::::::: .. . :::. ..:.:: .:. :.:.: .
NP_001 QNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEE
1710 1720 1730 1740 1750 1760
1090 1100 1110 1120 1130 1140
pF1KE5 YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKG--PMIIHCSAGVGR
: . . ::.::.::::::: ....:..:::. ::. ..: : : ..::::::::
NP_001 QLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGR
1770 1780 1790 1800 1810 1820
1150 1160 1170 1180 1190 1200
pF1KE5 TGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK--
:::::::::.::.. ... ::: : : ..: .:. ::::: ::...::::. . .:
NP_001 TGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
1830 1840 1850 1860 1870 1880
1210
pF1KE5 -QQFCISDVIYENVSKS
.: :::::.
NP_001 SEQENPLFPIYENVNPEYHRDPVYSRH
1890 1900
>>NP_001193900 (OMIM: 176882) receptor-type tyrosine-pro (1907 aa)
initn: 947 init1: 571 opt: 1003 Z-score: 900.5 bits: 179.4 E(85289): 2e-43
Smith-Waterman score: 1034; 29.8% identity (57.1% similar) in 885 aa overlap (349-1214:1101-1895)
320 330 340 350 360 370
pF1KE5 MEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTA-FDGFHIHIEREENFTEYLMV
:. .: .. :: ... . .. .
NP_001 LSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKENWK
1080 1090 1100 1110 1120 1130
380 390 400 410 420 430
pF1KE5 DEEAHEFVAELKEPG-KYKLSVTTFSSSGSCE-TRKSQSAKSLSFYISPSGEWIEELTEK
:.. :. . :: :: : :.: :.. : . : .:..: : :
NP_001 DKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPS------P-----------
1140 1150 1160 1170
440 450 460 470 480 490
pF1KE5 PQHVSVHVLSSTTALMSWTSSQE--NYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSK
:. .: ...:. ..: . . .::. .. . ... . . : .. . ..
NP_001 PSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLP------RDALTVFNPYNNRKSEGR
1180 1190 1200 1210 1220
500 510 520 530 540 550
pF1KE5 PIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIV---PTGIKDLMLYPLGPTAVVLSW
:. .: :: .:: . .: : :. :. : : :..: : . ::.. ::
NP_001 -IVYGLRPGRSYQFNVKTVSGDSWKTYSKPI-FGSVRTKPDKIQNLHCRPQNSTAIACSW
1230 1240 1250 1260 1270 1280
560 570 580 590 600 610
pF1KE5 TRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTM
: . : : .: .. :. :.. : .. . : :.: : . .
NP_001 IPPD-SDFDGYSIECRKMD--TQEVEFSRKLEKEKSL-----LNIMMLVPHKRYLVSIKV
1290 1300 1310 1320 1330
620 630 640 650 660 670
pF1KE5 VTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMV
. : ..:::..: : : .. .. . :: . . :.. : :.
NP_001 QSAGMTS-EVVEDSTITMIDRP-PPPPPHIRVNEKDVLISKSSINFTVNCS------WFS
1340 1350 1360 1370 1380
680 690 700 710 720 730
pF1KE5 VAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLF
..: : :.:.. . : : . . : . : :.:. :. . . :
NP_001 DTNGAVKYFTVVVREA-DGSDELKPEQQHPLP--SYLEYRHNASI-RVYQTNYFASKCAE
1390 1400 1410 1420 1430 1440
740 750 760 770 780
pF1KE5 AVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAV-SSHVVTISSLLPATAY
:... : . .. :. .: . . .:. . :. ... ..: .. . .
NP_001 NPNSNSKSFN---IKLGAE--MESLGGKCDPTQQKFCDGPLKPHTAYRISIRAF--TQLF
1450 1460 1470 1480 1490
790 800 810 820 830 840
pF1KE5 NCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLL--VTLIILRKK
. .. :.. : ::... ..:: .: .: .. . .:::.:. :.:.: :.:
NP_001 DEDLKEFTKPLYS-DTFFSLP-ITTESEPLFGAIEGVSA-GLFLIGMLVAVVALLICRQK
1500 1510 1520 1530 1540 1550
850 860 870 880 890 900
pF1KE5 HLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKN
.. .:: .. . :..:: : . . :.: ...
NP_001 -VSHGRERPSARL----SIRRD--------RPLSVHLNL------------------GQK
1560 1570 1580
910 920 930 940 950 960
pF1KE5 GLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNR
: .:: . :.....:.... . ::.: .: ..:::: .: . : :: :: :::
NP_001 G--NRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNR
1590 1600 1610 1620 1630 1640
970 980 990 1000 1010 1020
pF1KE5 YTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQ
:.:::::: .::.: ..... .:::::.:::: : .:::.:::::: :..:::::: .
NP_001 YNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWE
1650 1660 1670 1680 1690 1700
1030 1040 1050 1060 1070 1080
pF1KE5 QKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI---N
:. . :::.::: :: ::::::::: .. . :::. ..:.:: .:. :.:.: .
NP_001 QNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEE
1710 1720 1730 1740 1750 1760
1090 1100 1110 1120 1130 1140
pF1KE5 YADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKG--PMIIHCSAGVGR
: . . ::.::.::::::: ....:..:::. ::. ..: : : ..::::::::
NP_001 QLDAHRLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGR
1770 1780 1790 1800 1810 1820
1150 1160 1170 1180 1190 1200
pF1KE5 TGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK--
:::::::::.::.. ... ::: : : ..: .:. ::::: ::...::::. . .:
NP_001 TGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
1830 1840 1850 1860 1870 1880
1210
pF1KE5 -QQFCISDVIYENVSKS
.: :::::.
NP_001 SEQENPLFPIYENVNPEYHRDPVYSRH
1890 1900
1216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:59:10 2016 done: Tue Nov 8 06:59:12 2016
Total Scan time: 13.250 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]