Result of FASTA (omim) for
pFN21AE5786
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5786, 707 aa
1>>>pF1KE5786 707 - 707 aa - 707 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5200+/-0.00044; mu= 13.2607+/- 0.027
mean_var=84.9335+/-16.632, 0's: 0 Z-trim(111.7): 197 B-trim: 173 in 2/54
Lambda= 0.139167
statistics sampled from 20155 (20368) to 20155 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.239), width: 16
Scan time: 9.890
The best scores are: opt bits E(85289)
NP_001153780 (OMIM: 607865) histone-lysine N-methy ( 707) 4759 966.1 0
NP_001307628 (OMIM: 607865) histone-lysine N-methy ( 707) 4330 879.9 0
NP_114121 (OMIM: 607865) histone-lysine N-methyltr ( 719) 4330 879.9 0
NP_036564 (OMIM: 604396) histone-lysine N-methyltr (1290) 857 182.7 7.7e-45
NP_001138887 (OMIM: 604396) histone-lysine N-methy (1291) 857 182.7 7.7e-45
XP_016858442 (OMIM: 604396) PREDICTED: histone-lys (1292) 857 182.7 7.7e-45
XP_005245698 (OMIM: 604396) PREDICTED: histone-lys (1292) 857 182.7 7.7e-45
XP_016858443 (OMIM: 604396) PREDICTED: histone-lys ( 739) 397 90.3 2.9e-17
NP_001263254 (OMIM: 609834) histone-lysine N-methy ( 365) 259 62.5 3.4e-09
NP_006506 (OMIM: 609834) histone-lysine N-methyltr ( 684) 259 62.6 6e-09
XP_011517333 (OMIM: 607001,610253) PREDICTED: hist ( 488) 245 59.7 3.1e-08
XP_011517332 (OMIM: 607001,610253) PREDICTED: hist ( 559) 245 59.7 3.5e-08
NP_001305762 (OMIM: 604599) histone-lysine N-methy (1008) 247 60.2 4.5e-08
XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775) 245 59.8 4.7e-08
NP_079532 (OMIM: 604599) histone-lysine N-methyltr (1176) 247 60.2 5.2e-08
XP_016865691 (OMIM: 604599) PREDICTED: histone-lys (1183) 247 60.2 5.2e-08
NP_006700 (OMIM: 604599) histone-lysine N-methyltr (1210) 247 60.2 5.4e-08
XP_006715039 (OMIM: 604599) PREDICTED: histone-lys (1217) 247 60.2 5.4e-08
NP_001276342 (OMIM: 604599) histone-lysine N-methy (1233) 247 60.2 5.4e-08
XP_006715038 (OMIM: 604599) PREDICTED: histone-lys (1240) 247 60.2 5.5e-08
XP_005248881 (OMIM: 604599) PREDICTED: histone-lys (1267) 247 60.2 5.6e-08
XP_006715037 (OMIM: 604599) PREDICTED: histone-lys (1274) 247 60.2 5.6e-08
XP_011517335 (OMIM: 607001,610253) PREDICTED: hist (1246) 245 59.8 7.3e-08
XP_011517328 (OMIM: 607001,610253) PREDICTED: hist (1253) 245 59.8 7.3e-08
XP_016870627 (OMIM: 607001,610253) PREDICTED: hist (1260) 245 59.8 7.3e-08
XP_016870626 (OMIM: 607001,610253) PREDICTED: hist (1260) 245 59.8 7.3e-08
XP_016870625 (OMIM: 607001,610253) PREDICTED: hist (1265) 245 59.8 7.4e-08
XP_011517327 (OMIM: 607001,610253) PREDICTED: hist (1267) 245 59.8 7.4e-08
XP_005266167 (OMIM: 607001,610253) PREDICTED: hist (1267) 245 59.8 7.4e-08
XP_011517326 (OMIM: 607001,610253) PREDICTED: hist (1275) 245 59.8 7.4e-08
XP_016870624 (OMIM: 607001,610253) PREDICTED: hist (1291) 245 59.8 7.5e-08
XP_006717351 (OMIM: 607001,610253) PREDICTED: hist (1292) 245 59.8 7.5e-08
XP_016870623 (OMIM: 607001,610253) PREDICTED: hist (1293) 245 59.8 7.5e-08
XP_011517325 (OMIM: 607001,610253) PREDICTED: hist (1294) 245 59.8 7.5e-08
XP_005266162 (OMIM: 607001,610253) PREDICTED: hist (1295) 245 59.8 7.5e-08
NP_079033 (OMIM: 607001,610253) histone-lysine N-m (1298) 245 59.8 7.5e-08
XP_011517324 (OMIM: 607001,610253) PREDICTED: hist (1300) 245 59.9 7.5e-08
XP_011517323 (OMIM: 607001,610253) PREDICTED: hist (1301) 245 59.9 7.5e-08
NP_001230652 (OMIM: 609834) histone-lysine N-methy ( 545) 215 53.7 2.2e-06
NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 211 52.9 3e-06
NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 211 52.9 3.1e-06
NP_001180355 (OMIM: 606503) histone-lysine N-methy ( 230) 207 52.0 3.1e-06
NP_001180356 (OMIM: 606503) histone-lysine N-methy ( 170) 197 49.9 9.5e-06
NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 197 50.0 1.8e-05
NP_001180354 (OMIM: 606503) histone-lysine N-methy ( 350) 197 50.0 1.8e-05
XP_016872126 (OMIM: 606503) PREDICTED: histone-lys ( 350) 197 50.0 1.8e-05
XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 197 50.0 1.8e-05
XP_011517964 (OMIM: 606503) PREDICTED: histone-lys ( 350) 197 50.0 1.8e-05
NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 197 50.1 2.1e-05
NP_055863 (OMIM: 611055) histone-lysine N-methyltr (1923) 201 51.1 4.9e-05
>>NP_001153780 (OMIM: 607865) histone-lysine N-methyltra (707 aa)
initn: 4759 init1: 4759 opt: 4759 Z-score: 5164.2 bits: 966.1 E(85289): 0
Smith-Waterman score: 4759; 99.7% identity (99.9% similar) in 707 aa overlap (1-707:1-707)
10 20 30 40 50 60
pF1KE5 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IINSSTSIKDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTGNKEILSLEDKVVDFR
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 IINSSTSIKDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKEILSLEDKVVDFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSALHVSYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSALHVSYK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 VPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 RNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIFSKKRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIFSKKRKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 EVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTMETKYDNISRIQYHSVIRDP
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_001 EVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNISRIQYHSVIRDP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 ESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 LIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 EELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNF
610 620 630 640 650 660
670 680 690 700
pF1KE5 PLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
670 680 690 700
>>NP_001307628 (OMIM: 607865) histone-lysine N-methyltra (707 aa)
initn: 4656 init1: 4325 opt: 4330 Z-score: 4698.7 bits: 879.9 E(85289): 0
Smith-Waterman score: 4636; 98.0% identity (98.2% similar) in 707 aa overlap (13-707:1-707)
10 20 30 40 50 60
pF1KE5 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
10 20 30 40
70 80 90 100
pF1KE5 IINSSTSIK------------DPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTGNKE
::::::::: ::::::::::::::::::::::::::::::::::: :::
NP_001 IINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE5 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE5 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE5 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE5 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE5 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE5 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTMETKYDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE5 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE5 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR
530 540 550 560 570 580
590 600 610 620 630 640
pF1KE5 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV
590 600 610 620 630 640
650 660 670 680 690 700
pF1KE5 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
650 660 670 680 690 700
>>NP_114121 (OMIM: 607865) histone-lysine N-methyltransf (719 aa)
initn: 4745 init1: 4325 opt: 4330 Z-score: 4698.6 bits: 879.9 E(85289): 0
Smith-Waterman score: 4725; 98.1% identity (98.2% similar) in 719 aa overlap (1-707:1-719)
10 20 30 40 50 60
pF1KE5 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
10 20 30 40 50 60
70 80 90 100
pF1KE5 IINSSTSIK------------DPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTGNKE
::::::::: ::::::::::::::::::::::::::::::::::: :::
NP_114 IINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE5 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTMETKYDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_114 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE5 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE5 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE5 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE5 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
670 680 690 700 710
>>NP_036564 (OMIM: 604396) histone-lysine N-methyltransf (1290 aa)
initn: 1159 init1: 764 opt: 857 Z-score: 926.0 bits: 182.7 E(85289): 7.7e-45
Smith-Waterman score: 857; 36.3% identity (62.7% similar) in 391 aa overlap (128-513:571-955)
100 110 120 130 140 150
pF1KE5 DCTFLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
: : : :: .:: .. :. . .:.:::
NP_036 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE5 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
.:. :.: :. ... ..:: :::::: ::...:. :::.:: :.::: . : .
NP_036 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE5 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
. :: . :.. : .::. : :.::.: ::::. :: : : : . :
NP_036 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE5 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
. : .:::..:: : .:::: ::: . . .: .. . ..::.::::.. .:::.::
NP_036 TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE5 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRA
:. :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.
NP_036 CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
790 800 810 820 830 840
400 410 420 430 440 450
pF1KE5 NTEKSYGIDENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKF
..: :.. . . .. .: : . : :: : . .. : .. .
NP_036 FADKE-GLEMGDEYFANLDHIESVENFKEGYESDA-----PCSSDSSGVDLKDQEDGNSG
850 860 870 880 890
460 470 480 490 500 510
pF1KE5 SNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKP
...:.: . ... ::. . . :. .: .. : :.: . .: . . :
NP_036 TEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGP
900 910 920 930 940 950
520 530 540 550 560 570
pF1KE5 PREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQN
:
NP_036 PHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRA
960 970 980 990 1000 1010
>--
initn: 381 init1: 210 opt: 380 Z-score: 408.4 bits: 87.0 E(85289): 5.2e-16
Smith-Waterman score: 380; 31.8% identity (59.7% similar) in 233 aa overlap (477-707:1073-1290)
450 460 470 480 490 500
pF1KE5 KCPPKFSNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPED
.: : :::.. :..... ..: . .:.:
NP_036 EDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSM--HQSRRL--MASAQSNPDD
1050 1060 1070 1080 1090
510 520 530 540 550 560
pF1KE5 NDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQAT
.. .....: . : . . . . . .:. :.. : ... :..
NP_036 VLTLSS-----STESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTG
1100 1110 1120 1130 1140 1150
570 580 590 600 610 620
pF1KE5 TLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCDEELLSETKNTSSDSLTKFNKG--NVF
. : :. . : .: . . : ::: .: : . .
NP_036 PMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTR-----QFYDGEESCY
1160 1170 1180 1190 1200
630 640 650 660 670 680
pF1KE5 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE
..:: :::.::.::::: :::.::::::.::. :: ::::... ..: :::::::.::
NP_036 IIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTELTWDYNYE
1210 1220 1230 1240 1250 1260
690 700
pF1KE5 AGTVPEKEIFCQCGVNKCRKKIL
.:.: ::..: ::. .:: ..:
NP_036 VGSVEGKELLCCCGAIECRGRLL
1270 1280 1290
>>NP_001138887 (OMIM: 604396) histone-lysine N-methyltra (1291 aa)
initn: 1181 init1: 764 opt: 857 Z-score: 926.0 bits: 182.7 E(85289): 7.7e-45
Smith-Waterman score: 857; 36.3% identity (62.7% similar) in 391 aa overlap (128-513:571-955)
100 110 120 130 140 150
pF1KE5 DCTFLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
: : : :: .:: .. :. . .:.:::
NP_001 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE5 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
.:. :.: :. ... ..:: :::::: ::...:. :::.:: :.::: . : .
NP_001 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE5 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
. :: . :.. : .::. : :.::.: ::::. :: : : : . :
NP_001 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE5 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
. : .:::..:: : .:::: ::: . . .: .. . ..::.::::.. .:::.::
NP_001 TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE5 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRA
:. :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.
NP_001 CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
790 800 810 820 830 840
400 410 420 430 440 450
pF1KE5 NTEKSYGIDENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKF
..: :.. . . .. .: : . : :: : . .. : .. .
NP_001 FADKE-GLEMGDEYFANLDHIESVENFKEGYESDA-----PCSSDSSGVDLKDQEDGNSG
850 860 870 880 890
460 470 480 490 500 510
pF1KE5 SNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKP
...:.: . ... ::. . . :. .: .. : :.: . .: . . :
NP_001 TEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGP
900 910 920 930 940 950
520 530 540 550 560 570
pF1KE5 PREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQN
:
NP_001 PHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRA
960 970 980 990 1000 1010
>--
initn: 415 init1: 367 opt: 391 Z-score: 420.4 bits: 89.2 E(85289): 1.1e-16
Smith-Waterman score: 391; 31.8% identity (59.7% similar) in 233 aa overlap (477-707:1073-1291)
450 460 470 480 490 500
pF1KE5 KCPPKFSNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPED
.: : :::.. :..... ..: . .:.:
NP_001 EDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSM--HQSRRL--MASAQSNPDD
1050 1060 1070 1080 1090
510 520 530 540 550 560
pF1KE5 NDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQAT
.. .....: . : . . . . . .:. :.. : ... :..
NP_001 VLTLSS-----STESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTG
1100 1110 1120 1130 1140 1150
570 580 590 600 610 620
pF1KE5 TLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCDEELLSETKNTSSDSLTKFNKG--NVF
. : :. . : .: . . : ::: .: : . .
NP_001 PMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTR-----QFYDGEESCY
1160 1170 1180 1190 1200
630 640 650 660 670 680
pF1KE5 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE
..:: :::.::.::::: :::.::::::.::. :: ::::... ..: :::::::.::
NP_001 IIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYE
1210 1220 1230 1240 1250 1260
690 700
pF1KE5 AGTVPEKEIFCQCGVNKCRKKIL
.:.: ::..: ::. .:: ..:
NP_001 VGSVEGKELLCCCGAIECRGRLL
1270 1280 1290
>>XP_016858442 (OMIM: 604396) PREDICTED: histone-lysine (1292 aa)
initn: 1147 init1: 764 opt: 857 Z-score: 926.0 bits: 182.7 E(85289): 7.7e-45
Smith-Waterman score: 857; 36.3% identity (62.7% similar) in 391 aa overlap (128-513:572-956)
100 110 120 130 140 150
pF1KE5 DCTFLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
: : : :: .:: .. :. . .:.:::
XP_016 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE5 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
.:. :.: :. ... ..:: :::::: ::...:. :::.:: :.::: . : .
XP_016 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE5 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
. :: . :.. : .::. : :.::.: ::::. :: : : : . :
XP_016 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE5 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
. : .:::..:: : .:::: ::: . . .: .. . ..::.::::.. .:::.::
XP_016 TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE5 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRA
:. :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.
XP_016 CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
790 800 810 820 830 840
400 410 420 430 440 450
pF1KE5 NTEKSYGIDENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKF
..: :.. . . .. .: : . : :: : . .. : .. .
XP_016 FADKE-GLEMGDEYFANLDHIESVENFKEGYESDA-----PCSSDSSGVDLKDQEDGNSG
850 860 870 880 890
460 470 480 490 500 510
pF1KE5 SNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKP
...:.: . ... ::. . . :. .: .. : :.: . .: . . :
XP_016 TEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGP
900 910 920 930 940 950
520 530 540 550 560 570
pF1KE5 PREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQN
:
XP_016 PHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRA
960 970 980 990 1000 1010
>--
initn: 415 init1: 367 opt: 391 Z-score: 420.4 bits: 89.2 E(85289): 1.1e-16
Smith-Waterman score: 391; 31.8% identity (59.7% similar) in 233 aa overlap (477-707:1074-1292)
450 460 470 480 490 500
pF1KE5 KCPPKFSNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPED
.: : :::.. :..... ..: . .:.:
XP_016 EDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSM--HQSRRL--MASAQSNPDD
1050 1060 1070 1080 1090
510 520 530 540 550 560
pF1KE5 NDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQAT
.. .....: . : . . . . . .:. :.. : ... :..
XP_016 VLTLSS-----STESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTG
1100 1110 1120 1130 1140 1150
570 580 590 600 610 620
pF1KE5 TLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCDEELLSETKNTSSDSLTKFNKG--NVF
. : :. . : .: . . : ::: .: : . .
XP_016 PMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTR-----QFYDGEESCY
1160 1170 1180 1190 1200
630 640 650 660 670 680
pF1KE5 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE
..:: :::.::.::::: :::.::::::.::. :: ::::... ..: :::::::.::
XP_016 IIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYE
1210 1220 1230 1240 1250 1260
690 700
pF1KE5 AGTVPEKEIFCQCGVNKCRKKIL
.:.: ::..: ::. .:: ..:
XP_016 VGSVEGKELLCCCGAIECRGRLL
1270 1280 1290
>>XP_005245698 (OMIM: 604396) PREDICTED: histone-lysine (1292 aa)
initn: 1147 init1: 764 opt: 857 Z-score: 926.0 bits: 182.7 E(85289): 7.7e-45
Smith-Waterman score: 857; 36.3% identity (62.7% similar) in 391 aa overlap (128-513:572-956)
100 110 120 130 140 150
pF1KE5 DCTFLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
: : : :: .:: .. :. . .:.:::
XP_005 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE5 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
.:. :.: :. ... ..:: :::::: ::...:. :::.:: :.::: . : .
XP_005 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE5 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
. :: . :.. : .::. : :.::.: ::::. :: : : : . :
XP_005 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE5 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
. : .:::..:: : .:::: ::: . . .: .. . ..::.::::.. .:::.::
XP_005 TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE5 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRA
:. :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.
XP_005 CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
790 800 810 820 830 840
400 410 420 430 440 450
pF1KE5 NTEKSYGIDENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKF
..: :.. . . .. .: : . : :: : . .. : .. .
XP_005 FADKE-GLEMGDEYFANLDHIESVENFKEGYESDA-----PCSSDSSGVDLKDQEDGNSG
850 860 870 880 890
460 470 480 490 500 510
pF1KE5 SNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKP
...:.: . ... ::. . . :. .: .. : :.: . .: . . :
XP_005 TEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGP
900 910 920 930 940 950
520 530 540 550 560 570
pF1KE5 PREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQN
:
XP_005 PHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRA
960 970 980 990 1000 1010
>--
initn: 415 init1: 367 opt: 391 Z-score: 420.4 bits: 89.2 E(85289): 1.1e-16
Smith-Waterman score: 391; 31.8% identity (59.7% similar) in 233 aa overlap (477-707:1074-1292)
450 460 470 480 490 500
pF1KE5 KCPPKFSNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPED
.: : :::.. :..... ..: . .:.:
XP_005 EDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSM--HQSRRL--MASAQSNPDD
1050 1060 1070 1080 1090
510 520 530 540 550 560
pF1KE5 NDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQAT
.. .....: . : . . . . . .:. :.. : ... :..
XP_005 VLTLSS-----STESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTG
1100 1110 1120 1130 1140 1150
570 580 590 600 610 620
pF1KE5 TLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCDEELLSETKNTSSDSLTKFNKG--NVF
. : :. . : .: . . : ::: .: : . .
XP_005 PMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTR-----QFYDGEESCY
1160 1170 1180 1190 1200
630 640 650 660 670 680
pF1KE5 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE
..:: :::.::.::::: :::.::::::.::. :: ::::... ..: :::::::.::
XP_005 IIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYE
1210 1220 1230 1240 1250 1260
690 700
pF1KE5 AGTVPEKEIFCQCGVNKCRKKIL
.:.: ::..: ::. .:: ..:
XP_005 VGSVEGKELLCCCGAIECRGRLL
1270 1280 1290
>>XP_016858443 (OMIM: 604396) PREDICTED: histone-lysine (739 aa)
initn: 321 init1: 321 opt: 397 Z-score: 430.8 bits: 90.3 E(85289): 2.9e-17
Smith-Waterman score: 397; 38.9% identity (61.7% similar) in 167 aa overlap (128-289:572-738)
100 110 120 130 140 150
pF1KE5 DCTFLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
: : : :: .:: .. :. . .:.:::
XP_016 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE5 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
.:. :.: :. ... ..:: :::::: ::...:. :::.:: :.::: . : .
XP_016 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE5 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
. :: . :.. : .::. : :.::.: ::::. :: : : : . :
XP_016 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE5 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
. : .:::..:: :
XP_016 TGPEFLVGCDCKDGCRDK
730
>>NP_001263254 (OMIM: 609834) histone-lysine N-methyltra (365 aa)
initn: 325 init1: 183 opt: 259 Z-score: 286.1 bits: 62.5 E(85289): 3.4e-09
Smith-Waterman score: 303; 24.3% identity (54.6% similar) in 379 aa overlap (218-588:14-356)
190 200 210 220 230 240
pF1KE5 RNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCN
.:. : . . ..:.. : :..:..
NP_001 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVG-AW
10 20 30 40
250 260 270 280 290 300
pF1KE5 EIDSRKLP-QFKYRKTVWPRAYNLTNFSSMFTDSCDCSEG-CIDITKCACLQLTARNAKT
. : :. ..: : : . ... .: : . :. : :.::. ..:
NP_001 PPGAAPAPFQYTPDHVVGPGAD--IDPTQITFPGCICVKTPCLPGT-CSCLR-HGENYDD
50 60 70 80 90
310 320 330 340 350 360
pF1KE5 SPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQK
. : : .: :: . : ..::..::.:. . :.:::::.: : ..:::::..:
NP_001 NSCLRD-IGSGGKYAE-----P--VFECNVLCRCSDH-CRNRVVQKGLQFHFQVFKTHKK
100 110 120 130 140
370 380 390 400 410 420
pF1KE5 GWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIFSKKRKLEVACS
:::.: :. : .: ::: :.:..:. ..... . .. : : . : . . .:
NP_001 GWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHL-QTKSDSNYIIAIREHVYNGQVM--
150 160 170 180 190 200
430 440 450 460 470 480
pF1KE5 DCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTMETKYDNISRIQYHSVIRDPESKTA
:. : : . . : . ..: :.. : . ... ... . .... :: . .
NP_001 --ETFVDPTYIGNIGRFLN-HSCEPNLLMIP--VRIDSMVPKLALFAAKDIV--PEEELS
210 220 230 240 250
490 500 510 520 530 540
pF1KE5 IFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESD
....:. .... ::. :. .. : ::. : . :...: .
NP_001 -YDYSGRYLNLTVSEDKERLDHGKLRKP------CYCGAK---SCTAFLPFDSSLYCPVE
260 270 280 290 300
550 560 570 580 590
pF1KE5 VIDITKYREETPPRSRCNQATTLDNQNIKKAIEV------QIQKPQEGRSTACQRQQVFC
.:. :. : : :..: .. . . ..:: :. : ::
NP_001 KSNISCGNEKEP--SMCGSAPSVFPSCKRLTLEVSLFSDKQLAPPYSGRQWLASFTSA
310 320 330 340 350 360
600 610 620 630 640 650
pF1KE5 DEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRN
>>NP_006506 (OMIM: 609834) histone-lysine N-methyltransf (684 aa)
initn: 325 init1: 183 opt: 259 Z-score: 281.6 bits: 62.6 E(85289): 6e-09
Smith-Waterman score: 296; 25.2% identity (57.7% similar) in 298 aa overlap (218-513:14-286)
190 200 210 220 230 240
pF1KE5 RNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCN
.:. : . . ..:.. : :..:..
NP_006 MFAEAAKTTRPCGMAEFKEKPEAPTEQLDVACGQENLPVG-AW
10 20 30 40
250 260 270 280 290 300
pF1KE5 EIDSRKLP-QFKYRKTVWPRAYNLTNFSSMFTDSCDCSEG-CIDITKCACLQLTARNAKT
. : :. ..: : : . ... .: : . :. : :.::. ..:
NP_006 PPGAAPAPFQYTPDHVVGPGAD--IDPTQITFPGCICVKTPCLPGT-CSCLR-HGENYDD
50 60 70 80 90
310 320 330 340 350 360
pF1KE5 SPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQK
. : : .: :: . : ..::..::.:. . :.:::::.: : ..:::::..:
NP_006 NSCLRD-IGSGGKYAE-----P--VFECNVLCRCSDH-CRNRVVQKGLQFHFQVFKTHKK
100 110 120 130 140
370 380 390 400 410 420
pF1KE5 GWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIFSKKRKLEVACS
:::.: :. : .: ::: :.:..:. ..... . .. : : . : . . .:
NP_006 GWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHL-QTKSDSNYIIAIREHVYNGQVM--
150 160 170 180 190 200
430 440 450 460 470 480
pF1KE5 DCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTMETKYDNISRIQYHSVIRDPESKTA
:. : : . . : . ..: :.. : . ... ... . .... :: . .
NP_006 --ETFVDPTYIGNIGRFLN-HSCEPNLLMIP--VRIDSMVPKLALFAAKDIV--PEEELS
210 220 230 240 250
490 500 510 520 530 540
pF1KE5 IFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESD
....:. .... ::. :. .. :
NP_006 -YDYSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLPFDSSLYCPVEKSNISCGNE
260 270 280 290 300 310
707 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:57:33 2016 done: Tue Nov 8 04:57:34 2016
Total Scan time: 9.890 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]