Result of FASTA (omim) for
pFN21AE5779
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5779, 645 aa
1>>>pF1KE5779 645 - 645 aa - 645 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5731+/-0.000411; mu= 17.9203+/- 0.026
mean_var=74.4579+/-15.116, 0's: 0 Z-trim(111.9): 21 B-trim: 134 in 1/53
Lambda= 0.148634
statistics sampled from 20670 (20691) to 20670 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.243), width: 16
Scan time: 9.210
The best scores are: opt bits E(85289)
NP_060592 (OMIM: 610956,611105) aspartate--tRNA li ( 645) 4326 937.6 0
XP_011508013 (OMIM: 610956,611105) PREDICTED: aspa ( 482) 2992 651.5 2e-186
XP_006711490 (OMIM: 610956,611105) PREDICTED: aspa ( 594) 2666 581.6 2.7e-165
XP_016878706 (OMIM: 601421,613641,613916) PREDICTE ( 441) 270 67.8 9.6e-11
NP_005539 (OMIM: 601421,613641,613916) lysine--tRN ( 597) 270 67.8 1.2e-10
NP_001123561 (OMIM: 601421,613641,613916) lysine-- ( 625) 270 67.9 1.3e-10
NP_001280241 (OMIM: 603084,615281) aspartate--tRNA ( 401) 178 48.0 7.7e-05
XP_016858978 (OMIM: 603084,615281) PREDICTED: aspa ( 468) 178 48.1 8.8e-05
NP_001340 (OMIM: 603084,615281) aspartate--tRNA li ( 501) 178 48.1 9.3e-05
XP_005266757 (OMIM: 108410) PREDICTED: asparagine- ( 547) 162 44.7 0.0011
NP_004530 (OMIM: 108410) asparagine--tRNA ligase, ( 548) 162 44.7 0.0011
>>NP_060592 (OMIM: 610956,611105) aspartate--tRNA ligase (645 aa)
initn: 4326 init1: 4326 opt: 4326 Z-score: 5011.9 bits: 937.6 E(85289): 0
Smith-Waterman score: 4326; 100.0% identity (100.0% similar) in 645 aa overlap (1-645:1-645)
10 20 30 40 50 60
pF1KE5 MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 FQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SQRLELIRLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SQRLELIRLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VVDFPLFLPKEENPRELESAHHPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VVDFPLFLPKEENPRELESAHHPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 IRIHNAELQRYILATLLKEDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IRIHNAELQRYILATLLKEDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRD
550 560 570 580 590 600
610 620 630 640
pF1KE5 VIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
:::::::::::::::::::::::::::::::::::::::::::::
NP_060 VIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
610 620 630 640
>>XP_011508013 (OMIM: 610956,611105) PREDICTED: aspartat (482 aa)
initn: 2992 init1: 2992 opt: 2992 Z-score: 3467.8 bits: 651.5 E(85289): 2e-186
Smith-Waterman score: 2992; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)
10 20 30 40 50 60
pF1KE5 MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 FQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SQRLELIRLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLW
::::::::::::::::::::::::::::
XP_011 SQRLELIRLMETQEEDVVLLTAGEHNKAKKFQSSASKLNVIPRLPFPYNSKMKKAIYFQI
430 440 450 460 470 480
>>XP_006711490 (OMIM: 610956,611105) PREDICTED: aspartat (594 aa)
initn: 3986 init1: 2666 opt: 2666 Z-score: 3088.6 bits: 581.6 E(85289): 2.7e-165
Smith-Waterman score: 3888; 92.1% identity (92.1% similar) in 645 aa overlap (1-645:1-594)
10 20 30 40 50 60
pF1KE5 MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MYFPSWLSQLYRGLSRPIRRTTQPIWGSLYRSLLQSSQRRIPEFSSFVVRTNTCGELRSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDLRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 FQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGAKEFLVPSREPGKFYSLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGIQSLIEGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQYSWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIME
:::::::::::::::::::::::::::::::::::::
XP_006 SKPHGTVKAICIPEGAKYLKRKDIESIRNFAADHFNQ-----------------------
370 380 390
430 440 450 460 470 480
pF1KE5 SQRLELIRLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLW
::::::::::::::::::::::::::::::::
XP_006 ----------------------------CSLLGKLRLECADLLETRGVVLRDPTLFSFLW
400 410 420
490 500 510 520 530 540
pF1KE5 VVDFPLFLPKEENPRELESAHHPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVDFPLFLPKEENPRELESAHHPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGS
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE5 IRIHNAELQRYILATLLKEDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IRIHNAELQRYILATLLKEDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRD
490 500 510 520 530 540
610 620 630 640
pF1KE5 VIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
:::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIAFPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
550 560 570 580 590
>>XP_016878706 (OMIM: 601421,613641,613916) PREDICTED: l (441 aa)
initn: 258 init1: 120 opt: 270 Z-score: 313.9 bits: 67.8 E(85289): 9.6e-11
Smith-Waterman score: 270; 32.4% identity (60.3% similar) in 179 aa overlap (129-301:29-202)
100 110 120 130 140 150
pF1KE5 SAASVKKILCEAPVESVVQVSGTVISRPAGQENP-KMPTGEIEIKVKTAELLNAC-KKLP
: :: : ::. : ::. : . ::
XP_016 MANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLP
10 20 30 40 50
160 170 180 190 200 210
pF1KE5 FEIKNFVKKTEALRLQYRYLDL--RSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPT
.: : . : . ::::: .: : .. .::... .: .: .: ::..::::
XP_016 HL--HFGLKDKETRYRQRYLDLILNDFVRQ-KFIIRSKIITYIRSFLDEL-GFLEIETP-
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE5 LFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRP
... :::: : :.. : . .:. ....:.:::.:: ....: .:.::
XP_016 MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE5 DRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDK
..:::: .. :...: .. . : ..
XP_016 THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP
180 190 200 210 220 230
>>NP_005539 (OMIM: 601421,613641,613916) lysine--tRNA li (597 aa)
initn: 258 init1: 120 opt: 270 Z-score: 311.9 bits: 67.8 E(85289): 1.2e-10
Smith-Waterman score: 270; 32.4% identity (60.3% similar) in 179 aa overlap (129-301:185-358)
100 110 120 130 140 150
pF1KE5 SAASVKKILCEAPVESVVQVSGTVISRPAGQENP-KMPTGEIEIKVKTAELLNAC-KKLP
: :: : ::. : ::. : . ::
NP_005 QVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 FEIKNFVKKTEALRLQYRYLDL--RSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPT
.: : . : . ::::: .: : .. .::... .: .: .: ::..::::
NP_005 HL--HFGLKDKETRYRQRYLDLILNDFVRQ-KFIIRSKIITYIRSFLDEL-GFLEIETP-
220 230 240 250 260
220 230 240 250 260 270
pF1KE5 LFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRP
... :::: : :.. : . .:. ....:.:::.:: ....: .:.::
NP_005 MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE5 DRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDK
..:::: .. :...: .. . : ..
NP_005 THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP
330 340 350 360 370 380
>>NP_001123561 (OMIM: 601421,613641,613916) lysine--tRNA (625 aa)
initn: 224 init1: 120 opt: 270 Z-score: 311.6 bits: 67.9 E(85289): 1.3e-10
Smith-Waterman score: 270; 32.4% identity (60.3% similar) in 179 aa overlap (129-301:213-386)
100 110 120 130 140 150
pF1KE5 SAASVKKILCEAPVESVVQVSGTVISRPAGQENP-KMPTGEIEIKVKTAELLNAC-KKLP
: :: : ::. : ::. : . ::
NP_001 QVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLP
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE5 FEIKNFVKKTEALRLQYRYLDL--RSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPT
.: : . : . ::::: .: : .. .::... .: .: .: ::..::::
NP_001 HL--HFGLKDKETRYRQRYLDLILNDFVRQ-KFIIRSKIITYIRSFLDEL-GFLEIETP-
250 260 270 280 290
220 230 240 250 260 270
pF1KE5 LFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRP
... :::: : :.. : . .:. ....:.:::.:: ....: .:.::
NP_001 MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE5 DRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDK
..:::: .. :...: .. . : ..
NP_001 THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP
360 370 380 390 400 410
>>NP_001280241 (OMIM: 603084,615281) aspartate--tRNA lig (401 aa)
initn: 326 init1: 104 opt: 178 Z-score: 207.8 bits: 48.0 E(85289): 7.7e-05
Smith-Waterman score: 259; 24.4% identity (47.4% similar) in 513 aa overlap (113-606:11-394)
90 100 110 120 130 140
pF1KE5 LRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIK
::.:.: :.: : ..:. . ..:..
NP_001 MVKFAANINKESIVDVEGVV--RKVNQKIGSCTQQDVELH
10 20 30
150 160 170 180
pF1KE5 VKTAELLN-ACKKLPFEIKNFVKK------------TEALRLQYRYLDLRSFQMQYNLRL
:. ... : .::... . :. .. ::. : .:::. : .::
NP_001 VQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAVFRL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE5 RSQMVMKMREYLCNLHGFVDIETPTLFKR-TPGGAKEFLVPSREPGKFYSLPQSPQQFKQ
.: . .:: : : .:::.:.:: ... . :::. : : . . . : :::: .::
NP_001 QSGICHLFRETLIN-KGFVEIQTPKIISAASEGGANVFTVSYFKNNAY--LAQSPQLYKQ
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE5 LLMVGGLDRYFQVARCYRDEGSRPDRQ-PEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPN
. . . ... :... .: : : :. ::. .::::.: . . ..: .
NP_001 MCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAF--NYHYHEVMEEI-------
160 170 180 190 200
310 320 330 340 350 360
pF1KE5 DKDPVVVPFPTMTFAEVLATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDALSKPHGTV
: .: : . . :: .: .. : . ::. .: .
NP_001 -ADTMVQIFKGL--------------QERFQTEIQTVNKQFPCEPFKFLEPTLRLEY---
210 220 230 240
370 380 390 400 410 420
pF1KE5 KAICIPEGAKYLKRKDIESIRNFAADHFNQEILPVFLNANRNWNSPVANFIMESQRLELI
: :. .:.. .: .:
NP_001 ---C--EALAMLREAGVE-----MGD----------------------------------
250 260
430 440 450 460 470 480
pF1KE5 RLMETQEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLWVVD-FPL
:.: : : .:. :::.: : : : : ...: .::
NP_001 ------EDD--LSTPNEK-----LLGHLVKEKYD------------TDF---YILDKYPL
270 280 290
490 500 510 520 530 540
pF1KE5 FLPKEENPRELESAHHPF-TAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGSIRIHN
: .:: : : : . ::.. : ::. . :.:: .:. :::.
NP_001 -------------AVRPFYTMPDPRN-------PKQSNS--YDMFMRGEEILSGAQRIHD
300 310 320 330
550 560 570 580 590 600
pF1KE5 AEL--QRYILATLLKEDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIA
.: .: . . :.. .. .... .:::::.: ..::.:. : : ..:..
NP_001 PQLLTERALHHGI---DLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSM
340 350 360 370 380 390
610 620 630 640
pF1KE5 FPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
::.
NP_001 FPRDPKRLTP
400
>>XP_016858978 (OMIM: 603084,615281) PREDICTED: aspartat (468 aa)
initn: 351 init1: 104 opt: 178 Z-score: 206.8 bits: 48.1 E(85289): 8.8e-05
Smith-Waterman score: 285; 24.4% identity (48.4% similar) in 550 aa overlap (77-606:41-461)
50 60 70 80 90 100
pF1KE5 FVVRTNTCGELRSSHLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIP-QDESAASVKK
.. :::::. . ::... :... .. :
XP_016 VLVRVRDLTIQKADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVK
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE5 ILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAELLN-ACKKLPFEIKNFVK
. . ::.:.: :.: : ..:. . ..:..:. ... : .::... . :.
XP_016 FAANINKESIVDVEGVV--RKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVR
80 90 100 110 120
170 180 190 200 210
pF1KE5 K------------TEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIET
.. ::. : .:::. : .::.: . .:: : : .:::.:.:
XP_016 PEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLIN-KGFVEIQT
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE5 PTLFKR-TPGGAKEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSR
: ... . :::. : : . . . : :::: .::. . . ... :... .: : :
XP_016 PKIISAASEGGANVFTVSYFKNNAY--LAQSPQLYKQMCICADFEKVFSIGPVFRAEDSN
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE5 PDRQ-PEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGT
:. ::. .::::.: . . ..: . : .: : .
XP_016 THRHLTEFVGLDIEMAF--NYHYHEVMEEI--------ADTMVQIFKGL-----------
250 260 270 280
340 350 360 370 380 390
pF1KE5 DKPDTRFGMKIIDISDVFRNTEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNF
. :: .: .. : . ::. .: . : :. .:.. .:
XP_016 ---QERFQTEIQTVNKQFPCEPFKFLEPTLRLEY------C--EALAMLREAGVE-----
290 300 310 320
400 410 420 430 440 450
pF1KE5 AADHFNQEILPVFLNANRNWNSPVANFIMESQRLELIRLMETQEEDVVLLTAGEHNKACS
.: :.: : : .:.
XP_016 MGD----------------------------------------EDD--LSTPNEK-----
330 340
460 470 480 490 500
pF1KE5 LLGKLRLECADLLETRGVVLRDPTLFSFLWVVD-FPLFLPKEENPRELESAHHPF-TAPH
:::.: : : : : ...: .:: : .:: : :
XP_016 LLGHLVKEKYD------------TDF---YILDKYPL-------------AVRPFYTMPD
350 360 370
510 520 530 540 550 560
pF1KE5 PSDIHLLYTEPKKARSQHYDLVLNGNEIGGGSIRIHNAEL--QRYILATLLKEDVKMLSH
: . ::.. : ::. . :.:: .:. :::. .: .: . . :.. ..
XP_016 PRN-------PKQSNS--YDMFMRGEEILSGAQRIHDPQLLTERALHHGI---DLEKIKA
380 390 400 410 420
570 580 590 600 610 620
pF1KE5 LLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPKSFRGHDLMSNTPDSVPPEEL
.... .:::::.: ..::.:. : : ..:.. ::.
XP_016 YIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP
430 440 450 460
630 640
pF1KE5 KPYHIRVSKPTDSKAERAH
>>NP_001340 (OMIM: 603084,615281) aspartate--tRNA ligase (501 aa)
initn: 351 init1: 104 opt: 178 Z-score: 206.4 bits: 48.1 E(85289): 9.3e-05
Smith-Waterman score: 285; 24.4% identity (48.4% similar) in 550 aa overlap (77-606:74-494)
50 60 70 80 90 100
pF1KE5 FVVRTNTCGELRSSHLGQEVTLCGWIQYRRQNTFLVLRDFDGLVQVIIP-QDESAASVKK
.. :::::. . ::... :... .. :
NP_001 VLVRVRDLTIQKADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVK
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE5 ILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAELLN-ACKKLPFEIKNFVK
. . ::.:.: :.: : ..:. . ..:..:. ... : .::... . :.
NP_001 FAANINKESIVDVEGVV--RKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVR
110 120 130 140 150 160
170 180 190 200 210
pF1KE5 K------------TEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIET
.. ::. : .:::. : .::.: . .:: : : .:::.:.:
NP_001 PEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLIN-KGFVEIQT
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE5 PTLFKR-TPGGAKEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSR
: ... . :::. : : . . . : :::: .::. . . ... :... .: : :
NP_001 PKIISAASEGGANVFTVSYFKNNAY--LAQSPQLYKQMCICADFEKVFSIGPVFRAEDSN
230 240 250 260 270
280 290 300 310 320 330
pF1KE5 PDRQ-PEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGT
:. ::. .::::.: . . ..: . : .: : .
NP_001 THRHLTEFVGLDIEMAF--NYHYHEVMEEI--------ADTMVQIFKGL-----------
280 290 300 310
340 350 360 370 380 390
pF1KE5 DKPDTRFGMKIIDISDVFRNTEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNF
. :: .: .. : . ::. .: . : :. .:.. .:
NP_001 ---QERFQTEIQTVNKQFPCEPFKFLEPTLRLEY------C--EALAMLREAGVE-----
320 330 340 350 360
400 410 420 430 440 450
pF1KE5 AADHFNQEILPVFLNANRNWNSPVANFIMESQRLELIRLMETQEEDVVLLTAGEHNKACS
.: :.: : : .:.
NP_001 MGD----------------------------------------EDD--LSTPNEK-----
370
460 470 480 490 500
pF1KE5 LLGKLRLECADLLETRGVVLRDPTLFSFLWVVD-FPLFLPKEENPRELESAHHPF-TAPH
:::.: : : : : ...: .:: : .:: : :
NP_001 LLGHLVKEKYD------------TDF---YILDKYPL-------------AVRPFYTMPD
380 390 400
510 520 530 540 550 560
pF1KE5 PSDIHLLYTEPKKARSQHYDLVLNGNEIGGGSIRIHNAEL--QRYILATLLKEDVKMLSH
: . ::.. : ::. . :.:: .:. :::. .: .: . . :.. ..
NP_001 PRN-------PKQSNS--YDMFMRGEEILSGAQRIHDPQLLTERALHHGI---DLEKIKA
410 420 430 440 450
570 580 590 600 610 620
pF1KE5 LLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPKSFRGHDLMSNTPDSVPPEEL
.... .:::::.: ..::.:. : : ..:.. ::.
NP_001 YIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP
460 470 480 490 500
630 640
pF1KE5 KPYHIRVSKPTDSKAERAH
>>XP_005266757 (OMIM: 108410) PREDICTED: asparagine--tRN (547 aa)
initn: 212 init1: 110 opt: 162 Z-score: 187.3 bits: 44.7 E(85289): 0.0011
Smith-Waterman score: 233; 27.5% identity (53.8% similar) in 247 aa overlap (63-301:124-357)
40 50 60 70 80
pF1KE5 LLQSSQRRIPEFSSFVVRTNTCGELRSSHLGQEVTLCGWIQY-RRQNT---FLVLRDFDG
::.: . ::.. :::. :::::: :
XP_005 LEEAKKITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTG
100 110 120 130 140 150
90 100 110 120 130 140
pF1KE5 LVQVIIPQDESAASVKKILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAEL
.: .. :: . .: .:: : : : . : :.. : : :.. ::
XP_005 YLQCVLA-DELCQCYNGVLLS--TESSVAVYGMLNLTPKGKQAP----GGHELSCDFWEL
160 170 180 190 200
150 160 170 180 190 200
pF1KE5 LNACKKLPFEIKNFVKKTEALRLQY--RYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHG
.. . :.... . .: :.. .:. .:. :. ::... .:... . .:
XP_005 IGLAPAGGAD--NLINEESDVDVQLNNRHMMIRGENMSKILKARSMVTRCFRDHFFD-RG
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 FVDIETPTLFK-RTPGGAKEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCY
. .. ::: . .. ::: : . :. : :: : . . . .: : .:. :
XP_005 YYEVTPPTLVQTQVEGGATLFKLDYF--GEEAFLTQSSQLYLETCL-PALGDVFCIAQSY
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 RDEGSRPDRQ-PEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEV
: : :: :. :.:... : :. . . .: :.
XP_005 RAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAGSIVHELNPNF
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 LATYGTDKPDTRFGMKIIDISDVFRNTEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDI
XP_005 QPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTINEPILLCRFP
390 400 410 420 430 440
>--
initn: 170 init1: 110 opt: 162 Z-score: 187.3 bits: 44.7 E(85289): 0.0011
Smith-Waterman score: 162; 29.4% identity (56.2% similar) in 153 aa overlap (463-606:399-540)
440 450 460 470 480 490
pF1KE5 QEEDVVLLTAGEHNKACSLLGKLRLECADLLETRGVVLRDPTLFSFLWVVDFPLFLPKEE
:. . : .: :.. : :.: :
XP_005 AGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGE--DIP------E
370 380 390 400 410 420
500 510 520 530 540
pF1KE5 NPREL--ESAHHP-FTAPHPSDIHLLYTE--PKKAR-SQHYDLVL-NGNEIGGGSIRIHN
:..: .. ..: . : .:. .: . :. .: .. :... : .:: :::.:: .
XP_005 APERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFD
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE5 AELQRYILATLLKEDVKMLSHL--LQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIA
.: ::: .: . . . ::. :::: .:::.:.. . . ::::
XP_005 SE---EILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCL
490 500 510 520 530
610 620 630 640
pF1KE5 FPKSFRGHDLMSNTPDSVPPEELKPYHIRVSKPTDSKAERAH
.:.
XP_005 YPRFVQRCTP
540
645 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:34:41 2016 done: Tue Nov 8 06:34:43 2016
Total Scan time: 9.210 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]