Result of FASTA (omim) for
pFN21AE5741
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5741, 623 aa
1>>>pF1KE5741 623 - 623 aa - 623 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.7840+/-0.000498; mu= -14.3554+/- 0.031
mean_var=578.6190+/-120.308, 0's: 0 Z-trim(121.0): 258 B-trim: 0 in 0/58
Lambda= 0.053318
statistics sampled from 36763 (37045) to 36763 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.434), width: 16
Scan time: 8.610
The best scores are: opt bits E(85289)
NP_055306 (OMIM: 602081,605317) forkhead box prote ( 715) 4143 334.1 9.9e-91
XP_016868290 (OMIM: 602081,605317) PREDICTED: fork ( 740) 4143 334.1 1e-90
NP_683696 (OMIM: 602081,605317) forkhead box prote ( 740) 4143 334.1 1e-90
NP_001166237 (OMIM: 602081,605317) forkhead box pr ( 714) 4124 332.7 2.7e-90
NP_683698 (OMIM: 602081,605317) forkhead box prote ( 732) 3964 320.4 1.4e-86
NP_001231737 (OMIM: 605515,613670) forkhead box pr ( 676) 2470 205.4 5.2e-52
XP_005264794 (OMIM: 605515,613670) PREDICTED: fork ( 676) 2461 204.7 8.5e-52
XP_005264793 (OMIM: 605515,613670) PREDICTED: fork ( 678) 2461 204.7 8.5e-52
XP_006713167 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
NP_001231745 (OMIM: 605515,613670) forkhead box pr ( 677) 2458 204.5 9.9e-52
XP_006713165 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
XP_006713166 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
NP_116071 (OMIM: 605515,613670) forkhead box prote ( 677) 2458 204.5 9.9e-52
XP_016861655 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
NP_001231743 (OMIM: 605515,613670) forkhead box pr ( 677) 2458 204.5 9.9e-52
XP_011531887 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
XP_016861654 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
XP_011531886 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2458 204.5 9.9e-52
XP_016861656 (OMIM: 605515,613670) PREDICTED: fork ( 677) 2456 204.3 1.1e-51
NP_001231744 (OMIM: 605515,613670) forkhead box pr ( 679) 2449 203.8 1.6e-51
XP_005264792 (OMIM: 605515,613670) PREDICTED: fork ( 678) 2444 203.4 2.1e-51
NP_001231742 (OMIM: 605515,613670) forkhead box pr ( 577) 2434 202.6 3.2e-51
XP_011531890 (OMIM: 605515,613670) PREDICTED: fork ( 577) 2434 202.6 3.2e-51
XP_005264799 (OMIM: 605515,613670) PREDICTED: fork ( 576) 2429 202.2 4.2e-51
NP_001231741 (OMIM: 605515,613670) forkhead box pr ( 601) 2404 200.3 1.6e-50
NP_683697 (OMIM: 602081,605317) forkhead box prote ( 432) 2220 186.0 2.4e-46
NP_001166238 (OMIM: 602081,605317) forkhead box pr ( 457) 2220 186.0 2.5e-46
NP_001012426 (OMIM: 608924) forkhead box protein P ( 680) 2176 182.8 3.4e-45
NP_001012427 (OMIM: 608924) forkhead box protein P ( 678) 2173 182.6 4e-45
XP_006715054 (OMIM: 608924) PREDICTED: forkhead bo ( 679) 2164 181.9 6.4e-45
XP_011512591 (OMIM: 608924) PREDICTED: forkhead bo ( 687) 2145 180.4 1.8e-44
XP_016865722 (OMIM: 608924) PREDICTED: forkhead bo ( 687) 2145 180.4 1.8e-44
XP_011512594 (OMIM: 608924) PREDICTED: forkhead bo ( 655) 2142 180.2 2e-44
XP_011512595 (OMIM: 608924) PREDICTED: forkhead bo ( 581) 2139 179.9 2.2e-44
XP_011512592 (OMIM: 608924) PREDICTED: forkhead bo ( 685) 2126 179.0 4.9e-44
XP_016865723 (OMIM: 608924) PREDICTED: forkhead bo ( 649) 2064 174.2 1.3e-42
NP_001231739 (OMIM: 605515,613670) forkhead box pr ( 693) 1933 164.1 1.5e-39
NP_612466 (OMIM: 608924) forkhead box protein P4 i ( 667) 1159 104.6 1.2e-21
XP_011512593 (OMIM: 608924) PREDICTED: forkhead bo ( 675) 1140 103.1 3.3e-21
NP_001107849 (OMIM: 222100,300292,304790) forkhead ( 396) 514 54.7 7.1e-07
NP_054728 (OMIM: 222100,300292,304790) forkhead bo ( 431) 514 54.7 7.6e-07
XP_006724596 (OMIM: 222100,300292,304790) PREDICTE ( 454) 514 54.8 7.8e-07
XP_016885055 (OMIM: 222100,300292,304790) PREDICTE ( 504) 514 54.8 8.4e-07
XP_016885054 (OMIM: 222100,300292,304790) PREDICTE ( 516) 514 54.8 8.6e-07
XP_006724326 (OMIM: 607372) PREDICTED: mediator of ( 717) 474 51.9 9e-06
XP_011537078 (OMIM: 147920,602113) PREDICTED: hist (5525) 478 53.2 2.9e-05
XP_006719679 (OMIM: 147920,602113) PREDICTED: hist (5536) 478 53.2 2.9e-05
NP_003473 (OMIM: 147920,602113) histone-lysine N-m (5537) 478 53.2 2.9e-05
XP_005269219 (OMIM: 147920,602113) PREDICTED: hist (5537) 478 53.2 2.9e-05
XP_006719677 (OMIM: 147920,602113) PREDICTED: hist (5540) 478 53.2 2.9e-05
>>NP_055306 (OMIM: 602081,605317) forkhead box protein P (715 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 1749.9 bits: 334.1 E(85289): 9.9e-91
Smith-Waterman score: 4143; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:93-715)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
::::::::::::::::::::::::::::::
NP_055 QLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE5 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE5 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE5 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE5 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
490 500 510 520 530 540
460 470 480 490 500 510
pF1KE5 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
550 560 570 580 590 600
520 530 540 550 560 570
pF1KE5 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
610 620 630 640 650 660
580 590 600 610 620
pF1KE5 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
670 680 690 700 710
>>XP_016868290 (OMIM: 602081,605317) PREDICTED: forkhead (740 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 1749.7 bits: 334.1 E(85289): 1e-90
Smith-Waterman score: 4143; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:118-740)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
::::::::::::::::::::::::::::::
XP_016 LLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE5 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE5 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE5 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
510 520 530 540 550 560
460 470 480 490 500 510
pF1KE5 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE5 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
630 640 650 660 670 680
580 590 600 610 620
pF1KE5 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
690 700 710 720 730 740
>>NP_683696 (OMIM: 602081,605317) forkhead box protein P (740 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 1749.7 bits: 334.1 E(85289): 1e-90
Smith-Waterman score: 4143; 100.0% identity (100.0% similar) in 623 aa overlap (1-623:118-740)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
::::::::::::::::::::::::::::::
NP_683 LLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE5 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE5 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE5 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
510 520 530 540 550 560
460 470 480 490 500 510
pF1KE5 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE5 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
630 640 650 660 670 680
580 590 600 610 620
pF1KE5 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
690 700 710 720 730 740
>>NP_001166237 (OMIM: 602081,605317) forkhead box protei (714 aa)
initn: 3760 init1: 3760 opt: 4124 Z-score: 1742.0 bits: 332.7 E(85289): 2.7e-90
Smith-Waterman score: 4124; 99.8% identity (99.8% similar) in 623 aa overlap (1-623:93-714)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
::::::::::::::::::::::::::::::
NP_001 QLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_001 QQQQQQQQQHPGKQAKEQQQQQQQQQ-LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSS
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE5 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQ
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE5 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKP
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE5 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDK
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE5 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR
490 500 510 520 530 540
460 470 480 490 500 510
pF1KE5 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSL
550 560 570 580 590 600
520 530 540 550 560 570
pF1KE5 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGC
610 620 630 640 650 660
580 590 600 610 620
pF1KE5 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
670 680 690 700 710
>>NP_683698 (OMIM: 602081,605317) forkhead box protein P (732 aa)
initn: 3899 init1: 3899 opt: 3964 Z-score: 1675.3 bits: 320.4 E(85289): 1.4e-86
Smith-Waterman score: 4099; 97.3% identity (97.3% similar) in 640 aa overlap (1-623:93-732)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
::::::::::::::::::::::::::::::
NP_683 QLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALL
70 80 90 100 110 120
40 50 60 70
pF1KE5 QQQQAVMLQQ-----------------QQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ
:::::::::: :::::::::::::::::::::::::::::::::
NP_683 QQQQAVMLQQDFLDSGLENFRAALEKNQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ
130 140 150 160 170 180
80 90 100 110 120 130
pF1KE5 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ
190 200 210 220 230 240
140 150 160 170 180 190
pF1KE5 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIK
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE5 HGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 HGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGH
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE5 GVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 GVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAM
370 380 390 400 410 420
320 330 340 350 360 370
pF1KE5 MTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVIT
430 440 450 460 470 480
380 390 400 410 420 430
pF1KE5 PASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 PASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQL
490 500 510 520 530 540
440 450 460 470 480 490
pF1KE5 TLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 TLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRS
550 560 570 580 590 600
500 510 520 530 540 550
pF1KE5 QKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 QKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDL
610 620 630 640 650 660
560 570 580 590 600 610
pF1KE5 NGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 NGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREI
670 680 690 700 710 720
620
pF1KE5 EEEPLSEDLE
::::::::::
NP_683 EEEPLSEDLE
730
>>NP_001231737 (OMIM: 605515,613670) forkhead box protei (676 aa)
initn: 2689 init1: 1800 opt: 2470 Z-score: 1054.7 bits: 205.4 E(85289): 5.2e-52
Smith-Waterman score: 2635; 65.3% identity (82.4% similar) in 625 aa overlap (1-623:101-676)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
:::::::::::::::::::::::::::.::
NP_001 QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
:::::.::::::::::::::::::.:::::::
NP_001 QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQ----------------------------
140 150 160
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
: ::: :::: :.:.:::.:::::::::::::: ::::::::::.
NP_001 ---------HAGKQPKEQQ-------QVATQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLL
170 180 190 200
160 170 180 190 200
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDLTTNNSSSTTS
.: ::: :::.: : : :. :.:.::::::::..:. :.. : .:..:::::. ::..
NP_001 TIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAP
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 SNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFG
:.:: : :. .::: :: . .:.: :::: :: :::::::::::::..::::
NP_001 SKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQ
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK
.::::::.:::::::::::::::::::::::.::.:..:::::::::::.. .::: .:.
NP_001 SFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQ
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 PLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSD
:::::::::.::. :.::::::.::::::::.::.:::::::: .:. .:: ::::.::
NP_001 PLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSD
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 KYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYF
:::.:.::.:: : ::::::.::::::::.::::::.:: ..::::::::.:::: ::::
NP_001 KYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYF
450 460 470 480 490 500
450 460 470 480 490 500
pF1KE5 RRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTS
::::::::::::::::::::::::::::::::::::::.:::: :::.:.:.:.::. .:
NP_001 RRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSS
510 520 530 540 550 560
510 520 530 540 550 560
pF1KE5 LGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSN-GNSSP
.: . :::.:::..::.:.:: .. .. : . ..: .:..:.:::...: .:: ..:::
NP_001 HAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSP
570 580 590 600 610 620
570 580 590 600 610 620
pF1KE5 GCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
: ::. .: .::::::. :. . :.::::::::::... ::. :.::..::.:
NP_001 GRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
630 640 650 660 670
>>XP_005264794 (OMIM: 605515,613670) PREDICTED: forkhead (676 aa)
initn: 2020 init1: 1010 opt: 2461 Z-score: 1050.9 bits: 204.7 E(85289): 8.5e-52
Smith-Waterman score: 2604; 65.0% identity (82.1% similar) in 626 aa overlap (1-623:101-676)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
:::::::::::::::::::::::::::.::
XP_005 QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
:::::.::::: ::::::::::::.:::::::
XP_005 QQQQALMLQQQ-LQEFYKKQQEQLQLQLLQQQ----------------------------
140 150 160
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
: ::: :::: :.:.:::.:::::::::::::: ::::::::::.
XP_005 ---------HAGKQPKEQQ-------QVATQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLL
170 180 190 200
160 170 180 190 200
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDLTTNNSSSTTS
.: ::: :::.: : : :. :.:.::::::::..:. :.. : .:..:::::. ::..
XP_005 TIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAP
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 SNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFG
:.:: : :. .::: :: . .:.: :::: :: :::::::::::::..::::
XP_005 SKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQ
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK
.::::::.:::::::::::::::::::::::.::.:..:::::::::::.. .::: .:.
XP_005 SFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQ
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 PLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSD
:::::::::.::. :.::::::.::::::::.::.:::::::: .:. .:: ::::.::
XP_005 PLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSD
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 KYNIPMSS-EIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAY
:::.:.:: .:: : ::::::.::::::::.::::::.:: ..::::::::.:::: :::
XP_005 KYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAY
450 460 470 480 490 500
450 460 470 480 490 500
pF1KE5 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPT
:::::::::::::::::::::::::::::::::::::::.:::: :::.:.:.:.::. .
XP_005 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQS
510 520 530 540 550 560
510 520 530 540 550 560
pF1KE5 SLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSN-GNSS
: .: . :::.:::..::.:.:: .. .. : . ..: .:..:.:::...: .:: ..::
XP_005 SHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSS
570 580 590 600 610 620
570 580 590 600 610 620
pF1KE5 PGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:: ::. .: .::::::. :. . :.::::::::::... ::. :.::..::.:
XP_005 PGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
630 640 650 660 670
>>XP_005264793 (OMIM: 605515,613670) PREDICTED: forkhead (678 aa)
initn: 2684 init1: 1800 opt: 2461 Z-score: 1050.9 bits: 204.7 E(85289): 8.5e-52
Smith-Waterman score: 2635; 65.3% identity (82.4% similar) in 625 aa overlap (1-623:103-678)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
:::::::::::::::::::::::::::.::
XP_005 QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
:::::.::::::::::::::::::.:::::::
XP_005 QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQ----------------------------
140 150 160
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
: ::: :::: :.:.:::.:::::::::::::: ::::::::::.
XP_005 ---------HAGKQPKEQQ-------QVATQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLL
170 180 190 200
160 170 180 190 200
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDLTTNNSSSTTS
.: ::: :::.: : : :. :.:.::::::::..:. :.. : .:..:::::. ::..
XP_005 TIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAP
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 SNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFG
:.:: : :. .::: :: . .:.: :::: :: :::::::::::::..::::
XP_005 SKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQ
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK
.::::::.:::::::::::::::::::::::.::.:..:::::::::::.. .::: .:.
XP_005 SFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQ
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 PLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSD
:::::::::.::. :.::::::.::::::::.::.:::::::: .:. .:: ::::.::
XP_005 PLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSD
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 KYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYF
:::.:.::.:: : ::::::.::::::::.::::::.:: ..::::::::.:::: ::::
XP_005 KYNVPISSDIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYF
450 460 470 480 490 500
450 460 470 480 490 500
pF1KE5 RRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTS
::::::::::::::::::::::::::::::::::::::.:::: :::.:.:.:.::. .:
XP_005 RRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSS
510 520 530 540 550 560
510 520 530 540 550 560
pF1KE5 LGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSN-GNSSP
.: . :::.:::..::.:.:: .. .. : . ..: .:..:.:::...: .:: ..:::
XP_005 HAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSP
570 580 590 600 610 620
570 580 590 600 610 620
pF1KE5 GCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
: ::. .: .::::::. :. . :.::::::::::... ::. :.::..::.:
XP_005 GRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
630 640 650 660 670
>>XP_006713167 (OMIM: 605515,613670) PREDICTED: forkhead (677 aa)
initn: 1792 init1: 1010 opt: 2458 Z-score: 1049.7 bits: 204.5 E(85289): 9.9e-52
Smith-Waterman score: 2623; 65.2% identity (82.3% similar) in 626 aa overlap (1-623:101-677)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
:::::::::::::::::::::::::::.::
XP_006 QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
:::::.::::::::::::::::::.:::::::
XP_006 QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQ----------------------------
140 150 160
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
: ::: :::: :.:.:::.:::::::::::::: ::::::::::.
XP_006 ---------HAGKQPKEQQ-------QVATQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLL
170 180 190 200
160 170 180 190 200
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDLTTNNSSSTTS
.: ::: :::.: : : :. :.:.::::::::..:. :.. : .:..:::::. ::..
XP_006 TIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAP
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 SNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFG
:.:: : :. .::: :: . .:.: :::: :: :::::::::::::..::::
XP_006 SKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQ
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK
.::::::.:::::::::::::::::::::::.::.:..:::::::::::.. .::: .:.
XP_006 SFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQ
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 PLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSD
:::::::::.::. :.::::::.::::::::.::.:::::::: .:. .:: ::::.::
XP_006 PLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSD
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 KYNIPMSS-EIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAY
:::.:.:: .:: : ::::::.::::::::.::::::.:: ..::::::::.:::: :::
XP_006 KYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAY
450 460 470 480 490 500
450 460 470 480 490 500
pF1KE5 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPT
:::::::::::::::::::::::::::::::::::::::.:::: :::.:.:.:.::. .
XP_006 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQS
510 520 530 540 550 560
510 520 530 540 550 560
pF1KE5 SLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSN-GNSS
: .: . :::.:::..::.:.:: .. .. : . ..: .:..:.:::...: .:: ..::
XP_006 SHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSS
570 580 590 600 610 620
570 580 590 600 610 620
pF1KE5 PGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:: ::. .: .::::::. :. . :.::::::::::... ::. :.::..::.:
XP_006 PGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
630 640 650 660 670
>>NP_001231745 (OMIM: 605515,613670) forkhead box protei (677 aa)
initn: 1792 init1: 1010 opt: 2458 Z-score: 1049.7 bits: 204.5 E(85289): 9.9e-52
Smith-Waterman score: 2623; 65.2% identity (82.3% similar) in 626 aa overlap (1-623:101-677)
10 20 30
pF1KE5 MMTPQVITPQQMQQILQQQVLSPQQLQALL
:::::::::::::::::::::::::::.::
NP_001 QQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE5 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
:::::.::::::::::::::::::.:::::::
NP_001 QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQ----------------------------
140 150 160
100 110 120 130 140 150
pF1KE5 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI
: ::: :::: :.:.:::.:::::::::::::: ::::::::::.
NP_001 ---------HAGKQPKEQQ-------QVATQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLL
170 180 190 200
160 170 180 190 200
pF1KE5 SIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN-GIKHGGLDLTTNNSSSTTS
.: ::: :::.: : : :. :.:.::::::::..:. :.. : .:..:::::. ::..
NP_001 TIQPGQPALPLQPLAQ-GMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAP
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE5 SNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFG
:.:: : :. .::: :: . .:.: :::: :: :::::::::::::..::::
NP_001 SKTSLIMNP---HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQ
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 QFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPK
.::::::.:::::::::::::::::::::::.::.:..:::::::::::.. .::: .:.
NP_001 SFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQ
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 PLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSD
:::::::::.::. :.::::::.::::::::.::.:::::::: .:. .:: ::::.::
NP_001 PLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSD
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 KYNIPMSS-EIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAY
:::.:.:: .:: : ::::::.::::::::.::::::.:: ..::::::::.:::: :::
NP_001 KYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAY
450 460 470 480 490 500
450 460 470 480 490 500
pF1KE5 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPT
:::::::::::::::::::::::::::::::::::::::.:::: :::.:.:.:.::. .
NP_001 FRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQS
510 520 530 540 550 560
510 520 530 540 550 560
pF1KE5 SLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSN-GNSS
: .: . :::.:::..::.:.:: .. .. : . ..: .:..:.:::...: .:: ..::
NP_001 SHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSS
570 580 590 600 610 620
570 580 590 600 610 620
pF1KE5 PGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
:: ::. .: .::::::. :. . :.::::::::::... ::. :.::..::.:
NP_001 PGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
630 640 650 660 670
623 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:17:01 2016 done: Tue Nov 8 06:17:02 2016
Total Scan time: 8.610 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]