Result of FASTA (omim) for
pFN21AE5732
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5732, 636 aa
1>>>pF1KE5732 636 - 636 aa - 636 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4978+/-0.000414; mu= 23.8856+/- 0.026
mean_var=66.3010+/-13.849, 0's: 0 Z-trim(110.1): 105 B-trim: 62 in 1/49
Lambda= 0.157512
statistics sampled from 18225 (18350) to 18225 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.215), width: 16
Scan time: 8.720
The best scores are: opt bits E(85289)
NP_055043 (OMIM: 606205) sodium-dependent proline ( 636) 4311 989.3 0
XP_016865259 (OMIM: 606205) PREDICTED: sodium-depe ( 555) 3731 857.4 0
XP_016865257 (OMIM: 606205) PREDICTED: sodium-depe ( 592) 2963 682.9 8.4e-196
XP_016865258 (OMIM: 606205) PREDICTED: sodium-depe ( 592) 2963 682.9 8.4e-196
XP_016865256 (OMIM: 606205) PREDICTED: sodium-depe ( 754) 2963 683.0 9.9e-196
NP_057699 (OMIM: 615097) sodium- and chloride-depe ( 602) 1833 426.2 1.7e-118
NP_001116320 (OMIM: 603080) sodium- and chloride-d ( 614) 1809 420.7 7.5e-117
XP_011519312 (OMIM: 603080) PREDICTED: sodium- and ( 614) 1809 420.7 7.5e-117
NP_001116319 (OMIM: 603080) sodium- and chloride-d ( 614) 1809 420.7 7.5e-117
NP_001193860 (OMIM: 603080) sodium- and chloride-d ( 614) 1809 420.7 7.5e-117
NP_003035 (OMIM: 603080) sodium- and chloride-depe ( 614) 1809 420.7 7.5e-117
XP_005253805 (OMIM: 603080) PREDICTED: sodium- and ( 571) 1790 416.4 1.4e-115
XP_006719068 (OMIM: 603080) PREDICTED: sodium- and ( 570) 1787 415.7 2.3e-115
XP_005253804 (OMIM: 603080) PREDICTED: sodium- and ( 610) 1787 415.7 2.4e-115
NP_005620 (OMIM: 300036,300352) sodium- and chlori ( 635) 1781 414.4 6.3e-115
NP_055044 (OMIM: 607952) sodium- and chloride-depe ( 632) 1773 412.5 2.2e-114
NP_001165972 (OMIM: 163970,604715) sodium-dependen ( 617) 1742 405.5 2.9e-112
NP_001034 (OMIM: 163970,604715) sodium-dependent n ( 617) 1742 405.5 2.9e-112
XP_011521597 (OMIM: 163970,604715) PREDICTED: sodi ( 628) 1742 405.5 2.9e-112
NP_001165975 (OMIM: 163970,604715) sodium-dependen ( 628) 1742 405.5 2.9e-112
XP_006721326 (OMIM: 163970,604715) PREDICTED: sodi ( 628) 1742 405.5 2.9e-112
NP_001136277 (OMIM: 300036,300352) sodium- and chl ( 625) 1727 402.1 3.1e-111
XP_011532332 (OMIM: 186854) PREDICTED: sodium- and ( 620) 1717 399.8 1.5e-110
NP_003034 (OMIM: 186854) sodium- and chloride-depe ( 620) 1717 399.8 1.5e-110
XP_006713370 (OMIM: 186854) PREDICTED: sodium- and ( 649) 1717 399.8 1.5e-110
NP_001127839 (OMIM: 186854) sodium- and chloride-d ( 721) 1717 399.9 1.6e-110
NP_001035 (OMIM: 126455,188890,613135) sodium-depe ( 620) 1713 398.9 2.8e-110
NP_001036 (OMIM: 164230,182138,607834) sodium-depe ( 630) 1655 385.7 2.6e-106
NP_001248309 (OMIM: 601019) sodium- and chloride-d ( 637) 1627 379.4 2.2e-104
NP_001020016 (OMIM: 601019) sodium- and chloride-d ( 633) 1528 356.9 1.3e-97
NP_001315558 (OMIM: 601019) sodium- and chloride-d ( 633) 1528 356.9 1.3e-97
NP_008865 (OMIM: 601019) sodium- and chloride-depe ( 652) 1528 356.9 1.3e-97
NP_964012 (OMIM: 601019) sodium- and chloride-depe ( 706) 1528 356.9 1.4e-97
NP_001315555 (OMIM: 601019) sodium- and chloride-d ( 522) 1526 356.3 1.5e-97
NP_001315557 (OMIM: 601019) sodium- and chloride-d ( 568) 1526 356.4 1.6e-97
XP_016857642 (OMIM: 601019) PREDICTED: sodium- and ( 595) 1526 356.4 1.7e-97
XP_016857641 (OMIM: 601019) PREDICTED: sodium- and ( 606) 1526 356.4 1.7e-97
NP_001315556 (OMIM: 601019) sodium- and chloride-d ( 612) 1526 356.4 1.7e-97
XP_016874034 (OMIM: 604159,614618) PREDICTED: sodi ( 450) 1487 347.4 6.4e-95
XP_016874033 (OMIM: 604159,614618) PREDICTED: sodi ( 505) 1487 347.5 6.9e-95
NP_001305298 (OMIM: 604159,614618) sodium- and chl ( 563) 1487 347.5 7.5e-95
NP_004202 (OMIM: 604159,614618) sodium- and chlori ( 797) 1487 347.7 9.6e-95
XP_011519314 (OMIM: 615097) PREDICTED: sodium- and ( 483) 1469 343.4 1.1e-93
NP_001136278 (OMIM: 300036,300352) sodium- and chl ( 520) 1460 341.3 5e-93
XP_016875333 (OMIM: 615097) PREDICTED: sodium- and ( 394) 1418 331.7 3.1e-90
NP_001165973 (OMIM: 163970,604715) sodium-dependen ( 512) 1380 323.2 1.5e-87
NP_001177926 (OMIM: 615097) sodium- and chloride-d ( 510) 1313 307.9 5.6e-83
XP_011519315 (OMIM: 615097) PREDICTED: sodium- and ( 440) 1304 305.8 2.1e-82
XP_011519316 (OMIM: 615097) PREDICTED: sodium- and ( 440) 1304 305.8 2.1e-82
NP_009162 (OMIM: 300306,300444) sodium- and chlori ( 642) 1278 300.1 1.6e-80
>>NP_055043 (OMIM: 606205) sodium-dependent proline tran (636 aa)
initn: 4311 init1: 4311 opt: 4311 Z-score: 5291.4 bits: 989.3 E(85289): 0
Smith-Waterman score: 4311; 99.8% identity (100.0% similar) in 636 aa overlap (1-636:1-636)
10 20 30 40 50 60
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 AMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 PKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPPWAELLGI
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_055 RFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 LMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQS
550 560 570 580 590 600
610 620 630
pF1KE5 PKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
::::::::::::::::::::::::::::::::::::
NP_055 PKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
610 620 630
>>XP_016865259 (OMIM: 606205) PREDICTED: sodium-dependen (555 aa)
initn: 3731 init1: 3731 opt: 3731 Z-score: 4579.8 bits: 857.4 E(85289): 0
Smith-Waterman score: 3731; 99.8% identity (100.0% similar) in 555 aa overlap (82-636:1-555)
60 70 80 90 100 110
pF1KE5 GYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKI
::::::::::::::::::::::::::::::
XP_016 MLAICGIPLFFLELSLGQFSSLGPLAVWKI
10 20 30
120 130 140 150 160 170
pF1KE5 SPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRV
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE5 SKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLC
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE5 ILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEA
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE5 ALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQE
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE5 LGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAV
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE5 TDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCL
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE5 AVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRF
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_016 AVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRF
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE5 PPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMY
460 470 480 490 500 510
600 610 620 630
pF1KE5 VATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
520 530 540 550
>>XP_016865257 (OMIM: 606205) PREDICTED: sodium-dependen (592 aa)
initn: 2956 init1: 2956 opt: 2963 Z-score: 3636.3 bits: 682.9 E(85289): 8.4e-196
Smith-Waterman score: 3647; 93.6% identity (93.8% similar) in 592 aa overlap (82-636:1-592)
60 70 80 90 100 110
pF1KE5 GYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKI
::::::::::::::::::::::::::::::
XP_016 MLAICGIPLFFLELSLGQFSSLGPLAVWKI
10 20 30
120 130 140 150 160 170
pF1KE5 SPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRV
40 50 60 70 80 90
180 190
pF1KE5 SKDGNGALPLNLTCTVSPSEEYWS------------------------------------
::::::::::::::::::::::::
XP_016 SKDGNGALPLNLTCTVSPSEEYWSQTHTEAEEEGRRGRVVSNSYPQVIFLPQPPKAEEGV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE5 -RYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLIL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE5 LMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE5 FHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQA
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE5 MTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAM
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE5 YLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKP
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE5 GLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGM
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 GLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGM
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE5 LVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGI
520 530 540 550 560 570
620 630
pF1KE5 TSFENTAIEVDREIAEEEESMM
::::::::::::::::::::::
XP_016 TSFENTAIEVDREIAEEEESMM
580 590
>>XP_016865258 (OMIM: 606205) PREDICTED: sodium-dependen (592 aa)
initn: 2956 init1: 2956 opt: 2963 Z-score: 3636.3 bits: 682.9 E(85289): 8.4e-196
Smith-Waterman score: 3647; 93.6% identity (93.8% similar) in 592 aa overlap (82-636:1-592)
60 70 80 90 100 110
pF1KE5 GYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKI
::::::::::::::::::::::::::::::
XP_016 MLAICGIPLFFLELSLGQFSSLGPLAVWKI
10 20 30
120 130 140 150 160 170
pF1KE5 SPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRV
40 50 60 70 80 90
180 190
pF1KE5 SKDGNGALPLNLTCTVSPSEEYWS------------------------------------
::::::::::::::::::::::::
XP_016 SKDGNGALPLNLTCTVSPSEEYWSQTHTEAEEEGRRGRVVSNSYPQVIFLPQPPKAEEGV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE5 -RYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLIL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE5 LMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE5 FHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQA
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE5 MTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAM
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE5 YLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKP
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE5 GLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGM
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 GLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGM
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE5 LVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGI
520 530 540 550 560 570
620 630
pF1KE5 TSFENTAIEVDREIAEEEESMM
::::::::::::::::::::::
XP_016 TSFENTAIEVDREIAEEEESMM
580 590
>>XP_016865256 (OMIM: 606205) PREDICTED: sodium-dependen (754 aa)
initn: 2956 init1: 2956 opt: 2963 Z-score: 3635.0 bits: 683.0 E(85289): 9.9e-196
Smith-Waterman score: 4196; 94.3% identity (94.5% similar) in 668 aa overlap (6-636:87-754)
10 20 30
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAA
::::::::::::::::::::::::::::::
XP_016 GQRTISRALALCAPGQLSPGHPLSKMKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAA
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 HRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLEL
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE5 SLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWE
180 190 200 210 220 230
160 170 180 190
pF1KE5 HCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWS--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 HCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSQTHTEAEEEGRRGRVVSNSY
240 250 260 270 280 290
200 210 220 230
pF1KE5 -----------------RYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKS
:::::::::::::::::::::::::::::::::::::::::::
XP_016 PQVIFLPQPPKAEEGVSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKS
300 310 320 330 340 350
240 250 260 270 280 290
pF1KE5 SGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYS
360 370 380 390 400 410
300 310 320 330 340 350
pF1KE5 LGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQ
420 430 440 450 460 470
360 370 380 390 400 410
pF1KE5 VAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYY
480 490 500 510 520 530
420 430 440 450 460 470
pF1KE5 LRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYG
540 550 560 570 580 590
480 490 500 510 520 530
pF1KE5 IQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPPWAELL
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_016 IQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELL
600 610 620 630 640 650
540 550 560 570 580 590
pF1KE5 GILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGS
660 670 680 690 700 710
600 610 620 630
pF1KE5 QSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
::::::::::::::::::::::::::::::::::::::
XP_016 QSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
720 730 740 750
>>NP_057699 (OMIM: 615097) sodium- and chloride-dependen (602 aa)
initn: 1762 init1: 905 opt: 1833 Z-score: 2248.4 bits: 426.2 E(85289): 1.7e-118
Smith-Waterman score: 1834; 48.5% identity (75.0% similar) in 573 aa overlap (11-578:15-573)
10 20 30 40 50
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVG
::: : .: ... : . .::.:..:..:.:: : .:
NP_057 MDSRVSGTTSNGETKPVYP--VMEKKEE-------DGTLERGHWNNKMEFVLSVAGEIIG
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 LGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVW-KISPLF
::::::::: : ::::::..::...: ::::.:.:: .:::..: : ...: :: :.:
NP_057 LGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 KGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDG
.: : : .:: :. .:: ...:..:::::.:.: :::: : . :::: :.: . .
NP_057 EGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKT---
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 NGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKG
::.: . ..:: :.: : ::.: :.:: : .::.: ::::::::: ..:: ::
NP_057 NGSLNGTSENATSPVIEFWERRVLKI--SDGIQHLGALRWELALCLLLAWVICYFCIWKG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 VKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQI
:::.:::::::::::::.:..::.:::::::: .:::::: :.. .: . .::..:. ::
NP_057 VKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQI
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE5 FYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVP
:.:... .: : ...::: .:.: ::: . . . :. ::..:::::::.::.:::: :::
NP_057 FFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVP
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE5 VDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEF
...::..::::::..::.:..:::.::.:. ::::.. :::::::. .:..:::..: .
NP_057 ISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMY
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE5 PYYLRPK--KAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSAS-FGLMVVVITTCLA
:. .: : . :. . :. .:.:::. :.:::: . :.: :.:: . :. :.: :
NP_057 PHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLC
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE5 VTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGS-YRF
:. ::: .:: .:. :.:..: .. :::::.::. : ...:..:: : :.. : .
NP_057 VAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTY
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE5 PPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMY
: :.. :: :..: : . ::: : . .: . ::..: :: :
NP_057 PWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQRNPAGPSAPA
530 540 550 560 570 580
600 610 620 630
pF1KE5 VATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
NP_057 TPRTSLLRLTELESHC
590 600
>>NP_001116320 (OMIM: 603080) sodium- and chloride-depen (614 aa)
initn: 1569 init1: 877 opt: 1809 Z-score: 2218.8 bits: 420.7 E(85289): 7.5e-117
Smith-Waterman score: 1809; 46.9% identity (75.6% similar) in 569 aa overlap (15-575:13-575)
10 20 30 40 50
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDL-DVDFAAHRGNWTGKLDFLLSCIGYCVGLGN
: . .: . .: : : . ::.::.:..:.:: : .::::
NP_001 MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 VWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVW-KISPLFKGA
:::::: : ::::::..:::... .::::.::::..:::..: : ...: :: :::.:
NP_001 VWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGA
: : ..: . . .:: .:.:..:::::.:.::.::: :.:.:::: : . ....: :.
NP_001 GLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF-LNHSGAGT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 L-PL-NLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGV
. :. :.: :: :.: : :: : ..:: . : .::.: ::::::::: ..:: :::
NP_001 VTPFENFT---SPVMEFWERRVLGI--TSGIHDLGSLRWELALCLLLAWVICYFCIWKGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 KSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIF
::.:::::::::::::.:..::.::::::::..:: .:: :.. .: . .::..:. :::
NP_001 KSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 YSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPV
.:... : : ...::: .:.: :.: . . . :. ::..:::..::.::.:::: :::.
NP_001 FSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 DQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFP
..::..::::::...:.:.::.::: .:: :::.::. :::::::. .: .::: : ::
NP_001 SEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 YYLRP--KKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSAS-FGLMVVVITTCLAV
:: .. .. : : ::.::.:.:.:::: . :.: :..: . :. . . . .
NP_001 RQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCI
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE5 TRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGS-YRFP
. ::: .:: .:. :.:..: . ::::.:. :: ...:. :: : .:.. : .:
NP_001 SWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE5 PWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYV
::. .: ...: : . .: .....:. .: . .::.: :
NP_001 PWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSA
540 550 560 570 580 590
600 610 620 630
pF1KE5 ATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
NP_001 GRNFGPSPTREGLIAGEKETHL
600 610
>>XP_011519312 (OMIM: 603080) PREDICTED: sodium- and chl (614 aa)
initn: 1569 init1: 877 opt: 1809 Z-score: 2218.8 bits: 420.7 E(85289): 7.5e-117
Smith-Waterman score: 1809; 46.9% identity (75.6% similar) in 569 aa overlap (15-575:13-575)
10 20 30 40 50
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDL-DVDFAAHRGNWTGKLDFLLSCIGYCVGLGN
: . .: . .: : : . ::.::.:..:.:: : .::::
XP_011 MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 VWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVW-KISPLFKGA
:::::: : ::::::..:::... .::::.::::..:::..: : ...: :: :::.:
XP_011 VWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGA
: : ..: . . .:: .:.:..:::::.:.::.::: :.:.:::: : . ....: :.
XP_011 GLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF-LNHSGAGT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 L-PL-NLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGV
. :. :.: :: :.: : :: : ..:: . : .::.: ::::::::: ..:: :::
XP_011 VTPFENFT---SPVMEFWERRVLGI--TSGIHDLGSLRWELALCLLLAWVICYFCIWKGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 KSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIF
::.:::::::::::::.:..::.::::::::..:: .:: :.. .: . .::..:. :::
XP_011 KSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 YSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPV
.:... : : ...::: .:.: :.: . . . :. ::..:::..::.::.:::: :::.
XP_011 FSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 DQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFP
..::..::::::...:.:.::.::: .:: :::.::. :::::::. .: .::: : ::
XP_011 SEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 YYLRP--KKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSAS-FGLMVVVITTCLAV
:: .. .. : : ::.::.:.:.:::: . :.: :..: . :. . . . .
XP_011 RQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCI
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE5 TRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGS-YRFP
. ::: .:: .:. :.:..: . ::::.:. :: ...:. :: : .:.. : .:
XP_011 SWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE5 PWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYV
::. .: ...: : . .: .....:. .: . .::.: :
XP_011 PWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSA
540 550 560 570 580 590
600 610 620 630
pF1KE5 ATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
XP_011 GRNFGPSPTREGLIAGEKETHL
600 610
>>NP_001116319 (OMIM: 603080) sodium- and chloride-depen (614 aa)
initn: 1569 init1: 877 opt: 1809 Z-score: 2218.8 bits: 420.7 E(85289): 7.5e-117
Smith-Waterman score: 1809; 46.9% identity (75.6% similar) in 569 aa overlap (15-575:13-575)
10 20 30 40 50
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDL-DVDFAAHRGNWTGKLDFLLSCIGYCVGLGN
: . .: . .: : : . ::.::.:..:.:: : .::::
NP_001 MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 VWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVW-KISPLFKGA
:::::: : ::::::..:::... .::::.::::..:::..: : ...: :: :::.:
NP_001 VWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGA
: : ..: . . .:: .:.:..:::::.:.::.::: :.:.:::: : . ....: :.
NP_001 GLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF-LNHSGAGT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 L-PL-NLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGV
. :. :.: :: :.: : :: : ..:: . : .::.: ::::::::: ..:: :::
NP_001 VTPFENFT---SPVMEFWERRVLGI--TSGIHDLGSLRWELALCLLLAWVICYFCIWKGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 KSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIF
::.:::::::::::::.:..::.::::::::..:: .:: :.. .: . .::..:. :::
NP_001 KSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 YSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPV
.:... : : ...::: .:.: :.: . . . :. ::..:::..::.::.:::: :::.
NP_001 FSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 DQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFP
..::..::::::...:.:.::.::: .:: :::.::. :::::::. .: .::: : ::
NP_001 SEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 YYLRP--KKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSAS-FGLMVVVITTCLAV
:: .. .. : : ::.::.:.:.:::: . :.: :..: . :. . . . .
NP_001 RQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCI
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE5 TRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGS-YRFP
. ::: .:: .:. :.:..: . ::::.:. :: ...:. :: : .:.. : .:
NP_001 SWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE5 PWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYV
::. .: ...: : . .: .....:. .: . .::.: :
NP_001 PWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSA
540 550 560 570 580 590
600 610 620 630
pF1KE5 ATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
NP_001 GRNFGPSPTREGLIAGEKETHL
600 610
>>NP_001193860 (OMIM: 603080) sodium- and chloride-depen (614 aa)
initn: 1569 init1: 877 opt: 1809 Z-score: 2218.8 bits: 420.7 E(85289): 7.5e-117
Smith-Waterman score: 1809; 46.9% identity (75.6% similar) in 569 aa overlap (15-575:13-575)
10 20 30 40 50
pF1KE5 MKKLQGAHLRKPVTPDLLMTPSDQGDVDL-DVDFAAHRGNWTGKLDFLLSCIGYCVGLGN
: . .: . .: : : . ::.::.:..:.:: : .::::
NP_001 MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 VWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVW-KISPLFKGA
:::::: : ::::::..:::... .::::.::::..:::..: : ...: :: :::.:
NP_001 VWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGA
: : ..: . . .:: .:.:..:::::.:.::.::: :.:.:::: : . ....: :.
NP_001 GLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDF-LNHSGAGT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 L-PL-NLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGV
. :. :.: :: :.: : :: : ..:: . : .::.: ::::::::: ..:: :::
NP_001 VTPFENFT---SPVMEFWERRVLGI--TSGIHDLGSLRWELALCLLLAWVICYFCIWKGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 KSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIF
::.:::::::::::::.:..::.::::::::..:: .:: :.. .: . .::..:. :::
NP_001 KSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 YSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPV
.:... : : ...::: .:.: :.: . . . :. ::..:::..::.::.:::: :::.
NP_001 FSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 DQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFP
..::..::::::...:.:.::.::: .:: :::.::. :::::::. .: .::: : ::
NP_001 SEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 YYLRP--KKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSAS-FGLMVVVITTCLAV
:: .. .. : : ::.::.:.:.:::: . :.: :..: . :. . . . .
NP_001 RQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCI
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE5 TRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGS-YRFP
. ::: .:: .:. :.:..: . ::::.:. :: ...:. :: : .:.. : .:
NP_001 SWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE5 PWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYV
::. .: ...: : . .: .....:. .: . .::.: :
NP_001 PWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSA
540 550 560 570 580 590
600 610 620 630
pF1KE5 ATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM
NP_001 GRNFGPSPTREGLIAGEKETHL
600 610
636 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:10:48 2016 done: Tue Nov 8 06:10:49 2016
Total Scan time: 8.720 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]