Result of FASTA (omim) for
pFN21AE5710
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5710, 845 aa
1>>>pF1KE5710 845 - 845 aa - 845 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.4989+/-0.000433; mu= -7.8785+/- 0.027
mean_var=349.8267+/-71.723, 0's: 0 Z-trim(121.4): 29 B-trim: 1884 in 1/56
Lambda= 0.068572
statistics sampled from 37946 (38000) to 37946 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.446), width: 16
Scan time: 13.170
The best scores are: opt bits E(85289)
NP_001020262 (OMIM: 603429) ATP-binding cassette s ( 845) 5546 563.2 1.7e-159
NP_001081 (OMIM: 603429) ATP-binding cassette sub- ( 807) 3937 404.0 1.4e-111
XP_016867128 (OMIM: 612510) PREDICTED: ATP-binding ( 623) 1404 153.4 3.1e-36
XP_016867129 (OMIM: 612510) PREDICTED: ATP-binding ( 623) 1404 153.4 3.1e-36
NP_009120 (OMIM: 612510) ATP-binding cassette sub- ( 623) 1404 153.4 3.1e-36
NP_005683 (OMIM: 612510) ATP-binding cassette sub- ( 634) 1404 153.4 3.1e-36
>>NP_001020262 (OMIM: 603429) ATP-binding cassette sub-f (845 aa)
initn: 5546 init1: 5546 opt: 5546 Z-score: 2984.3 bits: 563.2 E(85289): 1.7e-159
Smith-Waterman score: 5546; 99.9% identity (99.9% similar) in 845 aa overlap (1-845:1-845)
10 20 30 40 50 60
pF1KE5 MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 RGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVPEEQQPALKGKKGKE
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 RGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 GGESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 ASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 ATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 HLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 LLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 GVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 DARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 LGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMV
790 800 810 820 830 840
pF1KE5 SRPRE
:::::
NP_001 SRPRE
>>NP_001081 (OMIM: 603429) ATP-binding cassette sub-fami (807 aa)
initn: 3874 init1: 3874 opt: 3937 Z-score: 2124.3 bits: 404.0 E(85289): 1.4e-111
Smith-Waterman score: 5214; 95.4% identity (95.4% similar) in 845 aa overlap (1-845:1-807)
10 20 30 40 50 60
pF1KE5 MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 RGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVPEEQQPALKGKKGKE
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 RGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEE
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAE---------------
190 200 210 220
250 260 270 280 290 300
pF1KE5 GGESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLEN
:::::::::::::::::::::::::::::::::::::
NP_001 -----------------------QMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLEN
230 240 250 260
310 320 330 340 350 360
pF1KE5 ASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNI
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE5 DVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE5 ATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTN
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE5 HLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMY
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE5 QQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPE
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE5 LLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPN
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE5 GVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQ
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE5 DARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDA
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE5 LGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMV
750 760 770 780 790 800
pF1KE5 SRPRE
:::::
NP_001 SRPRE
>>XP_016867128 (OMIM: 612510) PREDICTED: ATP-binding cas (623 aa)
initn: 1383 init1: 525 opt: 1404 Z-score: 771.6 bits: 153.4 E(85289): 3.1e-36
Smith-Waterman score: 1413; 38.1% identity (70.5% similar) in 627 aa overlap (213-831:2-605)
190 200 210 220 230 240
pF1KE5 SKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGG
: .:.:: : ..... . . .. .::.:
XP_016 MPSDLAKKKAAKKKEAAKARQRPRKGHEENG
10 20 30
250 260 270 280 290
pF1KE5 ESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLE---
. . .: ....:.. . .. : . . :. :: ...: . ..:
XP_016 DV-VTEP--QVAEKNEANGRETTEVDLLTKELE-------DFEMKKAAARAVTGVLASHP
40 50 60 70 80
300 310 320 330 340 350
pF1KE5 NASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPN
:..:... ..:.. ::.::. .. : . .::::::.: :: ::. ::. :..: . :: .
XP_016 NSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEH
90 100 110 120 130 140
360 370 380 390 400 410
pF1KE5 IDVLLCEQEVV-ADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEE
::. .:. .:.:: .. :...::.: : .: .:: .:. :.: ..::.
XP_016 IDIYHLTREMPPSDKTP-LHCVMEVDTERAMLEKEAERLAH-----EDAECEKLMELYER
150 160 170 180 190
420 430 440 450 460 470
pF1KE5 LRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEP
:. : :: .: ::: :::: : :: . . :::::::::.::::::..: .:.::::
XP_016 LEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEP
200 210 220 230 240 250
480 490 500 510 520 530
pF1KE5 TNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKK
::::::.: .::.. :. ... :..:::.: ::. :::.:::. ..:.:: ::: . :
XP_016 TNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVK
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE5 MYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEA
. ... .:... .. .. ..: . .. .. ..: :.:. :. :.. ... :
XP_016 TRLELEENQMKRFHWEQDQIAHMK--NYIARFGHGSAK--LARQAQS---KEKTLQKMMA
320 330 340 350 360
600 610 620 630 640 650
pF1KE5 PELLKRP-KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRICI
: .: .. :. : :: . :::. ...:.: : . : ...::.::::.:.:. .
XP_016 SGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVAL
370 380 390 400 410 420
660 670 680 690 700 710
pF1KE5 VGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFN
:::::.:::::: ::::.: :: : .::. ..::: ..:. ::: .. .: ::... .
XP_016 VGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYP
430 440 450 460 470 480
720 730 740 750 760 770
pF1KE5 L--PYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLD
.. :: .::.:: .. .. : .:: ::: :: .: :: ..: .:.::::::.::
XP_016 EIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLD
490 500 510 520 530 540
780 790 800 810 820 830
pF1KE5 IESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEA
::.::::..::::..:....:::: ::: .. ..:: :.:.... ::. ::...
XP_016 IETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSK
550 560 570 580 590 600
840
pF1KE5 LGEVMVSRPRE
XP_016 LVDEEPQLTKRTHNV
610 620
>>XP_016867129 (OMIM: 612510) PREDICTED: ATP-binding cas (623 aa)
initn: 1383 init1: 525 opt: 1404 Z-score: 771.6 bits: 153.4 E(85289): 3.1e-36
Smith-Waterman score: 1413; 38.1% identity (70.5% similar) in 627 aa overlap (213-831:2-605)
190 200 210 220 230 240
pF1KE5 SKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGG
: .:.:: : ..... . . .. .::.:
XP_016 MPSDLAKKKAAKKKEAAKARQRPRKGHEENG
10 20 30
250 260 270 280 290
pF1KE5 ESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLE---
. . .: ....:.. . .. : . . :. :: ...: . ..:
XP_016 DV-VTEP--QVAEKNEANGRETTEVDLLTKELE-------DFEMKKAAARAVTGVLASHP
40 50 60 70 80
300 310 320 330 340 350
pF1KE5 NASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPN
:..:... ..:.. ::.::. .. : . .::::::.: :: ::. ::. :..: . :: .
XP_016 NSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEH
90 100 110 120 130 140
360 370 380 390 400 410
pF1KE5 IDVLLCEQEVV-ADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEE
::. .:. .:.:: .. :...::.: : .: .:: .:. :.: ..::.
XP_016 IDIYHLTREMPPSDKTP-LHCVMEVDTERAMLEKEAERLAH-----EDAECEKLMELYER
150 160 170 180 190
420 430 440 450 460 470
pF1KE5 LRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEP
:. : :: .: ::: :::: : :: . . :::::::::.::::::..: .:.::::
XP_016 LEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEP
200 210 220 230 240 250
480 490 500 510 520 530
pF1KE5 TNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKK
::::::.: .::.. :. ... :..:::.: ::. :::.:::. ..:.:: ::: . :
XP_016 TNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVK
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE5 MYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEA
. ... .:... .. .. ..: . .. .. ..: :.:. :. :.. ... :
XP_016 TRLELEENQMKRFHWEQDQIAHMK--NYIARFGHGSAK--LARQAQS---KEKTLQKMMA
320 330 340 350 360
600 610 620 630 640 650
pF1KE5 PELLKRP-KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRICI
: .: .. :. : :: . :::. ...:.: : . : ...::.::::.:.:. .
XP_016 SGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVAL
370 380 390 400 410 420
660 670 680 690 700 710
pF1KE5 VGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFN
:::::.:::::: ::::.: :: : .::. ..::: ..:. ::: .. .: ::... .
XP_016 VGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYP
430 440 450 460 470 480
720 730 740 750 760 770
pF1KE5 L--PYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLD
.. :: .::.:: .. .. : .:: ::: :: .: :: ..: .:.::::::.::
XP_016 EIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLD
490 500 510 520 530 540
780 790 800 810 820 830
pF1KE5 IESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEA
::.::::..::::..:....:::: ::: .. ..:: :.:.... ::. ::...
XP_016 IETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSK
550 560 570 580 590 600
840
pF1KE5 LGEVMVSRPRE
XP_016 LVDEEPQLTKRTHNV
610 620
>>NP_009120 (OMIM: 612510) ATP-binding cassette sub-fami (623 aa)
initn: 1383 init1: 525 opt: 1404 Z-score: 771.6 bits: 153.4 E(85289): 3.1e-36
Smith-Waterman score: 1413; 38.1% identity (70.5% similar) in 627 aa overlap (213-831:2-605)
190 200 210 220 230 240
pF1KE5 SKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGG
: .:.:: : ..... . . .. .::.:
NP_009 MPSDLAKKKAAKKKEAAKARQRPRKGHEENG
10 20 30
250 260 270 280 290
pF1KE5 ESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLE---
. . .: ....:.. . .. : . . :. :: ...: . ..:
NP_009 DV-VTEP--QVAEKNEANGRETTEVDLLTKELE-------DFEMKKAAARAVTGVLASHP
40 50 60 70 80
300 310 320 330 340 350
pF1KE5 NASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPN
:..:... ..:.. ::.::. .. : . .::::::.: :: ::. ::. :..: . :: .
NP_009 NSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEH
90 100 110 120 130 140
360 370 380 390 400 410
pF1KE5 IDVLLCEQEVV-ADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEE
::. .:. .:.:: .. :...::.: : .: .:: .:. :.: ..::.
NP_009 IDIYHLTREMPPSDKTP-LHCVMEVDTERAMLEKEAERLAH-----EDAECEKLMELYER
150 160 170 180 190
420 430 440 450 460 470
pF1KE5 LRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEP
:. : :: .: ::: :::: : :: . . :::::::::.::::::..: .:.::::
NP_009 LEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEP
200 210 220 230 240 250
480 490 500 510 520 530
pF1KE5 TNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKK
::::::.: .::.. :. ... :..:::.: ::. :::.:::. ..:.:: ::: . :
NP_009 TNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVK
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE5 MYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEA
. ... .:... .. .. ..: . .. .. ..: :.:. :. :.. ... :
NP_009 TRLELEENQMKRFHWEQDQIAHMK--NYIARFGHGSAK--LARQAQS---KEKTLQKMMA
320 330 340 350 360
600 610 620 630 640 650
pF1KE5 PELLKRP-KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRICI
: .: .. :. : :: . :::. ...:.: : . : ...::.::::.:.:. .
NP_009 SGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVAL
370 380 390 400 410 420
660 670 680 690 700 710
pF1KE5 VGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFN
:::::.:::::: ::::.: :: : .::. ..::: ..:. ::: .. .: ::... .
NP_009 VGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYP
430 440 450 460 470 480
720 730 740 750 760 770
pF1KE5 L--PYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLD
.. :: .::.:: .. .. : .:: ::: :: .: :: ..: .:.::::::.::
NP_009 EIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLD
490 500 510 520 530 540
780 790 800 810 820 830
pF1KE5 IESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEA
::.::::..::::..:....:::: ::: .. ..:: :.:.... ::. ::...
NP_009 IETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSK
550 560 570 580 590 600
840
pF1KE5 LGEVMVSRPRE
NP_009 LVDEEPQLTKRTHNV
610 620
>>NP_005683 (OMIM: 612510) ATP-binding cassette sub-fami (634 aa)
initn: 1383 init1: 525 opt: 1404 Z-score: 771.5 bits: 153.4 E(85289): 3.1e-36
Smith-Waterman score: 1413; 38.1% identity (70.5% similar) in 627 aa overlap (213-831:2-605)
190 200 210 220 230 240
pF1KE5 SKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGG
: .:.:: : ..... . . .. .::.:
NP_005 MPSDLAKKKAAKKKEAAKARQRPRKGHEENG
10 20 30
250 260 270 280 290
pF1KE5 ESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLE---
. . .: ....:.. . .. : . . :. :: ...: . ..:
NP_005 DV-VTEP--QVAEKNEANGRETTEVDLLTKELE-------DFEMKKAAARAVTGVLASHP
40 50 60 70 80
300 310 320 330 340 350
pF1KE5 NASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPN
:..:... ..:.. ::.::. .. : . .::::::.: :: ::. ::. :..: . :: .
NP_005 NSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEH
90 100 110 120 130 140
360 370 380 390 400 410
pF1KE5 IDVLLCEQEVV-ADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEE
::. .:. .:.:: .. :...::.: : .: .:: .:. :.: ..::.
NP_005 IDIYHLTREMPPSDKTP-LHCVMEVDTERAMLEKEAERLAH-----EDAECEKLMELYER
150 160 170 180 190
420 430 440 450 460 470
pF1KE5 LRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEP
:. : :: .: ::: :::: : :: . . :::::::::.::::::..: .:.::::
NP_005 LEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEP
200 210 220 230 240 250
480 490 500 510 520 530
pF1KE5 TNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKK
::::::.: .::.. :. ... :..:::.: ::. :::.:::. ..:.:: ::: . :
NP_005 TNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVK
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE5 MYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEA
. ... .:... .. .. ..: . .. .. ..: :.:. :. :.. ... :
NP_005 TRLELEENQMKRFHWEQDQIAHMK--NYIARFGHGSAK--LARQAQS---KEKTLQKMMA
320 330 340 350 360
600 610 620 630 640 650
pF1KE5 PELLKRP-KEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRICI
: .: .. :. : :: . :::. ...:.: : . : ...::.::::.:.:. .
NP_005 SGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVAL
370 380 390 400 410 420
660 670 680 690 700 710
pF1KE5 VGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFN
:::::.:::::: ::::.: :: : .::. ..::: ..:. ::: .. .: ::... .
NP_005 VGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYP
430 440 450 460 470 480
720 730 740 750 760 770
pF1KE5 L--PYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLD
.. :: .::.:: .. .. : .:: ::: :: .: :: ..: .:.::::::.::
NP_005 EIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLD
490 500 510 520 530 540
780 790 800 810 820 830
pF1KE5 IESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEA
::.::::..::::..:....:::: ::: .. ..:: :.:.... ::. ::...
NP_005 IETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSK
550 560 570 580 590 600
840
pF1KE5 LGEVMVSRPRE
NP_005 LVDEEPQLTKRTHNVCTLTLASLPRP
610 620 630
845 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:18:19 2016 done: Tue Nov 8 04:18:21 2016
Total Scan time: 13.170 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]