Result of FASTA (ccds) for
pFN21AE5701
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5701, 748 aa
1>>>pF1KE5701 748 - 748 aa - 748 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0066+/-0.000963; mu= 13.2100+/- 0.058
mean_var=130.7402+/-25.657, 0's: 0 Z-trim(109.3): 21 B-trim: 151 in 1/52
Lambda= 0.112168
statistics sampled from 10776 (10781) to 10776 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.331), width: 16
Scan time: 3.960
The best scores are: opt bits E(32554)
CCDS7742.1 CARS gene_id:833|Hs108|chr11 ( 748) 5011 822.8 0
CCDS41600.1 CARS gene_id:833|Hs108|chr11 ( 831) 4957 814.1 0
CCDS41602.1 CARS gene_id:833|Hs108|chr11 ( 726) 4729 777.1 0
CCDS9514.1 CARS2 gene_id:79587|Hs108|chr13 ( 564) 668 119.9 1.1e-26
>>CCDS7742.1 CARS gene_id:833|Hs108|chr11 (748 aa)
initn: 5011 init1: 5011 opt: 5011 Z-score: 4389.0 bits: 822.8 E(32554): 0
Smith-Waterman score: 5011; 100.0% identity (100.0% similar) in 748 aa overlap (1-748:1-748)
10 20 30 40 50 60
pF1KE5 MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 DASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 SCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 VSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 EGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 DIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 EKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 IAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 IAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 KRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 KRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQ
670 680 690 700 710 720
730 740
pF1KE5 AKKLKKLFEAQEKLYKEYLQMAQNGSFQ
::::::::::::::::::::::::::::
CCDS77 AKKLKKLFEAQEKLYKEYLQMAQNGSFQ
730 740
>>CCDS41600.1 CARS gene_id:833|Hs108|chr11 (831 aa)
initn: 4957 init1: 4957 opt: 4957 Z-score: 4341.1 bits: 814.1 E(32554): 0
Smith-Waterman score: 4957; 99.7% identity (99.9% similar) in 742 aa overlap (7-748:90-831)
10 20 30
pF1KE5 MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLT
: .:::::::::::::::::::::::::::
CCDS41 DPQLFHVARWFRHIEALLGSPCGKGQPCRLQASKGRRVQPQWSPPAGTQPCRLHLYNSLT
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 RNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 RNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNIT
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE5 DIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQ
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE5 HAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 HAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLP
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE5 KFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFA
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE5 SSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCP
360 370 380 390 400 410
340 350 360 370 380 390
pF1KE5 WGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 WGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLH
420 430 440 450 460 470
400 410 420 430 440 450
pF1KE5 TGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 TGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYE
480 490 500 510 520 530
460 470 480 490 500 510
pF1KE5 KFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVME
540 550 560 570 580 590
520 530 540 550 560 570
pF1KE5 EMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGT
600 610 620 630 640 650
580 590 600 610 620 630
pF1KE5 SLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLP
660 670 680 690 700 710
640 650 660 670 680 690
pF1KE5 TVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 TVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETD
720 730 740 750 760 770
700 710 720 730 740
pF1KE5 KYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
780 790 800 810 820 830
>>CCDS41602.1 CARS gene_id:833|Hs108|chr11 (726 aa)
initn: 4725 init1: 4725 opt: 4729 Z-score: 4142.5 bits: 777.1 E(32554): 0
Smith-Waterman score: 4729; 97.7% identity (98.3% similar) in 725 aa overlap (1-722:1-725)
10 20 30 40 50 60
pF1KE5 MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 VSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 EGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 EKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 QALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 IAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 IAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEE
610 620 630 640 650 660
670 680 690 700 710
pF1KE5 KRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENG---LPTHDMEGKELS
:::::::::::::::::::::::::::::::::::::::::::: : ..: .
CCDS41 KRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENVSMVCPHMTWRAKSSA
670 680 690 700 710 720
720 730 740
pF1KE5 KGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
::. .
CCDS41 KGKPRS
>>CCDS9514.1 CARS2 gene_id:79587|Hs108|chr13 (564 aa)
initn: 1083 init1: 437 opt: 668 Z-score: 592.5 bits: 119.9 E(32554): 1.1e-26
Smith-Waterman score: 954; 32.9% identity (54.4% similar) in 662 aa overlap (2-646:30-557)
10 20 30
pF1KE5 MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLY
: ... :.:: : :.: . ...:
CCDS95 MLRTTRGPGLGPPLLQAALGLGRAGWHWPAGRAASGGRGR----AWLQPTGRETG-VQVY
10 20 30 40 50
40 50 60 70 80 90
pF1KE5 NSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYC
:::: :: .: .. ..:: ::::::: .:.::: ::. :::.::.: : .. .
CCDS95 NSLTGRKEPLIVAHAEAASWYSCGPTVYDHAHLGHACSYVRFDIIRRILTKVFGCSIVMV
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE5 MNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQML
:.:::.:::::::: ::
CCDS95 MGITDVDDKIIKRA----------------------------------NE----------
120 130
160 170 180 190 200 210
pF1KE5 ERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIF
. :
CCDS95 --------MNISP-----------------------------------------------
220 230 240 250 260 270
pF1KE5 SKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGY-VSNGSVYFD
..: ...: ::..:: ::.:::: : ::.: .:.:..:.. :. : .: ...:.::::
CCDS95 ASLASLYEEDFKQDMAALKVLPPTVYLRVTENIPQIISFIEGIIARGNAYSTAKGNVYFD
140 150 160 170 180 190
280 290 300 310 320 330
pF1KE5 TAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEP
.:. .::::: . : :: :: :.:: .:::::::.:: :
CCDS95 L----KSRGDKYGKLVGVVPGPV-----GE-----PAD--SDKRHASDFALWKAAKPQEV
200 210 220 230 240
340 350 360 370 380 390
pF1KE5 SWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWV
: ::: :::::::::::.:. ..:...:::.::.:: ::::.::.:: :.. . . :
CCDS95 FWASPWGPGRPGWHIECSAIASMVFGSQLDIHSGGIDLAFPHHENEIAQCEVFHQCEQWG
250 260 270 280 290 300
400 410 420 430 440
pF1KE5 RYFLHTGHLTIAGC--KMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTM
::::.::: : ::::::::.::::: :: : .:. : :.....:::...:
CCDS95 NYFLHSGHLHAKGKEEKMSKSLKNYITIKDFLKTFSPDVFRFFCLRSSYRSAIDYSDSAM
310 320 330 340 350 360
450 460 470 480 490 500
pF1KE5 ESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNV
.: : :. :. ... .. ::. . .:: : . . . : :.. :: :.
CCDS95 LQAQQLLLGLGSFLEDARAYMK------GQLACGSVREAMLWERLSSTKRAVKAALADDF
370 380 390 400 410
510 520 530 540 550 560
pF1KE5 DTRTVMEEMRALVSQCNLYMAARKAVRKRP-NQALLENIALYLTHMLKIFGAVEEDSSLG
:: :.. . .:. . : . : . : . :.. : :. .... : ...
CCDS95 DTPRVVDAILGLAHHGNGQLRASLKEPEGPRSPAVFGAIISYFEQFFETVGISLANQQY-
420 430 440 450 460 470
570 580 590 600 610
pF1KE5 FPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIA----------REQKVPE---ILQLSD
:.: :. :::. .. : .::. ::..: :.:.. : .:. :
CCDS95 --VSGDGS----EATLHGVVDELVRFRQKVRQFALAMPEATGDARRQQLLERQPLLEACD
480 490 500 510 520
620 630 640 650 660 670
pF1KE5 ALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQ
.:: . : :. ..:. . .. .:.:. :
CCDS95 TLRRG-LTAHGINIKDRSSTTSTWELLDQRTKDQKSAG
530 540 550 560
680 690 700 710 720 730
pF1KE5 EAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLY
748 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:54:23 2016 done: Tue Nov 8 05:54:24 2016
Total Scan time: 3.960 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]