Result of FASTA (omim) for
pFN21AE5694
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5694, 540 aa
1>>>pF1KE5694 540 - 540 aa - 540 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9546+/-0.000367; mu= 16.0801+/- 0.023
mean_var=101.6462+/-20.282, 0's: 0 Z-trim(115.4): 137 B-trim: 207 in 1/54
Lambda= 0.127212
statistics sampled from 25632 (25796) to 25632 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.302), width: 16
Scan time: 9.120
The best scores are: opt bits E(85289)
NP_060850 (OMIM: 607618) probable ATP-dependent RN ( 540) 3518 656.5 5.7e-188
NP_004809 (OMIM: 612172) probable ATP-dependent RN ( 820) 580 117.5 1.6e-25
NP_065147 (OMIM: 606181) ATP-dependent RNA helicas ( 859) 365 78.0 1.3e-13
XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 354 76.0 4.8e-13
XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 354 76.0 5.5e-13
NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 354 76.0 5.5e-13
XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 354 76.0 5.5e-13
NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 354 76.0 5.5e-13
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 332 71.8 5.3e-12
NP_619526 (OMIM: 616533) probable ATP-dependent RN ( 585) 327 70.9 1.2e-11
NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 328 71.3 1.4e-11
NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 328 71.3 1.4e-11
XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 324 70.4 2e-11
XP_011527190 (OMIM: 616621) PREDICTED: probable AT ( 827) 324 70.5 2.3e-11
NP_001244118 (OMIM: 608023) probable ATP-dependent ( 507) 310 67.8 9.4e-11
NP_061955 (OMIM: 608023) probable ATP-dependent RN ( 547) 310 67.8 9.9e-11
XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390) 304 66.6 1.6e-10
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 304 66.6 1.7e-10
XP_016884803 (OMIM: 300160,300958) PREDICTED: ATP- ( 475) 287 63.5 1.7e-09
XP_016884802 (OMIM: 300160,300958) PREDICTED: ATP- ( 476) 287 63.5 1.7e-09
XP_011542194 (OMIM: 300160,300958) PREDICTED: ATP- ( 598) 287 63.6 2e-09
NP_001180346 (OMIM: 300160,300958) ATP-dependent R ( 646) 287 63.6 2.1e-09
XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 286 63.4 2.1e-09
NP_001180345 (OMIM: 300160,300958) ATP-dependent R ( 661) 287 63.6 2.1e-09
NP_001347 (OMIM: 300160,300958) ATP-dependent RNA ( 662) 287 63.6 2.1e-09
NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 286 63.4 2.2e-09
XP_005245576 (OMIM: 174300,615464) PREDICTED: prob ( 576) 286 63.4 2.2e-09
NP_001191439 (OMIM: 602641) eukaryotic initiation ( 347) 280 62.1 3.2e-09
NP_001289481 (OMIM: 400010,415000) ATP-dependent R ( 657) 282 62.7 4e-09
NP_001116137 (OMIM: 400010,415000) ATP-dependent R ( 660) 282 62.7 4e-09
NP_004651 (OMIM: 400010,415000) ATP-dependent RNA ( 660) 282 62.7 4e-09
XP_016872399 (OMIM: 606357) PREDICTED: nucleolar R ( 661) 282 62.7 4e-09
NP_001243839 (OMIM: 606357) nucleolar RNA helicase ( 715) 282 62.7 4.3e-09
XP_011538638 (OMIM: 606357) PREDICTED: nucleolar R ( 729) 282 62.7 4.3e-09
NP_001311124 (OMIM: 400010,415000) ATP-dependent R ( 637) 281 62.5 4.5e-09
NP_004719 (OMIM: 606357) nucleolar RNA helicase 2 ( 783) 282 62.8 4.6e-09
NP_001160006 (OMIM: 605281) probable ATP-dependent ( 575) 274 61.2 1e-08
XP_011541799 (OMIM: 605281) PREDICTED: probable AT ( 678) 274 61.3 1.1e-08
NP_001136021 (OMIM: 605281) probable ATP-dependent ( 690) 274 61.3 1.2e-08
XP_011541797 (OMIM: 605281) PREDICTED: probable AT ( 698) 274 61.3 1.2e-08
NP_001160005 (OMIM: 605281) probable ATP-dependent ( 704) 274 61.3 1.2e-08
NP_077726 (OMIM: 605281) probable ATP-dependent RN ( 724) 274 61.3 1.2e-08
NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369) 263 59.0 2.9e-08
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 265 59.6 3.3e-08
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 265 59.6 3.3e-08
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 265 59.6 3.3e-08
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 265 59.6 3.3e-08
XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482) 263 59.1 3.6e-08
NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483) 263 59.1 3.6e-08
XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486) 263 59.1 3.6e-08
>>NP_060850 (OMIM: 607618) probable ATP-dependent RNA he (540 aa)
initn: 3518 init1: 3518 opt: 3518 Z-score: 3495.6 bits: 656.5 E(85289): 5.7e-188
Smith-Waterman score: 3518; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540)
10 20 30 40 50 60
pF1KE5 MALTRPVRLFSLVTRLLLAPRRGLTVRSPDEPLPVVRIPVALQRQLEQRQSRRRNLPRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MALTRPVRLFSLVTRLLLAPRRGLTVRSPDEPLPVVRIPVALQRQLEQRQSRRRNLPRPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LVRPGPLLVSARRPELNQPARLTLGRWERAPLASQGWKSRRARRDHFSIERAQQEAPAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LVRPGPLLVSARRPELNQPARLTLGRWERAPLASQGWKSRRARRDHFSIERAQQEAPAVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQSSTIPSLLRGRHVVCAAETGSGKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQSSTIPSLLRGRHVVCAAETGSGKTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVRDLEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVRDLEGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 HGMRRIRLQLSRQPSADVLVATPGALWKALKSRLISLEQLSFLVLDEADTLLDESFLELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HGMRRIRLQLSRQPSADVLVATPGALWKALKSRLISLEQLSFLVLDEADTLLDESFLELV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTTITSSKLHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTTITSSKLHC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IMPHVKQTFLRLKGADKVAELVHILKHRDRAERTGPSGTVLVFCNSSSTVNWLGYILDDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IMPHVKQTFLRLKGADKVAELVHILKHRDRAERTGPSGTVLVFCNSSSTVNWLGYILDDH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 KIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 YIHRAGRVGRVGSEVPGTVISFVTHPWDVSLVQKIELAARRRRSLPGLASSVKEPLPQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YIHRAGRVGRVGSEVPGTVISFVTHPWDVSLVQKIELAARRRRSLPGLASSVKEPLPQAT
490 500 510 520 530 540
>>NP_004809 (OMIM: 612172) probable ATP-dependent RNA he (820 aa)
initn: 424 init1: 253 opt: 580 Z-score: 579.0 bits: 117.5 E(85289): 1.6e-25
Smith-Waterman score: 592; 29.0% identity (58.5% similar) in 451 aa overlap (72-504:344-769)
50 60 70 80 90 100
pF1KE5 LQRQLEQRQSRRRNLPRPVLVRPGPLLVSARRPELNQPARLTLGRWERAPLASQGWKSRR
:. : .: : .: . : . .. :
NP_004 REQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQ--RWDDRHWSQKKLDEMTDRDWR
320 330 340 350 360 370
110 120 130 140 150 160
pF1KE5 ARRDHFSIERAQQEAPA-VRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQSSTIP
:. .:: . : .: :. : .: :..:..... . . .:: .: ..::
NP_004 IFREDYSITTKGGKIPNPIR------SWKDSSLPPHILEVIDKCGYK--EPTPIQRQAIP
380 390 400 410 420
170 180 190 200 210
pF1KE5 SLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIP--APRGLVLVPSRELAQQ
:..: .. .:::::::: ..:.::: . :..: . .: ...:.:.::::::
NP_004 IGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQ
430 440 450 460 470 480
220 230 240 250 260 270
pF1KE5 VRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLISLE
.. . .:. :: .: . :. : . . . ....:::: : .:..: . :
NP_004 IEEETIKFGKPLG--IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLS
490 500 510 520 530 540
280 290 300 310 320
pF1KE5 QLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKA-------------Q
. ...:::::: ..: .: :. :::. ... : .. .:. :
NP_004 RCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQ
550 560 570 580 590 600
330 340 350 360 370 380
pF1KE5 LVLVGATFPEGVGQLLNKVASPDAVTTITSSKLHCIMPH--VKQTFLRLKGADKVAELVH
:. ::.: .: .: . ::. : :. :: :.: . .. ..: .:.
NP_004 TVMFTATMPPAVERLARSYLRRPAVVYIGSAG----KPHERVEQKVFLMSESEKRKKLLA
610 620 630 640 650
390 400 410 420 430 440
pF1KE5 ILKHRDRAERTGPSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSF
::.. : . ...: :... . :. :. . :.: .: ....
NP_004 ILEQ-------GFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNL
660 670 680 690 700 710
450 460 470 480 490 500
pF1KE5 QKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFV
. ...:::. ::.:.::.: : .:::::. ...::::: ::.::.:. :..:.:.
NP_004 KAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGK--SGVAITFL
720 730 740 750 760
510 520 530 540
pF1KE5 THPWDVSLVQKIELAARRRRSLPGLASSVKEPLPQAT
:
NP_004 TKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA
770 780 790 800 810 820
>>NP_065147 (OMIM: 606181) ATP-dependent RNA helicase DD (859 aa)
initn: 450 init1: 190 opt: 365 Z-score: 365.5 bits: 78.0 E(85289): 1.3e-13
Smith-Waterman score: 395; 29.3% identity (57.1% similar) in 338 aa overlap (206-526:390-713)
180 190 200 210 220 230
pF1KE5 SGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVR
::::.:.:::: ::. . ..: :. .
NP_065 NLDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTA
360 370 380 390 400 410
240 250 260 270 280 290
pF1KE5 DLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSR---LISLEQLSFLVLDEADTLL
: :: . .. . .:.:.: ...::::: ::. .: . : .:.:: ::.:::: ..
NP_065 ILVGGMSTQKQQRMLNRRP--EIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMV
420 430 440 450 460 470
300 310 320 330 340 350
pF1KE5 DESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTT
... . .. .:: . .. .::: : .. .::. : : .. .
NP_065 EKGHFAELSQLLEMLN--------DSQYNPKRQTLVFSATLTL-VHQAPARILHKKHTKK
480 490 500 510 520
360 370 380 390
pF1KE5 IT-SSKLHCIMPHV----KQTFLRLKGADKVAELVHILK-HRDRAERT--------GPSG
. ..:: .: .. : . : . ..: . : : . :. :
NP_065 MDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPG
530 540 550 560 570 580
400 410 420 430 440 450
pF1KE5 TVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTDIAS
::: :: : .. :. .: :. : :.. : .:. ...: . .:: ::.:.
NP_065 RSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAA
590 600 610 620 630 640
460 470 480 490 500 510
pF1KE5 RGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVSLVQKIELA
:::: :. :..:. : : . :.::.::..:. .: : . .. : :: .:: .
NP_065 RGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNE--GLSLMLIG-PEDVINFKKIYKT
650 660 670 680 690 700
520 530 540
pF1KE5 ARRRRSLPGLASSVKEPLPQAT
.. ...:
NP_065 LKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEE
710 720 730 740 750 760
>>XP_016879601 (OMIM: 613369) PREDICTED: ATP-dependent R (775 aa)
initn: 416 init1: 140 opt: 354 Z-score: 355.2 bits: 76.0 E(85289): 4.8e-13
Smith-Waterman score: 519; 30.0% identity (60.2% similar) in 397 aa overlap (127-518:91-457)
100 110 120 130 140 150
pF1KE5 WKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS
::: .:.. ...: .... : .::: .:
XP_016 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKS--EYTQPTPIQC
70 80 90 100 110
160 170 180 190 200 210
pF1KE5 STIPSLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELA
. .: : :: .. :.:::::: ... :.: ... : :. : .: .... :.:::
XP_016 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELE--PGDGPIAVIVCPTRELC
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE5 QQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLIS
::..: . .:.. .: . :: .: . : : .:...: ::: : .:.. .
XP_016 QQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL--QEGAEIVVCTPGRLIDHVKKKATN
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE5 LEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEG
:...:.::.:::: ..: .: : : ::. : : .: .::: .
XP_016 LQRVSYLVFDEADRMFDMGFEYQVRSI--ASHV-----------RPDRQTLLFSATFRKK
240 250 260 270 280
340 350 360 370 380 390
pF1KE5 VGQLLNKVASPDAVTTITSSKLHCIMPHVKQTFLRLK-GADKVAELVHILKHRDRAERTG
. .: . : . .... . : : :. : .: :. : .: :.
XP_016 IEKLARDILI-DPIR-VVQGDIGEANEDVTQIVEILHSGPSKWNWLT-----RRLVEFTS
290 300 310 320 330
400 410 420 430 440 450
pF1KE5 PSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTD
::.::.: ....... :. : .. . :.:.: : ....:.:.. .:. ::
XP_016 -SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE5 IASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVS----L
.:.:::: ... :.::: .. . :: ::.::.: . :.. ...: : : . :
XP_016 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEK--GVAYTLLT-PKDSNFAGDL
400 410 420 430 440 450
520 530 540
pF1KE5 VQKIELAARRRRSLPGLASSVKEPLPQAT
:...: :
XP_016 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR
460 470 480 490 500 510
>>XP_006721720 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa)
initn: 416 init1: 140 opt: 354 Z-score: 354.1 bits: 76.0 E(85289): 5.5e-13
Smith-Waterman score: 519; 30.0% identity (60.2% similar) in 397 aa overlap (127-518:254-620)
100 110 120 130 140 150
pF1KE5 WKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS
::: .:.. ...: .... : .::: .:
XP_006 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKS--EYTQPTPIQC
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE5 STIPSLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELA
. .: : :: .. :.:::::: ... :.: ... : :. : .: .... :.:::
XP_006 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELE--PGDGPIAVIVCPTRELC
290 300 310 320 330
220 230 240 250 260 270
pF1KE5 QQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLIS
::..: . .:.. .: . :: .: . : : .:...: ::: : .:.. .
XP_006 QQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL--QEGAEIVVCTPGRLIDHVKKKATN
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE5 LEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEG
:...:.::.:::: ..: .: : : ::. : : .: .::: .
XP_006 LQRVSYLVFDEADRMFDMGFEYQVRSI--ASHV-----------RPDRQTLLFSATFRKK
400 410 420 430 440
340 350 360 370 380 390
pF1KE5 VGQLLNKVASPDAVTTITSSKLHCIMPHVKQTFLRLK-GADKVAELVHILKHRDRAERTG
. .: . : . .... . : : :. : .: :. : .: :.
XP_006 IEKLARDILI-DPIR-VVQGDIGEANEDVTQIVEILHSGPSKWNWLT-----RRLVEFTS
450 460 470 480 490
400 410 420 430 440 450
pF1KE5 PSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTD
::.::.: ....... :. : .. . :.:.: : ....:.:.. .:. ::
XP_006 -SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE5 IASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVS----L
.:.:::: ... :.::: .. . :: ::.::.: . :.. ...: : : . :
XP_006 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEK--GVAYTLLT-PKDSNFAGDL
560 570 580 590 600 610
520 530 540
pF1KE5 VQKIELAARRRRSLPGLASSVKEPLPQAT
:...: :
XP_006 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR
620 630 640 650 660 670
>>NP_031398 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa)
initn: 416 init1: 140 opt: 354 Z-score: 354.1 bits: 76.0 E(85289): 5.5e-13
Smith-Waterman score: 519; 30.0% identity (60.2% similar) in 397 aa overlap (127-518:254-620)
100 110 120 130 140 150
pF1KE5 WKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS
::: .:.. ...: .... : .::: .:
NP_031 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKS--EYTQPTPIQC
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE5 STIPSLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELA
. .: : :: .. :.:::::: ... :.: ... : :. : .: .... :.:::
NP_031 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELE--PGDGPIAVIVCPTRELC
290 300 310 320 330
220 230 240 250 260 270
pF1KE5 QQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLIS
::..: . .:.. .: . :: .: . : : .:...: ::: : .:.. .
NP_031 QQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL--QEGAEIVVCTPGRLIDHVKKKATN
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE5 LEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEG
:...:.::.:::: ..: .: : : ::. : : .: .::: .
NP_031 LQRVSYLVFDEADRMFDMGFEYQVRSI--ASHV-----------RPDRQTLLFSATFRKK
400 410 420 430 440
340 350 360 370 380 390
pF1KE5 VGQLLNKVASPDAVTTITSSKLHCIMPHVKQTFLRLK-GADKVAELVHILKHRDRAERTG
. .: . : . .... . : : :. : .: :. : .: :.
NP_031 IEKLARDILI-DPIR-VVQGDIGEANEDVTQIVEILHSGPSKWNWLT-----RRLVEFTS
450 460 470 480 490
400 410 420 430 440 450
pF1KE5 PSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTD
::.::.: ....... :. : .. . :.:.: : ....:.:.. .:. ::
NP_031 -SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE5 IASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVS----L
.:.:::: ... :.::: .. . :: ::.::.: . :.. ...: : : . :
NP_031 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEK--GVAYTLLT-PKDSNFAGDL
560 570 580 590 600 610
520 530 540
pF1KE5 VQKIELAARRRRSLPGLASSVKEPLPQAT
:...: :
NP_031 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR
620 630 640 650 660 670
>>XP_016879600 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa)
initn: 416 init1: 140 opt: 354 Z-score: 354.1 bits: 76.0 E(85289): 5.5e-13
Smith-Waterman score: 519; 30.0% identity (60.2% similar) in 397 aa overlap (127-518:254-620)
100 110 120 130 140 150
pF1KE5 WKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS
::: .:.. ...: .... : .::: .:
XP_016 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKS--EYTQPTPIQC
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE5 STIPSLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELA
. .: : :: .. :.:::::: ... :.: ... : :. : .: .... :.:::
XP_016 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELE--PGDGPIAVIVCPTRELC
290 300 310 320 330
220 230 240 250 260 270
pF1KE5 QQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLIS
::..: . .:.. .: . :: .: . : : .:...: ::: : .:.. .
XP_016 QQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL--QEGAEIVVCTPGRLIDHVKKKATN
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE5 LEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEG
:...:.::.:::: ..: .: : : ::. : : .: .::: .
XP_016 LQRVSYLVFDEADRMFDMGFEYQVRSI--ASHV-----------RPDRQTLLFSATFRKK
400 410 420 430 440
340 350 360 370 380 390
pF1KE5 VGQLLNKVASPDAVTTITSSKLHCIMPHVKQTFLRLK-GADKVAELVHILKHRDRAERTG
. .: . : . .... . : : :. : .: :. : .: :.
XP_016 IEKLARDILI-DPIR-VVQGDIGEANEDVTQIVEILHSGPSKWNWLT-----RRLVEFTS
450 460 470 480 490
400 410 420 430 440 450
pF1KE5 PSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTD
::.::.: ....... :. : .. . :.:.: : ....:.:.. .:. ::
XP_016 -SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE5 IASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVS----L
.:.:::: ... :.::: .. . :: ::.::.: . :.. ...: : : . :
XP_016 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEK--GVAYTLLT-PKDSNFAGDL
560 570 580 590 600 610
520 530 540
pF1KE5 VQKIELAARRRRSLPGLASSVKEPLPQAT
:...: :
XP_016 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR
620 630 640 650 660 670
>>NP_987095 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa)
initn: 416 init1: 140 opt: 354 Z-score: 354.1 bits: 76.0 E(85289): 5.5e-13
Smith-Waterman score: 519; 30.0% identity (60.2% similar) in 397 aa overlap (127-518:254-620)
100 110 120 130 140 150
pF1KE5 WKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS
::: .:.. ...: .... : .::: .:
NP_987 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKS--EYTQPTPIQC
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE5 STIPSLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELA
. .: : :: .. :.:::::: ... :.: ... : :. : .: .... :.:::
NP_987 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELE--PGDGPIAVIVCPTRELC
290 300 310 320 330
220 230 240 250 260 270
pF1KE5 QQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLIS
::..: . .:.. .: . :: .: . : : .:...: ::: : .:.. .
NP_987 QQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL--QEGAEIVVCTPGRLIDHVKKKATN
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE5 LEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEG
:...:.::.:::: ..: .: : : ::. : : .: .::: .
NP_987 LQRVSYLVFDEADRMFDMGFEYQVRSI--ASHV-----------RPDRQTLLFSATFRKK
400 410 420 430 440
340 350 360 370 380 390
pF1KE5 VGQLLNKVASPDAVTTITSSKLHCIMPHVKQTFLRLK-GADKVAELVHILKHRDRAERTG
. .: . : . .... . : : :. : .: :. : .: :.
NP_987 IEKLARDILI-DPIR-VVQGDIGEANEDVTQIVEILHSGPSKWNWLT-----RRLVEFTS
450 460 470 480 490
400 410 420 430 440 450
pF1KE5 PSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTD
::.::.: ....... :. : .. . :.:.: : ....:.:.. .:. ::
NP_987 -SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE5 IASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVS----L
.:.:::: ... :.::: .. . :: ::.::.: . :.. ...: : : . :
NP_987 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEK--GVAYTLLT-PKDSNFAGDL
560 570 580 590 600 610
520 530 540
pF1KE5 VQKIELAARRRRSLPGLASSVKEPLPQAT
:...: :
NP_987 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR
620 630 640 650 660 670
>>NP_057439 (OMIM: 615428) probable ATP-dependent RNA he (455 aa)
initn: 490 init1: 243 opt: 332 Z-score: 336.5 bits: 71.8 E(85289): 5.3e-12
Smith-Waterman score: 627; 34.6% identity (60.8% similar) in 436 aa overlap (102-534:3-395)
80 90 100 110 120 130
pF1KE5 RRPELNQPARLTLGRWERAPLASQGWKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADL
: ..: : .:.: : :.. .: .: ::
NP_057 MAAPEEHDSPTEASQ--PIVEEEETK-TFKDL
10 20
140 150 160 170 180
pF1KE5 GLEPRVLHALQEAAPEV--VQPTTVQSSTIPSLLRGRHVVCAAETGSGKTLSYLLPLLQR
: : .: :: .. ..:: .: .:: :.:: .. :::::::: .. ::.:.
NP_057 G----VTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA
30 40 50 60 70 80
190 200 210 220 230 240
pF1KE5 LLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQ
:: :. : .:::.:.:::: :. . :: :.:. . :: :
NP_057 LLETPQ--RL-----FALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA
90 100 110 120 130
250 260 270 280 290 300
pF1KE5 LSRQPSADVLVATPGALWKALK-SRLISLEQLSFLVLDEADTLLDESFLELVDYILEKSH
:...: ...:::: : :. .. ..:. :..::.:::: .:. .: :: ::.
NP_057 LAKKPH--IIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVI-
140 150 160 170 180 190
310 320 330 340 350 360
pF1KE5 IAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTTITSSKLHCIMPHVKQT
: : . : .::. . : : :...: . : .::: . . ...:
NP_057 ----PRD--------RKTFLFSATMTKKV-QKLQRAALKNPVKCAVSSKYQTV-EKLQQY
200 210 220 230 240
370 380 390 400 410 420
pF1KE5 FLRLKGADKVAELVHILKHRDRAERTGPSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQ
.. . . : . ::.::. : .: : ..::.. .... . .: . . . :.
NP_057 YIFIPSKFKDTYLVYILN-----ELAGNS--FMIFCSTCNNTQRTALLLRNLGFTAIPLH
250 260 270 280 290
430 440 450 460 470 480
pF1KE5 GQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQDYIHRAGRV
::: :.: ...:. ..:.::: ::.:::::: :..:::.:.: .:::::.::.
NP_057 GQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRT
300 310 320 330 340 350
490 500 510 520 530 540
pF1KE5 GRVGSEVPGTVISFVTHPWDVSLVQKIELAARRRRSLPGLASSVKEPLPQAT
.:.: : .:.:::. .:: : :.:: .. :::. .. :
NP_057 ARAGRS--GKAITFVTQ-YDVELFQRIEHLIGKK--LPGFPTQDDEVMMLTERVAEAQRF
360 370 380 390 400
NP_057 ARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
410 420 430 440 450
>>NP_619526 (OMIM: 616533) probable ATP-dependent RNA he (585 aa)
initn: 390 init1: 135 opt: 327 Z-score: 330.1 bits: 70.9 E(85289): 1.2e-11
Smith-Waterman score: 383; 26.9% identity (55.1% similar) in 479 aa overlap (27-454:122-585)
10 20 30 40 50
pF1KE5 MALTRPVRLFSLVTRLLLAPRRGLTVRSPDEPLPVVRIPVALQRQL----EQRQSR
: : : . : : .:. : ..
NP_619 APGSLLHHASPTQTMAAADGSLFDNPRTFSRRP--PAQASRQAKATKRKYQASSEAPPAK
100 110 120 130 140
60 70 80 90 100
pF1KE5 RRN----LP-RPVLVRPGPLLVSARRPELNQPARLTLGRWERAPLASQGWKSRRARRDHF
::: :: . . :. .. .. .: . ... .: : :. ...
NP_619 RRNETSFLPAKKTSVKETQRTFKGNAQKMFSPKKHSVSTSDRNQEERQCIKTSSLFKNNP
150 160 170 180 190 200
110 120 130 140 150 160
pF1KE5 SIERAQQEAPAVRKLSSK----GSFADLGLEPRVLHALQEAAPEVVQPTTVQSSTIPSLL
.: . .. :.:.... : ..: .:::.:... ... . .. . :.::...:: ::
NP_619 DIPELHR--PVVKQVQEKVFTSAAFHELGLHPHLISTINTVL-KMSSMTSVQKQSIPVLL
210 220 230 240 250 260
170 180 190 200 210 220
pF1KE5 RGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVA
.:: .. ..:::::::.: .:..: : .. : . .: .:::::.:::: : ..
NP_619 EGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS-DGPYALVLVPTRELALQSFDTV
270 280 290 300 310 320
230 240 250 260 270 280
pF1KE5 QPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKS-RLISLEQLSF
: : . . .: . : : .: . . . ..:..::: : .:: . : . .: .
NP_619 QKLLKPFTWIVPGVLMG-GEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRW
330 340 350 360 370 380
290 300 310
pF1KE5 LVLDEADTLLDESFLELVDYILE--------------KSHIAEGP---AD--LEDP----
::.:::: .:: .: . . ::. .. ..:: :: :.::
NP_619 LVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSIS
390 400 410 420 430 440
320 330 340 350 360
pF1KE5 --------FNPKAQLVLVGATFPEGVGQLLNKVASPDAV---TTITSSKLH--CIMPHVK
.::: . : . : .:. :.. : :... .:.. :::. :. .
NP_619 VLDKSHDQLNPKDKAV--QEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFIL
450 460 470 480 490 500
370 380 390 400 410 420
pF1KE5 QTFLRLKGADKVAELVHILKHRDRAERTGPSGTVLVFCNSSSTVNWLGYILD-DHKIQHL
: . : .. ..: ... . .: . : ::: . : . . . ... :
NP_619 Q---KCK-FEEDQKMVVFFSSCELVEFH--YSLFLQTLLSSSGAPASGQLPSASMRLKFL
510 520 530 540 550
430 440 450 460 470 480
pF1KE5 RLQGQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQDYIHRA
::.: : :...:: :..: : .::::
NP_619 RLHGGMEQEERTAVFQEFSHSRRGVLLCT
560 570 580
540 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:17:02 2016 done: Tue Nov 8 04:17:04 2016
Total Scan time: 9.120 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]