Result of FASTA (ccds) for
pFN21AE5651
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5651, 523 aa
1>>>pF1KE5651 523 - 523 aa - 523 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4215+/-0.000817; mu= 10.6120+/- 0.049
mean_var=158.5223+/-31.828, 0's: 0 Z-trim(112.8): 11 B-trim: 9 in 1/50
Lambda= 0.101866
statistics sampled from 13490 (13501) to 13490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.415), width: 16
Scan time: 3.440
The best scores are: opt bits E(32554)
CCDS33164.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 523) 3396 510.9 1.5e-144
CCDS46244.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 522) 3379 508.4 8.3e-144
CCDS82432.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 544) 3341 502.8 4.1e-142
CCDS46245.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 543) 3324 500.3 2.3e-141
>>CCDS33164.1 EIF2B4 gene_id:8890|Hs108|chr2 (523 aa)
initn: 3396 init1: 3396 opt: 3396 Z-score: 2708.8 bits: 510.9 E(32554): 1.5e-144
Smith-Waterman score: 3396; 100.0% identity (100.0% similar) in 523 aa overlap (1-523:1-523)
10 20 30 40 50 60
pF1KE5 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
430 440 450 460 470 480
490 500 510 520
pF1KE5 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
:::::::::::::::::::::::::::::::::::::::::::
CCDS33 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
490 500 510 520
>>CCDS46244.1 EIF2B4 gene_id:8890|Hs108|chr2 (522 aa)
initn: 2979 init1: 2979 opt: 3379 Z-score: 2695.3 bits: 508.4 E(32554): 8.3e-144
Smith-Waterman score: 3379; 99.8% identity (99.8% similar) in 523 aa overlap (1-523:1-522)
10 20 30 40 50 60
pF1KE5 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GSAVSAAQCQ-GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE5 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
420 430 440 450 460 470
490 500 510 520
pF1KE5 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
:::::::::::::::::::::::::::::::::::::::::::
CCDS46 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
480 490 500 510 520
>>CCDS82432.1 EIF2B4 gene_id:8890|Hs108|chr2 (544 aa)
initn: 3341 init1: 3341 opt: 3341 Z-score: 2664.9 bits: 502.8 E(32554): 4.1e-142
Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 513 aa overlap (11-523:32-544)
10 20 30 40
pF1KE5 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLR
::::::::::::::::::::::::::::::
CCDS82 PTQQPAAPSTRAPKPSRSLSGSLCALFSDADSGSGMKAELPPGPGAVGREMTKEEKLQLR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 KEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAEL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 RAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 KPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 GSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 NKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 NKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 LVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSK
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE5 VLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE5 DDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKS
490 500 510 520 530 540
pF1KE5 SDQ
:::
CCDS82 SDQ
>>CCDS46245.1 EIF2B4 gene_id:8890|Hs108|chr2 (543 aa)
initn: 2979 init1: 2979 opt: 3324 Z-score: 2651.4 bits: 500.3 E(32554): 2.3e-141
Smith-Waterman score: 3324; 99.8% identity (99.8% similar) in 513 aa overlap (11-523:32-543)
10 20 30 40
pF1KE5 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLR
::::::::::::::::::::::::::::::
CCDS46 PTQQPAAPSTRAPKPSRSLSGSLCALFSDADSGSGMKAELPPGPGAVGREMTKEEKLQLR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 KEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAEL
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
CCDS46 KEKKQQKKKRKEEKGAEPETGSAVSAAQCQ-GPTRELPESGIQLGTPREKVPAGRSKAEL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 RAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 KPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 GSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 NKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 LVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSK
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE5 VLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE5 DDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 DDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKS
490 500 510 520 530 540
pF1KE5 SDQ
:::
CCDS46 SDQ
523 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:33:59 2016 done: Tue Nov 8 05:34:00 2016
Total Scan time: 3.440 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]