Result of FASTA (omim) for
pFN21AE5631
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5631, 477 aa
1>>>pF1KE5631 477 - 477 aa - 477 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1950+/-0.000349; mu= 18.8114+/- 0.022
mean_var=68.7726+/-14.077, 0's: 0 Z-trim(115.0): 28 B-trim: 977 in 2/57
Lambda= 0.154656
statistics sampled from 25090 (25117) to 25090 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.294), width: 16
Scan time: 6.880
The best scores are: opt bits E(85289)
NP_892026 (OMIM: 607975) oxidative stress-induced ( 477) 3232 730.2 3e-210
XP_011515590 (OMIM: 604598) PREDICTED: oxidative s ( 372) 824 192.8 1.4e-48
XP_011515589 (OMIM: 604598) PREDICTED: oxidative s ( 505) 782 183.5 1.2e-45
NP_004328 (OMIM: 604598) oxidative stress-induced ( 505) 782 183.5 1.2e-45
NP_001119583 (OMIM: 604598) oxidative stress-induc ( 549) 782 183.6 1.2e-45
>>NP_892026 (OMIM: 607975) oxidative stress-induced grow (477 aa)
initn: 3232 init1: 3232 opt: 3232 Z-score: 3895.5 bits: 730.2 E(85289): 3e-210
Smith-Waterman score: 3232; 100.0% identity (100.0% similar) in 477 aa overlap (1-477:1-477)
10 20 30 40 50 60
pF1KE5 MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 PGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 PGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 VLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQDSSPLFQVSGFLTRNQAQQPFSLWAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 DYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQDSSPLFQVSGFLTRNQAQQPFSLWAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 NVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 NVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 VLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 LPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPL
370 380 390 400 410 420
430 440 450 460 470
pF1KE5 SAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKPP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 SAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKPP
430 440 450 460 470
>>XP_011515590 (OMIM: 604598) PREDICTED: oxidative stres (372 aa)
initn: 987 init1: 455 opt: 824 Z-score: 993.4 bits: 192.8 E(85289): 1.4e-48
Smith-Waterman score: 1014; 45.7% identity (70.2% similar) in 359 aa overlap (134-475:1-359)
110 120 130 140 150 160
pF1KE5 KSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRR
.::::. .: :.:: :: :. :::...:::
XP_011 MEGSMLTISFGSWMELPGLKFKDWVSSKRR
10 20 30
170 180 190 200 210 220
pF1KE5 GLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQD---SSPLF
.:...:. .::.::. :: :: .:: .. .:.: : .. :: :. .
XP_011 SLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHL
40 50 60 70 80 90
230 240 250 260
pF1KE5 QV--SGFLTRNQ-----------AQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHH
:. :.:. :: .. :: :.:.::.:::::.::::.: : :: .::. :
XP_011 QIEKSNFIKRNWEIRGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFH
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE5 ELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFN
. . :: : . :::::.:.::.:::::: : . ::::::.::: : ::.:.:.
XP_011 SMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFK
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE5 QLPKMLYPEYHKVHQMMREQSILSPSPY-EGYRSLPRHQLLCFKEDCQAVFQDLEGVEKV
:::: ::::::::..:: :: : : :.:.:..: :: : . :.:.. :..:.
XP_011 QLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKI
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE5 FGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMG
: .: ..:::::::.:::: : .. .::.. : ::...: .::. .. .:.:.:
XP_011 FKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALG
280 290 300 310 320 330
450 460 470
pF1KE5 PLAGDNFVRFVQGGALAVASSLLRKETRKPP
::.:::::::..::::.:. : .. .:
XP_011 PLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDGIA
340 350 360 370
>>XP_011515589 (OMIM: 604598) PREDICTED: oxidative stres (505 aa)
initn: 1545 init1: 769 opt: 782 Z-score: 940.8 bits: 183.5 E(85289): 1.2e-45
Smith-Waterman score: 1572; 50.6% identity (74.4% similar) in 480 aa overlap (13-475:13-492)
10 20 30 40 50 60
pF1KE5 MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEA
:: .::.:.:::::::::::.:::: :: . .::::. .:. :: ::
XP_011 MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 PGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHV
.::.::::.::::::::::..:::.:::.::.::.::: .. ::: :: ...: ::::
XP_011 RHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYR
:::.. ::::::..::::. .: :.:: :: :. :::...:::.:...:. .::.::.
XP_011 VLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYK
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 DYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQD---SSPLFQV--SGFLTRNQ-----
:: :: .:: .. .:.: : .. :: :. .:. :.:. ::
XP_011 HYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGY
190 200 210 220 230 240
240 250 260 270 280
pF1KE5 ------AQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPA
.. :: :.:.::.:::::.::::.: : :: .::. : . . :: : .
XP_011 QRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 SDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMM
:::::.:.::.:::::: : . ::::::.::: : ::.:.:.:::: ::::::::..::
XP_011 VDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMM
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 REQSILSPSPY-EGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLS
:: : : :.:.:..: :: : . :.:.. :..:.: .: ..:::::::.::
XP_011 CTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE5 FLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALA
:: : .. .::.. : ::...: .::. .. .:.:.:::.:::::::..::::.
XP_011 FLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALG
430 440 450 460 470 480
470
pF1KE5 VASSLLRKETRKPP
:. : .. .:
XP_011 VTRCLATRQKKKHLFVERGGGDGIA
490 500
>>NP_004328 (OMIM: 604598) oxidative stress-induced grow (505 aa)
initn: 1545 init1: 769 opt: 782 Z-score: 940.8 bits: 183.5 E(85289): 1.2e-45
Smith-Waterman score: 1572; 50.6% identity (74.4% similar) in 480 aa overlap (13-475:13-492)
10 20 30 40 50 60
pF1KE5 MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEA
:: .::.:.:::::::::::.:::: :: . .::::. .:. :: ::
NP_004 MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 PGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHV
.::.::::.::::::::::..:::.:::.::.::.::: .. ::: :: ...: ::::
NP_004 RHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYR
:::.. ::::::..::::. .: :.:: :: :. :::...:::.:...:. .::.::.
NP_004 VLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYK
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 DYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQD---SSPLFQV--SGFLTRNQ-----
:: :: .:: .. .:.: : .. :: :. .:. :.:. ::
NP_004 HYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGY
190 200 210 220 230 240
240 250 260 270 280
pF1KE5 ------AQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPA
.. :: :.:.::.:::::.::::.: : :: .::. : . . :: : .
NP_004 QRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 SDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMM
:::::.:.::.:::::: : . ::::::.::: : ::.:.:.:::: ::::::::..::
NP_004 VDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMM
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 REQSILSPSPY-EGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLS
:: : : :.:.:..: :: : . :.:.. :..:.: .: ..:::::::.::
NP_004 CTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE5 FLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALA
:: : .. .::.. : ::...: .::. .. .:.:.:::.:::::::..::::.
NP_004 FLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALG
430 440 450 460 470 480
470
pF1KE5 VASSLLRKETRKPP
:. : .. .:
NP_004 VTRCLATRQKKKHLFVERGGGDGIA
490 500
>>NP_001119583 (OMIM: 604598) oxidative stress-induced g (549 aa)
initn: 1545 init1: 769 opt: 782 Z-score: 940.3 bits: 183.6 E(85289): 1.2e-45
Smith-Waterman score: 1572; 50.6% identity (74.4% similar) in 480 aa overlap (13-475:57-536)
10 20 30 40
pF1KE5 MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYT
:: .::.:.:::::::::::.:::: ::
NP_001 FNSLVQYFGDNLGRKVKAMPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYL
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE5 KPDAIHPHPLLQRKLTEAPGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGN
. .::::. .:. :: :: .::.::::.::::::::::..:::.:::.::.::.::: .
NP_001 SSEAIHPNTILNSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYD
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE5 MKSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKR
. ::: :: ...: :::::::.. ::::::..::::. .: :.:: :: :. :::...::
NP_001 YPSVLHWKLEQHHYIPHVVLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKR
150 160 170 180 190 200
170 180 190 200 210
pF1KE5 RGLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQD---SSPL
:.:...:. .::.::. :: :: .:: .. .:.: : .. :: :.
NP_001 RSLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKH
210 220 230 240 250 260
220 230 240 250 260
pF1KE5 FQV--SGFLTRNQ-----------AQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIH
.:. :.:. :: .. :: :.:.::.:::::.::::.: : :: .::.
NP_001 LQIEKSNFIKRNWEIRGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVF
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE5 HELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVF
: . . :: : . :::::.:.::.:::::: : . ::::::.::: : ::.:.:
NP_001 HSMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIF
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE5 NQLPKMLYPEYHKVHQMMREQSILSPSPY-EGYRSLPRHQLLCFKEDCQAVFQDLEGVEK
.:::: ::::::::..:: :: : : :.:.:..: :: : . :.:.. :..:
NP_001 KQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKK
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE5 VFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAM
.: .: ..:::::::.:::: : .. .::.. : ::...: .::. .. .:.:.
NP_001 IFKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFAL
450 460 470 480 490 500
450 460 470
pF1KE5 GPLAGDNFVRFVQGGALAVASSLLRKETRKPP
:::.:::::::..::::.:. : .. .:
NP_001 GPLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDGIA
510 520 530 540
477 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:21:24 2016 done: Tue Nov 8 05:21:25 2016
Total Scan time: 6.880 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]