Result of FASTA (omim) for
pFN21AE5623
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5623, 474 aa
1>>>pF1KE5623 474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0163+/-0.000443; mu= 21.1241+/- 0.028
mean_var=147.5643+/-39.215, 0's: 0 Z-trim(112.6): 219 B-trim: 2314 in 2/53
Lambda= 0.105580
statistics sampled from 21284 (21651) to 21284 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.254), width: 16
Scan time: 7.230
The best scores are: opt bits E(85289)
XP_016858811 (OMIM: 608888) PREDICTED: RNA-binding ( 474) 3156 493.4 5.7e-139
NP_694453 (OMIM: 608888) RNA-binding protein 45 [H ( 474) 3156 493.4 5.7e-139
XP_005246344 (OMIM: 608888) PREDICTED: RNA-binding ( 476) 3142 491.3 2.5e-138
XP_016858809 (OMIM: 608888) PREDICTED: RNA-binding ( 617) 2480 390.6 6.5e-108
XP_016858810 (OMIM: 608888) PREDICTED: RNA-binding ( 617) 2480 390.6 6.5e-108
XP_016881329 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 496) 306 59.3 2.8e-08
NP_001020259 (OMIM: 612679) CUGBP Elav-like family ( 484) 291 57.0 1.4e-07
NP_001020258 (OMIM: 612679) CUGBP Elav-like family ( 485) 288 56.5 1.9e-07
NP_001278035 (OMIM: 612678) CUGBP Elav-like family ( 464) 284 55.9 2.8e-07
XP_016881330 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 485) 284 55.9 2.8e-07
NP_064565 (OMIM: 612679) CUGBP Elav-like family me ( 486) 281 55.5 3.9e-07
XP_016881334 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 483) 276 54.7 6.6e-07
NP_001317532 (OMIM: 612679) CUGBP Elav-like family ( 484) 276 54.7 6.6e-07
XP_011524394 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 457) 274 54.4 7.9e-07
XP_016881333 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 484) 273 54.3 9.1e-07
XP_016881331 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 485) 273 54.3 9.1e-07
XP_016881348 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 455) 272 54.1 9.8e-07
XP_016881347 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 456) 272 54.1 9.8e-07
XP_016881344 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 456) 272 54.1 9.8e-07
XP_011507413 (OMIM: 612678) PREDICTED: CUGBP Elav- ( 414) 271 53.8 1e-06
NP_001166120 (OMIM: 612678) CUGBP Elav-like family ( 415) 271 53.9 1e-06
XP_011524393 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 458) 271 53.9 1.1e-06
NP_009116 (OMIM: 612678) CUGBP Elav-like family me ( 465) 271 53.9 1.1e-06
XP_016881354 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 446) 270 53.7 1.2e-06
XP_016881350 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 447) 270 53.7 1.2e-06
XP_016881351 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 447) 270 53.7 1.2e-06
NP_001020260 (OMIM: 612679) CUGBP Elav-like family ( 448) 270 53.8 1.2e-06
XP_016881341 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 474) 270 53.8 1.2e-06
XP_016881339 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 475) 270 53.8 1.2e-06
XP_016881335 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 476) 270 53.8 1.2e-06
XP_011524389 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 494) 270 53.8 1.3e-06
XP_016881345 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 456) 269 53.6 1.3e-06
XP_016881343 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 457) 269 53.6 1.3e-06
XP_016881342 (OMIM: 612679) PREDICTED: CUGBP Elav- ( 457) 269 53.6 1.3e-06
NP_001166155 (OMIM: 612681) CUGBP Elav-like family ( 454) 256 51.6 5.3e-06
NP_443072 (OMIM: 612681) CUGBP Elav-like family me ( 481) 256 51.7 5.4e-06
NP_001166144 (OMIM: 612680) CUGBP Elav-like family ( 409) 253 51.1 6.9e-06
XP_006722895 (OMIM: 612680) PREDICTED: CUGBP Elav- ( 485) 253 51.2 7.5e-06
NP_068757 (OMIM: 612680) CUGBP Elav-like family me ( 485) 253 51.2 7.5e-06
XP_016872622 (OMIM: 601074) PREDICTED: CUGBP Elav- ( 483) 252 51.1 8.3e-06
XP_016872623 (OMIM: 601074) PREDICTED: CUGBP Elav- ( 483) 252 51.1 8.3e-06
NP_941989 (OMIM: 601074) CUGBP Elav-like family me ( 483) 252 51.1 8.3e-06
XP_011518161 (OMIM: 601074) PREDICTED: CUGBP Elav- ( 483) 252 51.1 8.3e-06
XP_006722896 (OMIM: 612680) PREDICTED: CUGBP Elav- ( 484) 251 50.9 9.3e-06
XP_016868729 (OMIM: 604819,615583) PREDICTED: poly ( 499) 236 48.6 4.6e-05
NP_001258029 (OMIM: 604819,615583) poly(U)-binding ( 499) 236 48.6 4.6e-05
NP_001258026 (OMIM: 604819,615583) poly(U)-binding ( 513) 236 48.7 4.6e-05
XP_016868728 (OMIM: 604819,615583) PREDICTED: poly ( 516) 236 48.7 4.7e-05
NP_001129505 (OMIM: 604819,615583) poly(U)-binding ( 516) 236 48.7 4.7e-05
NP_001258028 (OMIM: 604819,615583) poly(U)-binding ( 530) 236 48.7 4.7e-05
>>XP_016858811 (OMIM: 608888) PREDICTED: RNA-binding pro (474 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 2615.9 bits: 493.4 E(85289): 5.7e-139
Smith-Waterman score: 3156; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE5 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 KYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVY
370 380 390 400 410 420
430 440 450 460 470
pF1KE5 LVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
430 440 450 460 470
>>NP_694453 (OMIM: 608888) RNA-binding protein 45 [Homo (474 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 2615.9 bits: 493.4 E(85289): 5.7e-139
Smith-Waterman score: 3156; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE5 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 QEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 KYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 KYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 SSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVY
370 380 390 400 410 420
430 440 450 460 470
pF1KE5 LVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 LVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
430 440 450 460 470
>>XP_005246344 (OMIM: 608888) PREDICTED: RNA-binding pro (476 aa)
initn: 3142 init1: 1659 opt: 3142 Z-score: 2604.4 bits: 491.3 E(85289): 2.5e-138
Smith-Waterman score: 3142; 99.6% identity (99.6% similar) in 476 aa overlap (1-474:1-476)
10 20 30 40 50 60
pF1KE5 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPF--EQQSEFSSFDKNDS
:::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_005 CDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFVGEQQSEFSSFDKNDS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 RGQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 YAKYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YAKYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQF
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 GGSSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGSSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 VYLVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYLVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
430 440 450 460 470
>>XP_016858809 (OMIM: 608888) PREDICTED: RNA-binding pro (617 aa)
initn: 2474 init1: 2474 opt: 2480 Z-score: 2058.3 bits: 390.6 E(85289): 6.5e-108
Smith-Waterman score: 2480; 99.0% identity (99.5% similar) in 381 aa overlap (94-474:238-617)
70 80 90 100 110 120
pF1KE5 ESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRI
:.: : .:::::::::::::::::::::::
XP_016 FTAKLVLAYFEYFSDLPLSDAQISIYKKRKNSTFP-QVFIAQSRSSGSHRDVEDEELTRI
210 220 230 240 250 260
130 140 150 160 170 180
pF1KE5 FVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDR
270 280 290 300 310 320
190 200 210 220 230 240
pF1KE5 SFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRGQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRGQEA
330 340 350 360 370 380
250 260 270 280 290 300
pF1KE5 ISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYK
390 400 410 420 430 440
310 320 330 340 350 360
pF1KE5 LHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGGSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGGSSG
450 460 470 480 490 500
370 380 390 400 410 420
pF1KE5 SQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVS
510 520 530 540 550 560
430 440 450 460 470
pF1KE5 GKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
570 580 590 600 610
>--
initn: 720 init1: 692 opt: 694 Z-score: 588.1 bits: 118.6 E(85289): 5.1e-26
Smith-Waterman score: 694; 83.5% identity (88.2% similar) in 127 aa overlap (1-127:1-124)
10 20 30 40 50 60
pF1KE5 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
::::::::::::::::::::::::::::::::::::::::: . .:: : :
XP_016 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVRVP---GSGCPRGKEWASW
70 80 90 100 110
130 140 150 160 170 180
pF1KE5 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
: . ...
XP_016 TSLHLLLCRGEGGVEHPFPAADQTAPGLGTGAALRRGSPPTKLRRVAGKGTGCGVFAPRE
120 130 140 150 160 170
>>XP_016858810 (OMIM: 608888) PREDICTED: RNA-binding pro (617 aa)
initn: 2474 init1: 2474 opt: 2480 Z-score: 2058.3 bits: 390.6 E(85289): 6.5e-108
Smith-Waterman score: 2480; 99.0% identity (99.5% similar) in 381 aa overlap (94-474:238-617)
70 80 90 100 110 120
pF1KE5 ESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRI
:.: : .:::::::::::::::::::::::
XP_016 FTAKLVLAYFEYFSDLPLSDAQISIYKKRKNSTFP-QVFIAQSRSSGSHRDVEDEELTRI
210 220 230 240 250 260
130 140 150 160 170 180
pF1KE5 FVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDR
270 280 290 300 310 320
190 200 210 220 230 240
pF1KE5 SFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRGQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFEQQSEFSSFDKNDSRGQEA
330 340 350 360 370 380
250 260 270 280 290 300
pF1KE5 ISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYK
390 400 410 420 430 440
310 320 330 340 350 360
pF1KE5 LHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGGSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGGSSG
450 460 470 480 490 500
370 380 390 400 410 420
pF1KE5 SQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVS
510 520 530 540 550 560
430 440 450 460 470
pF1KE5 GKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
570 580 590 600 610
>--
initn: 720 init1: 692 opt: 694 Z-score: 588.1 bits: 118.6 E(85289): 5.1e-26
Smith-Waterman score: 694; 83.5% identity (88.2% similar) in 127 aa overlap (1-127:1-124)
10 20 30 40 50 60
pF1KE5 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEEL
::::::::::::::::::::::::::::::::::::::::: . .:: : :
XP_016 HTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVRVP---GSGCPRGKEWASW
70 80 90 100 110
130 140 150 160 170 180
pF1KE5 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIEN
: . ...
XP_016 TSLHLLLCRGEGGVEHPFPAADQTAPGLGTGAALRRGSPPTKLRRVAGKGTGCGVFAPRE
120 130 140 150 160 170
>>XP_016881329 (OMIM: 612679) PREDICTED: CUGBP Elav-like (496 aa)
initn: 191 init1: 114 opt: 306 Z-score: 269.6 bits: 59.3 E(85289): 2.8e-08
Smith-Waterman score: 336; 23.8% identity (53.5% similar) in 501 aa overlap (2-465:14-491)
10 20 30
pF1KE5 MDEAGSSASGGGFRPG----VDSLDEPPNS------------RIFL-V
:.:. :..: : :: ...:.. :.. ..:.
XP_016 MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 ISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCL
: . :. :. : :: : .. :..:. : :: ::. . . .: .:. .: :
XP_016 IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 GPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFV-MIPKSYTEEDLREKFKVYGDIEYCS
:. ..::.: :.:.: : ::..: :: :. :. .:.:.:. :...:.:: :.
XP_016 LPGMNRPIQVKPADSESRG-----EDRKL---FVGMLNKQQSEDDVRRLFEAFGNIEECT
130 140 150 160 170
160 170 180 190 200
pF1KE5 IIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRAILAEPKNKASESSEQDYYSNMR-
:... :.::: ..:.: . ..: :: : .. ... . .. . . .. : .::
XP_016 ILRGP-DGNSKGCAFVKYSSHAEAQAAI-NALHGSQTMPGASSSLVVKFADTDKERTMRR
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE5 -QEALGHEPRVN--MFPFEQQSEFS-SFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSIF
:. :. : .:: . .. .. .... . .... . . :. :. ..
XP_016 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE5 DI-VPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQ-YPPGNRIGVSFIDDG
. . :: . .. :.. .. .: . ..:: :: .:
XP_016 ALNMNGLAAAPMTPTSGGSTPPGITA--PAVPSIPSPIGVNGFTGLPPQA--------NG
300 310 320 330 340
330 340 350 360 370 380
pF1KE5 SNATDLLRKMATQMVAAQLASMVWNNPSQQQF---MQFGGSSGSQLPQIQTDVVLPSCKK
. :.. . . . :: : . .: :: . .:..: .. : . ..:.
XP_016 QPAAEAVFANGIHPYPAQ--SPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPP
350 360 370 380 390
390 400 410 420 430
pF1KE5 KAPA---ETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLI--EVYLVSGKN----VGYAK
: : : ::: :. . : ..: :::.: .:.. . : :...
XP_016 MIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFVDRATNQSKCFGFVS
400 410 420 430 440 450
440 450 460 470
pF1KE5 YADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
. . ::. :: ...: .. ::::.: :..
XP_016 FDNPASAQTAIQAMNGFQIGMKRLKVQLK-RPKDANRPY
460 470 480 490
>>NP_001020259 (OMIM: 612679) CUGBP Elav-like family mem (484 aa)
initn: 215 init1: 114 opt: 291 Z-score: 257.3 bits: 57.0 E(85289): 1.4e-07
Smith-Waterman score: 307; 22.9% identity (52.9% similar) in 497 aa overlap (2-465:14-479)
10 20 30
pF1KE5 MDEAGSSASGGGFRPG----VDSLDEPPNS------------RIFL-V
:.:. :..: : :: ...:.. :.. ..:.
NP_001 MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 ISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCL
: . :. :. : :: : .. :..:. : :: ::. . . .: .:. .: :
NP_001 IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
70 80 90 100 110 120
100 110 120 130 140
pF1KE5 GPNDTKPIKVFIAQSRSSGSHRDVEDEELTR-IFV-MIPKSYTEEDLREKFKVYGDIEYC
:. ..::.: :.:.: :. ... : .:: :. :. .:.:.:. :...:.:: :
NP_001 LPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEEC
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE5 SIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRAILAEPKNKASESSEQDYYSNMR
.:... :.::: ..:.: . ..: :: : .. ... . .. . . .. : .::
NP_001 TILRGP-DGNSKGCAFVKYSSHAEAQAAI-NALHGSQTMPGASSSLVVKFADTDKERTMR
190 200 210 220 230
210 220 230 240 250 260
pF1KE5 --QEALGHEPRVN--MFPFEQQSEFSSFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSIF
:. :. : .:: . ... .... . .... . . :. :. ..
NP_001 RMQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE5 DI-VPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQ-YPPGNRIGVSFIDDG
. . :: . .. :.. .. .: . ..:: :: .:
NP_001 ALNMNGLAAAPMTPTSGGSTPPGITA--PAVPSIPSPIGVNGFTGLPPQA--------NG
300 310 320 330 340
330 340 350 360 370 380
pF1KE5 SNATDLLRKMATQMVAAQLASMVWNNPSQQQF---MQFGGSSGSQLPQIQTDVVLPSCKK
. :.. . . . :: : . .: :: . .:..: .. : . ..:.
NP_001 QPAAEAVFANGIHPYPAQ--SPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPP
350 360 370 380 390 400
390 400 410 420 430
pF1KE5 KAPA---ETPVKERLFIVFNPHPLPLDVLEDIFCRFGN--LIEVYLVSGKNVGYAKYADR
: : : ::: . :: . ::. :....: :.... .
NP_001 MIPQQQREGPEGCNLFI----YHLPQE--------FGDAELMQMFL----PFGFVSFDNP
410 420 430 440 450
440 450 460 470
pF1KE5 ISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
::. :: ...: .. ::::.: :..
NP_001 ASAQTAIQAMNGFQIGMKRLKVQLK-RPKDANRPY
460 470 480
>>NP_001020258 (OMIM: 612679) CUGBP Elav-like family mem (485 aa)
initn: 215 init1: 114 opt: 288 Z-score: 254.8 bits: 56.5 E(85289): 1.9e-07
Smith-Waterman score: 304; 22.7% identity (53.0% similar) in 498 aa overlap (2-465:14-480)
10 20 30
pF1KE5 MDEAGSSASGGGFRPG----VDSLDEPPNS------------RIFL-V
:.:. :..: : :: ...:.. :.. ..:.
NP_001 MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 ISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCL
: . :. :. : :: : .. :..:. : :: ::. . . .: .:. .: :
NP_001 IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
70 80 90 100 110 120
100 110 120 130 140
pF1KE5 GPNDTKPIKVFIAQSRSSGSHRDVEDE--ELTRIFV-MIPKSYTEEDLREKFKVYGDIEY
:. ..::.: :.:.: :. ... . ..:: :. :. .:.:.:. :...:.::
NP_001 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE5 CSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRAILAEPKNKASESSEQDYYSNM
:.:... :.::: ..:.: . ..: :: : .. ... . .. . . .. : .:
NP_001 CTILRGP-DGNSKGCAFVKYSSHAEAQAAI-NALHGSQTMPGASSSLVVKFADTDKERTM
190 200 210 220 230
210 220 230 240 250 260
pF1KE5 R--QEALGHEPRVN--MFPFEQQSEFSSFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSI
: :. :. : .:: . ... .... . .... . . :. :. ..
NP_001 RRMQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGGYLNPMAAFAAAQMQQM
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE5 FDI-VPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQ-YPPGNRIGVSFIDD
. . :: . .. :.. .. .: . ..:: :: .
NP_001 AALNMNGLAAAPMTPTSGGSTPPGITA--PAVPSIPSPIGVNGFTGLPPQA--------N
300 310 320 330 340
330 340 350 360 370
pF1KE5 GSNATDLLRKMATQMVAAQLASMVWNNPSQQQF---MQFGGSSGSQLPQIQTDVVLPSCK
:. :.. . . . :: : . .: :: . .:..: .. : . ..:.
NP_001 GQPAAEAVFANGIHPYPAQ--SPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPP
350 360 370 380 390 400
380 390 400 410 420 430
pF1KE5 KKAPA---ETPVKERLFIVFNPHPLPLDVLEDIFCRFGN--LIEVYLVSGKNVGYAKYAD
: : : ::: . :: . ::. :....: :.... .
NP_001 PMIPQQQREGPEGCNLFI----YHLPQE--------FGDAELMQMFL----PFGFVSFDN
410 420 430 440 450
440 450 460 470
pF1KE5 RISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
::. :: ...: .. ::::.: :..
NP_001 PASAQTAIQAMNGFQIGMKRLKVQLK-RPKDANRPY
460 470 480
>>NP_001278035 (OMIM: 612678) CUGBP Elav-like family mem (464 aa)
initn: 176 init1: 117 opt: 284 Z-score: 251.7 bits: 55.9 E(85289): 2.8e-07
Smith-Waterman score: 317; 24.3% identity (53.3% similar) in 478 aa overlap (20-465:1-459)
10 20 30 40 50
pF1KE5 MDEAGSSASGGGFRPGVDSLDEPPNSRIFL-VISKYTPESVLRERFSPFGDIQDIWVVRD
. :: ..:. : .. :. :. : :: : .. :..:
NP_001 MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKD
10 20 30 40
60 70 80 90 100 110
pF1KE5 KHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEE
:.: :: ::. . ..: .:. .: : :. ..::.: :.:.: : ::..
NP_001 KYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRG-----EDRK
50 60 70 80 90
120 130 140 150 160 170
pF1KE5 LTRIFV-MIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAI
: :: :. :. :.::.:. :. .: :. :..... : ::: ..:.. ..: ::
NP_001 L---FVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGP-DGTSKGCAFVKFQTHAEAQAAI
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE5 ENCDRSFRAILAEPKN---KASESSEQDYYSNMRQEALGHEPRVNMF-PFEQQ-SEFSSF
: .: :.. . .. : ... .. :.: : ...:: :. : . .:..
NP_001 -NTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVAT----QLGMFSPIALQFGAYSAY
160 170 180 190 200
240 250 260 270 280
pF1KE5 DKNDSRGQEAI----SKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVV
. . : :. : :: .. . .. : .. .. . :: . : :. . .
NP_001 TQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAIN-ANGLIATPIT--PSSGTSTPPA
210 220 230 240 250 260
290 300 310 320 330
pF1KE5 QYFNVASAIYAKYKLHGFQ----YPPGNRIGVSFIDDG---------SNATDLLRKM--A
. .::: : ..:.. : :. .. .: . .: :.. .
NP_001 IAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAG
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE5 TQMVAAQLASMVWNNPSQQQFMQFGGSSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFI
: .: :.. :. : . ... :: : . . ... : : .::
NP_001 MQHYTAYPAAYSLVAPAFPQPPALVAQQPPPPPQ-QQQQQQQQQQQQQQREGPDGCNIFI
330 340 350 360 370 380
400 410 420 430 440
pF1KE5 VFNPHPLPLDVLEDIFCRFGNLI--EVYLVSGKN----VGYAKYADRISANDAIATLHGK
:. . . . ..: ::..: .:.. . : :.... . ::. :: ...:
NP_001 YHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGF
390 400 410 420 430 440
450 460 470
pF1KE5 ILNGVRLKVMLADSPREESNKRQRTY
.. ::::.: :..
NP_001 QIGMKRLKVQLK-RPKDANRPY
450 460
>>XP_016881330 (OMIM: 612679) PREDICTED: CUGBP Elav-like (485 aa)
initn: 215 init1: 114 opt: 284 Z-score: 251.6 bits: 55.9 E(85289): 2.8e-07
Smith-Waterman score: 300; 22.9% identity (53.0% similar) in 498 aa overlap (2-465:14-480)
10 20 30
pF1KE5 MDEAGSSASGGGFRPG----VDSLDEPPNS------------RIFL-V
:.:. :..: : :: ...:.. :.. ..:.
XP_016 MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 ISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCL
: . :. :. : :: : .. :..:. : :: ::. . . .: .:. .: :
XP_016 IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
70 80 90 100 110 120
100 110 120 130 140
pF1KE5 GPNDTKPIKVFIAQSRSSGSHRDVEDEELTR-IFV-MIPKSYTEEDLREKFKVYGDIEYC
:. ..::.: :.:.: :. ... : .:: :. :. .:.:.:. :...:.:: :
XP_016 LPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEEC
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE5 SIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRAILAEPKNKASESSEQDYYSNMR
.:... :.::: ..:.: . ..: :: : .. ... . .. . . .. : .::
XP_016 TILRGP-DGNSKGCAFVKYSSHAEAQAAI-NALHGSQTMPGASSSLVVKFADTDKERTMR
190 200 210 220 230
210 220 230 240 250 260
pF1KE5 --QEALGHEPRVN--MFPFEQQSEFS-SFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSI
:. :. : .:: . .. .. .... . .... . . :. :. ..
XP_016 RMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQM
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE5 FDI-VPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQ-YPPGNRIGVSFIDD
. . :: . .. :.. .. .: . ..:: :: .
XP_016 AALNMNGLAAAPMTPTSGGSTPPGITA--PAVPSIPSPIGVNGFTGLPPQA--------N
300 310 320 330 340
330 340 350 360 370
pF1KE5 GSNATDLLRKMATQMVAAQLASMVWNNPSQQQF---MQFGGSSGSQLPQIQTDVVLPSCK
:. :.. . . . :: : . .: :: . .:..: .. : . ..:.
XP_016 GQPAAEAVFANGIHPYPAQ--SPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPP
350 360 370 380 390 400
380 390 400 410 420 430
pF1KE5 KKAPA---ETPVKERLFIVFNPHPLPLDVLEDIFCRFGN--LIEVYLVSGKNVGYAKYAD
: : : ::: . :: . ::. :....: :.... .
XP_016 PMIPQQQREGPEGCNLFI----YHLPQE--------FGDAELMQMFL----PFGFVSFDN
410 420 430 440 450
440 450 460 470
pF1KE5 RISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY
::. :: ...: .. ::::.: :..
XP_016 PASAQTAIQAMNGFQIGMKRLKVQLK-RPKDANRPY
460 470 480
474 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:15:59 2016 done: Tue Nov 8 05:16:00 2016
Total Scan time: 7.230 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]