Result of FASTA (omim) for
pFN21AE5609
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5609, 533 aa
1>>>pF1KE5609 533 - 533 aa - 533 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2882+/-0.000549; mu= 13.2277+/- 0.034
mean_var=101.8047+/-20.756, 0's: 0 Z-trim(108.4): 152 B-trim: 191 in 1/50
Lambda= 0.127113
statistics sampled from 16359 (16538) to 16359 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.524), E-opt: 0.2 (0.194), width: 16
Scan time: 8.240
The best scores are: opt bits E(85289)
NP_954868 (OMIM: 604336) putative tyrosine-protein ( 533) 3485 650.7 3.1e-186
NP_954870 (OMIM: 604336) putative tyrosine-protein ( 551) 3333 622.9 7.8e-178
NP_954869 (OMIM: 604336) putative tyrosine-protein ( 513) 3139 587.3 3.8e-167
NP_954863 (OMIM: 606791) phosphatidylinositol 3,4, ( 522) 2920 547.1 4.7e-155
NP_001277153 (OMIM: 604336) putative tyrosine-prot ( 413) 2744 514.8 2e-145
NP_570141 (OMIM: 606791) phosphatidylinositol 3,4, ( 445) 2066 390.5 5.8e-108
NP_001135440 (OMIM: 606791) phosphatidylinositol 3 ( 411) 2058 389.0 1.5e-107
NP_001258779 (OMIM: 606791) phosphatidylinositol 3 ( 193) 1041 202.3 1.1e-51
NP_001291646 (OMIM: 153480,155600,158350,176807,18 ( 576) 633 127.8 9.1e-29
NP_000305 (OMIM: 153480,155600,158350,176807,18847 ( 403) 616 124.5 5.9e-28
NP_001294952 (OMIM: 600076) tensin-1 isoform 3 [Ho (1714) 429 90.7 4e-17
XP_011510025 (OMIM: 600076) PREDICTED: tensin-1 is (1714) 429 90.7 4e-17
NP_001294951 (OMIM: 600076) tensin-1 isoform 2 [Ho (1721) 429 90.7 4e-17
XP_016860297 (OMIM: 600076) PREDICTED: tensin-1 is (1727) 429 90.7 4e-17
NP_072174 (OMIM: 600076) tensin-1 isoform 1 [Homo (1735) 429 90.7 4e-17
XP_016860296 (OMIM: 600076) PREDICTED: tensin-1 is (1802) 429 90.7 4.1e-17
XP_016860300 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 429 90.7 4.2e-17
XP_016860301 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 429 90.7 4.2e-17
XP_016860295 (OMIM: 600076) PREDICTED: tensin-1 is (1815) 429 90.7 4.2e-17
XP_016860294 (OMIM: 600076) PREDICTED: tensin-1 is (1824) 429 90.7 4.2e-17
XP_011510017 (OMIM: 600076) PREDICTED: tensin-1 is (1831) 429 90.7 4.2e-17
XP_011510015 (OMIM: 600076) PREDICTED: tensin-1 is (1839) 429 90.7 4.2e-17
XP_011510014 (OMIM: 600076) PREDICTED: tensin-1 is (1844) 429 90.7 4.2e-17
XP_016860293 (OMIM: 600076) PREDICTED: tensin-1 is (1852) 429 90.7 4.2e-17
XP_016860292 (OMIM: 600076) PREDICTED: tensin-1 is (1867) 429 90.7 4.3e-17
XP_016860291 (OMIM: 600076) PREDICTED: tensin-1 is (1880) 429 90.7 4.3e-17
XP_016860290 (OMIM: 600076) PREDICTED: tensin-1 is (1895) 429 90.7 4.3e-17
XP_016860299 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 429 90.7 4.3e-17
XP_016860298 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 429 90.7 4.3e-17
XP_016868028 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 418 88.6 1.4e-16
XP_011513785 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 418 88.6 1.4e-16
XP_011513784 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 418 88.6 1.4e-16
NP_073585 (OMIM: 606825) tensin-3 [Homo sapiens] (1445) 418 88.6 1.4e-16
XP_011513783 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 418 88.6 1.4e-16
XP_011513782 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 418 88.6 1.4e-16
XP_011513781 (OMIM: 606825) PREDICTED: tensin-3 is (1488) 418 88.6 1.4e-16
XP_011513780 (OMIM: 606825) PREDICTED: tensin-3 is (1534) 418 88.6 1.5e-16
XP_016868026 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 418 88.6 1.5e-16
XP_011513779 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 418 88.6 1.5e-16
XP_016868027 (OMIM: 606825) PREDICTED: tensin-3 is (1559) 418 88.6 1.5e-16
XP_011513778 (OMIM: 606825) PREDICTED: tensin-3 is (1561) 418 88.6 1.5e-16
XP_016863484 (OMIM: 602052) PREDICTED: cyclin-G-as (1131) 393 83.9 2.8e-15
XP_016863483 (OMIM: 602052) PREDICTED: cyclin-G-as (1197) 393 84.0 2.9e-15
XP_016863482 (OMIM: 602052) PREDICTED: cyclin-G-as (1219) 393 84.0 2.9e-15
XP_011511736 (OMIM: 602052) PREDICTED: cyclin-G-as (1219) 393 84.0 2.9e-15
NP_001305063 (OMIM: 602052) cyclin-G-associated ki (1232) 393 84.0 3e-15
XP_005272327 (OMIM: 602052) PREDICTED: cyclin-G-as (1236) 393 84.0 3e-15
XP_016863481 (OMIM: 602052) PREDICTED: cyclin-G-as (1246) 393 84.0 3e-15
XP_011511734 (OMIM: 602052) PREDICTED: cyclin-G-as (1267) 393 84.0 3e-15
XP_011511733 (OMIM: 602052) PREDICTED: cyclin-G-as (1272) 393 84.0 3e-15
>>NP_954868 (OMIM: 604336) putative tyrosine-protein pho (533 aa)
initn: 3485 init1: 3485 opt: 3485 Z-score: 3464.5 bits: 650.7 E(85289): 3.1e-186
Smith-Waterman score: 3485; 99.8% identity (99.8% similar) in 533 aa overlap (1-533:1-533)
10 20 30 40 50 60
pF1KE5 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 LIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 FYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 SEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 KKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFWL
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_954 KKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWL
430 440 450 460 470 480
490 500 510 520 530
pF1KE5 HTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 HTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
490 500 510 520 530
>>NP_954870 (OMIM: 604336) putative tyrosine-protein pho (551 aa)
initn: 3333 init1: 3333 opt: 3333 Z-score: 3313.7 bits: 622.9 E(85289): 7.8e-178
Smith-Waterman score: 3439; 96.6% identity (96.6% similar) in 551 aa overlap (1-533:1-551)
10 20 30 40
pF1KE5 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKES------------------VL
:::::::::::::::::::::::::::::::::::::::: ::
NP_954 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE5 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQF
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_954 IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQF
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE5 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK
490 500 510 520 530 540
530
pF1KE5 MTSSDVVAGSD
:::::::::::
NP_954 MTSSDVVAGSD
550
>>NP_954869 (OMIM: 604336) putative tyrosine-protein pho (513 aa)
initn: 3108 init1: 3108 opt: 3139 Z-score: 3121.8 bits: 587.3 E(85289): 3.8e-167
Smith-Waterman score: 3315; 96.1% identity (96.1% similar) in 533 aa overlap (1-533:1-513)
10 20 30 40 50 60
pF1KE5 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD
::::::::::::::::::::::::::::::::::::::::
NP_954 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKES--------------------
10 20 30 40
70 80 90 100 110 120
pF1KE5 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 LIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 LIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 FYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 FYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 TKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTH
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 SEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 SEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEME
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE5 KKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFWL
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_954 KKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWL
410 420 430 440 450 460
490 500 510 520 530
pF1KE5 HTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 HTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
470 480 490 500 510
>>NP_954863 (OMIM: 606791) phosphatidylinositol 3,4,5-tr (522 aa)
initn: 2920 init1: 2920 opt: 2920 Z-score: 2904.7 bits: 547.1 E(85289): 4.7e-155
Smith-Waterman score: 2920; 84.9% identity (93.5% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KE5 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD
:::::. ... :. : ..::.:::::::. .: ..:.: :::::::::::::::::
NP_954 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL
:::::::::::::::::.::::::::::::.::::::::::::::::::::::::.::::
NP_954 SKIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR
:::::::::: ::::::::::::::::::: :::::.::::::::::::::::::.::::
NP_954 MDVLLRVFVEGRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIPRWTHLVRLLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
::::.:::::.:::::::::.:: ::::::::::::::::::::::::::::::::::::
NP_954 LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVF
::::::.:::::::::::::::::::::::::::::::::: :::::::::::::.::::
NP_954 FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTH
::::::::::::::::::::::: ::::::::.:::::: ::.:::::::::::.:::
NP_954 TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEME
:.::::::::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::
NP_954 SNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 KKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFWL
::::::. :::.::.: .: ::::::.:.:::::::::::::: :::: ::::: :.::.
NP_954 KKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWF
430 440 450 460 470 480
490 500 510 520 530
pF1KE5 HTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
.::::.:::: ::.::::: ::::: .::: .::::::::::
NP_954 NTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
490 500 510 520
>>NP_001277153 (OMIM: 604336) putative tyrosine-protein (413 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2731.7 bits: 514.8 E(85289): 2e-145
Smith-Waterman score: 2744; 99.8% identity (99.8% similar) in 413 aa overlap (121-533:1-413)
100 110 120 130 140 150
pF1KE5 ILADLIFTDSKLYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVI
::::::::::::::::::::::::::::::
NP_001 MDVLLRVFVERRQQYFSDLFNILDTAIIVI
10 20 30
160 170 180 190 200 210
pF1KE5 LLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKR
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE5 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE5 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE5 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNL
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE5 PPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFD
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE5 GPPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYP
340 350 360 370 380 390
520 530
pF1KE5 SDFAVEILFGEKMTSSDVVAGSD
:::::::::::::::::::::::
NP_001 SDFAVEILFGEKMTSSDVVAGSD
400 410
>>NP_570141 (OMIM: 606791) phosphatidylinositol 3,4,5-tr (445 aa)
initn: 2457 init1: 2053 opt: 2066 Z-score: 2059.3 bits: 390.5 E(85289): 5.8e-108
Smith-Waterman score: 2343; 74.4% identity (82.5% similar) in 503 aa overlap (20-522:2-445)
10 20 30 40 50 60
pF1KE5 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD
:.::::.::::.::::::::: .
NP_570 MNESPQTNEFKGTTEEAPAKES-----------------PHT
10 20
70 80 90 100 110 120
pF1KE5 SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFFL
:..: ..:: .. .::::::::::::.::::::::::::::::::::::::.::::
NP_570 SEFKGA--ALVSPISKRIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFFL
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE5 MDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLR
:::::::::: ::::.::::
NP_570 MDVLLRVFVEG----------------------------------------WTHLVRLLR
90 100
190 200 210 220 230 240
pF1KE5 LIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
::::.:::::.:::::::::.:: ::::::::::::::::::::::::::::::::::::
NP_570 LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE5 FYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVF
::::::.:::::::::::::::::::::::::::::::::: :::::::::::::.::::
NP_570 FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE5 TKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTH
::::::::::::::::::::::: ::::::::.:::::: ::.:::::::::::.:::
NP_570 TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE5 SEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEME
:.::::::::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::
NP_570 SNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVME
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE5 KKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFWL
::::::. :::.::.: .: ::::::.:.:::::::::::::: :::: ::::: :.::.
NP_570 KKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWF
350 360 370 380 390 400
490 500 510 520 530
pF1KE5 HTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
.::::.:::: ::.::::: ::::: .::: .::::::::::
NP_570 NTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
410 420 430 440
>>NP_001135440 (OMIM: 606791) phosphatidylinositol 3,4,5 (411 aa)
initn: 2254 init1: 2053 opt: 2058 Z-score: 2051.8 bits: 389.0 E(85289): 1.5e-107
Smith-Waterman score: 2058; 83.5% identity (92.9% similar) in 364 aa overlap (161-522:48-411)
140 150 160 170 180
pF1KE5 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
:... .:. .::::.::::::::.:::
NP_001 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
20 30 40 50 60 70
190 200 210 220 230 240
pF1KE5 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
NP_001 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
80 90 100 110 120 130
250 260 270 280 290 300
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
NP_001 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
140 150 160 170 180 190
310 320 330 340 350 360
pF1KE5 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.::::::
NP_001 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE5 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
NP_001 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
260 270 280 290 300 310
430 440 450 460 470 480
pF1KE5 SLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
:::.::.: .: ::::::.:.:::::::::::::: :::: ::::: :.::..::::.::
NP_001 SLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
320 330 340 350 360 370
490 500 510 520 530
pF1KE5 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
:: ::.::::: ::::: .::: .::::::::::
NP_001 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
380 390 400 410
>>NP_001258779 (OMIM: 606791) phosphatidylinositol 3,4,5 (193 aa)
initn: 1041 init1: 1041 opt: 1041 Z-score: 1048.6 bits: 202.3 E(85289): 1.1e-51
Smith-Waterman score: 1041; 79.8% identity (91.2% similar) in 193 aa overlap (330-522:1-193)
300 310 320 330 340 350
pF1KE5 FTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKT
::::.:::::: ::.:::::::::::.::
NP_001 MVCALLIASEIFLTAEESLYYFGERRTNKT
10 20 30
360 370 380 390 400 410
pF1KE5 HSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEM
::.::::::::::.:::.::::::::::::::::::::::.:::::: : :::.:. :
NP_001 HSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVM
40 50 60 70 80 90
420 430 440 450 460 470
pF1KE5 EKKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFW
:::::::. :::.::.: .: ::::::.:.:::::::::::::: :::: ::::: :.::
NP_001 EKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFW
100 110 120 130 140 150
480 490 500 510 520 530
pF1KE5 LHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
..::::.:::: ::.::::: ::::: .::: .::::::::::
NP_001 FNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
160 170 180 190
>>NP_001291646 (OMIM: 153480,155600,158350,176807,188470 (576 aa)
initn: 742 init1: 553 opt: 633 Z-score: 637.4 bits: 127.8 E(85289): 9.1e-29
Smith-Waterman score: 706; 34.6% identity (60.1% similar) in 396 aa overlap (163-519:146-520)
140 150 160 170 180 190
pF1KE5 QQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIPRWTHLLRLLRLIILLRIFHLFH
:..:.. :: .:: : : . :
NP_001 SSRRSSHYPAAVQSQAAAERGASATAKSRAISILQKKPRHQQLLPS------LSSFFFSH
120 130 140 150 160
200 210 220 230 240 250
pF1KE5 QKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRF
. .. .:.. ::.::::: .:::::::::. ::::.::. .. ::: : .::::
NP_001 RLPDMTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRF
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE5 LDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDL
::.::.:::..::::.:: :: .:. ::.. ..::: : :. . : .....:...:
NP_001 LDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDD
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE5 ENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRT-DKTHSEKFQGVETPS
....:::::.: :::.:.::.:. :.:.: ..:: :: :: .:: ::
NP_001 NHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK------KGVTIPS
290 300 310 320 330 340
380 390 400 410 420
pF1KE5 QKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIY-SIPRY---VRDLKIQIEMEKKVVFST
:.::: :.. .: . .: : . .. : ... .:: . . . .. . . : ..:.
NP_001 QRRYVYYYS---YLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE5 ISLGKCSVLDNITTDKILIDVFDGP-PLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFI-
: : ::.. : : :. :.::.::... . :.::..: ::
NP_001 NS-GPTR-----REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIP
410 420 430 440 450
490 500 510
pF1KE5 ----------------------------ENNRLYL----PKNELDNLHKQKARRIYPSDF
.:.. :: ::.::. .:.:: : . .:
NP_001 GPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNF
460 470 480 490 500 510
520 530
pF1KE5 AVEILFGEKMTSSDVVAGSD
:.. :
NP_001 KVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQIT
520 530 540 550 560 570
>>NP_000305 (OMIM: 153480,155600,158350,176807,188470,27 (403 aa)
initn: 742 init1: 553 opt: 616 Z-score: 622.8 bits: 124.5 E(85289): 5.9e-28
Smith-Waterman score: 689; 35.4% identity (61.0% similar) in 362 aa overlap (197-519:1-347)
170 180 190 200 210 220
pF1KE5 RNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTE
. .:.. ::.::::: .:::::::::.
NP_000 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP
10 20 30
230 240 250 260 270 280
pF1KE5 RIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMI
::::.::. .. ::: : .::::::.::.:::..::::.:: :: .:. ::.. .
NP_000 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE5 DDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKE
.::: : :. . : .....:...: ....:::::.: :::.:.::.:. :.:
NP_000 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE5 SLYYFGERRT-DKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIY-
.: ..:: :: :: .:: :::.::: :.. .: . .: : . .. : ...
NP_000 ALDFYGEVRTRDK------KGVTIPSQRRYVYYYS---YLLKNHLDYRPVALLFHKMMFE
160 170 180 190 200
410 420 430 440 450 460
pF1KE5 SIPRY---VRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGP-PLYDDVKV
.:: . . . .. . . : ..:. : : ::.. : : :. :.::
NP_000 TIPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTR-----REDKFMYFEFPQPLPVCGDIKV
210 220 230 240 250
470 480 490
pF1KE5 QFFYSNLPTYYDNCSFYFWLHTSFI-----------------------------ENNRLY
.::... . :.::..: :: .:.. :
NP_000 EFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEY
260 270 280 290 300 310
500 510 520 530
pF1KE5 L----PKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
: ::.::. .:.:: : . .: :.. :
NP_000 LVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPD
320 330 340 350 360 370
NP_000 HYRYSDTTDSDPENEPFDEDQHTQITKV
380 390 400
533 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:06:59 2016 done: Tue Nov 8 05:07:00 2016
Total Scan time: 8.240 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]