Result of FASTA (omim) for
pFN21AE5602
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5602, 579 aa
1>>>pF1KE5602 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.9183+/-0.000423; mu= -10.7142+/- 0.026
mean_var=385.6714+/-81.724, 0's: 0 Z-trim(121.9): 13 B-trim: 2188 in 1/58
Lambda= 0.065308
statistics sampled from 39139 (39152) to 39139 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.459), width: 16
Scan time: 8.730
The best scores are: opt bits E(85289)
NP_057342 (OMIM: 610640) YTH domain-containing fam ( 579) 3964 387.7 5.7e-107
NP_001166599 (OMIM: 610640) YTH domain-containing ( 579) 3964 387.7 5.7e-107
NP_001166299 (OMIM: 610640) YTH domain-containing ( 529) 3625 355.7 2.2e-97
NP_060268 (OMIM: 616529) YTH domain-containing fam ( 559) 1367 143.0 2.5e-33
>>NP_057342 (OMIM: 610640) YTH domain-containing family (579 aa)
initn: 3964 init1: 3964 opt: 3964 Z-score: 2041.4 bits: 387.7 E(85289): 5.7e-107
Smith-Waterman score: 3964; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KE5 MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV
490 500 510 520 530 540
550 560 570
pF1KE5 LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
:::::::::::::::::::::::::::::::::::::::
NP_057 LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
550 560 570
>>NP_001166599 (OMIM: 610640) YTH domain-containing fami (579 aa)
initn: 3964 init1: 3964 opt: 3964 Z-score: 2041.4 bits: 387.7 E(85289): 5.7e-107
Smith-Waterman score: 3964; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KE5 MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV
490 500 510 520 530 540
550 560 570
pF1KE5 LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
:::::::::::::::::::::::::::::::::::::::
NP_001 LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
550 560 570
>>NP_001166299 (OMIM: 610640) YTH domain-containing fami (529 aa)
initn: 3625 init1: 3625 opt: 3625 Z-score: 1869.3 bits: 355.7 E(85289): 2.2e-97
Smith-Waterman score: 3625; 100.0% identity (100.0% similar) in 529 aa overlap (51-579:1-529)
30 40 50 60 70 80
pF1KE5 GSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGD
::::::::::::::::::::::::::::::
NP_001 MSDSYLPSYYSPSIGFSYSLGEAAWSTGGD
10 20 30
90 100 110 120 130 140
pF1KE5 TAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 GQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAPGMNTIDQGMAALKLGSTEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAPGMNTIDQGMAALKLGSTEVA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE5 SNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIA
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE5 GSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQA
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE5 SVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGS
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE5 TPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNK
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE5 RLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWI
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE5 FVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHY
460 470 480 490 500 510
570
pF1KE5 EKRQEEEESVKKERQGRGK
:::::::::::::::::::
NP_001 EKRQEEEESVKKERQGRGK
520
>>NP_060268 (OMIM: 616529) YTH domain-containing family (559 aa)
initn: 2031 init1: 1192 opt: 1367 Z-score: 719.2 bits: 143.0 E(85289): 2.5e-33
Smith-Waterman score: 2514; 65.6% identity (83.8% similar) in 585 aa overlap (1-579:1-558)
10 20 30 40 50 60
pF1KE5 MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
:::.:. :: ::: :::::::.:::: ..:.::::::. :. .:.: .::: :: :::
NP_060 MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
::::: :::.:: :::.:: .::::.:::::::. ::. ::.:::::.::.. . ::
NP_060 PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIY--QH
70 80 90 100 110
130 140 150 160 170 180
pF1KE5 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
::::: . :::::...::::.::::.:.:.:.: ::::::...::: .: ..::.:::
NP_060 RFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
:::...:::..::.: .:.:.. :.:::.:.: ..:. ....:. ... ::.:::
NP_060 GMNSLEQGMVGLKIG--DVSSSAVKTVGSVVSSVALTG-VLSGNGGTNVNMPVSKPTSWA
180 190 200 210 220 230
250 260 270 280 290
pF1KE5 DIASKPAKQQPKLKTKNG-IAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQP
::::::: :::.:::.: . :..::::::::::::::::::::: ::: . :. .:
NP_060 AIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP---VPQQAPSP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 TQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQP-TRWVAPRNRG
:..::: :: :: :::: :: :: . :. : :::::::::.
NP_060 -QAAPQP--QQ------VA--------QPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRN
300 310 320 330
360 370 380 390 400 410
pF1KE5 SGFGHNG---VDGNGVGQSQAGSGSTPS-EPHPVLEKLRSINNYNPKDFDWNLKHGRVFI
..::..: :.:. :. : .: .:: : :::::::.. ..::::.:.:::: :::::
NP_060 AAFGQSGGAGSDSNSPGNVQPNS--APSVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFI
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE5 IKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMK
:::::::::::::::.:::::::::::::.:.: :..:::::::::::::::::::::::
NP_060 IKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMK
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE5 SAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPL
: :::.: :::::::::::.:::.:::::::::.::::::::::.:::::::::::::::
NP_060 SPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPL
460 470 480 490 500 510
540 550 560 570
pF1KE5 EKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
::::::::::.::::::::::::.:::::::::: :.::::.:.:
NP_060 EKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ
520 530 540 550
579 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:02:27 2016 done: Tue Nov 8 05:02:28 2016
Total Scan time: 8.730 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]