Result of FASTA (omim) for
pFN21AE5570
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5570, 455 aa
1>>>pF1KE5570 455 - 455 aa - 455 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5054+/-0.000616; mu= -5.7166+/- 0.038
mean_var=690.2740+/-157.840, 0's: 0 Z-trim(116.0): 1343 B-trim: 1412 in 1/57
Lambda= 0.048816
statistics sampled from 24935 (26915) to 24935 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.316), width: 16
Scan time: 8.490
The best scores are: opt bits E(85289)
NP_598407 (OMIM: 609479,616890) mitogen-activated ( 455) 3030 229.4 1.5e-59
XP_016859812 (OMIM: 609479,616890) PREDICTED: mito ( 455) 3030 229.4 1.5e-59
XP_016859813 (OMIM: 609479,616890) PREDICTED: mito ( 455) 3030 229.4 1.5e-59
NP_057737 (OMIM: 609479,616890) mitogen-activated ( 800) 2221 172.8 2.9e-42
XP_005246697 (OMIM: 609479,616890) PREDICTED: mito ( 800) 2221 172.8 2.9e-42
XP_005269197 (OMIM: 600447) PREDICTED: mitogen-act ( 453) 739 68.1 5.7e-11
XP_016875445 (OMIM: 600447) PREDICTED: mitogen-act ( 859) 743 68.8 6.5e-11
NP_006292 (OMIM: 600447) mitogen-activated protein ( 859) 743 68.8 6.5e-11
XP_011537027 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 743 68.8 6.6e-11
XP_006719651 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 743 68.8 6.6e-11
XP_005269195 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 743 68.8 6.6e-11
NP_001180440 (OMIM: 600447) mitogen-activated prot ( 892) 743 68.8 6.6e-11
XP_016862946 (OMIM: 604915) PREDICTED: mitogen-act ( 817) 737 68.3 8.4e-11
NP_001229243 (OMIM: 604915) mitogen-activated prot ( 966) 737 68.5 9.2e-11
NP_004712 (OMIM: 604915) mitogen-activated protein ( 966) 737 68.5 9.2e-11
XP_016862945 (OMIM: 604915) PREDICTED: mitogen-act ( 966) 737 68.5 9.2e-11
XP_011511612 (OMIM: 604915) PREDICTED: mitogen-act ( 966) 737 68.5 9.2e-11
XP_005267740 (OMIM: 600136) PREDICTED: mitogen-act (1081) 704 66.2 4.9e-10
NP_001271159 (OMIM: 600136) mitogen-activated prot (1104) 704 66.2 4.9e-10
NP_149132 (OMIM: 600136) mitogen-activated protein (1118) 704 66.2 5e-10
XP_011535090 (OMIM: 600136) PREDICTED: mitogen-act (1166) 704 66.3 5.1e-10
NP_002437 (OMIM: 600137) mitogen-activated protein ( 954) 696 65.6 6.8e-10
NP_002410 (OMIM: 600050) mitogen-activated protein ( 847) 682 64.5 1.3e-09
XP_011525284 (OMIM: 600137) PREDICTED: mitogen-act ( 860) 662 63.1 3.4e-09
XP_011525283 (OMIM: 600137) PREDICTED: mitogen-act ( 962) 662 63.2 3.6e-09
NP_001229246 (OMIM: 604915) mitogen-activated prot ( 759) 647 62.0 6.6e-09
XP_016862948 (OMIM: 604915) PREDICTED: mitogen-act ( 734) 615 59.7 3.1e-08
XP_016862947 (OMIM: 604915) PREDICTED: mitogen-act ( 734) 615 59.7 3.1e-08
XP_011542607 (OMIM: 614793) PREDICTED: mitogen-act ( 905) 601 58.8 6.8e-08
NP_115811 (OMIM: 614793) mitogen-activated protein (1036) 601 58.9 7.3e-08
NP_663306 (OMIM: 157800,602614,617137) mitogen-act ( 491) 571 56.3 2.2e-07
NP_663305 (OMIM: 157800,602614,617137) mitogen-act ( 518) 571 56.3 2.2e-07
NP_003179 (OMIM: 157800,602614,617137) mitogen-act ( 579) 571 56.4 2.3e-07
NP_663304 (OMIM: 157800,602614,617137) mitogen-act ( 606) 571 56.4 2.4e-07
NP_001161711 (OMIM: 164690) Abelson tyrosine-prote (1043) 538 54.5 1.6e-06
NP_001161710 (OMIM: 164690) Abelson tyrosine-prote (1058) 538 54.5 1.6e-06
NP_001129472 (OMIM: 164690) Abelson tyrosine-prote (1064) 538 54.5 1.6e-06
NP_001161709 (OMIM: 164690) Abelson tyrosine-prote (1079) 538 54.5 1.6e-06
XP_005245145 (OMIM: 164690) PREDICTED: Abelson tyr (1146) 538 54.6 1.7e-06
NP_001161708 (OMIM: 164690) Abelson tyrosine-prote (1161) 538 54.6 1.7e-06
NP_005149 (OMIM: 164690) Abelson tyrosine-protein (1167) 538 54.6 1.7e-06
NP_009298 (OMIM: 164690) Abelson tyrosine-protein (1182) 538 54.6 1.7e-06
XP_016856524 (OMIM: 164690) PREDICTED: Abelson tyr (1182) 538 54.6 1.7e-06
NP_001129473 (OMIM: 164690) Abelson tyrosine-prote ( 542) 528 53.3 1.8e-06
NP_005148 (OMIM: 189980) tyrosine-protein kinase A (1130) 535 54.3 1.9e-06
NP_009297 (OMIM: 189980) tyrosine-protein kinase A (1149) 535 54.4 1.9e-06
XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 499 51.3 7.6e-06
XP_016866140 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 499 51.3 7.6e-06
XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 499 51.3 7.6e-06
XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537) 499 51.3 7.6e-06
>>NP_598407 (OMIM: 609479,616890) mitogen-activated prot (455 aa)
initn: 3030 init1: 3030 opt: 3030 Z-score: 1190.0 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 3030; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 TATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRGK
370 380 390 400 410 420
430 440 450
pF1KE5 KVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
:::::::::::::::::::::::::::::::::::
NP_598 KVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
430 440 450
>>XP_016859812 (OMIM: 609479,616890) PREDICTED: mitogen- (455 aa)
initn: 3030 init1: 3030 opt: 3030 Z-score: 1190.0 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 3030; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRGK
370 380 390 400 410 420
430 440 450
pF1KE5 KVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
:::::::::::::::::::::::::::::::::::
XP_016 KVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
430 440 450
>>XP_016859813 (OMIM: 609479,616890) PREDICTED: mitogen- (455 aa)
initn: 3030 init1: 3030 opt: 3030 Z-score: 1190.0 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 3030; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRGK
370 380 390 400 410 420
430 440 450
pF1KE5 KVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
:::::::::::::::::::::::::::::::::::
XP_016 KVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
430 440 450
>>NP_057737 (OMIM: 609479,616890) mitogen-activated prot (800 aa)
initn: 2215 init1: 2215 opt: 2221 Z-score: 879.8 bits: 172.8 E(85289): 2.9e-42
Smith-Waterman score: 2226; 78.3% identity (86.0% similar) in 456 aa overlap (1-441:1-454)
10 20 30 40 50 60
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
250 260 270 280 290 300
310 320 330 340 350
pF1KE5 LSFKEQELKERERRLKMWEQKLTEQSNTPLL--LPLAARMSEESYFESKT---EESNSAE
::::::::::::::::::::::::::::::: . ..: .. : . . ..:::
NP_057 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
310 320 330 340 350 360
360 370 380 390 400
pF1KE5 MSCQIT--ATSNGEGHGM----NPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINM----Q
:: . .: :. . . .:. : ... : :. ...: . . ::.
NP_057 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDY-INLFHFPP
370 380 390 400 410
410 420 430 440 450
pF1KE5 AKQNSSKTTSKRRGKKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
..:. . . : ::. : :. : :. : .:
NP_057 LIKDSGGEPEENEEKIVNLELVFG-FHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTF
420 430 440 450 460 470
NP_057 NTNLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTK
480 490 500 510 520 530
>>XP_005246697 (OMIM: 609479,616890) PREDICTED: mitogen- (800 aa)
initn: 2215 init1: 2215 opt: 2221 Z-score: 879.8 bits: 172.8 E(85289): 2.9e-42
Smith-Waterman score: 2226; 78.3% identity (86.0% similar) in 456 aa overlap (1-441:1-454)
10 20 30 40 50 60
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
250 260 270 280 290 300
310 320 330 340 350
pF1KE5 LSFKEQELKERERRLKMWEQKLTEQSNTPLL--LPLAARMSEESYFESKT---EESNSAE
::::::::::::::::::::::::::::::: . ..: .. : . . ..:::
XP_005 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
310 320 330 340 350 360
360 370 380 390 400
pF1KE5 MSCQIT--ATSNGEGHGM----NPSLQAMMLMGFGDIFSMNKAGAVMHSGMQINM----Q
:: . .: :. . . .:. : ... : :. ...: . . ::.
XP_005 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDY-INLFHFPP
370 380 390 400 410
410 420 430 440 450
pF1KE5 AKQNSSKTTSKRRGKKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
..:. . . : ::. : :. : :. : .:
XP_005 LIKDSGGEPEENEEKIVNLELVFG-FHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTF
420 430 440 450 460 470
XP_005 NTNLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTK
480 490 500 510 520 530
>>XP_005269197 (OMIM: 600447) PREDICTED: mitogen-activat (453 aa)
initn: 584 init1: 358 opt: 739 Z-score: 318.0 bits: 68.1 E(85289): 5.7e-11
Smith-Waterman score: 739; 39.9% identity (70.5% similar) in 308 aa overlap (10-313:152-449)
10 20 30
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
.. :... .. :.:. :.:. ... .
XP_005 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
130 140 150 160 170
40 50 60 70 80 90
pF1KE5 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
.::::::. . ::..: : :.: ::: : :: . : : :. :. . :.::. . ..
XP_005 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE5 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
: .. .. :. .: ::.:::.. :.::::::: :..:. : :.:: :::.:.
XP_005 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE5 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
. ...:.::..:: :::::::.. :::: : .:.::::::.:: :.:.: ... . :
XP_005 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE5 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
: .. .: .::::: .: ::.:::.. ..::::.::. :. : :. : :.. .
XP_005 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE5 FLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLA
.....:::: :.. .:..:. : :.:: :.:
XP_005 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELR
420 430 440 450
340 350 360 370 380 390
pF1KE5 ARMSEESYFESKTEESNSAEMSCQITATSNGEGHGMNPSLQAMMLMGFGDIFSMNKAGAV
>>XP_016875445 (OMIM: 600447) PREDICTED: mitogen-activat (859 aa)
initn: 614 init1: 358 opt: 743 Z-score: 317.0 bits: 68.8 E(85289): 6.5e-11
Smith-Waterman score: 743; 38.1% identity (69.2% similar) in 341 aa overlap (10-338:119-447)
10 20 30
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
.. :... .. :.:. :.:. ... .
XP_016 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
.::::::. . ::..: : :.: ::: : :: . : : :. :. . :.::. . ..
XP_016 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
: .. .. :. .: ::.:::.. :.::::::: :..:. : :.:: :::.:.
XP_016 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
. ...:.::..:: :::::::.. :::: : .:.::::::.:: :.:.: ... . :
XP_016 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
: .. .: .::::: .: ::.:::.. ..::::.::. :. : :. : :.. .
XP_016 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
330 340 350 360 370
280 290 300 310 320
pF1KE5 FLHNKAEWRCEIEATLERLK-------KLERDLSFKE-QELKERERRLKMWEQKLTEQSN
.....:::: :.. .:..: .::..: ... .::.. . .:.:: . .:
XP_016 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
380 390 400 410 420 430
330 340 350 360 370 380
pF1KE5 TPLLLPLAARMSEESYFESKTEESNSAEMSCQITATSNGEGHGMNPSLQAMMLMGFGDIF
: . : : :
XP_016 --LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVP
440 450 460 470 480 490
>>NP_006292 (OMIM: 600447) mitogen-activated protein kin (859 aa)
initn: 614 init1: 358 opt: 743 Z-score: 317.0 bits: 68.8 E(85289): 6.5e-11
Smith-Waterman score: 743; 38.1% identity (69.2% similar) in 341 aa overlap (10-338:119-447)
10 20 30
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
.. :... .. :.:. :.:. ... .
NP_006 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
.::::::. . ::..: : :.: ::: : :: . : : :. :. . :.::. . ..
NP_006 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
: .. .. :. .: ::.:::.. :.::::::: :..:. : :.:: :::.:.
NP_006 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
. ...:.::..:: :::::::.. :::: : .:.::::::.:: :.:.: ... . :
NP_006 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
: .. .: .::::: .: ::.:::.. ..::::.::. :. : :. : :.. .
NP_006 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
330 340 350 360 370
280 290 300 310 320
pF1KE5 FLHNKAEWRCEIEATLERLK-------KLERDLSFKE-QELKERERRLKMWEQKLTEQSN
.....:::: :.. .:..: .::..: ... .::.. . .:.:: . .:
NP_006 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
380 390 400 410 420 430
330 340 350 360 370 380
pF1KE5 TPLLLPLAARMSEESYFESKTEESNSAEMSCQITATSNGEGHGMNPSLQAMMLMGFGDIF
: . : : :
NP_006 --LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVP
440 450 460 470 480 490
>>XP_011537027 (OMIM: 600447) PREDICTED: mitogen-activat (892 aa)
initn: 522 init1: 358 opt: 743 Z-score: 316.8 bits: 68.8 E(85289): 6.6e-11
Smith-Waterman score: 743; 38.1% identity (69.2% similar) in 341 aa overlap (10-338:152-480)
10 20 30
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
.. :... .. :.:. :.:. ... .
XP_011 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
130 140 150 160 170
40 50 60 70 80 90
pF1KE5 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
.::::::. . ::..: : :.: ::: : :: . : : :. :. . :.::. . ..
XP_011 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE5 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
: .. .. :. .: ::.:::.. :.::::::: :..:. : :.:: :::.:.
XP_011 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE5 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
. ...:.::..:: :::::::.. :::: : .:.::::::.:: :.:.: ... . :
XP_011 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE5 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
: .. .: .::::: .: ::.:::.. ..::::.::. :. : :. : :.. .
XP_011 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
360 370 380 390 400 410
280 290 300 310 320
pF1KE5 FLHNKAEWRCEIEATLERLK-------KLERDLSFKE-QELKERERRLKMWEQKLTEQSN
.....:::: :.. .:..: .::..: ... .::.. . .:.:: . .:
XP_011 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
420 430 440 450 460 470
330 340 350 360 370 380
pF1KE5 TPLLLPLAARMSEESYFESKTEESNSAEMSCQITATSNGEGHGMNPSLQAMMLMGFGDIF
: . : : :
XP_011 --LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVP
480 490 500 510 520
>>XP_006719651 (OMIM: 600447) PREDICTED: mitogen-activat (892 aa)
initn: 522 init1: 358 opt: 743 Z-score: 316.8 bits: 68.8 E(85289): 6.6e-11
Smith-Waterman score: 743; 38.1% identity (69.2% similar) in 341 aa overlap (10-338:152-480)
10 20 30
pF1KE5 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
.. :... .. :.:. :.:. ... .
XP_006 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
130 140 150 160 170
40 50 60 70 80 90
pF1KE5 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
.::::::. . ::..: : :.: ::: : :: . : : :. :. . :.::. . ..
XP_006 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE5 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
: .. .. :. .: ::.:::.. :.::::::: :..:. : :.:: :::.:.
XP_006 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE5 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
. ...:.::..:: :::::::.. :::: : .:.::::::.:: :.:.: ... . :
XP_006 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE5 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
: .. .: .::::: .: ::.:::.. ..::::.::. :. : :. : :.. .
XP_006 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
360 370 380 390 400 410
280 290 300 310 320
pF1KE5 FLHNKAEWRCEIEATLERLK-------KLERDLSFKE-QELKERERRLKMWEQKLTEQSN
.....:::: :.. .:..: .::..: ... .::.. . .:.:: . .:
XP_006 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
420 430 440 450 460 470
330 340 350 360 370 380
pF1KE5 TPLLLPLAARMSEESYFESKTEESNSAEMSCQITATSNGEGHGMNPSLQAMMLMGFGDIF
: . : : :
XP_006 --LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVP
480 490 500 510 520
455 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:56:30 2016 done: Tue Nov 8 01:56:31 2016
Total Scan time: 8.490 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]