Result of FASTA (omim) for
pFN21AE5566
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5566, 439 aa
1>>>pF1KE5566 439 - 439 aa - 439 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8899+/-0.000395; mu= 14.3745+/- 0.025
mean_var=79.3843+/-16.469, 0's: 0 Z-trim(112.7): 32 B-trim: 24 in 1/52
Lambda= 0.143948
statistics sampled from 21746 (21769) to 21746 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.255), width: 16
Scan time: 7.830
The best scores are: opt bits E(85289)
NP_001171730 (OMIM: 609134) E3 ubiquitin-protein l ( 439) 3002 633.4 3.6e-181
XP_016866085 (OMIM: 609134) PREDICTED: E3 ubiquiti (1754) 2926 617.9 6.5e-176
XP_005249022 (OMIM: 609134) PREDICTED: E3 ubiquiti (1755) 2926 617.9 6.5e-176
NP_056070 (OMIM: 609134) E3 ubiquitin-protein liga (1755) 2846 601.3 6.5e-171
XP_016866086 (OMIM: 609134) PREDICTED: E3 ubiquiti (1260) 2773 586.0 1.8e-166
XP_016866084 (OMIM: 609134) PREDICTED: E3 ubiquiti (1781) 2773 586.1 2.4e-166
XP_011512740 (OMIM: 609134) PREDICTED: E3 ubiquiti (1782) 2773 586.1 2.4e-166
XP_016866083 (OMIM: 609134) PREDICTED: E3 ubiquiti (1782) 2693 569.5 2.4e-161
NP_777576 (OMIM: 243800,605981) E3 ubiquitin-prote (1749) 1433 307.8 1.4e-82
XP_016858848 (OMIM: 613831) PREDICTED: E3 ubiquiti (1247) 306 73.7 3e-12
XP_016858847 (OMIM: 613831) PREDICTED: E3 ubiquiti (1478) 306 73.7 3.5e-12
XP_011508906 (OMIM: 613831) PREDICTED: E3 ubiquiti (1514) 306 73.8 3.6e-12
XP_016858846 (OMIM: 613831) PREDICTED: E3 ubiquiti (1514) 306 73.8 3.6e-12
XP_016858845 (OMIM: 613831) PREDICTED: E3 ubiquiti (1612) 306 73.8 3.8e-12
NP_742067 (OMIM: 613831) E3 ubiquitin-protein liga (1888) 306 73.8 4.3e-12
XP_006712334 (OMIM: 613831) PREDICTED: E3 ubiquiti (1891) 306 73.8 4.3e-12
XP_006712332 (OMIM: 613831) PREDICTED: E3 ubiquiti (1892) 306 73.8 4.3e-12
XP_005246357 (OMIM: 613831) PREDICTED: E3 ubiquiti (1899) 306 73.8 4.3e-12
XP_006712331 (OMIM: 613831) PREDICTED: E3 ubiquiti (1902) 306 73.8 4.3e-12
XP_005246356 (OMIM: 613831) PREDICTED: E3 ubiquiti (1903) 306 73.8 4.3e-12
XP_006712333 (OMIM: 613831) PREDICTED: E3 ubiquiti (1855) 287 69.9 6.5e-11
>>NP_001171730 (OMIM: 609134) E3 ubiquitin-protein ligas (439 aa)
initn: 3002 init1: 3002 opt: 3002 Z-score: 3373.6 bits: 633.4 E(85289): 3.6e-181
Smith-Waterman score: 3002; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:1-439)
10 20 30 40 50 60
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
370 380 390 400 410 420
430
pF1KE5 IFTVPSLFSISAGRSGSPL
:::::::::::::::::::
NP_001 IFTVPSLFSISAGRSGSPL
430
>>XP_016866085 (OMIM: 609134) PREDICTED: E3 ubiquitin-pr (1754 aa)
initn: 2926 init1: 2926 opt: 2926 Z-score: 3279.2 bits: 617.9 E(85289): 6.5e-176
Smith-Waterman score: 2926; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
370 380 390 400 410 420
430
pF1KE5 IFTVPSLFSISAGRSGSPL
:::::::
XP_016 IFTVPSLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD
430 440 450 460 470 480
>>XP_005249022 (OMIM: 609134) PREDICTED: E3 ubiquitin-pr (1755 aa)
initn: 2926 init1: 2926 opt: 2926 Z-score: 3279.2 bits: 617.9 E(85289): 6.5e-176
Smith-Waterman score: 2926; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
370 380 390 400 410 420
430
pF1KE5 IFTVPSLFSISAGRSGSPL
:::::::
XP_005 IFTVPSLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD
430 440 450 460 470 480
>>NP_056070 (OMIM: 609134) E3 ubiquitin-protein ligase U (1755 aa)
initn: 2846 init1: 2846 opt: 2846 Z-score: 3189.4 bits: 601.3 E(85289): 6.5e-171
Smith-Waterman score: 2846; 96.7% identity (98.8% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
::::::::::::::::::::::::::::::::::::..:: :.. :::.: ::. ::::
NP_056 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQ
370 380 390 400 410 420
430
pF1KE5 IFTVPSLFSISAGRSGSPL
.::.:.:
NP_056 FFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD
430 440 450 460 470 480
>>XP_016866086 (OMIM: 609134) PREDICTED: E3 ubiquitin-pr (1260 aa)
initn: 2773 init1: 2773 opt: 2773 Z-score: 3109.6 bits: 586.0 E(85289): 1.8e-166
Smith-Waterman score: 2773; 100.0% identity (100.0% similar) in 402 aa overlap (26-427:53-454)
10 20 30 40 50
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPN
::::::::::::::::::::::::::::::
XP_016 AAPVGRNRLLDVLEQPDPDLGKQLCRPSPCGKWLQATDLTREVYQHLAHYVPKIYCRGPN
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE5 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE5 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE5 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE5 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
390 400 410 420 430 440
420 430
pF1KE5 DLSVQIFTVPSLFSISAGRSGSPL
::::::::::::
XP_016 DLSVQIFTVPSLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQ
450 460 470 480 490 500
>>XP_016866084 (OMIM: 609134) PREDICTED: E3 ubiquitin-pr (1781 aa)
initn: 2773 init1: 2773 opt: 2773 Z-score: 3107.3 bits: 586.1 E(85289): 2.4e-166
Smith-Waterman score: 2773; 100.0% identity (100.0% similar) in 402 aa overlap (26-427:53-454)
10 20 30 40 50
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPN
::::::::::::::::::::::::::::::
XP_016 AAPVGRNRLLDVLEQPDPDLGKQLCRPSPCGKWLQATDLTREVYQHLAHYVPKIYCRGPN
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE5 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE5 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE5 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE5 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
390 400 410 420 430 440
420 430
pF1KE5 DLSVQIFTVPSLFSISAGRSGSPL
::::::::::::
XP_016 DLSVQIFTVPSLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQ
450 460 470 480 490 500
>>XP_011512740 (OMIM: 609134) PREDICTED: E3 ubiquitin-pr (1782 aa)
initn: 2773 init1: 2773 opt: 2773 Z-score: 3107.3 bits: 586.1 E(85289): 2.4e-166
Smith-Waterman score: 2773; 100.0% identity (100.0% similar) in 402 aa overlap (26-427:53-454)
10 20 30 40 50
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPN
::::::::::::::::::::::::::::::
XP_011 AAPVGRNRLLDVLEQPDPDLGKQLCRPSPCGKWLQATDLTREVYQHLAHYVPKIYCRGPN
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE5 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE5 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE5 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE5 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
390 400 410 420 430 440
420 430
pF1KE5 DLSVQIFTVPSLFSISAGRSGSPL
::::::::::::
XP_011 DLSVQIFTVPSLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQ
450 460 470 480 490 500
>>XP_016866083 (OMIM: 609134) PREDICTED: E3 ubiquitin-pr (1782 aa)
initn: 2693 init1: 2693 opt: 2693 Z-score: 3017.5 bits: 569.5 E(85289): 2.4e-161
Smith-Waterman score: 2693; 96.5% identity (98.8% similar) in 402 aa overlap (26-427:53-454)
10 20 30 40 50
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPN
::::::::::::::::::::::::::::::
XP_016 AAPVGRNRLLDVLEQPDPDLGKQLCRPSPCGKWLQATDLTREVYQHLAHYVPKIYCRGPN
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE5 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDC
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEE
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDPLVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDE
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE5 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQT
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE5 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRL
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE5 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVA
:::::::::::::::::::::::::::::::::::::::::..:: :.. :::.: ::.
XP_016 MLSDSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVT
390 400 410 420 430 440
420 430
pF1KE5 DLSVQIFTVPSLFSISAGRSGSPL
::::.::.:.:
XP_016 ALSVQFFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQ
450 460 470 480 490 500
>>NP_777576 (OMIM: 243800,605981) E3 ubiquitin-protein l (1749 aa)
initn: 1332 init1: 870 opt: 1433 Z-score: 1603.5 bits: 307.8 E(85289): 1.4e-82
Smith-Waterman score: 1433; 48.8% identity (78.9% similar) in 412 aa overlap (17-427:18-427)
10 20 30 40 50
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQ
: . ...:. : : .:. .:::. ::.:: .: .
NP_777 MADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 KEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDP
:.. .: .. :.:::: :::: . . ::.... .::::::: :: ::::::::.::
NP_777 KQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGA-FQLCGRVFKSGETTYSCRDCAIDP
70 80 90 100 110
120 130 140 150 160 170
pF1KE5 TCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDP
::::::.:: :.:..:::.: :: :::::::::::::: ::.: .:: . . .: .
NP_777 TCVLCMDCFQDSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVNHEPGRAGTIKE-NS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 LVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTY
:.:.::... .:: ...:.::. ::.:.::: .:.. ::.. :::.::::: :.:
NP_777 RCPLNEEVIVQARKIFPSVIKYVVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 EQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTK-PL
..:::.::.:..: :: .:..:..:::.:. : . :..:: : .. .. ::
NP_777 DHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGAYAACQEAKEDIKSHSENVSQHPL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 KVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLS
.:.:.:: :.:::.:.:.: ::...:..::. .:.:.::. :.: ::.:: :..::::
NP_777 HVEVLHSEIMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLREEPDSENPCLISRLMLW
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 DSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLS
:.::.::::.. :.:..::..:...::::::..:.: :..::..:..::::: .:.. ::
NP_777 DAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHDRSISITALS
360 370 380 390 400 410
420 430
pF1KE5 VQIFTVPSLFSISAGRSGSPL
::.::::.:
NP_777 VQMFTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICD
420 430 440 450 460 470
>>XP_016858848 (OMIM: 613831) PREDICTED: E3 ubiquitin-pr (1247 aa)
initn: 285 init1: 257 opt: 306 Z-score: 340.8 bits: 73.7 E(85289): 3e-12
Smith-Waterman score: 308; 24.7% identity (54.2% similar) in 373 aa overlap (73-423:91-452)
50 60 70 80 90
pF1KE5 AHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANK---PSHLC
.:: : . :. .. : . :. ::
XP_016 AERPLAAAAGGEDAAAAGGGGGPGAAEEEALEWCKCLLAGGGGYDEFCAAVRAYDPAALC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 GRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKE
: :. .. .: :: :...: :: ::: . : : . : : .:: :::::... .:
XP_016 GLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 GPYCQKHEL-NTSEIEEEEDPLVHLSEDVIARTYNIFAITFR--YAVEILTWEKESELPA
. .:..:.. ..:.: :. .:: :. : . .: : .:..:
XP_016 SGFCKRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADGPSEKDLNK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 DLEMVEKSDTYYCML--FNDEVHTY-EQVIYTLQKAVNCTQKEAIGFATTVDRDGRR---
:...: . .. : .. ... ::. . :. . :. ..: . : .. ..
XP_016 VLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTS--GLGENACVKKSHEKYLI
250 260 270 280 290
280 290 300 310 320 330
pF1KE5 SVRYGDFQYCEQAKSVIVRNTSRQTKPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDG
... . . : :. :.. : :. : :: . : : ..: : . : :.:
XP_016 ALKSSGLTYPEDKLVYGVQEPSAGTSSLAVQ---GFIGATGTLGQVDSSDEDDQDG-SQG
300 310 320 330 340 350
340 350 360 370 380
pF1KE5 LRRILCQVGLQEGPDGENSSLVDRL----MLSDSKLWKGARSVYHQL--FMSSLLMDLKY
: . .: :. : ...:..: : .: . .: ... :. ..: : .:
XP_016 LGK-RKRVKLSSGT--KDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEY
360 370 380 390 400 410
390 400 410 420 430
pF1KE5 KKLFAVRFAKNY----ERLQSDYVTDDHDREFSVADLSVQIFTVPSLFSISAGRSGSPL
: :. :...: . :.... .: . . .. .:::.:.
XP_016 KVAFTKTFVQHYAFIMKTLKKSHESDTMSNR--IVHISVQLFSNEELARQVTEECQLLDI
420 430 440 450 460
XP_016 MVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKR
470 480 490 500 510 520
439 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:53:49 2016 done: Tue Nov 8 01:53:50 2016
Total Scan time: 7.830 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]