Result of FASTA (omim) for
pFN21AE5562
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5562, 412 aa
1>>>pF1KE5562 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1622+/-0.000335; mu= 18.0040+/- 0.021
mean_var=70.1714+/-14.040, 0's: 0 Z-trim(115.4): 158 B-trim: 0 in 0/53
Lambda= 0.153107
statistics sampled from 25741 (25903) to 25741 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.304), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
NP_647536 (OMIM: 609756) CHRNA7-FAM7A fusion prote ( 412) 2886 646.6 3.4e-185
XP_011520455 (OMIM: 609756) PREDICTED: CHRNA7-FAM7 ( 412) 2886 646.6 3.4e-185
XP_016877372 (OMIM: 118511,612001) PREDICTED: neur ( 440) 2686 602.4 7e-172
XP_016877371 (OMIM: 118511,612001) PREDICTED: neur ( 441) 2686 602.4 7.1e-172
XP_011519479 (OMIM: 118511,612001) PREDICTED: neur ( 401) 2685 602.2 7.6e-172
XP_011519478 (OMIM: 118511,612001) PREDICTED: neur ( 486) 2685 602.2 8.9e-172
NP_000737 (OMIM: 118511,612001) neuronal acetylcho ( 502) 2685 602.2 9.1e-172
NP_001177384 (OMIM: 118511,612001) neuronal acetyl ( 531) 2685 602.2 9.5e-172
XP_005254807 (OMIM: 609756) PREDICTED: CHRNA7-FAM7 ( 321) 2206 496.3 4.5e-140
NP_683709 (OMIM: 609756) CHRNA7-FAM7A fusion prote ( 321) 2206 496.3 4.5e-140
XP_016877373 (OMIM: 118511,612001) PREDICTED: neur ( 321) 2206 496.3 4.5e-140
XP_011520457 (OMIM: 609756) PREDICTED: CHRNA7-FAM7 ( 290) 1424 323.5 4.2e-88
XP_011519480 (OMIM: 118511,612001) PREDICTED: neur ( 380) 1223 279.2 1.2e-74
NP_001269384 (OMIM: 118502,610353) neuronal acetyl ( 514) 903 208.6 2.9e-53
NP_000733 (OMIM: 118502,610353) neuronal acetylcho ( 529) 903 208.6 2.9e-53
XP_006716345 (OMIM: 118502,610353) PREDICTED: neur ( 529) 903 208.6 2.9e-53
XP_011542690 (OMIM: 118502,610353) PREDICTED: neur ( 529) 903 208.6 2.9e-53
XP_005273454 (OMIM: 118502,610353) PREDICTED: neur ( 370) 884 204.3 4.1e-52
XP_016868492 (OMIM: 118502,610353) PREDICTED: neur ( 370) 884 204.3 4.1e-52
XP_006720445 (OMIM: 118503,612052) PREDICTED: neur ( 438) 870 201.3 4e-51
NP_000734 (OMIM: 118503,612052) neuronal acetylcho ( 505) 870 201.3 4.4e-51
XP_011526826 (OMIM: 118504,188890,600513) PREDICTE ( 556) 785 182.6 2.1e-45
NP_001160166 (OMIM: 118503,612052) neuronal acetyl ( 489) 781 181.6 3.6e-45
XP_016883113 (OMIM: 118504,188890,600513) PREDICTE ( 546) 779 181.2 5.3e-45
NP_000735 (OMIM: 118504,188890,600513) neuronal ac ( 627) 779 181.3 5.9e-45
NP_065135 (OMIM: 606372) neuronal acetylcholine re ( 450) 750 174.8 3.9e-43
XP_011519492 (OMIM: 118509) PREDICTED: neuronal ac ( 424) 749 174.5 4.3e-43
XP_011519493 (OMIM: 118509) PREDICTED: neuronal ac ( 424) 749 174.5 4.3e-43
XP_016877378 (OMIM: 118509) PREDICTED: neuronal ac ( 449) 749 174.6 4.5e-43
XP_016877377 (OMIM: 118509) PREDICTED: neuronal ac ( 462) 749 174.6 4.6e-43
XP_016877376 (OMIM: 118509) PREDICTED: neuronal ac ( 463) 749 174.6 4.6e-43
XP_016877374 (OMIM: 118509) PREDICTED: neuronal ac ( 468) 749 174.6 4.6e-43
XP_016877375 (OMIM: 118509) PREDICTED: neuronal ac ( 468) 749 174.6 4.6e-43
NP_060051 (OMIM: 605116) neuronal acetylcholine re ( 479) 749 174.6 4.7e-43
XP_011519489 (OMIM: 118509) PREDICTED: neuronal ac ( 495) 749 174.6 4.9e-43
XP_011519488 (OMIM: 118509) PREDICTED: neuronal ac ( 495) 749 174.6 4.9e-43
NP_000741 (OMIM: 118509) neuronal acetylcholine re ( 498) 749 174.6 4.9e-43
XP_011542691 (OMIM: 118502,610353) PREDICTED: neur ( 331) 736 171.6 2.6e-42
XP_016868493 (OMIM: 118502,610353) PREDICTED: neur ( 331) 736 171.6 2.6e-42
NP_000739 (OMIM: 118507,605375) neuronal acetylcho ( 502) 735 171.5 4.2e-42
NP_001186208 (OMIM: 606888) neuronal acetylcholine ( 479) 716 167.3 7.4e-41
NP_004189 (OMIM: 606888) neuronal acetylcholine re ( 494) 716 167.3 7.6e-41
NP_000070 (OMIM: 100690,253290,601462,608930) acet ( 457) 692 162.0 2.8e-39
XP_016858746 (OMIM: 100690,253290,601462,608930) P ( 464) 692 162.0 2.8e-39
NP_001034612 (OMIM: 100690,253290,601462,608930) a ( 482) 692 162.0 2.9e-39
XP_016858745 (OMIM: 100690,253290,601462,608930) P ( 489) 692 162.0 3e-39
NP_000736 (OMIM: 118505,612052) neuronal acetylcho ( 468) 644 151.4 4.5e-36
NP_000740 (OMIM: 118508) neuronal acetylcholine re ( 458) 640 150.5 8.1e-36
NP_001243502 (OMIM: 118504,188890,600513) neuronal ( 451) 626 147.4 6.8e-35
XP_016883114 (OMIM: 118504,188890,600513) PREDICTE ( 451) 626 147.4 6.8e-35
>>NP_647536 (OMIM: 609756) CHRNA7-FAM7A fusion protein i (412 aa)
initn: 2886 init1: 2886 opt: 2886 Z-score: 3445.9 bits: 646.6 E(85289): 3.4e-185
Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFKSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFKSSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 YIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 ECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 SLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 TRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 GLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 GLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQ
310 320 330 340 350 360
370 380 390 400 410
pF1KE5 DESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 DESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
370 380 390 400 410
>>XP_011520455 (OMIM: 609756) PREDICTED: CHRNA7-FAM7A fu (412 aa)
initn: 2886 init1: 2886 opt: 2886 Z-score: 3445.9 bits: 646.6 E(85289): 3.4e-185
Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFKSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFKSSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 GLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQ
310 320 330 340 350 360
370 380 390 400 410
pF1KE5 DESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
370 380 390 400 410
>>XP_016877372 (OMIM: 118511,612001) PREDICTED: neuronal (440 aa)
initn: 2685 init1: 2685 opt: 2686 Z-score: 3206.7 bits: 602.4 E(85289): 7e-172
Smith-Waterman score: 2686; 99.5% identity (99.7% similar) in 388 aa overlap (25-412:54-440)
10 20 30 40 50
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPG
:. :::::::::::::::::::::::::::
XP_016 MGCTAGAHSLDPHPRLCSLLCIGEFCGRDGCS-ADERFDATFHTNVLVNSSGHCQYLPPG
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE5 IFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGK
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 RSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISL
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 GITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDG
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE5 GKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNL
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE5 LYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIA
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE5 NRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
390 400 410 420 430 440
>>XP_016877371 (OMIM: 118511,612001) PREDICTED: neuronal (441 aa)
initn: 2685 init1: 2685 opt: 2686 Z-score: 3206.7 bits: 602.4 E(85289): 7.1e-172
Smith-Waterman score: 2686; 99.5% identity (99.7% similar) in 388 aa overlap (25-412:55-441)
10 20 30 40 50
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPG
:. :::::::::::::::::::::::::::
XP_016 MGCTAGAHSLDPHPRLCSLLCIGEFCGRDGCS-ADERFDATFHTNVLVNSSGHCQYLPPG
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE5 IFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGK
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE5 RSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISL
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE5 GITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDG
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE5 GKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNL
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE5 LYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIA
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE5 NRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
390 400 410 420 430 440
>>XP_011519479 (OMIM: 118511,612001) PREDICTED: neuronal (401 aa)
initn: 2685 init1: 2685 opt: 2685 Z-score: 3206.1 bits: 602.2 E(85289): 7.6e-172
Smith-Waterman score: 2685; 100.0% identity (100.0% similar) in 385 aa overlap (28-412:17-401)
10 20 30 40 50 60
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFKSSC
:::::::::::::::::::::::::::::::::
XP_011 MKNIQKSLSHKSLSHSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSC
10 20 30 40
70 80 90 100 110 120
pF1KE5 YIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFY
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 ECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 SLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKW
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 TRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFR
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 GLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQ
290 300 310 320 330 340
370 380 390 400 410
pF1KE5 DESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
350 360 370 380 390 400
>>XP_011519478 (OMIM: 118511,612001) PREDICTED: neuronal (486 aa)
initn: 2685 init1: 2685 opt: 2685 Z-score: 3204.9 bits: 602.2 E(85289): 8.9e-172
Smith-Waterman score: 2685; 100.0% identity (100.0% similar) in 385 aa overlap (28-412:102-486)
10 20 30 40 50
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFK
::::::::::::::::::::::::::::::
XP_011 QWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFK
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE5 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSE
140 150 160 170 180 190
120 130 140 150 160 170
pF1KE5 RFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGIT
200 210 220 230 240 250
180 190 200 210 220 230
pF1KE5 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKM
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE5 PKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYI
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE5 GFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE5 RCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
440 450 460 470 480
>>NP_000737 (OMIM: 118511,612001) neuronal acetylcholine (502 aa)
initn: 2685 init1: 2685 opt: 2685 Z-score: 3204.7 bits: 602.2 E(85289): 9.1e-172
Smith-Waterman score: 2685; 100.0% identity (100.0% similar) in 385 aa overlap (28-412:118-502)
10 20 30 40 50
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFK
::::::::::::::::::::::::::::::
NP_000 QWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFK
90 100 110 120 130 140
60 70 80 90 100 110
pF1KE5 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSE
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE5 RFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGIT
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE5 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKM
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE5 PKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYI
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE5 GFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF
390 400 410 420 430 440
360 370 380 390 400 410
pF1KE5 RCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
450 460 470 480 490 500
>>NP_001177384 (OMIM: 118511,612001) neuronal acetylchol (531 aa)
initn: 2685 init1: 2685 opt: 2685 Z-score: 3204.4 bits: 602.2 E(85289): 9.5e-172
Smith-Waterman score: 2685; 100.0% identity (100.0% similar) in 385 aa overlap (28-412:147-531)
10 20 30 40 50
pF1KE5 MQKYCIYQHFQFQLLIQHLWIAANCDIADERFDATFHTNVLVNSSGHCQYLPPGIFK
::::::::::::::::::::::::::::::
NP_001 QWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFK
120 130 140 150 160 170
60 70 80 90 100 110
pF1KE5 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSE
180 190 200 210 220 230
120 130 140 150 160 170
pF1KE5 RFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGIT
240 250 260 270 280 290
180 190 200 210 220 230
pF1KE5 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKM
300 310 320 330 340 350
240 250 260 270 280 290
pF1KE5 PKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYI
360 370 380 390 400 410
300 310 320 330 340 350
pF1KE5 GFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF
420 430 440 450 460 470
360 370 380 390 400 410
pF1KE5 RCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
480 490 500 510 520 530
>>XP_005254807 (OMIM: 609756) PREDICTED: CHRNA7-FAM7A fu (321 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2635.7 bits: 496.3 E(85289): 4.5e-140
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (92-412:1-321)
70 80 90 100 110 120
pF1KE5 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
XP_005 MQEADISGYIPNGEWDLVGIPGKRSERFYE
10 20 30
130 140 150 160 170 180
pF1KE5 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE5 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE5 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE5 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
220 230 240 250 260 270
370 380 390 400 410
pF1KE5 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
280 290 300 310 320
>>NP_683709 (OMIM: 609756) CHRNA7-FAM7A fusion protein i (321 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2635.7 bits: 496.3 E(85289): 4.5e-140
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (92-412:1-321)
70 80 90 100 110 120
pF1KE5 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
NP_683 MQEADISGYIPNGEWDLVGIPGKRSERFYE
10 20 30
130 140 150 160 170 180
pF1KE5 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE5 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE5 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE5 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
220 230 240 250 260 270
370 380 390 400 410
pF1KE5 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
280 290 300 310 320
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:51:10 2016 done: Tue Nov 8 01:51:11 2016
Total Scan time: 8.120 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]